Faculty

Institution

Unit

Venue

Michail Sitkovsky

Eleanor Black Chair and Professor

Northeastern University

Affiliations

College of Science

Biology

Bouve College of Health Sciences

School of Pharmacy and Pharmaceutical Sciences

Michail Sitkovsky is currently serving as a Biology Eleanor Black Chair and Professor at Northeastern University.

Honors

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Experiences

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Education

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Michail Sitkovsky

Northeastern University

Eleanor Black Chair and Professor

You can click a keyword to filter the displayed items

immunology pharmacology cell biology immune responses medicine cell signaling receptors inflammation oncology hematology hypoxia (medicine) medicinal research tumor biology cancer immunotherapy molecular physiology adaptive immune system cancer treatment receptor (biochemistry) cell regulation immunosuppression cellular physiology cancer biology biological chemistry mammalian biology molecular immunology t-regulatory cell cellular immune responses immunomodulation respiratory medicine lymphocyte development protein science cellular therapy in vivo systems immunosuppressive therapy extracellular atp extracellular adenosine pharmacotherapy cancer care redox biology clinical pharmacology pharmaceutical sciences anti-inflammatory drug development effector functions molecular cancer plo biology cell death clinical microbiology experimental medicine hemostasis cancer management histocompatibility lymphatic system g protein-coupled receptor cytokines signaling pathways clinical immunology chronic inflammation tumor targeting anti-cancer agents developmental immunology functional regulation antigen processing adenosine receptors immune cells hypoxia-adenosinergic immunosuppression cytolytic t-lymphocytes cytotoxic t-lymphocytes hypoxia-inducible factor differential regulation camp-dependent protein kinase protein kinases g-protein-coupled adenosine receptors tissue damage animal models supplemental oxygenation

Notable Scholarly Works

Notable Federal Grants

Collaborators

CORRECTIONS: A2b Adenosine Receptor Expression by Myeloid Cells is Pro-Inflammatory in Murine Allergic-Airway Inflammation. The Journal of Immunology (2024)

Bryan G BelikoffLouis J VaickusMichail SitkovskyDaniel G Remick

immunologyreceptorspharmacologymurine allergic-airway inflammationallergymyeloid cellsintermediate hostinflammation

Oxygen Carrying Nanoemulsions and Respiratory Hyperoxia Eliminate Tumor Hypoxia-Induced Suppression and Improve Cancer Immunotherapy. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Katarina Halpin-VeszeleiovaMichael MallouhAshley AproNuria RomeroCamille BahrMaureen ShinKelly WardLaura RosenbergMichail V. SitkovskyBruce SpiessStephen M. Hatfield

medicinenanomedicinecancer immunotherapyoncologyrespiratory hyperoxiatumor hypoxia-induced suppression

Comprehensive Genome Editing Confers ‘Off-The-Shelf’ Car-T Cells Superior Efficacy Against Solid Tumors. bioRxiv (Cold Spring Harbor Laboratory) (2023)

Ryan MurrayNuria Roxana Romero NavarreteKashvi DesaiMd Raihan ChowdhuryShanmuga Reddy ChilakapatiBrian ChongAngelica MessanaHanna SobonJoe RochaFaith MusengeAdam CamblinGiuseppe CiaramellaMichail SitkovskyColby MaldiniStephen Hatfield

immunologygenomicssolid tumorspharmacologybiomedical engineeringgenome editingtreatment developmentcancer researchtreatment effectscancer genomicscancer immunotherapyoncologymedicinal researchcancer treatmentcancer biology

Targeting Hypoxia‐Adenosinergic Signaling to Enable Effective Anti‐Tumor Responses by Reprogramming the Immunosuppressive Tumor Microenvironment. The FASEB Journal (2022)

Kai BeattieNuria Roxana Romero NavarreteAnushka DongreMichail SitkovskyStephen Hatfield

immunologypharmacologyradiation oncologycancer immunosurveillancetherapeutic targetsadenosine degradationadenosine metabolismadenosine generationcancer cellstumor microenvironmentimmunomodulationimmunosuppressioncellular therapyinflammation

Oxygen‐Generating Cryogels Restore T Cell Mediated Cytotoxicity in Hypoxic Tumors. Advanced Functional Materials (2021)

Thibault ColombaniLoek J. EggermontStephen M. HatfieldZachary J. RogersMahboobeh RezaeeyazdiAdnan MemicMichail V. SitkovskySidi A. Bencherif

immunologydermatologyhypoxic tumorsradiation oncologycancer researchoxygen-generating cryogelstissue engineeringcancer imagingin vivo systemsoncologyadvanced materialst-regulatory cellmedicinal researchcancer cellscancer biologytumor biology

Oxygen‐Generating Cryogels Restore T Cell Mediated Cytotoxicity in Hypoxic Tumors (Adv. Funct. Mater. 37/2021). Advanced Functional Materials (2021)

Thibault ColombaniLoek J. EggermontStephen M. HatfieldZachary J. RogersMahboobeh RezaeeyazdiAdnan MemicMichail V. SitkovskySidi A. Bencherif

materials sciencehypoxic tumorscellular immune responsesin vivo systemstreatment and preventionmaterial researchimmune responsescancer biologycancer researchoxygen-generating cryogelstumor biologyimmunologypharmacologyadvanced functional materialstissue engineeringcancer imagingoncologyt-regulatory cellmedicinal researchcancer cells

Antihypoxic Oxygenation Agents With Respiratory Hyperoxia to Improve Cancer Immunotherapy. Journal of Clinical Investigation (2020)

Stephen M. HatfieldMichail V. Sitkovsky

medicinepharmacologyantihypoxic oxygenation agentsclinical effectivenessrespiratory hyperoxiacancer immunotherapyoncologyclinical researchrespiratory medicinecancer treatmentclinical investigationclinical medicineimmunotherapy

Lessons From the A2A Adenosine Receptor Antagonist–Enabled Tumor Regression and Survival in Patients With Treatment-Refractory Renal Cell Cancer. Cancer Discovery (2020)

Michail V. Sitkovsky

pharmacologycancer carecancer managementradiation oncologycancer researchsurvival analysisurologycancer discoveryanti-cancer agentsdrug discoveryoncologymedicinal researchcancer treatmentcancer biologytumor biology

Sufficient Numbers of Anti-Tumor T Cells is a Condition of Maximal Efficacy of Anti-Hypoxia-A2-Adenosinergic Drugs During Cancer Immunotherapy. Current Opinion in Pharmacology (2020)

Michail V Sitkovsky

pharmacologycancer immunotherapycancer treatmentmaximal efficacyimmunotherapy

Therapeutic Effects of Adenosine in High Flow 21% Oxygen Aereosol in Patients With Covid19-Pneumonia. PLoS ONE (2020)

Pierpaolo CorrealeMassimo CaraccioloFederico BilottaMarco ConteMaria CuzzolaCarmela FalconeCarmelo ManganoAntonella Consuelo FalzeaEleonora IulianoAntonella MorabitoGiuseppe FotiAntonio ArmentanoMichele CaragliaAntonino De LorenzoMichail SitkovskySebastiano Macheda

public healthmedicinepulmonary diseasespulmonary pharmacologycovid-19emergency medicineinfection controlclinical microbiologyinfectious respiratory diseaseveterinary medicinetreatment effectsclinical evidencerespiratory medicinemedicinal researchintensive caretherapeutic effectssepsisinflammation

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Michail Sitkovsky

Eleanor Black Chair and Professor

Northeastern University

Affiliations

College of Science

Biology

Bouve College of Health Sciences

School of Pharmacy and Pharmaceutical Sciences

Michail Sitkovsky is currently serving as a Biology Eleanor Black Chair and Professor at Northeastern University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Michail Sitkovsky

Northeastern University

Eleanor Black Chair and Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

CORRECTIONS: A2b Adenosine Receptor Expression by Myeloid Cells is Pro-Inflammatory in Murine Allergic-Airway Inflammation. The Journal of Immunology (2024)

Bryan G BelikoffLouis J VaickusMichail SitkovskyDaniel G Remick

immunologyreceptorspharmacologymurine allergic-airway inflammationallergymyeloid cellsintermediate hostinflammation

Oxygen Carrying Nanoemulsions and Respiratory Hyperoxia Eliminate Tumor Hypoxia-Induced Suppression and Improve Cancer Immunotherapy. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Katarina Halpin-VeszeleiovaMichael MallouhAshley AproNuria RomeroCamille BahrMaureen ShinKelly WardLaura RosenbergMichail V. SitkovskyBruce SpiessStephen M. Hatfield

medicinenanomedicinecancer immunotherapyoncologyrespiratory hyperoxiatumor hypoxia-induced suppression

Comprehensive Genome Editing Confers ‘Off-The-Shelf’ Car-T Cells Superior Efficacy Against Solid Tumors. bioRxiv (Cold Spring Harbor Laboratory) (2023)

Targeting Hypoxia‐Adenosinergic Signaling to Enable Effective Anti‐Tumor Responses by Reprogramming the Immunosuppressive Tumor Microenvironment. The FASEB Journal (2022)

Kai BeattieNuria Roxana Romero NavarreteAnushka DongreMichail SitkovskyStephen Hatfield

Oxygen‐Generating Cryogels Restore T Cell Mediated Cytotoxicity in Hypoxic Tumors. Advanced Functional Materials (2021)

Thibault ColombaniLoek J. EggermontStephen M. HatfieldZachary J. RogersMahboobeh RezaeeyazdiAdnan MemicMichail V. SitkovskySidi A. Bencherif

Oxygen‐Generating Cryogels Restore T Cell Mediated Cytotoxicity in Hypoxic Tumors (Adv. Funct. Mater. 37/2021). Advanced Functional Materials (2021)

Thibault ColombaniLoek J. EggermontStephen M. HatfieldZachary J. RogersMahboobeh RezaeeyazdiAdnan MemicMichail V. SitkovskySidi A. Bencherif

Antihypoxic Oxygenation Agents With Respiratory Hyperoxia to Improve Cancer Immunotherapy. Journal of Clinical Investigation (2020)

Stephen M. HatfieldMichail V. Sitkovsky

Lessons From the A2A Adenosine Receptor Antagonist–Enabled Tumor Regression and Survival in Patients With Treatment-Refractory Renal Cell Cancer. Cancer Discovery (2020)

Michail V. Sitkovsky

Sufficient Numbers of Anti-Tumor T Cells is a Condition of Maximal Efficacy of Anti-Hypoxia-A2-Adenosinergic Drugs During Cancer Immunotherapy. Current Opinion in Pharmacology (2020)

Michail V Sitkovsky

pharmacologycancer immunotherapycancer treatmentmaximal efficacyimmunotherapy

Therapeutic Effects of Adenosine in High Flow 21% Oxygen Aereosol in Patients With Covid19-Pneumonia. PLoS ONE (2020)

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receptor tyrosine kinase

molecular cancer

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