Faculty

Institution

Unit

Venue

Enrique Rozengurt

University of California, Los Angeles

Affiliations

the College

Molecular Biology Institute (mbi)

NoneEnrique Rozengurt is currently serving as a Molecular Biology Institute (Mbi) faculty at University of California, Los Angeles.

Honors

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Experiences

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Education

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Enrique Rozengurt

University of California, Los Angeles

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cell biology pharmacology cell signaling signal transduction membrane biology biochemistry physiology medicinal research protein science gene expression cellular physiology tumor biology cancer biology cancer research cell regulation cell physiology oncology enzyme inhibition biological chemistry molecular physiology receptors pancreatic cancer redox biology dna synthesis mammalian biology signaling pathways biochemical sciences protein phosphorylation intestinal epithelial cells vascular biology liver physiology tissue physiology molecular regulation oncogenes cellular biology cancer growth insulin signaling g protein-coupled receptor cancer treatment molecular cell biology receptor (biochemistry) pathway analysis receptor tyrosine kinases cell proliferation phorbol esters cellular biochemistry cell growth thoracic oncology cell adhesion protein function tumor targeting anti-cancer agents applied physiology neuropeptides platelet-derived growth factor protein transport cancer genetics catalyst activation cell culture pancreatic cancer cells focal adhesion kinase toxinology mammalian physiology tyrosine phosphorylation gene regulation functional modification growth factors epidermal growth factor hla typing mitogenic response pasteurella multocida toxin quiescent cultures intact cells early events na-k pump activity clonal growth

Notable Scholarly Works

Notable Federal Grants

Collaborators

Stress and Obesity Signaling Converge on Creb Phosphorylation to Promote Pancreatic Cancer. Molecular Cancer Research (2024)

Xiaoying SunYaroslav TeperJames Sinnet-SmithMineh MarkarianO Joe HinesGang LiGuido EiblEnrique Rozengurt

signaling pathwayscancer researchcell signalingmolecular cancerpancreatic cancercreb phosphorylationobesitymolecular biologycancer biology

Upregulated Matrisomal Proteins and Extracellular Matrix Mechanosignaling Underlie Obesity-Associated Promotion of Pancreatic Ductal Adenocarcinoma. Cancers (2024)

Richard T. WaldronAurelia LugeaHui-Hua ChangHsin-Yuan SuCrystal QuirosMichael S. LewisMingtian CheV. Krishnan RamanujanEnrique RozengurtGuido EiblStephen J. Pandol

cancer geneticsextracellular matrixupregulated matrisomal proteinsdisease progressioncancer carevascular biologycancer genomicsobesitymatrix biologycancer biologydermatologycancer researchcancer growthtumor biologypancreatic ductal adenocarcinomapharmacologygeneticsoncologyoncogenescancer cells

Human Leukocyte Antigen Class I Antibody-Activated Endothelium Promotes Cd206+ M2 Macrophage Polarization and Mmp9 Secretion Through Tlr4 Signaling and P-Selectin in a Model of Antibody-Mediated Rejection and Allograft Vasculopathy. American Journal of Transplantation (2023)

Jessica Nevarez-MejiaYi-Ping JinHarry PickeringRajesh ParmarNicole M ValenzuelaRebecca A SosaSebastiaan HeidtGregory A FishbeinEnrique RozengurtM Baldwin WilliamRobert L FairchildElaine F Reed

immunologyreproductive immunologyliver transplantationgraft rejectionclinical immunologyhematologycellular immune responsesvascular biologyallograft vasculopathyvasculitisimmune responsescell transplantationinfectious diseasesimmunosuppressionantibody-mediated rejectionpathologyimmunotherapyinflammation

Lipophilic Statins Inhibit Yap Coactivator Transcriptional Activity in Hcc Cells Through Rho-Mediated Modulation of Actin Cytoskeleton. American Journal of Physiology-Gastrointestinal and Liver Physiology (2023)

Jihane N. BenhammouBo QiaoArthur KoJames Sinnett-SmithJoseph R. PisegnaEnrique Rozengurt

protein functioncell signalingliver physiologyproteinlipid interactionendocrinologytranslational physiologyhcc cellsprotein sciencemembrane biologycellular physiologytranscription (biology)rho-mediated modulationgastrointestinal pharmacologymolecular physiologyphysiologyimmunologyactin cytoskeletongene expressionpharmacologyenzyme inhibitionlipophilic statins

Lipophilic Statins Inhibit Yap Nuclear Localization, Coactivator Activity, and Migration in Response to Ligation of Hla Class I Molecules in Endothelial Cells: Role of Yap Multisite Phosphorylation. The Journal of Immunology (2023)

Tarique AnwarJames Sinnett-SmithYi-Ping JinElaine F. ReedEnrique Rozengurt

cell signalinginhibitory activitypathway analysisliver physiologybiochemistryantiviral researchcoactivator activityhematologyendocrinologyvascular biologyprotein transportimmune responsesprotein scienceinflammationmolecular immunologyimmunologyenzyme inhibitionpharmacologyclinical immunologyyap nuclear localizationendothelial cellslipophilic statins

Low Dosage Combination Treatment With Metformin and Simvastatin Inhibits Obesity-Promoted Pancreatic Cancer Development in Male Krasg12D Mice. Scientific Reports (2023)

Yaroslav TeperLinda YeRichard T. WaldronAurelia LugeaXiaoying SunJames Sinnett-SmithOscar J. HinesStephen J. PandolEnrique RozengurtGuido Eibl

dermatologypharmacologycancer researchpancreatic cancerobesityoncology

O24 Crosstalk Between Hla Class I and Tlr4 Mediates Pro-Inflammatory Signaling Cascades in Endothelial Cells via Tlr4/Myd88 Pathway. Human Immunology (2023)

Y. JinJ. Nevarez-MejiaA. TerryE.F. ReedE. Rozengurt

immunologysignaling pathwaysgene expressioninflammationcell signalinggeneticsmolecular immunologyendothelial cellssignal transductionpathway analysiscell biology

Statins Inhibit Protein Kinase D (Pkd) Activation in Intestinal Cells and Prevent Pkd1-Induced Growth of Murine Enteroids. AJP Cell Physiology (2023)

James Sinnett-SmithM. Eugenia Torres-MarquezJen-Kuan ChangYuki ShimizuFang HaoMartin G. MartinEnrique Rozengurt

cell signalingliver physiologyhost responsecell biologyintestinal cellselectrophysiologymurine enteroidscell physiologycellular biologymembrane biologyinflammationcellular physiologyanimal physiologytissue physiologymolecular physiologytumor biologyphysiologypharmacologycirculatory physiology

Supplemental Figure 1 From Insulin Receptor and Gpcr Crosstalk Stimulates Yap via Pi3K and Pkd in Pancreatic Cancer Cells. (2023)

Fang HaoQinhong XuYinglan ZhaoJan V. StevensSteven H. YoungJames Sinnett-SmithEnrique Rozengurt

immunologygene expressionpharmacologyinsulin signalinggpcr crosstalkcancer researchcell signalingpancreatic cancerinsulin receptorpancreatic cancer cellsmedicinal researchcancer biologytumor biologyneuroscience

Supplementary Figure 2 From Metformin Disrupts Crosstalk Between G Protein–Coupled Receptor and Insulin Receptor Signaling Systems and Inhibits Pancreatic Cancer Growth. (2023)

Krisztina KisfalviGuido EiblJames Sinnett-SmithEnrique Rozengurt

g protein-coupled receptorpharmacologypancreatic cancercell signalingmolecular pharmacologymolecular biologycancer biologycell biology

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Enrique Rozengurt

University of California, Los Angeles

Affiliations

the College

Molecular Biology Institute (mbi)

NoneEnrique Rozengurt is currently serving as a Molecular Biology Institute (Mbi) faculty at University of California, Los Angeles.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Enrique Rozengurt

University of California, Los Angeles

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Stress and Obesity Signaling Converge on Creb Phosphorylation to Promote Pancreatic Cancer. Molecular Cancer Research (2024)

Xiaoying SunYaroslav TeperJames Sinnet-SmithMineh MarkarianO Joe HinesGang LiGuido EiblEnrique Rozengurt

signaling pathwayscancer researchcell signalingmolecular cancerpancreatic cancercreb phosphorylationobesitymolecular biologycancer biology

Upregulated Matrisomal Proteins and Extracellular Matrix Mechanosignaling Underlie Obesity-Associated Promotion of Pancreatic Ductal Adenocarcinoma. Cancers (2024)

Richard T. WaldronAurelia LugeaHui-Hua ChangHsin-Yuan SuCrystal QuirosMichael S. LewisMingtian CheV. Krishnan RamanujanEnrique RozengurtGuido EiblStephen J. Pandol

Jessica Nevarez-MejiaYi-Ping JinHarry PickeringRajesh ParmarNicole M ValenzuelaRebecca A SosaSebastiaan HeidtGregory A FishbeinEnrique RozengurtM Baldwin WilliamRobert L FairchildElaine F Reed

Jihane N. BenhammouBo QiaoArthur KoJames Sinnett-SmithJoseph R. PisegnaEnrique Rozengurt

Tarique AnwarJames Sinnett-SmithYi-Ping JinElaine F. ReedEnrique Rozengurt

Low Dosage Combination Treatment With Metformin and Simvastatin Inhibits Obesity-Promoted Pancreatic Cancer Development in Male Krasg12D Mice. Scientific Reports (2023)

Yaroslav TeperLinda YeRichard T. WaldronAurelia LugeaXiaoying SunJames Sinnett-SmithOscar J. HinesStephen J. PandolEnrique RozengurtGuido Eibl

dermatologypharmacologycancer researchpancreatic cancerobesityoncology

O24 Crosstalk Between Hla Class I and Tlr4 Mediates Pro-Inflammatory Signaling Cascades in Endothelial Cells via Tlr4/Myd88 Pathway. Human Immunology (2023)

Y. JinJ. Nevarez-MejiaA. TerryE.F. ReedE. Rozengurt

immunologysignaling pathwaysgene expressioninflammationcell signalinggeneticsmolecular immunologyendothelial cellssignal transductionpathway analysiscell biology

Statins Inhibit Protein Kinase D (Pkd) Activation in Intestinal Cells and Prevent Pkd1-Induced Growth of Murine Enteroids. AJP Cell Physiology (2023)

James Sinnett-SmithM. Eugenia Torres-MarquezJen-Kuan ChangYuki ShimizuFang HaoMartin G. MartinEnrique Rozengurt

Supplemental Figure 1 From Insulin Receptor and Gpcr Crosstalk Stimulates Yap via Pi3K and Pkd in Pancreatic Cancer Cells. (2023)

Fang HaoQinhong XuYinglan ZhaoJan V. StevensSteven H. YoungJames Sinnett-SmithEnrique Rozengurt

Supplementary Figure 2 From Metformin Disrupts Crosstalk Between G Protein–Coupled Receptor and Insulin Receptor Signaling Systems and Inhibits Pancreatic Cancer Growth. (2023)

Krisztina KisfalviGuido EiblJames Sinnett-SmithEnrique Rozengurt

g protein-coupled receptorpharmacologypancreatic cancercell signalingmolecular pharmacologymolecular biologycancer biologycell biology

1
2
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5
59
10 / page

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