Faculty

Institution

Unit

Venue

Michael S. Krangel

George Barth Geller Distinguished Professor of Immunology Professor of Integrative Immunobiology

Duke University

Affiliations

Duke University School of Medicine

Immunology

Michael S. Krangel is currently serving as a Duke University School Of Medicine George Barth Geller Distinguished Professor of Immunology Professor of Integrative Immunobiology at Duke University.

Honors

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Experiences

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Education

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Michael S. Krangel

Duke University

George Barth Geller Distinguished Professor of Immunology Professor of Integrative Immunobiology

You can click a keyword to filter the displayed items

immunology genetics molecular biology cell biology gene expression immune responses gene regulation epigenetics human genetics experimental medicine receptors cell regulation experimental biology transcription regulation molecular immunology molecular regulation structural biology hla typing adaptive immune system molecular and cellular biology hematology protein science genome biology molecular cell biology medicinal research cellular biology immunochemistry histocompatibility chromosomal rearrangements cytogenetics mammalian biology gene function developmental regulation rna biology protein function receptor (biochemistry) protein expression cellular immune responses clinical immunology structural molecular biology biological chemistry protein assembly developmental immunology developmental genetics lymphocyte development t-cell receptor enhancer-blocking activity laboratory medicine liver physiology molecular science molecular physiology cellular physiology host response t-regulatory cell cytokines cancer genetics genetic diversity host factors gene regulatory networks cell control histone acetylation tcra repertoire glycosaminoglycan binding site comparative structural analysis allelic exclusion thymocyte development ccctc-binding factor stem cell research leukemia biochemical sciences hla-b antigens novel rearranging gene t-cell-receptor rearrangement thymocyte differentiation survival window alternative rna

Notable Scholarly Works

Notable Federal Grants

Collaborators

Organization and Rearrangement of Tcr Loci. Elsevier eBooks (2024)

Cristina Hernández-MunainMichael S. Krangel

genome editingtcr locichromosomal rearrangementsmolecular biologygenetics

RorγT Up-Regulates Rag Gene Expression in Dp Thymocytes to Expand the Tcra Repertoire. Science Immunology (2024)

Abani Kanta NaikDanielle J. DaupharsElizabeth CorbettLunden SimpsonDavid G. SchatzMichael S. Krangel

molecular immunologyimmunologyhost responsedermatologyimmune responsesgene functionadaptive immune systemdp thymocytesgene expressiongenetics

E Protein Binding at the Tcra Enhancer Promotes Tcra Repertoire Diversity. Frontiers in Immunology (2023)

Ariana MihaiSumedha RoyMichael S. KrangelYuan Zhuang

molecular immunologytcra enhancertcra repertoire diversityimmunologyimmune responsesmolecular biologyimmunochemistry

Methods for Study of Mouse T Cell Receptor α and β Gene Rearrangements. Methods in molecular biology (2022)

Danielle J. DaupharsGlendon WuCraig H. BassingMichael S. Krangel

receptorsimmunologymolecular biologygenetics

The Order and Logic of Cd4 Versus Cd8 Lineage Choice and Differentiation in Mouse Thymus. Nature Communications (2021)

Mohammad M. KarimiYa GuoXiaokai CuiHusayn A. PallikondaVeronika HorkováYi-Fang WangSara Ruiz GilGustavo Rodriguez-EstebanIrene Robles-RebolloLudovica BrunoRadina GeorgievaBhavik PatelJames ElliottMarian H. DoreDanielle DaupharsMichael S. KrangelBoris LenhardHolger HeynAmanda G. FisherOndřej ŠtěpánekMatthias Merkenschlager

animal sciencemouse thymuscellular differentiationimmunologyepigeneticsanimal biotechnologydevelopmental biologymammalian biologycell lineagehistocompatibilitygene expressiongene evolutiongenetics

Trav15-Dv6 Family Tcrd Rearrangements Diversify the Tcra Repertoire. The Journal of Experimental Medicine (2021)

Danielle J. DaupharsAriana MihaiLiuyang WangYuan ZhuangMichael S. Krangel

molecular diversityimmunologymolecular biologyexperimental medicinemolecular evolutiongenetics

A Role of the Ctcf Binding Site at Enhancer Eα in the Dynamic Chromatin Organization of the Tcra–Tcrd Locus. Nucleic Acids Research (2020)

Hao ZhaoZhaoqiang LiYongchang ZhuShasha BianYan ZhangLitao QinAbani Kanta NaikJiangtu HeZhenhai ZhangMichael S KrangelBingtao Hao

tcra–tcrd locustcra rearrangementchromatin remodelingcell biologygenome biologyctcf binding sitegene regulationmolecular cell biologynuclear organizationtranscription regulationchromatingene expressiongenetics

Rsss Set the Odds for Exclusion. The Journal of Experimental Medicine (2020)

Michael S. Krangel

public healthmedicineexperimental medicinesocial exclusionclinical researchstatistics

A Lamina-Associated Domain Border Governs Nuclear Lamina Interactions, Transcription, and Recombination of the Tcrb Locus. Cell Reports (2018)

Shiwei ChenTeresa Romeo LuperchioXianrong WongEurope B. DoanAaron T. ByrdKingshuk Roy ChoudhuryKaren L. ReddyMichael S. Krangel

cell physiologymolecular and cellular biologycell-matrix interactionsepigeneticscell biologygenome biologycellular physiologymembrane biologymolecular cell biologytranscription (biology)molecular biologycellular biologytcrb locuscell researchstructural molecular biologystructural biologygenetics

Diversification of the Tcr β Locus Vβ Repertoire by Ctcf. ImmunoHorizons (2018)

Shiwei ChenMichael S Krangel

genetic diversityimmunologygenomicspopulation geneticsgenetics

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Michael S. Krangel

George Barth Geller Distinguished Professor of Immunology Professor of Integrative Immunobiology

Duke University

Affiliations

Duke University School of Medicine

Immunology

Michael S. Krangel is currently serving as a Duke University School Of Medicine George Barth Geller Distinguished Professor of Immunology Professor of Integrative Immunobiology at Duke University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Michael S. Krangel

Duke University

George Barth Geller Distinguished Professor of Immunology Professor of Integrative Immunobiology

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Organization and Rearrangement of Tcr Loci. Elsevier eBooks (2024)

Cristina Hernández-MunainMichael S. Krangel

genome editingtcr locichromosomal rearrangementsmolecular biologygenetics

RorγT Up-Regulates Rag Gene Expression in Dp Thymocytes to Expand the Tcra Repertoire. Science Immunology (2024)

Abani Kanta NaikDanielle J. DaupharsElizabeth CorbettLunden SimpsonDavid G. SchatzMichael S. Krangel

molecular immunologyimmunologyhost responsedermatologyimmune responsesgene functionadaptive immune systemdp thymocytesgene expressiongenetics

E Protein Binding at the Tcra Enhancer Promotes Tcra Repertoire Diversity. Frontiers in Immunology (2023)

Ariana MihaiSumedha RoyMichael S. KrangelYuan Zhuang

molecular immunologytcra enhancertcra repertoire diversityimmunologyimmune responsesmolecular biologyimmunochemistry

Methods for Study of Mouse T Cell Receptor α and β Gene Rearrangements. Methods in molecular biology (2022)

Danielle J. DaupharsGlendon WuCraig H. BassingMichael S. Krangel

receptorsimmunologymolecular biologygenetics

The Order and Logic of Cd4 Versus Cd8 Lineage Choice and Differentiation in Mouse Thymus. Nature Communications (2021)

animal sciencemouse thymuscellular differentiationimmunologyepigeneticsanimal biotechnologydevelopmental biologymammalian biologycell lineagehistocompatibilitygene expressiongene evolutiongenetics

Trav15-Dv6 Family Tcrd Rearrangements Diversify the Tcra Repertoire. The Journal of Experimental Medicine (2021)

Danielle J. DaupharsAriana MihaiLiuyang WangYuan ZhuangMichael S. Krangel

molecular diversityimmunologymolecular biologyexperimental medicinemolecular evolutiongenetics

A Role of the Ctcf Binding Site at Enhancer Eα in the Dynamic Chromatin Organization of the Tcra–Tcrd Locus. Nucleic Acids Research (2020)

Hao ZhaoZhaoqiang LiYongchang ZhuShasha BianYan ZhangLitao QinAbani Kanta NaikJiangtu HeZhenhai ZhangMichael S KrangelBingtao Hao

Rsss Set the Odds for Exclusion. The Journal of Experimental Medicine (2020)

Michael S. Krangel

public healthmedicineexperimental medicinesocial exclusionclinical researchstatistics

A Lamina-Associated Domain Border Governs Nuclear Lamina Interactions, Transcription, and Recombination of the Tcrb Locus. Cell Reports (2018)

Shiwei ChenTeresa Romeo LuperchioXianrong WongEurope B. DoanAaron T. ByrdKingshuk Roy ChoudhuryKaren L. ReddyMichael S. Krangel

Diversification of the Tcr β Locus Vβ Repertoire by Ctcf. ImmunoHorizons (2018)

Shiwei ChenMichael S Krangel

genetic diversityimmunologygenomicspopulation geneticsgenetics

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Similar Faculty Members

David G. Schatz

Institution

Yale University

immunity (medicine)

genomics

Scott W. Hiebert

Institution

Vanderbilt University

nascent transcription

oncogene

Jenny Ting

Institution

University of North Carolina at Chapel Hill

gene discovery

innate immune system

Cornelis Murre

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University of California, San Diego

stem cell

haematopoiesis

Laurie Glimcher

Institution

Harvard University

immunology

genetics

Stephen D. Nimer

Institution

University of Miami

molecular biology

haematopoiesis

Ali Shilatifard

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Northwestern University

molecular biology

genetics

Dan R. Littman

Institution

New York University

immunology

epigenetics

Christophe Benoist

Institution

Harvard University

immunology

genetics

Blanck, George

Institution

University of South Florida

immunology

translational bioinformatics