Faculty

Institution

Unit

Venue

Michael Caplan

C N H Long Professor of Cellular And Molecular Physiology and Professor of Cell Biology

Yale University

Affiliations

Biological & Biomedical Sciences

Cell Biology

Cellular & Molecular Physiology

Michael Caplan is currently serving as a Biological & Biomedical Sciences C N H Long Professor of Cellular And Molecular Physiology and Professor of Cell Biology at Yale University.

Honors

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Experiences

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Education

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Michael Caplan

Yale University

C N H Long Professor of Cellular And Molecular Physiology and Professor of Cell Biology

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cell biology membrane biology molecular biology physiology pharmacology nephrology protein science signal transduction cell signaling enzymes gene expression molecular physiology structural biology cellular physiology protein transport renal function biological chemistry liver physiology vascular biology redox biology renal pathophysiology enzyme inhibition mammalian biology membrane transport cell physiology molecular sorting medicinal research molecular regulation neurophysiology intracellular trafficking cellular biology polarized epithelial cells cell trafficking animal physiology molecular cell biology circulatory physiology nanobiotechnology cell polarity structural molecular biology protein chemistry structure-function enzyme kinetics receptor tyrosine kinases neurochemistry epithelial cells polycystic kidney disease polarized cells respiratory medicine protein expression clinical immunology renal care cellular biochemistry cardiovascular physiology protein function translational physiology fragmentation effect biological inorganic chemistry gene regulation biomolecular interactions respiratory neurobiology amp-activated protein kinase functional expression ion pumps c-terminal tail human sciences cell interactions transcription regulation neurotransmission cell culture cell surface delivery plasma membrane tight junction components cation selectivity cystic fibrosis defects plga nanoparticles immunocytochemical localization epithelial tight junctions

Notable Scholarly Works

Notable Federal Grants

Collaborators

Physiologic Mechanisms Underlying Polycystic Kidney Disease. Physiological Reviews (2025)

Alessandra BolettaMichael J. Caplan

diabetesearly diagnosiscardiovascular diseasemolecular physiologycirculatory physiologyphysiologic mechanismscohort studiesneurologyepidemiologyprospective cohort studiesallostatic loadimmunologyvascular biologysurvival analysismedicinal researchhematologyendocrinologypolycystic kidney diseaseretrospective cohort studiescellular physiology

Polycystin-1 Acts as an Atypical Adhesion Gpcr That Responds to Novel Wnt Signaling and Mechanical Stimuli. bioRxiv (Cold Spring Harbor Laboratory) (2025)

Nikolay P. GreskoValeria PadovanoPeder M. BergAlbert C.M. OngStefan SomloNicole ScholzTobias LangenhanMichael J. Caplan

biophysicswnt signalingmechanical stimuliadhesioncell signalingmolecular biologycell adhesionatypical adhesion gpcr

Calcium Signalling and Transport in the Kidney. Nature Reviews Nephrology (2024)

Alexander StaruschenkoR. Todd AlexanderMichael J. CaplanDaria V. Ilatovskaya

urologymembrane transportcell signalingmembrane biologysignal transductionnephrologyneurologyrenal pathophysiologycalcium signalling

Calhm2 is a Mitochondrial Protein Import Channel That Regulates Fatty Acid Metabolism. Research Square (2024)

Elizabeth JonasNelli MnatsakanyanFelix Rivera-MolinaAndrew RobsonAlexandra MacColl GarfinkelAmrendra KumarStephen BatterValeria PadovanoKaitlin WebsterRebecca CardoneJustin BergDerek ToomreRichard Kibbey IVMichael CaplanMustafa Khokha

mitochondrial functionmetabolismmolecular metabolismfatty acid metabolismbiochemistrymolecular biologymetabolic regulation

EDITORIAL: Molecular Mechanisms Underlying Polycystic Kidney Disease: From the Smallest Bricks to the Big Scenario. Frontiers in Molecular Biosciences (2024)

Annarita Di MiseMichael J. CaplanGiovanna Valenti

big scenariogeneticsmolecular and cellular biologybiomolecular engineeringmolecular sciencemolecular mechanismspolycystic kidney diseasemolecular biophysicsstructural molecular biologybiological chemistrybiomolecular analysisstructural bioinformaticsmolecular engineeringnephrologymolecular biologymolecular researchmolecular medicinerenal function

High Resolution Reconstruction of the Proximal Tubule Apical Endocytic Pathway. Physiology (2024)

Emily LacknerRaj PandyaMariia BurdyniukC. Shan XuSong PangMichael CaplanOra Weisz

high resolution reconstructionendocytic pathwaycell biologyneurosciencehigh resolutionanimal physiologyhuman physiologyphysiologyneurophysiologycellular physiology

Identification of Early Transcriptional Markers of Autosomal Dominant Polycystic Kidney Disease Cystic Epithelial Cells. Physiology (2024)

Victoria RaiMario FailliMaurizio FiuscoAndrea Reyna-NeyraDiego di BernardoJoseph CraftMichael Caplan

cell biologyrna biologyanatomygene expressionmolecular physiologystem cell researchcirculatory physiologyhuman biologycytogeneticsgeneticsapplied physiologytranscription (biology)gene characterizationtranscription factorsphysiologyearly transcriptional markersorgan physiologygene functioncellular physiology

Identification of Polycystin 2 Missense Mutants Targeted for Endoplasmic Reticulum-Associated Degradation. AJP Cell Physiology (2024)

Christopher J. GuerrieroMarcelo D. CarattinoKatherine G. SharpLuke J. KantzNikolay P. GreskoMichael J. CaplanJeffrey L. Brodsky

cell physiologycell biologyendoplasmic reticulum-associated degradation

Incidence of Postsurgical Intraocular Inflammation 6 Months After Implantation With a Multifocal Intraocular Lens. Clinical Ophthalmology (2024)

James PaauwMichael CaplanMark GallardoKristi RushinJeffrey Horn

multifocal intraocular lensophthalmology

Scaleable Production of Highly Loaded Protein Nanoparticles for Immune Modulation. Communications Materials (2024)

Michael J. CaplanRichard BaldwinXiangyun YinAlexander GrishinStephanie EisenbarthHugh A. SampsonKim BottomlyRobert K. Prud’homme

nanoparticlesmaterials scienceimmune modulationprotein nanoparticlesnanotechnologyscaleable production

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Michael Caplan

C N H Long Professor of Cellular And Molecular Physiology and Professor of Cell Biology

Yale University

Affiliations

Biological & Biomedical Sciences

Cell Biology

Cellular & Molecular Physiology

Michael Caplan is currently serving as a Biological & Biomedical Sciences C N H Long Professor of Cellular And Molecular Physiology and Professor of Cell Biology at Yale University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Michael Caplan

Yale University

C N H Long Professor of Cellular And Molecular Physiology and Professor of Cell Biology

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Physiologic Mechanisms Underlying Polycystic Kidney Disease. Physiological Reviews (2025)

Alessandra BolettaMichael J. Caplan

Polycystin-1 Acts as an Atypical Adhesion Gpcr That Responds to Novel Wnt Signaling and Mechanical Stimuli. bioRxiv (Cold Spring Harbor Laboratory) (2025)

Nikolay P. GreskoValeria PadovanoPeder M. BergAlbert C.M. OngStefan SomloNicole ScholzTobias LangenhanMichael J. Caplan

biophysicswnt signalingmechanical stimuliadhesioncell signalingmolecular biologycell adhesionatypical adhesion gpcr

Calcium Signalling and Transport in the Kidney. Nature Reviews Nephrology (2024)

Alexander StaruschenkoR. Todd AlexanderMichael J. CaplanDaria V. Ilatovskaya

urologymembrane transportcell signalingmembrane biologysignal transductionnephrologyneurologyrenal pathophysiologycalcium signalling

Calhm2 is a Mitochondrial Protein Import Channel That Regulates Fatty Acid Metabolism. Research Square (2024)

mitochondrial functionmetabolismmolecular metabolismfatty acid metabolismbiochemistrymolecular biologymetabolic regulation

EDITORIAL: Molecular Mechanisms Underlying Polycystic Kidney Disease: From the Smallest Bricks to the Big Scenario. Frontiers in Molecular Biosciences (2024)

Annarita Di MiseMichael J. CaplanGiovanna Valenti

High Resolution Reconstruction of the Proximal Tubule Apical Endocytic Pathway. Physiology (2024)

Emily LacknerRaj PandyaMariia BurdyniukC. Shan XuSong PangMichael CaplanOra Weisz

high resolution reconstructionendocytic pathwaycell biologyneurosciencehigh resolutionanimal physiologyhuman physiologyphysiologyneurophysiologycellular physiology

Identification of Early Transcriptional Markers of Autosomal Dominant Polycystic Kidney Disease Cystic Epithelial Cells. Physiology (2024)

Victoria RaiMario FailliMaurizio FiuscoAndrea Reyna-NeyraDiego di BernardoJoseph CraftMichael Caplan

Identification of Polycystin 2 Missense Mutants Targeted for Endoplasmic Reticulum-Associated Degradation. AJP Cell Physiology (2024)

Christopher J. GuerrieroMarcelo D. CarattinoKatherine G. SharpLuke J. KantzNikolay P. GreskoMichael J. CaplanJeffrey L. Brodsky

cell physiologycell biologyendoplasmic reticulum-associated degradation

Incidence of Postsurgical Intraocular Inflammation 6 Months After Implantation With a Multifocal Intraocular Lens. Clinical Ophthalmology (2024)

James PaauwMichael CaplanMark GallardoKristi RushinJeffrey Horn

multifocal intraocular lensophthalmology

Scaleable Production of Highly Loaded Protein Nanoparticles for Immune Modulation. Communications Materials (2024)

Michael J. CaplanRichard BaldwinXiangyun YinAlexander GrishinStephanie EisenbarthHugh A. SampsonKim BottomlyRobert K. Prud’homme

nanoparticlesmaterials scienceimmune modulationprotein nanoparticlesnanotechnologyscaleable production

1
2
3
4
5
22
10 / page

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