Faculty

Institution

Unit

Venue

William Guggino

Professor

Johns Hopkins University

Affiliations

School of Medicine

Physiology

William Guggino is currently serving as a Physiology Professor at Johns Hopkins University.

Honors

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Experiences

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Education

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William Guggino

Johns Hopkins University

Professor

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membrane biology cell biology physiology genetics molecular biology cellular physiology cystic fibrosis gene expression nephrology molecular physiology protein science cell signaling renal function cell physiology gene therapy signal transduction biological chemistry mammalian biology vascular biology structural biology membrane transport molecular regulation liver physiology protein transport respiratory medicine applied physiology medicinal research renal pathophysiology avian biology redox biology cellular biochemistry animal physiology molecular cell biology gene transfer gene delivery tissue physiology cellular biology mammalian physiology kidney research biomolecular interactions clinical physiology protein expression gene vector gene regulation intracellular trafficking protein function cell regulation chloride channels physiological research human physiology viral genetics circulatory physiology receptor (biochemistry) cell trafficking osmoregulation rna biology transcription regulation integrative biology adeno-associated virus epithelial cells polycystic kidney disease early distal tubule gene function neurochemistry molecular neurobiology chloride channel amphiuma kidney rhesus macaques cftr expression ion transport volume regulation xenopus oocytes aquaporin cdna aquaporin chip water channel molecular cloning

Notable Scholarly Works

Notable Federal Grants

Collaborators

The Ion Channel, Cftr, Assembles With Hippo Pathway Proteins Taz and Yap in Polycystic Kidney Disease. Journal of Biological Chemistry (2026)

molecular and cellular biologyprotein sciencemembrane transportcell signalingcell biologycellular physiologyprotein functionbiochemistrybiological functionmolecular physiologymolecular cell biologymolecular biologybiological chemistrysignal transductioncellular biochemistry

A Novel Gene Therapy for Arpkd Based on Cftr. American Journal of Physiology-Gastrointestinal and Liver Physiology (2025)

gene therapyliver physiologyliver diseasemolecular physiologypharmacology

279 Adeno-Associated Virus-1 or 6-Δ27-264 Cftr Successfully Ameliorated Clinical Symptoms in G551D Ferrets. Journal of Cystic Fibrosis (2024)

L. CebotaruC. CiobanuW. Guggino

vaccinesimmunologyvascular biologyinfectious diseasescystic fibrosisvirus-host interactionsneurovirologyclinical symptomscytopathologygeneral virologyviral pathogenesisvirologymicrobiologymolecular diagnosticsvirus researchdiagnosisantiviral researchmolecular virologyvirus structure

Amelioration of Airway and Gi Disease in G551D-Cf Ferrets by Aav1 and Aav6. Gene Therapy (2024)

Cristian CiobanuMurali YandaAdi ZeidanJessica IzziWilliam B. GugginoLiudmila Cebotaru

pathologyvaccinesstem cell researchdisease progressiondevelopmental biologytherapeutic targetsvascular biologygut-organ axistumor biologyimmunotherapydna repaironcogenesrenal functioncellular therapybone homeostasiscartilageneurologygi diseasebone disease

Cftr and Pc2, Partners in the Primary Cilia in Autosomal Dominant Polycystic Kidney Disease. American Journal of Physiology-Cell Physiology (2023)

Murali K. YandaCristian CiobanuWilliam B. GugginoLiudmila Cebotaru

cell physiologyphysiologycellular physiologytissue physiologyprimary ciliamembrane biologyurologygenetics

Transduction of Ferret Surface and Basal Cells of Airways, Lung, Liver, and Pancreas via Intratracheal or Intravenous Delivery of Adeno-Associated Virus 1 or 6. Human Gene Therapy (2023)

Murali K. YandaAdi ZeidanCristian CiobanuJessica IzziWilliam B. GugginoLiudmila Cebotaru

gene therapygene deliveryviral geneticsvirologyvirus-host interactionscell biologyferret surfacemedicinevirus transmissionveterinary medicinehuman geneticsgene expressiongene transferbasal cellsgenetics

Megalin-Mediated Albumin Endocytosis in Renal Proximal Tubules is Involved in the Antiproteinuric Effect of Angiotensin II Type 1 Receptor Blocker in a Subclinical Acute Kidney Injury Animal Model. Biochimica et Biophysica Acta (BBA) - General Subjects (2021)

Diogo B PeruchettiPaulo F R Barahuna-FilhoRodrigo P Silva-AguiarThiago P AbreuChristina M TakiyaJie ChengAna Acacia S PinheiroLiudmila CebotaruWilliam B GugginoCelso Caruso-Neves

biomimetic systemsmegalin-mediated albumin endocytosisreceptor blockerpharmacologybiomechanicsvascular biologynephrologyphysiologyhematologyapplied physiologyreceptorsrenal functionreceptor tyrosine kinasesantiproteinuric effectmedicinal researchbioenergeticsrenal pathophysiologyacute kidney injurybiophysicsanimal scienceinflammationrenal proximal tubules

Short-Term Steroid Treatment of Rhesus Macaque Increases Transduction. Human Gene Therapy (2021)

Murali K. YandaVartika TomarCristina Valeria CebotaruWilliam B. GugginoLiudmila Cebotaru

gene therapyanimal biotechnologyneurosciencemedicineshort-term steroid treatmentmammalian biologygenetics

The Mitochondrial Ca2+ Import Complex is Altered in Adpkd. Cell Calcium (2021)

Murali K YandaVartika TomarRobert ColeWilliam B. GugginoLiudmila Cebotaru

cell biologymembrane biologymolecular biologymitochondrial functionredox biologygenetics

Future Directions in Early Cystic Fibrosis Lung Disease Research: An Nhlbi Workshop Report. UNC Libraries (2020)

Ramsey, Bonnie W.Banks-Schlegel, SusanAccurso, Frank J.Boucher, Richard C.Cutting, Garry R.Engelhardt, John F.Guggino, William B.Karp, Christopher L.Knowles, Michael R.Kolls, Jay K.LiPuma, John J.Lynch, SusanMcCray, Paul B.Rubenstein, Ronald C.Singh, Pradeep K.Sorscher, EricWelsh, Michael

cystic fibrosisimmunologyrespiratory medicineglobal healthfuture directionshealth sciences

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William Guggino

Professor

Johns Hopkins University

Affiliations

School of Medicine

Physiology

William Guggino is currently serving as a Physiology Professor at Johns Hopkins University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

William Guggino

Johns Hopkins University

Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

The Ion Channel, Cftr, Assembles With Hippo Pathway Proteins Taz and Yap in Polycystic Kidney Disease. Journal of Biological Chemistry (2026)

A Novel Gene Therapy for Arpkd Based on Cftr. American Journal of Physiology-Gastrointestinal and Liver Physiology (2025)

gene therapyliver physiologyliver diseasemolecular physiologypharmacology

279 Adeno-Associated Virus-1 or 6-Δ27-264 Cftr Successfully Ameliorated Clinical Symptoms in G551D Ferrets. Journal of Cystic Fibrosis (2024)

L. CebotaruC. CiobanuW. Guggino

Amelioration of Airway and Gi Disease in G551D-Cf Ferrets by Aav1 and Aav6. Gene Therapy (2024)

Cristian CiobanuMurali YandaAdi ZeidanJessica IzziWilliam B. GugginoLiudmila Cebotaru

Cftr and Pc2, Partners in the Primary Cilia in Autosomal Dominant Polycystic Kidney Disease. American Journal of Physiology-Cell Physiology (2023)

Murali K. YandaCristian CiobanuWilliam B. GugginoLiudmila Cebotaru

cell physiologyphysiologycellular physiologytissue physiologyprimary ciliamembrane biologyurologygenetics

Transduction of Ferret Surface and Basal Cells of Airways, Lung, Liver, and Pancreas via Intratracheal or Intravenous Delivery of Adeno-Associated Virus 1 or 6. Human Gene Therapy (2023)

Murali K. YandaAdi ZeidanCristian CiobanuJessica IzziWilliam B. GugginoLiudmila Cebotaru

Diogo B PeruchettiPaulo F R Barahuna-FilhoRodrigo P Silva-AguiarThiago P AbreuChristina M TakiyaJie ChengAna Acacia S PinheiroLiudmila CebotaruWilliam B GugginoCelso Caruso-Neves

Short-Term Steroid Treatment of Rhesus Macaque Increases Transduction. Human Gene Therapy (2021)

Murali K. YandaVartika TomarCristina Valeria CebotaruWilliam B. GugginoLiudmila Cebotaru

gene therapyanimal biotechnologyneurosciencemedicineshort-term steroid treatmentmammalian biologygenetics

The Mitochondrial Ca2+ Import Complex is Altered in Adpkd. Cell Calcium (2021)

Murali K YandaVartika TomarRobert ColeWilliam B. GugginoLiudmila Cebotaru

cell biologymembrane biologymolecular biologymitochondrial functionredox biologygenetics

Future Directions in Early Cystic Fibrosis Lung Disease Research: An Nhlbi Workshop Report. UNC Libraries (2020)

cystic fibrosisimmunologyrespiratory medicineglobal healthfuture directionshealth sciences

1
2
3
4
5
30
10 / page