Faculty

Institution

Unit

Venue

Melissa Stuchell-Brereton

Research Instructor

Washington University in St. Louis

Affiliations

School of Medicine

Department of Biochemistry and Molecular Biophysics

Melissa Stuchell-brereton is currently serving as a Biochemistry And Molecular Biophysics Research Instructor at Washington University In St. Louis.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Melissa Stuchell-Brereton

Washington University in St. Louis

Research Instructor

You can click a keyword to filter the displayed items

molecular biology biophysics protein structure structural biology protein science structural molecular biology sars-cov-2 cell biology biomolecular structure virus research virus structure biophysical chemistry single molecules neuroscience virology nucleic acids molecular cell biology rna biology conformational studies viral structural protein single molecule biophysics single-molecule detection hiv membrane biology membrane proteins general virology biological chemistry antiviral research molecular neurodegeneration viral genetics molecular recognition protein assembly proteinlipid interaction biophysical modeling protein misfolding degenerative pathology mitotic spindle positioning phase separates functional insights biophysical study condensed matter molecular science clinical lipidology molecular structure structural chemistry biological macromolecules viral evolution protein transport cell motility non-coding rna phase separation molecular biological method yeast lipoprotein metabolism biophysical aspect structural dynamics biomolecular interactions nucleic acid chemistry experimental biophysics biomolecular structure prediction viral replication protein modeling hiv budding protein network escrt-iii recognition escrt-iii protein interactions mit domain polarized cell lipid-bound forms intermediate chain functional interaction dynein light chain disordered n-terminal tail crowded solutions molecular biophysics molecular characterization biochemistry

Notable Scholarly Works

Notable Federal Grants

Collaborators

Bps2025 - Structural Dynamics of the Intrinsically Disordered Linker Region of Cardiac Troponin T. Biophysical Journal (2025)

biophysicsbiophysical aspectprotein structurecardiac troponin tprotein sciencebiomolecular structuredisordered linker regionstructural dynamicsmolecular biophysicsmolecular biologybiophysical modelingprotein foldingstructural molecular biologystructural biology

Bps2025 - the Impact of Single-Residue Mutations on Contractility and Intermolecular Interactions of the Intrinsically Disordered Linker of Cardiac Troponin-T. Biophysical Journal (2025)

biophysicsprotein structuremutagenesis (molecular biology technique)protein sciencedisordered linkerbiomolecular structuremolecular biophysicscardiac troponin-tmolecular biologybiophysical modelingprotein foldingbiomolecular interactionsbiophysical chemistrysingle-residue mutations

Bps2025 - Using Single Molecule Spectroscopy to Probe Nucleocapsid-Rna Interactions. Biophysical Journal (2025)

single-molecule detectionnucleic acidsbiochemistrymolecular biophysicstranscription (biology)molecular biologynucleic acid chemistrysingle moleculessingle molecule spectroscopysingle molecule biophysicsstructural molecular biologystructural biology

The Dimerization Domain of Sars-Cov-2 Nucleocapsid Protein is Partially Disordered and Forms a Dynamic High-Affinity Dimer. Cell Reports Physical Science (2025)

dimerization domaindynamic high-affinity dimerprotein sciencebiomolecular structureprotein assemblysars-cov-2antiviral researchsars-cov-2 nucleocapsid proteinmolecular biologyprotein structurebiomolecular engineeringvirus structurestructural molecular biologystructural biologyviral structural protein

Accounting for Fast vs Slow Exchange in Single Molecule Fret Experiments Reveals Hidden Conformational States. Journal of Chemical Theory and Computation (2024)

Justin J. MillerUpasana L. MallimadugulaMaxwell I. ZimmermanMelissa D. Stuchell-BreretonAndrea SorannoGregory R. Bowman

biophysicscondensed matterneuroscienceconformational statessingle moleculescondensed matter physicsmaterials science

Impact of Crowding on Conformations and Interactions of the Sars-Cov-2 Nucleocapsid Protein and Rna. Biophysical Journal (2024)

Madison StringerJasmine CubukJeremias InciccoDebjit RoyKathleen B. HallMelissa D. Stuchell-BreretonAndrea Soranno

biophysicssars-cov-2virus structurevirus research

Single-Molecule Spectroscopy of the Sars-Cov-2 Nucleocapsid Protein. Biophysical Journal (2024)

Jasmine CubukJ. Jeremias InciccoMelissa D. Stuchell-BreretonKathleen B. HallAndrea Soranno

biophysicssars-cov-2single moleculessingle-molecule spectroscopy

Structural Dynamics of the Intrinsically Disordered Linker Region of Cardiac Troponin T. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Jasmine CubukLina GreenbergAkiva E. GreenbergRyan J. EmeneckerMelissa D. Stuchell-BreretonAlex S. HolehouseAndrea SorannoMichael J. Greenberg

biophysicsprotein sciencecell biologydisordered linker regionmolecular biologyprotein structurestructural biology

The Dimerization Domain of Sars Cov 2 Nucleocapsid Protein is Partially Disordered as a Monomer and Forms a High Affinity Dynamic Complex.. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Jasmine CubukJ Jeremias InciccoKathleen B HallAlex S HolehouseMelissa D Stuchell-BreretonAndrea Soranno

dimerization domainnucleocapsid proteinsars-cov-2molecular biologyprotein structurevirus structuregeneticsvirus research

Apolipoprotein E4 Has Extensive Conformational Heterogeneity in Lipid-Free and Lipid-Bound Forms. Proceedings of the National Academy of Sciences (2023)

Melissa D. Stuchell-BreretonMaxwell I. ZimmermanJustin J. MillerUpasana L. MallimadugulaJ. Jeremías InciccoDebjit RoyLouis G. SmithJasmine CubukBerevan BabanGregory T. DeKosterCarl FriedenGregory R. BowmanAndrea Soranno

neurologyproteomicsconformational studiesprotein scienceepigeneticsneurosciencemembrane biologymolecular biologyprotein structurelipid-bound formsstructural biology

1
2
3
4
10 / page

Melissa Stuchell-Brereton

Research Instructor

Washington University in St. Louis

Affiliations

School of Medicine

Department of Biochemistry and Molecular Biophysics

Melissa Stuchell-brereton is currently serving as a Biochemistry And Molecular Biophysics Research Instructor at Washington University In St. Louis.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Melissa Stuchell-Brereton

Washington University in St. Louis

Research Instructor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Bps2025 - Structural Dynamics of the Intrinsically Disordered Linker Region of Cardiac Troponin T. Biophysical Journal (2025)

Bps2025 - the Impact of Single-Residue Mutations on Contractility and Intermolecular Interactions of the Intrinsically Disordered Linker of Cardiac Troponin-T. Biophysical Journal (2025)

Bps2025 - Using Single Molecule Spectroscopy to Probe Nucleocapsid-Rna Interactions. Biophysical Journal (2025)

The Dimerization Domain of Sars-Cov-2 Nucleocapsid Protein is Partially Disordered and Forms a Dynamic High-Affinity Dimer. Cell Reports Physical Science (2025)

Accounting for Fast vs Slow Exchange in Single Molecule Fret Experiments Reveals Hidden Conformational States. Journal of Chemical Theory and Computation (2024)

Justin J. MillerUpasana L. MallimadugulaMaxwell I. ZimmermanMelissa D. Stuchell-BreretonAndrea SorannoGregory R. Bowman

biophysicscondensed matterneuroscienceconformational statessingle moleculescondensed matter physicsmaterials science

Impact of Crowding on Conformations and Interactions of the Sars-Cov-2 Nucleocapsid Protein and Rna. Biophysical Journal (2024)

Madison StringerJasmine CubukJeremias InciccoDebjit RoyKathleen B. HallMelissa D. Stuchell-BreretonAndrea Soranno

biophysicssars-cov-2virus structurevirus research

Single-Molecule Spectroscopy of the Sars-Cov-2 Nucleocapsid Protein. Biophysical Journal (2024)

Jasmine CubukJ. Jeremias InciccoMelissa D. Stuchell-BreretonKathleen B. HallAndrea Soranno

biophysicssars-cov-2single moleculessingle-molecule spectroscopy

Structural Dynamics of the Intrinsically Disordered Linker Region of Cardiac Troponin T. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Jasmine CubukLina GreenbergAkiva E. GreenbergRyan J. EmeneckerMelissa D. Stuchell-BreretonAlex S. HolehouseAndrea SorannoMichael J. Greenberg

biophysicsprotein sciencecell biologydisordered linker regionmolecular biologyprotein structurestructural biology

The Dimerization Domain of Sars Cov 2 Nucleocapsid Protein is Partially Disordered as a Monomer and Forms a High Affinity Dynamic Complex.. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Jasmine CubukJ Jeremias InciccoKathleen B HallAlex S HolehouseMelissa D Stuchell-BreretonAndrea Soranno

dimerization domainnucleocapsid proteinsars-cov-2molecular biologyprotein structurevirus structuregeneticsvirus research

Apolipoprotein E4 Has Extensive Conformational Heterogeneity in Lipid-Free and Lipid-Bound Forms. Proceedings of the National Academy of Sciences (2023)

neurologyproteomicsconformational studiesprotein scienceepigeneticsneurosciencemembrane biologymolecular biologyprotein structurelipid-bound formsstructural biology

1
2
3
4
10 / page

Similar Faculty Members

Andrea Soranno

Institution

Washington University in St. Louis

membraneless organelles

single-molecule fluorescence spectroscopy

Kathleen Hall

Institution

Washington University in St. Louis

rna structure prediction

molecular biology

Alex Holehouse

Institution

Washington University in St. Louis

self-assembly

protein phase separation

Elisar J. Barbar

Institution

Oregon State University

molecular biology

nuclear magnetic resonance spectroscopy

Katsuhiko Murakami

Institution

Pennsylvania State University

molecular informatics

structural biology

Mahmoud Moradi

Institution

University of Arkansas

computational molecular biophysics

nonequilibrium statistical mechanics

Chunyu Wang

Institution

Rensselaer Polytechnic Institute

drug target

cancer research

Penny Beuning

Institution

Northeastern University

molecular biology

biotechnology advance

Catherine Royer

Institution

Rensselaer Polytechnic Institute

transcription regulation

protein science

Elliot L. Elson

Institution

Washington University in St. Louis

photomedicine

biomolecular engineering

Similar Faculty Members

Andrea Soranno

Institution

Washington University in St. Louis

membraneless organelles

single-molecule fluorescence spectroscopy

Kathleen Hall

Institution

Washington University in St. Louis

rna structure prediction

molecular biology

Alex Holehouse

Institution

Washington University in St. Louis

self-assembly

protein phase separation

Elisar J. Barbar

Institution

Oregon State University

molecular biology

nuclear magnetic resonance spectroscopy

Katsuhiko Murakami

Institution

Pennsylvania State University

molecular informatics

structural biology

Mahmoud Moradi

Institution

University of Arkansas

computational molecular biophysics

nonequilibrium statistical mechanics

Chunyu Wang

Institution

Rensselaer Polytechnic Institute

drug target

cancer research

Penny Beuning

Institution

Northeastern University

molecular biology

biotechnology advance

Catherine Royer

Institution

Rensselaer Polytechnic Institute

transcription regulation

protein science

Elliot L. Elson

Institution

Washington University in St. Louis

photomedicine

biomolecular engineering