Faculty

Institution

Unit

Venue

Melanie J. Scott

Associate Professor

University of Pittsburgh

Affiliations

Medicine

Interdisciplinary Biomedical Graduate Program

Surgery

Melanie J. Scott is currently serving as an Interdisciplinary Biomedical Graduate Program Associate Professor at University of Pittsburgh.

Honors

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Experiences

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Education

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Melanie J. Scott

University of Pittsburgh

Associate Professor

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immunology hematology inflammation immune responses pharmacology cell biology medicine hepatology liver physiology cell signaling sepsis medicinal research clinical immunology signal transduction respiratory medicine gene expression vascular biology cell death mammalian biology clinical microbiology innate immune system cellular immune responses autophagy adaptive immune system traumatology surgical care hemostasis hemorrhagic shock signaling pathways chronic inflammation cell regulation cellular physiology experimental medicine intensive care cytokines apoptosis liver disease general surgery cellular therapy biological chemistry pathway analysis inflammatory markers inflammatory diseases medical microbiology immunopathology mitochondrial function redox signaling systemic inflammation laboratory medicine clinical biochemistry applied microbiology anti-inflammatory tissue injury histocompatibility renal function ischemic syndrome immunosuppression trauma surgery natural killer cells inflammasome activation organ damage dendritic cells insulin signaling host specificity cellular biology bacterial clearance high mobility group lung endothelial cells tissue damage tumor necrosis factor genetic background bone marrow bacterial peritonitis organ injury immune mediators macrophage endocytosis infectious diseases host response free radical biology sickle cell disease innate immune responses

Notable Scholarly Works

Notable Federal Grants

Collaborators

CORRECTION: Caspase 1 Activation is Protective Against Hepatocyte Cell Death by Up-Regulating Beclin 1 Protein and Mitochondrial Autophagy in the Setting of Redox Stress. Journal of Biological Chemistry (2024)

Qian SunWentao GaoPatricia LoughranRick ShapiroJie FanTimothy R. BilliarMelanie J. Scott

cell deathmitochondrial autophagyredox signalingfree radical biologyredox biologyhepatocyte cell deathmolecular biologybiological chemistryredox stressautophagysignal transductionoxidative stressbiochemistrycell biology

Irg1/Acod1 Promotes Neutrophil Reverse Migration and Alleviates Local Inflammation. Journal of Leukocyte Biology (2024)

Jingjing JiHanhui ZhongYuehua LiTimothy R BilliarMark A WilsonMelanie J ScottJie Fan

immunologyneutrophil reverse migrationhematologyinnate immune systemlocal inflammationimmune responsescell biologygranulocyteinflammation

Mechanism of Lactic Acidemia-Promoted Pulmonary Endothelial Cells Death in Sepsis: Role for Cirp-Zbp1-Panoptosis Pathway. Military Medical Research (2024)

Ting GongQing-De WangPatricia A. LoughranYue-Hua LiMelanie J. ScottTimothy R. BilliarYou-Tan LiuJie Fan

pulmonary arterial hypertensionmedicinecell deathpulmonary circulationnephrologyvascular biologypulmonary vascular diseaseendothelial dysfunctionclinical researchimmune responsesanesthesiologyinfectious diseasesrespiratory medicinesepsisintensive careoxidative stressliver physiologyhemostasis

Macrophage Switching: Polarization and Mobilization After Trauma. Shock (2023)

Lara HoteitPatricia LoughranShannon HaldemanDanielle ReiserNijmeh AlsaadiElizabeth AndraskaJillian BonarotiAmudan SrinivasanKelly M. WilliamsonJurgis AlvikasRichard SteinmanJoshua KeeganJames A. LedererMelanie ScottMatthew D. NealAnupamaa Seshadri

immunologypublic healthmacrophage switchingemergency medicinetrauma

Reinvigorating the Jlb Experience. Journal of Leukocyte Biology (2023)

Michael SchnoorMelanie J ScottLuis J Montaner

immunologyphysiologyrehabilitationhematologyregenerative medicinelived experienceimmune responses

The Role of Gasdermin-D-Mediated Pyroptosis in Organ Injury and Its Therapeutic Implications. Organogenesis (2023)

Joud MullaRohan KattiMelanie J. Scott

organ injurypharmacologygasdermin-d-mediated pyroptosistherapeutic implicationsinflammation

Caspase-11 Contributes to Trauma-Induced Coagulopathy in a Murine Polytrauma Model. Journal of the American College of Surgeons (2022)

Nijmeh AlsaadiJoud MullaZachary SecundaBashar Al MatourSultan AbdelhamidMelanie J Scott

surgeryemergency medicinetrauma-induced coagulopathytraumamurine polytrauma modelpolytraumacoagulopathycritical careresuscitation

Effect of Irrigation Fluid Composition on Hemostasis in Mouse Bleeding Models. Shock (2022)

Nijmeh AlsaadiAdnan HassouneShannon HaldemanKelly M. WilliamsonWilliam PlautzLara HoteitJurgis AlvikasElizabeth A. AndraskaAmudan J. SrinivasanJillian BonarotiAnupamaa SeshadriRoberto Mota-AlvidrezMelanie J. ScottPaul A. GardnerCarl H. SnydermanMatthew D. Neal

neurologydermatologyliver physiologydisease progressionhematologyvascular biologymammalian biologyirrigation fluid compositionrespiratory medicinemouse bleeding modelslivestock sciencehealth scienceshemostasis

Experimental Fibrosis Alters Matrix-Bound Vesicles Cargo That Do Not Revert After Histologic Recovery. Journal of Hepatology (2022)

Toshifumi SatoBashar MatourJiang LiMichael MerchantDaniel WilkeyKenichi IkejimaStephen BadylakGeorge HusseyMelanie ScottGavin Arteel

dermatologyfibrosishematologyregenerative medicineexperimental medicinematrix biologyhistologic recoveryhepatologyhealth sciencescell biology

Grk2 Regulates Group 2 Innate Lymphoid Cell Mobilization in Sepsis. Molecular Medicine (2022)

Dengming LaiWeiwei ChenKai ZhangMelanie J. ScottYuehua LiTimothy R. BilliarMark A. WilsonJie Fan

immunologymedicineemergency medicineinnate immune systemsepsiscell regulationmolecular medicine

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Melanie J. Scott

Associate Professor

University of Pittsburgh

Affiliations

Medicine

Interdisciplinary Biomedical Graduate Program

Surgery

Melanie J. Scott is currently serving as an Interdisciplinary Biomedical Graduate Program Associate Professor at University of Pittsburgh.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Melanie J. Scott

University of Pittsburgh

Associate Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Qian SunWentao GaoPatricia LoughranRick ShapiroJie FanTimothy R. BilliarMelanie J. Scott

Irg1/Acod1 Promotes Neutrophil Reverse Migration and Alleviates Local Inflammation. Journal of Leukocyte Biology (2024)

Jingjing JiHanhui ZhongYuehua LiTimothy R BilliarMark A WilsonMelanie J ScottJie Fan

immunologyneutrophil reverse migrationhematologyinnate immune systemlocal inflammationimmune responsescell biologygranulocyteinflammation

Mechanism of Lactic Acidemia-Promoted Pulmonary Endothelial Cells Death in Sepsis: Role for Cirp-Zbp1-Panoptosis Pathway. Military Medical Research (2024)

Ting GongQing-De WangPatricia A. LoughranYue-Hua LiMelanie J. ScottTimothy R. BilliarYou-Tan LiuJie Fan

Macrophage Switching: Polarization and Mobilization After Trauma. Shock (2023)

immunologypublic healthmacrophage switchingemergency medicinetrauma

Reinvigorating the Jlb Experience. Journal of Leukocyte Biology (2023)

Michael SchnoorMelanie J ScottLuis J Montaner

immunologyphysiologyrehabilitationhematologyregenerative medicinelived experienceimmune responses

The Role of Gasdermin-D-Mediated Pyroptosis in Organ Injury and Its Therapeutic Implications. Organogenesis (2023)

Joud MullaRohan KattiMelanie J. Scott

organ injurypharmacologygasdermin-d-mediated pyroptosistherapeutic implicationsinflammation

Caspase-11 Contributes to Trauma-Induced Coagulopathy in a Murine Polytrauma Model. Journal of the American College of Surgeons (2022)

Nijmeh AlsaadiJoud MullaZachary SecundaBashar Al MatourSultan AbdelhamidMelanie J Scott

surgeryemergency medicinetrauma-induced coagulopathytraumamurine polytrauma modelpolytraumacoagulopathycritical careresuscitation

Effect of Irrigation Fluid Composition on Hemostasis in Mouse Bleeding Models. Shock (2022)

Experimental Fibrosis Alters Matrix-Bound Vesicles Cargo That Do Not Revert After Histologic Recovery. Journal of Hepatology (2022)

Toshifumi SatoBashar MatourJiang LiMichael MerchantDaniel WilkeyKenichi IkejimaStephen BadylakGeorge HusseyMelanie ScottGavin Arteel

dermatologyfibrosishematologyregenerative medicineexperimental medicinematrix biologyhistologic recoveryhepatologyhealth sciencescell biology

Grk2 Regulates Group 2 Innate Lymphoid Cell Mobilization in Sepsis. Molecular Medicine (2022)

Dengming LaiWeiwei ChenKai ZhangMelanie J. ScottYuehua LiTimothy R. BilliarMark A. WilsonJie Fan

immunologymedicineemergency medicineinnate immune systemsepsiscell regulationmolecular medicine

1
2
3
4
5
15
10 / page

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