Faculty

Institution

Unit

Venue

Mark Chance

Professor

Case Western Reserve University

Affiliations

School of Medicine

Nutrition

Mark Chance is currently serving as a Nutrition Professor at Case Western Reserve University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Mark Chance

Case Western Reserve University

Professor

You can click a keyword to filter the displayed items

structural biology molecular biology biophysics protein science biochemistry proteomics protein structure genetics membrane biology enzymes structural molecular biology mass spectrometry cancer biology medicinal research gene expression genomics biomolecular structure synchrotron radiation protein chemistry biological chemistry synchrotron radiation research transition metal chemistry mammalian biology structural genomics rna biology genome biology clinical proteomics redox biology infrared spectroscopy bone research coordination chemistry enzyme inhibition biological inorganic chemistry adaptive immune system cancer genomics molecular physiology biochemical sciences colorectal cancer structure elucidation transcription regulation protein bioinformatics cellular immune responses pathway analysis synchrotron radiation source clinical immunology protein footprinting structural mass spectrometry viral pathogenesis receptor (biochemistry) enzyme catalysis diabetes mellitus synchrotron footprinting hydroxyl radical footprinting human parturition molecular regulation radiation detection radioanalytical chemistry tumor suppressors bacteriology structural composition bone disease bone imaging genome-wide association studies instrument science radiolytic modification structural basis conformational changes synchrotron biosciences protein purification human colorectal cancer monovalent cations lysosomal biogenesis conformational substates x-ray absorption studies structural characterization functional characterization protein crystallography biomolecular structure prediction protein-small molecule interactions proteome research systems biology proteomic technologies

Video Presentations

Notable Scholarly Works

Notable Federal Grants

Collaborators

An Engineered Lactate Oxidase Based Electrochemical Sensor for Continuous Detection of Biomarker Lactic Acid in Human Sweat and Serum. Heliyon (2024)

Qingrong HeCheng WangRohit JainJames ByrnesErik R. FarquharElliot ReedElizabeth BerezovskyMark R. ChanceDavid LodowskiRan An

engineered lactate oxidasehuman sweatelectrochemistrybiomarker lactic acidbiosensorsproteomicsbiochemical engineeringclinical chemistryclinical biochemistryelectrochemical sensorenzymesmolecular diagnosticselectroanalytical chemistryearly detectionbiological engineeringbiomedical engineeringhuman biomonitoringbiomolecular engineeringbiomedical analysiscontinuous detection

A Robust “Bottom Up” Proteomics Pipeline is Integral for Assessing Protein Structure Using Hydroxyl Radical Protein Footprinting Mass Spectrometry.. (2024)

Rohit JainNayeon JeonJanna KiselarMark R. Chance

protein structureproteomics

Evaluating Mass Spectrometry-Based Hydroxyl Radical Protein Footprinting of a Benchtop Flash Oxidation System Against a Synchrotron X-Ray Beamline. Journal of the American Society for Mass Spectrometry (2024)

Rohit JainNanak S. DhillonVijaya Lakshmi KanchustambhamDavid T. LodowskiErik R. FarquharJanna KiselarMark R. Chance

synchrotron x-ray beamlinebiophysicsmass spectrometry

Exploring Temporal and Sex-Linked Dysregulation in Alzheimer Disease Phosphoproteome. iScience (2024)

Serhan YılmazFilipa Blasco Tavares Pereira LopesDaniela SchlatzerRihua WangXin QiMehmet KoyutürkMark R Chance

neurologyproteomicsgeneticsclinical neurosciencealzheimer's diseaseneurosciencesex-linked dysregulation

Human Alveolar Macrophages Display Marked Hypo-Responsiveness to Ifn-γ in Both Proteomic and Gene Expression Analysis. PLoS ONE (2024)

Bonnie A. ThielKathleen C. LundbergDaniela SchlatzerJessica JarvelaQing LiRachel ShawScott M. RebaShane FletcherSara E. BeckloffMark R. ChanceW. Henry BoomRichard F. SilverGurkan Bebek

immunologyproteomicshuman alveolar macrophagesgene expression analysismicrobiologycell biology

Making Proteomics Accessible: Rokaixplorer for Interactive Analysis of Phospho-Proteomic Data. Bioinformatics Advances (2024)

Serhan YılmazFilipa Blasco Tavares Pereira LopesDaniela SchlatzerMarzieh AyatiMark R ChanceMehmet Koyutürk

proteomicsinteractive analysisdata sciencephospho-proteomic databioinformatics

Mass Spectrometry-Based Protein Footprinting Defines the Binding Pocket of Crotonylated H3K14 in the Phd1 Domain of Baf45D Within the Baf Chromatin Remodeling Complex. ACS Bio & Med Chem Au (2024)

Marissa R. MartinezJanna KiselarBenlian WangDipti SadalgeLaura ZawadzkeAsad TaherbhoyDerek MusserYunji DavenportJeremy SetserMark R. ChanceSteve Bellon

biophysicsprotein structuregeneticsmolecular biologychromatin remodelingmass spectrometrystructural biologyprotein science

Methionine Sulfoxide Speciation in Mouse Hippocampus Revealed by Global Proteomics Exhibits Age- and Alzheimer’s Disease-Dependent Changes Targeted to Mitochondrial and Glycolytic Pathways. International Journal of Molecular Sciences (2024)

Filipa Blasco Tavares Pereira LopesDaniela SchlatzerMengzhen LiSerhan YilmazRihua WangXin QiMarzieh AyatiMehmet KoyutürkMark R. Chance

cognitive neurosciencemolecular neurobiologyneuroscience of agingneurologyproteomicsaging-associated diseasesmolecular scienceglobal proteomicsmouse hippocampusprotein sciencemembrane biologydisease-dependent changesmethionine sulfoxide speciationmolecular neurosciencemammalian biologyglycolytic pathwayscellular neurobiologyredox biologymitochondrial functionneurochemistrymolecular biologyalzheimer's diseaseneuroscience

Multiplex Trifluoromethyl and Hydroxyl Radical Chemistry Enables High-Resolution Protein Footprinting. Analytical Chemistry (2024)

Rohit JainErik R. FarquharNanak S. DhillonNayeon JeonMark R. ChanceJanna Kiselar

hydroxyl radical chemistrymultiplex trifluoromethylanalytical chemistryhigh resolutionhigh-resolution protein

Optimized Trifluoromethylation and Oh Radical Labeling With Radiolysis Provide Two Fold Enhancement in the Resolution of Hydroxyl Radical Protein Footprinting. (2024)

Rohit JainErik R. FarquharNanak S. DhillonNayeon JeonMark R. ChanceJanna Kiselar

radical (chemistry)oh radical labelinghydroxyl radical proteinfold enhancementbiochemical sciencesprotein sciencemembrane biologynanotechnologyprotein foldingmolecular evidencenucleic acidsprotein chemistrymolecular substratesfragmentation effectprotein engineeringbiophysicsgene expressionfree radical biologyredox biologygeneticsbiomolecular engineering

1
2
3
4
5
36
10 / page

Mark Chance

Professor

Case Western Reserve University

Affiliations

School of Medicine

Nutrition

Mark Chance is currently serving as a Nutrition Professor at Case Western Reserve University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Mark Chance

Case Western Reserve University

Professor

You can click a keyword to filter the displayed items

Video Presentations

Notable Scholarly Works

Notable Federal Grants

Collaborators

An Engineered Lactate Oxidase Based Electrochemical Sensor for Continuous Detection of Biomarker Lactic Acid in Human Sweat and Serum. Heliyon (2024)

Qingrong HeCheng WangRohit JainJames ByrnesErik R. FarquharElliot ReedElizabeth BerezovskyMark R. ChanceDavid LodowskiRan An

A Robust “Bottom Up” Proteomics Pipeline is Integral for Assessing Protein Structure Using Hydroxyl Radical Protein Footprinting Mass Spectrometry.. (2024)

Rohit JainNayeon JeonJanna KiselarMark R. Chance

protein structureproteomics

Rohit JainNanak S. DhillonVijaya Lakshmi KanchustambhamDavid T. LodowskiErik R. FarquharJanna KiselarMark R. Chance

synchrotron x-ray beamlinebiophysicsmass spectrometry

Exploring Temporal and Sex-Linked Dysregulation in Alzheimer Disease Phosphoproteome. iScience (2024)

Serhan YılmazFilipa Blasco Tavares Pereira LopesDaniela SchlatzerRihua WangXin QiMehmet KoyutürkMark R Chance

neurologyproteomicsgeneticsclinical neurosciencealzheimer's diseaseneurosciencesex-linked dysregulation

Human Alveolar Macrophages Display Marked Hypo-Responsiveness to Ifn-γ in Both Proteomic and Gene Expression Analysis. PLoS ONE (2024)

Bonnie A. ThielKathleen C. LundbergDaniela SchlatzerJessica JarvelaQing LiRachel ShawScott M. RebaShane FletcherSara E. BeckloffMark R. ChanceW. Henry BoomRichard F. SilverGurkan Bebek

immunologyproteomicshuman alveolar macrophagesgene expression analysismicrobiologycell biology

Making Proteomics Accessible: Rokaixplorer for Interactive Analysis of Phospho-Proteomic Data. Bioinformatics Advances (2024)

Serhan YılmazFilipa Blasco Tavares Pereira LopesDaniela SchlatzerMarzieh AyatiMark R ChanceMehmet Koyutürk

proteomicsinteractive analysisdata sciencephospho-proteomic databioinformatics

Mass Spectrometry-Based Protein Footprinting Defines the Binding Pocket of Crotonylated H3K14 in the Phd1 Domain of Baf45D Within the Baf Chromatin Remodeling Complex. ACS Bio & Med Chem Au (2024)

Marissa R. MartinezJanna KiselarBenlian WangDipti SadalgeLaura ZawadzkeAsad TaherbhoyDerek MusserYunji DavenportJeremy SetserMark R. ChanceSteve Bellon

biophysicsprotein structuregeneticsmolecular biologychromatin remodelingmass spectrometrystructural biologyprotein science

Filipa Blasco Tavares Pereira LopesDaniela SchlatzerMengzhen LiSerhan YilmazRihua WangXin QiMarzieh AyatiMehmet KoyutürkMark R. Chance

Multiplex Trifluoromethyl and Hydroxyl Radical Chemistry Enables High-Resolution Protein Footprinting. Analytical Chemistry (2024)

Rohit JainErik R. FarquharNanak S. DhillonNayeon JeonMark R. ChanceJanna Kiselar

hydroxyl radical chemistrymultiplex trifluoromethylanalytical chemistryhigh resolutionhigh-resolution protein

Optimized Trifluoromethylation and Oh Radical Labeling With Radiolysis Provide Two Fold Enhancement in the Resolution of Hydroxyl Radical Protein Footprinting. (2024)

Rohit JainErik R. FarquharNanak S. DhillonNayeon JeonMark R. ChanceJanna Kiselar

1
2
3
4
5
36
10 / page

Similar Faculty Members

Salvatore Vincent Pizzo

Institution

Duke University

pharmacology

biochemistry

Jens Meiler

Institution

Vanderbilt University

molecular informatics

biomolecular engineering

Walter Chazin

Institution

Vanderbilt University

molecular biology

proteomics

Nikolay Dokholyan

Institution

University of North Carolina at Chapel Hill

David Fenyo

Institution

New York University

health informatics

computational biology

Michael B. Yaffe

Institution

Massachusetts Institute of Technology

immunology

dna damage response

Garry Nolan

Institution

Stanford University

immunology

cell biology

Andrew Emili

Institution

Boston University

interactomics

biomedical informatics

Peter Kuhn

Institution

University of Southern California

cancer letter

pathology

Christopher Glass

Institution

University of California, San Diego

metabolic disorder

molecular metabolism

Similar Faculty Members

Salvatore Vincent Pizzo

Institution

Duke University

pharmacology

biochemistry

Jens Meiler

Institution

Vanderbilt University

molecular informatics

biomolecular engineering

Walter Chazin

Institution

Vanderbilt University

molecular biology

proteomics

Nikolay Dokholyan

Institution

University of North Carolina at Chapel Hill

David Fenyo

Institution

New York University

health informatics

computational biology

Michael B. Yaffe

Institution

Massachusetts Institute of Technology

immunology

dna damage response

Garry Nolan

Institution

Stanford University

immunology

cell biology

Andrew Emili

Institution

Boston University

interactomics

biomedical informatics

Peter Kuhn

Institution

University of Southern California

cancer letter

pathology

Christopher Glass

Institution

University of California, San Diego

metabolic disorder

molecular metabolism