Faculty

Institution

Unit

Venue

Louis B. Hersh

Professor

University of Kentucky

Affiliations

College of Medicine

Molecular and Cellular Biochemistry

Louis B. Hersh is currently serving as a College Of Medicine Professor at University of Kentucky.

Honors

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Experiences

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Education

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Louis B. Hersh

University of Kentucky

Professor

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neuroscience biochemistry pharmacology enzymes neurology protein science membrane biology neurochemistry alzheimer's disease gene expression mammalian biology neuroanatomy neuropharmacology molecular neurobiology molecular neuroscience enzyme inhibition biological chemistry neurophysiology molecular physiology redox biology brain science biochemical sciences gene regulation protein expression liver physiology enzyme catalysis medicinal research protein chemistry choline acetyltransferase clinical neuroscience protein transport insulin-degrading enzyme structural molecular biology respiratory medicine molecular regulation transcription regulation cholinergic neurons peptides vascular biology cellular neurobiology neutral endopeptidase animal physiology molecular neurodegeneration biochemical genetics biomolecular interactions membrane transport cholinergic innervation puromycin-sensitive aminopeptidase plo biology gene transfer protein function cell regulation neural science gene function insulin signaling immunochemistry neurotransmission human striatum rat brain mammalian physiology catalyst activation molecular basis integrative biology protein secretion mutagenesis neuroinflammation mitochondrial function molecular evidence basal forebrain subsite specificity transgenic mice vesicular acetylcholine transporter human choline acetyltransferase globus pallidus bovine brain morphologic alterations medicine diabetes therapies amyloid beta peptide translational research diabetes research degenerative pathology degenerative disease

Notable Scholarly Works

Notable Federal Grants

Collaborators

Development and Characterization of Nanobodies That Specifically Target the Oncogenic Phosphatase of Regenerating Liver-3 (Prl-3) and Impact Its Interaction With a Known Binding Partner, Cnnm3. PLoS ONE (2023)

Caroline N. SmithKyle KihnZachary A. WilliamsonK. Martin ChowLouis B. HershKonstantin V. KorotkovDaniel DeredgeJessica S. Blackburn

pharmacologynanomedicinemembrane biologynanobiotechnologytumor targetingprotein engineeringliver cancerliver physiologyenzyme inhibitiondevelopmental biologyoncogenic phosphatasemedicinal researchcell biologybiomolecular interactionsplo biologyenzymesregenerative medicineenzyme specificity

Structure of Puromycin-Sensitive Aminopeptidase and Polyglutamine Binding. PLoS ONE (2023)

Sowmya MadabushiK. Martin ChowEun Suk SongAnwesha GoswamiLouis B. HershDavid W. Rodgers

pharmacologymedicinal chemistrybiomolecular structurepuromycin-sensitive aminopeptidasestructural biologyprotein structurebiochemistrypolyglutamine bindingmolecular biologystructural molecular biologyplo biologyenzymesprotein science

Abstract 672: Development and Validation of Nanobodies Specific to the Oncogenic Phosphatase Protein Tyrosine Phosphatase 4A3 (Ptp4A3 or Prl-3). Cancer Research (2022)

Caroline Noel SmithKyle KihnZachary A. WilliamsonK. Martin ChowLouis B. HershKonstantin KorotkovDaniel DeredgeJessica S. Blackburn

pharmaceutical nanotechnologypharmacologynanomedicinenanotechnologycancer biologyhealth sciencescancer treatmenttumor targetingnanobiotechnologycancer researchoncologytumor biologymedicinal researchbiomedical engineering

Aerosol Capture and Coronavirus Spike Protein Deactivation by Enzyme Functionalized Antiviral Membranes. Communications Materials (2022)

Rollie MillsRonald J. VoglerMatthew BernardJacob ConcolinoLouis B. HershYinan WeiJeffrey Todd HastingsThomas DziublaKevin C. BaldridgeDibakar Bhattacharyya

virologyaerosol scienceimmunologyenzymesaerosol capture

Toxoplasma Gondii Toxolysin 4 Contributes to Efficient Parasite Egress From Host Cells. mSphere (2021)

My-Hang HuynhMarijo S. RoikoAngelica O. GomesEllyn N. SchinkeAric J. SchultzSwati AgrawalChristine A. OelligTravis R. SextonJessica M. BeauchampJulie LalibertéKomagal Kannan SivaramanLouis B. HershSheena McGowanVern B. Carruthers

microbiologyparasitologyhost cellsimmunologyparasite egresshost-parasite relationships

Abstract 3752: Identification of Nanobodies Specific for the Oncogenic Protein Tyrosine Phosphatase 4A3 (Ptp4A3/Prl-3) That Modulate Its Binding, Stability, and Phosphatase Activity. Cancer Research (2020)

Caroline N. SmithK. Martin ChowLouis B. HershJessica S. Blackburn

pharmacologynanomedicinecancer biologycancer treatmenttumor targetingcancer researchenzyme catalysisoncologyenzyme inhibitionradiation oncologymolecular biologytumor biologymedicinal researchenzymesprotein sciencephosphatase activityenzyme specificity

Development and Characterization of Nanobodies Specifically Targeting the Oncogenic Phosphatase of Regenerating Liver-3 (Prl-3). bioRxiv (Cold Spring Harbor Laboratory) (2020)

Caroline N. SmithKyle KihnZachary A. WilliamsonK. Martin ChowLouis B. HershKonstantin V. KorotkovDaniel DeredgeJessica S. Blackburn

pharmacologynanomedicinemembrane biologytumor targetingliver physiologyenzyme inhibitiondevelopmental biologyoncogenic phosphataseimmunologybiotechnologymedicinal researchtissue engineeringbiomarker targetnanobiotechnologyregenerative medicineenzyme specificity

Exploring Mechanisms of Insulin-Degrading Enzyme Activation and Localization in the Degradation of Amyloid Beta and Insulin. Acta Crystallographica Section A Foundations and Advances (2020)

David RodgersLouis HershEmilia GalperinEun Suk Song

amyloid betaalzheimer's diseasestructural biologyendocrinologyneurosciencestructural chemistrybiochemistrymolecular biologystructural molecular biologyinsulin-degrading enzyme activationcrystallographyprotein transportx-ray crystallographyenzymesprotein scienceprotein chemistry

Immunization of Alpacas ( Em Lama Pacos /Em ) With Protein Antigens and Production of Antigen-Specific Single Domain Antibodies. Journal of Visualized Experiments (2019)

K. Martin ChowSidney W. WhiteheartJeffrey R. SmileySavita SharmaKathy BoazMeggie J. ColemanAlvina MaynardLouis B. HershCraig W. Vander Kooi

protein antigensexperiment designimmunologyvisualizationscientific visualizationantibody engineering

Insulin-Degrading Enzyme is Not Secreted From Cultured Cells. Scientific Reports (2018)

Eun Suk SongDavid W. RodgersLouis B. Hersh

cultured cellsinsulin-degrading enzymecell culturebiochemistrymolecular biologycell biologyenzymes

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Louis B. Hersh

Professor

University of Kentucky

Affiliations

College of Medicine

Molecular and Cellular Biochemistry

Louis B. Hersh is currently serving as a College Of Medicine Professor at University of Kentucky.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Louis B. Hersh

University of Kentucky

Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Caroline N. SmithKyle KihnZachary A. WilliamsonK. Martin ChowLouis B. HershKonstantin V. KorotkovDaniel DeredgeJessica S. Blackburn

Structure of Puromycin-Sensitive Aminopeptidase and Polyglutamine Binding. PLoS ONE (2023)

Sowmya MadabushiK. Martin ChowEun Suk SongAnwesha GoswamiLouis B. HershDavid W. Rodgers

Abstract 672: Development and Validation of Nanobodies Specific to the Oncogenic Phosphatase Protein Tyrosine Phosphatase 4A3 (Ptp4A3 or Prl-3). Cancer Research (2022)

Caroline Noel SmithKyle KihnZachary A. WilliamsonK. Martin ChowLouis B. HershKonstantin KorotkovDaniel DeredgeJessica S. Blackburn

Aerosol Capture and Coronavirus Spike Protein Deactivation by Enzyme Functionalized Antiviral Membranes. Communications Materials (2022)

Rollie MillsRonald J. VoglerMatthew BernardJacob ConcolinoLouis B. HershYinan WeiJeffrey Todd HastingsThomas DziublaKevin C. BaldridgeDibakar Bhattacharyya

virologyaerosol scienceimmunologyenzymesaerosol capture

Toxoplasma Gondii Toxolysin 4 Contributes to Efficient Parasite Egress From Host Cells. mSphere (2021)

microbiologyparasitologyhost cellsimmunologyparasite egresshost-parasite relationships

Caroline N. SmithK. Martin ChowLouis B. HershJessica S. Blackburn

Development and Characterization of Nanobodies Specifically Targeting the Oncogenic Phosphatase of Regenerating Liver-3 (Prl-3). bioRxiv (Cold Spring Harbor Laboratory) (2020)

Caroline N. SmithKyle KihnZachary A. WilliamsonK. Martin ChowLouis B. HershKonstantin V. KorotkovDaniel DeredgeJessica S. Blackburn

Exploring Mechanisms of Insulin-Degrading Enzyme Activation and Localization in the Degradation of Amyloid Beta and Insulin. Acta Crystallographica Section A Foundations and Advances (2020)

David RodgersLouis HershEmilia GalperinEun Suk Song

Immunization of Alpacas ( Em Lama Pacos /Em ) With Protein Antigens and Production of Antigen-Specific Single Domain Antibodies. Journal of Visualized Experiments (2019)

K. Martin ChowSidney W. WhiteheartJeffrey R. SmileySavita SharmaKathy BoazMeggie J. ColemanAlvina MaynardLouis B. HershCraig W. Vander Kooi

protein antigensexperiment designimmunologyvisualizationscientific visualizationantibody engineering

Insulin-Degrading Enzyme is Not Secreted From Cultured Cells. Scientific Reports (2018)

Eun Suk SongDavid W. RodgersLouis B. Hersh

cultured cellsinsulin-degrading enzymecell culturebiochemistrymolecular biologycell biologyenzymes

1
2
3
4
5
23
10 / page

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University of California, Los Angeles

molecular informatics

proteomic technologies

Heidi E. Hamm, Ph.D.

Institution

Vanderbilt University

neuroscience

photoreceptor cell

Francis Castellino

Institution

University of Notre Dame

pharmacology

biochemistry

Sushil Mahata

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metabolic disorder

hormone secretion

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imaging genomics

cell biology

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membrane transport

electrophysiology

Tadashi Inagami

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cardiovascular disease

hypertension

Kevin Campbell

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neuroscience

membrane biology

Richard Mains

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endocrine mechanism

psychoneuroendocrinology

Krzysztof Palczewski

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biomedical informatics

retinal diseases