Faculty

Institution

Unit

Venue

Richard Mains

Professor of Neuroscience

University of Connecticut

Richard Mains is currently serving as a Professor of Neuroscience at University of Connecticut.

Honors

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Experiences

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Education

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Richard Mains

University of Connecticut

Professor of Neuroscience

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biochemistry neuroscience pharmacology molecular biology endocrinology enzymes protein science membrane biology biological chemistry peptides mammalian biology gene expression pituitary gland structural biology molecular neuroscience neurochemistry protein structure redox biology protein chemistry molecular physiology peptide science molecular neurobiology cell signaling endocrine research protein secretion cellular neurobiology enzyme catalysis peptidylglycine a-amidating monooxygenase cellular physiology structural molecular biology protein function enzyme inhibition molecular cell biology brain science biochemical sciences animal physiology neural science biocatalysis clinical neuroscience biological inorganic chemistry medicinal research protein expression protein transport liver physiology protein biosynthesis cellular biochemistry neurotransmission cellular biology neuropeptides cell physiology molecular regulation intracellular trafficking pharmacokinetics peptide amidation rna biology brain function peptide synthesis peptidylglycine a-hydroxylating monooxygenase endocrine oncology comparative endocrinology cell regulation protein synthesis in vivo systems adrenocorticotropic hormone peptide alpha-amidation activity neuroendocrine cells secretory granules bioactive peptides catalytic core peptide processing enzyme primary cultures posttranslational processing secretory granule endocytic trafficking common precursor molecular oxygen physiology regulated secretion addiction biology human biology psychoneuroendocrinology drug abuse

Notable Scholarly Works

Notable Federal Grants

Collaborators

Peptidylglycine Alpha-Amidating Monooxygenase as a Therapeutic Target or Biomarker. Authorea (Authorea) (2024)

David MerklerAidan HawleyBetty EipperRichard Mains

peptidylglycine alpha-amidating monooxygenasebiomarker targetpharmacologybiomarkerspeptidespharmacokineticspeptide scienceredox biologytherapeutic targetsenzymesdrug discoverymolecular biologymedicinal researchprotein sciencemembrane biologybiochemistry

Dataset Related to Article"Germline Loss-Of-Function Pam Variants Are Enriched in Subjects With Pituitary Hypersecretion". Zenodo (CERN European Organization for Nuclear Research) (2023)

Giampaolo TrivellinAdrian F. DalyLaura C. Hernández-RamírezElisa AraldiChristina TatsiRyan K. DaleGus FridellArjun MittalFabio R. FauczJames R. IbenTianwei LiEleonora VitaliStanko S. StojilkovicPeter KamenickyChiara VillaBertrand BaussartPrashant ChittiboinaCamilo ToroWilliam A. GahlErica A. EugsterLuciana A. NavesMarie-Lise Jaffrain-ReaWouter W. De HerderSebastian JCMM NeggersPatrick PetrossiansAlbert BeckersAndrea G. LaniaRichard E. MainsBetty A. EipperConstantine A. Stratakis

nuclear physicsbiostatisticsnuclear sciencepituitary hypersecretion

Germline Loss-Of-Function Pam Variants Are Enriched in Subjects With Pituitary Hypersecretion. Frontiers in Endocrinology (2023)

Giampaolo TrivellinAdrian F. DalyLaura C. Hernández-RamírezElisa AraldiChristina TatsiRyan K. DaleGus FridellArjun MittalFabio R. FauczJames R. IbenTianwei LiEleonora VitaliStanko S. StojilkovicPeter KamenickyChiara VillaBertrand BaussartPrashant ChittiboinaCamilo ToroWilliam A. GahlErica A. EugsterLuciana A. NavesMarie-Lise Jaffrain-ReaWouter W. de HerderSebastian JCMM NeggersPatrick PetrossiansAlbert BeckersAndrea G. LaniaRichard E. MainsBetty A. EipperConstantine A. Stratakis

immunologypharmacologyendocrinologygeneticsgeriatric endocrinologypituitary hypersecretionhuman geneticsendocrine research

Structure of the Sec14 Domain of Kalirin Reveals a Distinct Class of Lipid-Binding Module in Rhogefs. Nature Communications (2023)

Yunfeng LiYulia PustovalovaTzanko I. DoukovJeffrey C. HochRichard E. MainsBetty A. EipperBing Hao

protein structureliver physiologycell biologykey sitedistinct classbiomolecular structurestructural biologyprotein sciencemembrane biologylipid sciencemembrane proteinsmolecular diversitylipid-binding modulebiophysicslipoprotein metabolismmolecular structuremolecular biologystructural molecular biologysecretory pathwaysignal transduction

Peptidylglycine α‐Amidating Monooxygenase as a Therapeutic Target or Biomarker for Human Diseases. British Journal of Pharmacology (2022)

David J. MerklerAidan J. HawleyBetty A. EipperRichard E. Mains

medicinal chemistrymedicinereceptorsbiomarkerspharmacologypeptidesenzyme inhibitionbiomarker targetpeptide sciencepharmacokineticshuman diseasespharmacotherapytherapeutic targetsenzymesmedicinal researchbiomarker (medicine)clinical pharmacologybiochemistry

Regulated Processing and Secretion of a Peptide Precursor in Cilia. Proceedings of the National Academy of Sciences (2022)

Raj LuxmiRichard E. MainsBetty A. EipperStephen M. King

physiologypeptide precursorprotein secretionmolecular biologysignal transductionmembrane biologycell biology

Ciliary Generation of a Peptidergic Sexual Signal. bioRxiv (Cold Spring Harbor Laboratory) (2021)

Raj LuxmiRichard E. MainsBetty A. EipperStephen M. King

physiologymolecular biologypeptidergic sexual signaldevelopmental biologyciliary generationmembrane biology

Commentary on: Peptidylglycine ?-Amidating Monooxygenase is Required for Atrial Secretory Granule Formation. Journal of Clinical Cardiology (2021)

Emil Daniel BartelsJens Peter GøtzeRichard E MainsBetty A Eipper

physiologycardiologypharmacologypharmacokineticscardiovascular researchenzymesbiochemistrycardiovascular pharmacology

Multiple Roles for Peptidylglycine α‐Amidating Monooxygenase in the Response to Hypoxia. Journal of Cellular Physiology (2021)

Vishwanatha K. S. RaoBetty A. EipperRichard E. Mains

physiologypharmacologycellular physiologypharmacokineticsredox biologycell physiologyenzymeshypoxia (medicine)peptidylglycine a-amidating monooxygenasemultiple rolesmembrane biologybiochemistry

PAM: Diverse Roles in Neuroendocrine Cells, Cardiomyocytes, and Green Algae. FEBS Journal (2021)

Nils BäckRichard E. MainsBetty A. Eipper

neurologyendocrinologybiologyneuroendocrine cellsalgal biologygreen algaeneuroscience

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Richard Mains

Professor of Neuroscience

University of Connecticut

Richard Mains is currently serving as a Professor of Neuroscience at University of Connecticut.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Richard Mains

University of Connecticut

Professor of Neuroscience

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Peptidylglycine Alpha-Amidating Monooxygenase as a Therapeutic Target or Biomarker. Authorea (Authorea) (2024)

David MerklerAidan HawleyBetty EipperRichard Mains

Dataset Related to Article"Germline Loss-Of-Function Pam Variants Are Enriched in Subjects With Pituitary Hypersecretion". Zenodo (CERN European Organization for Nuclear Research) (2023)

nuclear physicsbiostatisticsnuclear sciencepituitary hypersecretion

Germline Loss-Of-Function Pam Variants Are Enriched in Subjects With Pituitary Hypersecretion. Frontiers in Endocrinology (2023)

Giampaolo TrivellinAdrian F. DalyLaura C. Hernández-RamírezElisa AraldiChristina TatsiRyan K. DaleGus FridellArjun MittalFabio R. FauczJames R. IbenTianwei LiEleonora VitaliStanko S. StojilkovicPeter KamenickyChiara VillaBertrand BaussartPrashant ChittiboinaCamilo ToroWilliam A. GahlErica A. EugsterLuciana A. NavesMarie-Lise Jaffrain-ReaWouter W. de HerderSebastian JCMM NeggersPatrick PetrossiansAlbert BeckersAndrea G. LaniaRichard E. MainsBetty A. EipperConstantine A. Stratakis

immunologypharmacologyendocrinologygeneticsgeriatric endocrinologypituitary hypersecretionhuman geneticsendocrine research

Structure of the Sec14 Domain of Kalirin Reveals a Distinct Class of Lipid-Binding Module in Rhogefs. Nature Communications (2023)

Yunfeng LiYulia PustovalovaTzanko I. DoukovJeffrey C. HochRichard E. MainsBetty A. EipperBing Hao

Peptidylglycine α‐Amidating Monooxygenase as a Therapeutic Target or Biomarker for Human Diseases. British Journal of Pharmacology (2022)

David J. MerklerAidan J. HawleyBetty A. EipperRichard E. Mains

Regulated Processing and Secretion of a Peptide Precursor in Cilia. Proceedings of the National Academy of Sciences (2022)

Raj LuxmiRichard E. MainsBetty A. EipperStephen M. King

physiologypeptide precursorprotein secretionmolecular biologysignal transductionmembrane biologycell biology

Ciliary Generation of a Peptidergic Sexual Signal. bioRxiv (Cold Spring Harbor Laboratory) (2021)

Raj LuxmiRichard E. MainsBetty A. EipperStephen M. King

physiologymolecular biologypeptidergic sexual signaldevelopmental biologyciliary generationmembrane biology

Commentary on: Peptidylglycine ?-Amidating Monooxygenase is Required for Atrial Secretory Granule Formation. Journal of Clinical Cardiology (2021)

Emil Daniel BartelsJens Peter GøtzeRichard E MainsBetty A Eipper

physiologycardiologypharmacologypharmacokineticscardiovascular researchenzymesbiochemistrycardiovascular pharmacology

Multiple Roles for Peptidylglycine α‐Amidating Monooxygenase in the Response to Hypoxia. Journal of Cellular Physiology (2021)

Vishwanatha K. S. RaoBetty A. EipperRichard E. Mains

physiologypharmacologycellular physiologypharmacokineticsredox biologycell physiologyenzymeshypoxia (medicine)peptidylglycine a-amidating monooxygenasemultiple rolesmembrane biologybiochemistry

PAM: Diverse Roles in Neuroendocrine Cells, Cardiomyocytes, and Green Algae. FEBS Journal (2021)

Nils BäckRichard E. MainsBetty A. Eipper

neurologyendocrinologybiologyneuroendocrine cellsalgal biologygreen algaeneuroscience

1
2
3
4
5
30
10 / page

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neuroscience

nervous system

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molecular metabolism

neuron

Ralph Bradshaw

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University of California, Irvine

theoretical biology

molecular and cellular biology

Heidi E. Hamm, Ph.D.

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Palmer Taylor

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University of California, San Diego

medicinal chemistry

chemistry

Vsevolod Gurevich

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molecular biology

arrestin proteins

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steroid metabolism

endocrine mechanism

Harvey R. Herschman

Institution

University of California, Los Angeles

imaging genomics

cell biology

Francis Castellino

Institution

University of Notre Dame

pharmacology

biochemistry

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Vanderbilt University

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