Faculty

Institution

Unit

Venue

In-Kwon Kim

Associate Professor

University of Cincinnati

Affiliations

College of Arts and Sciences

Chemistry

In-kwon Kim is currently serving as a Chemistry Associate Professor at University of Cincinnati.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

In-Kwon Kim

University of Cincinnati

Associate Professor

You can click a keyword to filter the displayed items

molecular biology biochemistry structural biology protein science protein structure enzymes structural molecular biology genetics dna repair biomolecular structure gene expression biological chemistry enzyme inhibition pharmacology membrane biology nucleic acids protein x-ray crystallography biophysical chemistry redox biology molecular cell biology biological inorganic chemistry sars-cov-2 virus research cancer cells biochemical sciences protein genetics protein function multi-protein assembly protein chemistry enzyme catalysis genome biology in vivo systems treatment and prevention functional modification cancer biology structural bioinformatics structure-function enzyme kinetics enzyme specificity molecular substrates dna ends cancer cell death replication fork stalling atypical brct-brct interaction cell death molecular cancer leukemia mammalian biology apoptosis tumor suppressors cancer growth selective separation localized excited state protein assembly signaling pathways endocrine-related cancers hormonal receptor protein purification protein expression viral structural protein integrative biology polymer engineering biopolymer gel biocatalysis conjugated polymers dna-bound states flexible tyrosine clasp substrate-binding element nick recognition modules efficient disassembly androgen receptor ar life cycle flexible dna repair specific substrate recognition conformational switch nuclease activities nadph-dependent quinone oxidoreductase rational drug design future medicinal chemistry biomolecular engineering drug discovery

Notable Scholarly Works

Notable Federal Grants

Collaborators

Deltex Family E3 Ligases Specifically Ubiquitinate the Terminal Adp-Ribose of Poly(Adp-Ribosyl)Ation. Biochemical and Biophysical Research Communications (2024)

Matthew KellyChase DietzSamuel KassonYong ZhangMichael J HoltzmanIn-Kwon Kim

dermal structurebiological chemistryspecific resistancebiochemistrycell biologybiosensorsbiophysical chemistrybiochemical sciencesprotein sciencemembrane biologymolecular evidencepeptide sciencetumor biologygene expressionpharmacologyenzyme inhibitiondeltex familyhost specificityterminal adp-ribosemolecular basis

Adp-Ribose-Acceptor Hydrolase 2 ( Arh2 ) Deficiency Results in Cardiac Dysfunction, Tumorigenesis, Inflammation, and Decreased Survival. bioRxiv (Cold Spring Harbor Laboratory) (2023)

Jiro KatoSachiko YamashitaHiroko Ishiwata-EndoShunya OkaZu-Xi YuChengyu LiuDanielle A. SpringerAudrey NoguchiMorteza PeiraviVictoria HoffmannMartin J. LizakMatthew MedearisIn-Kwon KimJoel Moss

enzyme catalysisbiochemistrycell biologycardiac dysfunctionlipidsclinical biochemistryenzymescellular enzymologymembrane biologyinflammationcardiologycardiovascular functionreactive oxygen speciesmolecular physiologyenzyme inhibitioncardiovascular physiologyfree radical biologyredox biologygenetics

Atp Enhances the Error-Prone Ribonucleotide Incorporation by the Sars-Cov-2 Rna Polymerase. Biochemical and Biophysical Research Communications (2022)

Yasin PourfarjamZhijun MaIn-Kwon Kim

error-prone ribonucleotide incorporationgeneral virologygene vectorbiological chemistrybiochemistrybiophysical chemistrysars-cov-2biochemical engineeringmolecular virologyviral geneticsenzymesprotein sciencebiochemical sciencesbiological engineeringvirus researchbiochemical interactiongene expressionmolecular biologyrna biology

Enzymatic Coupling of a Classical Luciferase Assay for the Quantitative Monitoring of the Protein‐Free Adp‐Ribose. The FASEB Journal (2022)

Samuel P. KassonIn‐Kwon Kim

immunologyenzyme inhibitionproteomicsquantitative monitoringenzymesenzymatic couplingprotein sciencetumor biologyclassical luciferase assaybiochemistrycell biology

An Atypical Brct-Brct Interaction With Human Dna Ligase Iiiα Compacts the Xrcc1 Scaffold Protein Within a Flexible Dna Repair Complex. Nucleic Acids Research (2021)

atypical brct-brct interactionbiomolecular structuremolecular cell biologygenome surgerynucleic acidsstructural molecular biologymolecular biologydna repairdna replicationgenome instabilitycell biology

Androgen Signaling Uses a Writer and a Reader of Adp-Ribosylation to Regulate Protein Complex Assembly. Nature Communications (2021)

Chun-Song YangKasey JividenTeddy KamataNatalia DworakLuke OostdykBartlomiej RemleinYasin PourfarjamIn-Kwon KimKang-Ping DuTarek AbbasNicholas E. ShermanDavid WottonBryce M. Paschal

signaling pathwaysendocrine-related cancersgene expressioncell signalingtherapeutic targetsmolecular cell biologyandrogen receptormolecular biologyhormonal receptorar life cyclecancer cellssignal transductionprostate cancercell biology

An Efficient Chemical Screening Method for Structure-Based Inhibitors to Nucleic Acid Enzymes Targeting the Dna Repair-Replication Interface and Sars Cov-2. Methods in enzymology on CD-ROM/Methods in enzymology (2021)

Davide MoianiTodd M. LinkChris A. BroseyPanagiotis KatsonisOlivier LichtargeYoungchang KimAndrzej JoachimiakZhijun MaIn-Kwon KimZamal AhmedDarin E. JonesSusan E. TsutakawaJohn A. Tainer

medicinal chemistryvirus researchstructure-based inhibitorsantiviral researchpharmacologysars-cov-2enzyme inhibitiondna repair-replication interfacebiomolecular engineeringenzymesdrug discoverymolecular biologymolecular diagnosticsdrug targetingenzymatic modificationdna repairprotein scienceantiviral drug development

Reconstitution and Functional Characterization of Sars-Cov-2 Proofreading Complex. Protein Expression and Purification (2021)

Zhijun MaYasin PourfarjamIn-Kwon Kim

virus researchfunctional modificationfunctional characterizationgene expressionsars-cov-2proteomicsprotein functionprotein purificationgeneticsmolecular biologymembrane biologyprotein expressionviral structural proteinprotein scienceprotein engineeringbiological engineering

Selective Monitoring of the Protein-Free Adp-Ribose Released by Adp-Ribosylation Reversal Enzymes. PLoS ONE (2021)

Samuel KassonNuwani DharmapriyaIn-Kwon Kim

immunologymaterials sciencein vitro toxicologygene expressionpharmacologyenzyme inhibitiontreatment and preventionadp-ribosylation reversal enzymesplo biologymolecular and cellular biologyenzymesin vivo systemsprotein scienceselective monitoringmembrane biology

Structural and Biochemical Analysis of Human Adp-Ribosyl-Acceptor Hydrolase 3 (Arh3) Reveals the Basis of Metal Selectivity and Different Roles for the Two Mg Ions. Journal of Biological Chemistry (2021)

metalloproteinsmetal selectivitybiophysical chemistryenzyme inhibitionprotein structureenzymesbiological inorganic chemistrymolecular biologystructural molecular biologybiological chemistryenzyme catalysisstructural biologybiochemical sciencesmg ionsdifferent rolesbiochemistry

1
2
3
4
5
10 / page

In-Kwon Kim

Associate Professor

University of Cincinnati

Affiliations

College of Arts and Sciences

Chemistry

In-kwon Kim is currently serving as a Chemistry Associate Professor at University of Cincinnati.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

In-Kwon Kim

University of Cincinnati

Associate Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Deltex Family E3 Ligases Specifically Ubiquitinate the Terminal Adp-Ribose of Poly(Adp-Ribosyl)Ation. Biochemical and Biophysical Research Communications (2024)

Matthew KellyChase DietzSamuel KassonYong ZhangMichael J HoltzmanIn-Kwon Kim

Adp-Ribose-Acceptor Hydrolase 2 ( Arh2 ) Deficiency Results in Cardiac Dysfunction, Tumorigenesis, Inflammation, and Decreased Survival. bioRxiv (Cold Spring Harbor Laboratory) (2023)

Jiro KatoSachiko YamashitaHiroko Ishiwata-EndoShunya OkaZu-Xi YuChengyu LiuDanielle A. SpringerAudrey NoguchiMorteza PeiraviVictoria HoffmannMartin J. LizakMatthew MedearisIn-Kwon KimJoel Moss

Atp Enhances the Error-Prone Ribonucleotide Incorporation by the Sars-Cov-2 Rna Polymerase. Biochemical and Biophysical Research Communications (2022)

Yasin PourfarjamZhijun MaIn-Kwon Kim

Enzymatic Coupling of a Classical Luciferase Assay for the Quantitative Monitoring of the Protein‐Free Adp‐Ribose. The FASEB Journal (2022)

Samuel P. KassonIn‐Kwon Kim

immunologyenzyme inhibitionproteomicsquantitative monitoringenzymesenzymatic couplingprotein sciencetumor biologyclassical luciferase assaybiochemistrycell biology

An Atypical Brct-Brct Interaction With Human Dna Ligase Iiiα Compacts the Xrcc1 Scaffold Protein Within a Flexible Dna Repair Complex. Nucleic Acids Research (2021)

Androgen Signaling Uses a Writer and a Reader of Adp-Ribosylation to Regulate Protein Complex Assembly. Nature Communications (2021)

Chun-Song YangKasey JividenTeddy KamataNatalia DworakLuke OostdykBartlomiej RemleinYasin PourfarjamIn-Kwon KimKang-Ping DuTarek AbbasNicholas E. ShermanDavid WottonBryce M. Paschal

Davide MoianiTodd M. LinkChris A. BroseyPanagiotis KatsonisOlivier LichtargeYoungchang KimAndrzej JoachimiakZhijun MaIn-Kwon KimZamal AhmedDarin E. JonesSusan E. TsutakawaJohn A. Tainer

Reconstitution and Functional Characterization of Sars-Cov-2 Proofreading Complex. Protein Expression and Purification (2021)

Zhijun MaYasin PourfarjamIn-Kwon Kim

Selective Monitoring of the Protein-Free Adp-Ribose Released by Adp-Ribosylation Reversal Enzymes. PLoS ONE (2021)

Samuel KassonNuwani DharmapriyaIn-Kwon Kim

1
2
3
4
5
10 / page

Similar Faculty Members

Michael A. Kennedy

Institution

Miami University

molecular biology

nmr spectroscopy

Evan R. Kantrowitz

Institution

Boston College

enzymes

biochemistry

Robert Powers

Institution

University of Nebraska–Lincoln

nuclear magnetic resonance spectroscopy

biomolecular structure

Mary F. Roberts

Institution

Boston College

biochemistry

enzymes

Brian F. Volkman, PhD

Institution

Medical College of Wisconsin

molecular biology

nmr spectroscopy

Carol Fierke

Institution

University of Michigan

biochemistry

molecular biology

Timothy Gerald Palzkill

Institution

Baylor College of Medicine

molecular biology

drug resistance mechanisms

Liz Hedstrom

Institution

Brandeis University

mtor inhibitors

protein structure

Peter G.W. Gettins

Institution

University of Illinois Chicago

biochemistry

molecular biology

Stephen K. Burley

Institution

Rutgers University–Newark

protein structure

clinical proteomics

Similar Faculty Members

Michael A. Kennedy

Institution

Miami University

molecular biology

nmr spectroscopy

Evan R. Kantrowitz

Institution

Boston College

enzymes

biochemistry

Robert Powers

Institution

University of Nebraska–Lincoln

nuclear magnetic resonance spectroscopy

biomolecular structure

Mary F. Roberts

Institution

Boston College

biochemistry

enzymes

Brian F. Volkman, PhD

Institution

Medical College of Wisconsin

molecular biology

nmr spectroscopy

Carol Fierke

Institution

University of Michigan

biochemistry

molecular biology

Timothy Gerald Palzkill

Institution

Baylor College of Medicine

molecular biology

drug resistance mechanisms

Liz Hedstrom

Institution

Brandeis University

mtor inhibitors

protein structure

Peter G.W. Gettins

Institution

University of Illinois Chicago

biochemistry

molecular biology

Stephen K. Burley

Institution

Rutgers University–Newark

protein structure

clinical proteomics