Faculty

Institution

Unit

Venue

Kevin Pinney

Professor of Chemistry

Baylor University

Affiliations

College of Arts & Sciences

Chemistry and Biochemistry

Kevin Pinney is currently serving as a Chemistry And Biochemistry Professor of Chemistry at Baylor University.

Honors

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Experiences

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Education

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Kevin Pinney

Baylor University

Professor of Chemistry

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pharmacology medicinal chemistry drug discovery oncology medicine pharmaceutical chemistry enzyme inhibition medicinal research biomolecular engineering cancer research cancer biology tumor biology vascular biology chemical synthesis organic synthesis cancer treatment tumor targeting biological evaluation clinical chemistry cancer care bioorganic chemistry anti-cancer agents drug targeting drug development dermatology pharmacotherapy cancer imaging natural product research molecular cancer pharmaceutical sciences synthetic chemistry tubulin polymerization photomedicine biomedical imaging structural chemistry vascular pharmacology natural product synthesis cancer management anticancer agents protein science biological chemistry functional modification therapeutic imaging angiogenesis rational drug design vascular disease vascular disrupting agents vascular disrupting agent estrogen receptor biochemical evaluation nuclear medicine medical mycology pharmaceutical biotechnology therapeutic efficacy tubulin assembly activatable prodrug conjugates biomolecular interactions integrative biology vascular malformations apoptosis catalytic synthesis experimental synthesis blood flow active ingredient pharmaceutical research selective toxicity remedial action molecular design magnetic resonance imaging biological assessment preclinical tumor imaging endothelial apoptosis benzosuberene analogs cancer chemotherapy combretastatin nitrogen-containing derivatives aryl azide derivatives synthetic organic chemistry

Notable Scholarly Works

Notable Federal Grants

Collaborators

Evaluating Therapeutic Efficacy of the Vascular Disrupting Agent Oxi8007 Against Kidney Cancer in Mice. Cancers (2025)

Hashini I. WanniarachchiRegan SchuetzeYuling DengKhagendra B. HamalCyprian I. PavlichPouguiniseli E. O. TankoanoCaleb TammingaHans HammersPayal KapurLorena M. A. BuenoRicardo RayasTianyuan WangLi LiuMary Lynn TrawickKevin G. PinneyRalph P. Mason

kidney cancercancer treatmentmedicinecancer researchvascular biology

Abstract 2086 Preliminary Pharmacokinetic Study of Oxi8007, an Effective Vascular Disrupting Agent, in an Orthotopic Renca Tumor-Bearing Balb/C Mouse Model. Journal of Biological Chemistry (2024)

Yuling DengCaleb TammingaKhagendra HamalCyprian PavlichRegan SchuetzeHashini WanniarachchiRalph MasonKevin PinneyMary Trawick

vascular biologypharmacologyoncologytumor biology

Acute Vasculature Disruption in Orthotopic Kidney Tumors Based on Vascular Disrupting Agent (Oxi8007) Examined by Multispectral Optoacoustic Tomography (Msot). Photons Plus Ultrasound: Imaging and Sensing 2021 (2024)

Hashini I. WanniarachchiLorena M. A. BuenoRicardo RayasKhagendra HamalCyprian PavlichMary Lynn TrawickKevin G. PinneyLi LiuRalph P. Mason

orthotopic kidney tumorsangiologytissue imagingophthalmologyvascular diseasesurgical oncologymedical imaginghematologyimaging agentvascular biologyneurologykidney canceracute vasculature disruptiononcologybiomedical imagingvascular surgerymultispectral optoacoustic tomographynephrologyurologycancer imagingoncologic imagingvascular disrupting agent

Application of Chlorosulfonyl Isocyanate (Csi) in the Synthesis of Fused Tetracyclic Ketone Ring Systems. The Journal of Organic Chemistry (2024)

Jennifer M. VanNattaHaichan NiuGraham J. CarlsonKevin G. Pinney

fused tetracyclic ketoneorganic chemistrysynthetic chemistryorganic synthesischlorosulfonyl isocyanatechemical synthesischemistry

Design, Synthesis and Biological Evaluation of 2-Phenyl Indole Analogues of Oxi8006 as Colchicine Site Inhibitors of Tubulin Polymerization and Vascular Disrupting Agents. Bioorganic & Medicinal Chemistry (2024)

Rebecca VairinCaleb TammingaZhe ShiChristian BorchardtJayaram JambulapatiRuoli BaiHashini WanniarachchiLorena BuenoErnest HamelRalph P MasonMary Lynn TrawickKevin G Pinney

synthetic biologyvascular disrupting agentsbiochemistrychemical biotechnologybiomolecular engineeringvascular biologybiological engineeringmedicinal chemistrypeptide engineeringtubulin polymerizationbiochemical engineeringnatural product researchbioactive compoundsbiological evaluationpeptide sciencecolchicine site inhibitorsmolecular dockingpharmaceutical chemistryenzyme inhibitionmedicinal researchbioorganic chemistryenzyme specificity

Drug-Linker Constructs Bearing Unique Dual-Mechanism Tubulin Binding Payloads Tethered Through Cleavable and Non-Cleavable Linkers. Tetrahedron (2024)

Jacob W FordJennifer M VanNattaDeboprosad MondalChen-Ming LinYuling DengRuoli BaiErnest HamelMary Lynn TrawickKevin G Pinney

biochemistrydrug deliverybiomolecular engineeringdrug-linker constructsbiomedical engineeringunique dual-mechanism tubulinnon-cleavable linkers

Abstract 1272: Aberrantly Exposed Phosphatidylserine as a Drug Delivery Target in Pancreatic Cancer. Cancer Research (2023)

Natalie Zara PhinneyXianming HuangMary Lynn TrawickKevin PinneyRolf Brekken

pharmacologycancer biologydrug delivery targetcancer researchoncologydrug deliverypancreatic cancer

Abstract 1545: Targeting Anticancer Agents to the Tumor Microenvironment With Cathepsin B Cleavable Drug-Linker Conjugates of Phosphatidylserine-Binding Proteins. Cancer Research (2023)

Yuling DengJacob W. FordJenny M. VanNattaCasey J. MaguireDeboprosad MondalNatalie Z. PhinneyRolf A. BrekkenKevin G. PinneyMary Lynn Trawick

tumor targetingdrug targetinganticancer agentscancer biologynanomedicinemolecular cancercancer researchpharmaceuticstumor biologypharmacologycancer treatmentoncologycancer carecancer managementphosphatidylserine-binding proteinstumor microenvironmentradiation oncologymedicinal researchbiomedical engineering

Ccdc 2157502: Experimental Crystal Structure Determination. The Cambridge Structural Database (2023)

Rao, YuPalumbo, Chad T.Venkatesh, AmritKeener, MeganStevanato, GabrieleChauvin, Anne-SophieMenzildjian, GeorgesKuzin, SergeiYulikov, MaximJeschke, GunnarLesage, AnneMazzanti, MarinellaEmsley, Lyndon

crystal diffraction studycrystal researchchemical structurebiophysicscrystal structuresccdc 2157502structural chemistrystructure determinationcrystal engineeringcrystallographystructure elucidationdeposited datasetchemistry

Structure Guided Design, Synthesis, and Biological Evaluation of Oxetane-Containing Indole Analogues. Bioorganic & Medicinal Chemistry (2023)

Wen RenRebecca VairinJacob D. WardRicardo FrancisJenny VanNattaRuoli BaiPouguiniseli E. TankoanoYuling DengErnest HamelMary Lynn TrawickKevin G. Pinney

medicinal chemistrychemical engineeringdrug discoverybiochemical sciencesbiochemical engineeringbiological chemistrysynthetic chemistrypharmaceutical biotechnologypharmaceutical chemistrypharmaceutical sciencesbiomolecular engineeringbioorganic chemistrybiomedical engineeringchemical biology

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Kevin Pinney

Professor of Chemistry

Baylor University

Affiliations

College of Arts & Sciences

Chemistry and Biochemistry

Kevin Pinney is currently serving as a Chemistry And Biochemistry Professor of Chemistry at Baylor University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Kevin Pinney

Baylor University

Professor of Chemistry

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Evaluating Therapeutic Efficacy of the Vascular Disrupting Agent Oxi8007 Against Kidney Cancer in Mice. Cancers (2025)

kidney cancercancer treatmentmedicinecancer researchvascular biology

Abstract 2086 Preliminary Pharmacokinetic Study of Oxi8007, an Effective Vascular Disrupting Agent, in an Orthotopic Renca Tumor-Bearing Balb/C Mouse Model. Journal of Biological Chemistry (2024)

Yuling DengCaleb TammingaKhagendra HamalCyprian PavlichRegan SchuetzeHashini WanniarachchiRalph MasonKevin PinneyMary Trawick

vascular biologypharmacologyoncologytumor biology

Hashini I. WanniarachchiLorena M. A. BuenoRicardo RayasKhagendra HamalCyprian PavlichMary Lynn TrawickKevin G. PinneyLi LiuRalph P. Mason

Application of Chlorosulfonyl Isocyanate (Csi) in the Synthesis of Fused Tetracyclic Ketone Ring Systems. The Journal of Organic Chemistry (2024)

Jennifer M. VanNattaHaichan NiuGraham J. CarlsonKevin G. Pinney

fused tetracyclic ketoneorganic chemistrysynthetic chemistryorganic synthesischlorosulfonyl isocyanatechemical synthesischemistry

Rebecca VairinCaleb TammingaZhe ShiChristian BorchardtJayaram JambulapatiRuoli BaiHashini WanniarachchiLorena BuenoErnest HamelRalph P MasonMary Lynn TrawickKevin G Pinney

Drug-Linker Constructs Bearing Unique Dual-Mechanism Tubulin Binding Payloads Tethered Through Cleavable and Non-Cleavable Linkers. Tetrahedron (2024)

Jacob W FordJennifer M VanNattaDeboprosad MondalChen-Ming LinYuling DengRuoli BaiErnest HamelMary Lynn TrawickKevin G Pinney

biochemistrydrug deliverybiomolecular engineeringdrug-linker constructsbiomedical engineeringunique dual-mechanism tubulinnon-cleavable linkers

Abstract 1272: Aberrantly Exposed Phosphatidylserine as a Drug Delivery Target in Pancreatic Cancer. Cancer Research (2023)

Natalie Zara PhinneyXianming HuangMary Lynn TrawickKevin PinneyRolf Brekken

pharmacologycancer biologydrug delivery targetcancer researchoncologydrug deliverypancreatic cancer

Abstract 1545: Targeting Anticancer Agents to the Tumor Microenvironment With Cathepsin B Cleavable Drug-Linker Conjugates of Phosphatidylserine-Binding Proteins. Cancer Research (2023)

Yuling DengJacob W. FordJenny M. VanNattaCasey J. MaguireDeboprosad MondalNatalie Z. PhinneyRolf A. BrekkenKevin G. PinneyMary Lynn Trawick

Ccdc 2157502: Experimental Crystal Structure Determination. The Cambridge Structural Database (2023)

Rao, YuPalumbo, Chad T.Venkatesh, AmritKeener, MeganStevanato, GabrieleChauvin, Anne-SophieMenzildjian, GeorgesKuzin, SergeiYulikov, MaximJeschke, GunnarLesage, AnneMazzanti, MarinellaEmsley, Lyndon

Structure Guided Design, Synthesis, and Biological Evaluation of Oxetane-Containing Indole Analogues. Bioorganic & Medicinal Chemistry (2023)

Wen RenRebecca VairinJacob D. WardRicardo FrancisJenny VanNattaRuoli BaiPouguiniseli E. TankoanoYuling DengErnest HamelMary Lynn TrawickKevin G. Pinney

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