Faculty

Institution

Unit

Venue

Kenyon Daniel

Professor of Instruction

University of South Florida

Affiliations

College of Arts and Sciences

School of Natural Sciences and Mathematics

Department of Molecular Biosciences

Kenyon Daniel is currently serving as a College Of Arts And Sciences Professor of Instruction at University of South Florida.

Honors

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Experiences

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Education

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Kenyon Daniel

University of South Florida

Professor of Instruction

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pharmacology medicinal chemistry oncology drug discovery cancer research medicine cancer treatment enzyme inhibition medicinal research cancer biology cell biology tumor biology biochemistry protein science apoptosis proteomics proteasome inhibitors cell death cancer care molecular cancer leukemia apoptosis inducers molecular pharmacology bioorganic chemistry coordination chemistry biological inorganic chemistry polyphenolics anti-cancer agents pharmaceutical research human cancer cells proteasome inhibition transition metal chemistry pharmacological research cancer cells drug development protein chemistry cancer prevention phytochemistry catalyst activation receptor (biochemistry) tumor targeting drug targeting molecular cell biology cellular biochemistry oncogenes photomedicine biological chemistry breast oncology protein function cell regulation rational drug design molecular docking inorganic compounds therapeutic efficacy in vivo systems tumor suppressors functional modification protein bioinformatics pharmaceutical chemistry therapy resistance herb-drug interactions plant biochemistry phytochemicals short-term variability drug design pyrrolidine dithiocarbamate complex human leukemia cells dietary flavonoids organic copper complexes proteasome activity novel mechanism model development apoptosis induction computational studies pyrrolidine dithiocarbamate-copper complex computational validation biomedical informatics

Notable Scholarly Works

Notable Federal Grants

Collaborators

Biophysical Methods for Attomolar Detection of Compounds Acting on Protein Oligomer States. (2024)

William LawlessRobert SparksMark EschenfelderStephanie KrzypkowskiKenyon DanielWayne Guida

biophysicsattomolar detectionmolecular biophysicsbiophysical methods

Biophysical System for the Detection and Quantification of Changes in Oligomeric States of Sting at Attomolar Concentrations of Clonixeril. (2024)

William LawlessMark EschenfelderRobert SparksSarah LawlessStephanie KrzypkowskiKenyon DanielWayne Guida

pharmacologyoligomeric statesenzymescell biologymolecular biologybiophysical systemgene expressioninhibitory activitynucleic acidsintermediate hostfluorescence spectroscopystructural biologyprotein scienceearly detectionpeptide sciencefunctional selectivityattomolar concentrationsmembrane biologycatalyst activationmammalian biologyenzyme inhibition

Discovery of Clonixeril as a Sub-Femtomolar Modulator of the Human Sting Receptor. (2024)

Robert SparksWilliam LawlessAnna KharitonovaRainer MetcalfJamie NunziataGrace BinderSauradip ChaudhuryChristine GambinoMichelle WildeLinette HardingJaret CrewsMansi GopuEmilia DalamangusSarah LawlessMark EschenfelderRobert GreenElizabeth NompleggiTimothy TranKathy YangDonna TraskPaul ThompsonNiketa PatelRekha PatelWesley BrooksGuy BradleyMildred Acevedo-DuncanAlan MullenJames LeahyKenyon DanielWayne Guida

immunologypharmacologytherapeutic targetsvenomicssub-femtomolar modulatorvascular biologypeptidesinsect sting allergydrug discoveryreceptorsmedicinal researchbiochemistryendocrinologypain medicinepheromone biochemistrypeptide sciencehuman sting receptorplatelet antagonistreceptor (biochemistry)signal transduction

Computational Chemistry Tools. Burger's Medicinal Chemistry and Drug Discovery (2021)

Rainer MetcalfKenyon DanielWesley BrooksWayne Guida

biophysicscomputational chemistrycomputational chemistry toolsmedicinal chemistrydrug discovery

Identifying Biomolecular Targets of the Anticancer Vitamin-E-δ-Tocotrienol Using a Computational Approach: Virtual Target Screening. Clinical Oncology and Research (2020)

Wesley H. BrooksYuri PevznerElza PevznerKenyon G. DanielWayne C. GuidaWesley H. BrooksMokenge P. Malafa

virtual target screeningtumor biologycancer biologydrug targetingclinical mycologybiomolecular targetsmedicinal researchcancer researchanticancer vitamin-e-d-tocotrienolpharmacologymolecular biologymedicineclinical researchcancer treatmentcancer careoncologydrug discoverypharmaceutical research

Abstract 6: Computationally Assisted Target Screening of Sting Agonist for Immunologic Therapy. Cancer Research (2019)

Grace A. BinderChristine S. GambinoAnna KharitonovaRainer S. MetcalfKenyon G. DanielWayne C. Guida

high-throughput screeningcancer screeningimmunologycancer researchtarget screeningimmunologic therapypharmacologyhealth sciencesoncology

Ligand-Mediated Protein Degradation Reveals Functional Conservation Among Sequence Variants of the Cul4-Type E3 Ligase Substrate Receptor Cereblon. Journal of Biological Chemistry (2018)

Afua A. AkuffoAileen Y. AlontagaRainer MetcalfMatthew S. BeattyAndreas BeckerJessica M. McDanielRebecca S. HesterbergWilliam E. GoodheartSteven GunawanMuhammad AyazYan YangMd Rezaul KarimMorgan E. OrobelloKenyon DanielWayne GuidaJeffrey A. YoderAnjali M. RajadhyakshaErnst SchönbrunnHarshani R. LawrenceNicholas J. LawrencePearlie K. Epling-Burnette

molecular neurosciencesequence variantsprotein chemistryprotein sciencebiochemistrymedicinal chemistrymolecular physiologyreceptor (biochemistry)pharmacologymolecular biologymolecular pharmacologybiological chemistryprotein bioinformaticsreceptorsstructural biologybiological inorganic chemistry

Evaluation of Digestion Methods for Analysis of Trace Metals in Mammalian Tissues and Nist 1577c. Analytical Biochemistry (2017)

Grace A. BinderRainer MetcalfZachary AtlasKenyon G. Daniel

spectrochemical analysistrace metalsforensic toxicologygastroenterologybioanalysisdigestion methodsinhibitory activitymetalsmicrobiologyapplied microbiologytoxicologydrug analysisanalytical toxicologyanalytical chemistrymammalian tissuesmass spectrometrymetal toxicitybiomolecular engineeringmaterials science

Intracellular Protein Degradation of Brd4 by Dbet1 Reveals Conserved in Vivo Cereblon Function in Human and Mouse T-Cells. The Journal of Immunology (2017)

Afua Adutwumwa AkuffoAileen AlontagaRainer MetclafMatthew S BeattyJessica McDanielSteven GunawanMuhammad AyazAndreas BeckerRebecca S HesterbergWilliam E GoodheartYan YangKenyon G DanielErnst SchonbrunnWayne GuidaHarshani LawrenceNicholas LawrencePearlie Epling-Burnette

intracellular protein degradationimmunologycell biologystructural biology

Cupriphilic Compounds to Aid in Proteasome Inhibition. Bioorganic & Medicinal Chemistry Letters (2016)

Sreya MukherjeeRobert SparksRainer MetcalfWesley BrooksKenyon DanielWayne C. Guida

proteasome inhibitionmedicinal chemistrybioorganic chemistrycupriphilic compoundspharmacology

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Kenyon Daniel

Professor of Instruction

University of South Florida

Affiliations

College of Arts and Sciences

School of Natural Sciences and Mathematics

Department of Molecular Biosciences

Kenyon Daniel is currently serving as a College Of Arts And Sciences Professor of Instruction at University of South Florida.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Kenyon Daniel

University of South Florida

Professor of Instruction

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Biophysical Methods for Attomolar Detection of Compounds Acting on Protein Oligomer States. (2024)

William LawlessRobert SparksMark EschenfelderStephanie KrzypkowskiKenyon DanielWayne Guida

biophysicsattomolar detectionmolecular biophysicsbiophysical methods

Biophysical System for the Detection and Quantification of Changes in Oligomeric States of Sting at Attomolar Concentrations of Clonixeril. (2024)

William LawlessMark EschenfelderRobert SparksSarah LawlessStephanie KrzypkowskiKenyon DanielWayne Guida

Discovery of Clonixeril as a Sub-Femtomolar Modulator of the Human Sting Receptor. (2024)

Computational Chemistry Tools. Burger's Medicinal Chemistry and Drug Discovery (2021)

Rainer MetcalfKenyon DanielWesley BrooksWayne Guida

biophysicscomputational chemistrycomputational chemistry toolsmedicinal chemistrydrug discovery

Identifying Biomolecular Targets of the Anticancer Vitamin-E-δ-Tocotrienol Using a Computational Approach: Virtual Target Screening. Clinical Oncology and Research (2020)

Wesley H. BrooksYuri PevznerElza PevznerKenyon G. DanielWayne C. GuidaWesley H. BrooksMokenge P. Malafa

Abstract 6: Computationally Assisted Target Screening of Sting Agonist for Immunologic Therapy. Cancer Research (2019)

Grace A. BinderChristine S. GambinoAnna KharitonovaRainer S. MetcalfKenyon G. DanielWayne C. Guida

high-throughput screeningcancer screeningimmunologycancer researchtarget screeningimmunologic therapypharmacologyhealth sciencesoncology

Ligand-Mediated Protein Degradation Reveals Functional Conservation Among Sequence Variants of the Cul4-Type E3 Ligase Substrate Receptor Cereblon. Journal of Biological Chemistry (2018)

Evaluation of Digestion Methods for Analysis of Trace Metals in Mammalian Tissues and Nist 1577c. Analytical Biochemistry (2017)

Grace A. BinderRainer MetcalfZachary AtlasKenyon G. Daniel

Intracellular Protein Degradation of Brd4 by Dbet1 Reveals Conserved in Vivo Cereblon Function in Human and Mouse T-Cells. The Journal of Immunology (2017)

intracellular protein degradationimmunologycell biologystructural biology

Cupriphilic Compounds to Aid in Proteasome Inhibition. Bioorganic & Medicinal Chemistry Letters (2016)

Sreya MukherjeeRobert SparksRainer MetcalfWesley BrooksKenyon DanielWayne C. Guida

proteasome inhibitionmedicinal chemistrybioorganic chemistrycupriphilic compoundspharmacology

1
2
3
4
5
10 / page

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Brian Blagg

Institution

University of Notre Dame

biosynthesis

future medicinal chemistry

Nicholas Farrell

Institution

Virginia Commonwealth University

clinical infectious disease

infectious diseases (medical specialty)

Gregory Thatcher

Institution

University of Arizona

biochemistry

drug development

Kevin Dalby

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anti-cancer agent

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Stephen W. Fesik

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drug discovery

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John Koomen

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proteomics

chemical cleavage mechanisms

Ramzi Mohammad

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future medicinal chemistry

medicinal chemistry

Iwao Ojima

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medicinal chemistry

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pharmacology

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