Faculty

Institution

Unit

Venue

Kelly M. Standifer

Professor and Chair

University of Oklahoma

Affiliations

HEALTH SCIENCES CENTER CAMPUS COLLEGES

College of Pharmacy

Health Sciences Center Graduate College

Kelly M. Standifer is currently serving as a College Of Pharmacy Professor and Chair at University of Oklahoma.

Honors

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Experiences

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Education

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Kelly M. Standifer

University of Oklahoma

Professor and Chair

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neuroscience pharmacology neuropharmacology neurology receptors cell signaling signal transduction pharmacotherapy medicine drug discovery pharmacological research pharmacokinetics neurochemistry neurophysiology clinical pharmacology membrane biology molecular pharmacology protein science peptides brain science experimental pharmacology g protein-coupled receptor medicinal research pain research traumatic brain injury experimental medicine molecular neurobiology mammalian biology addiction biology receptor (biochemistry) translational pharmacology orphan drugs neurotransmission cell regulation cellular neurobiology molecular regulation antisense oligodeoxynucleotides peptide science neuropsychopharmacology psychoneuroendocrinology transcription regulation rat model cellular physiology molecular physiology biological psychiatry applied pharmacology signaling pathways pharmaceutical sciences retina cellular pharmacology neurotology neuropathic pain differential blockade anxiety symptoms opioid receptors preclinical model agonist-induced down-regulation functional selectivity host specificity cell trafficking molecular pain pain therapy baseline correction gene regulation neuroregeneration short-term variability neurodynamics neural science pharmacological characterization selective loss gender effects central opioid analgesia opioid receptor-mediated signalling functional characterization antisense mapping opioid analgesia brain injury post-traumatic stress disorder neuropeptides psychiatry trauma pain mechanism

Notable Scholarly Works

Notable Federal Grants

Collaborators

Impact of Gender, Nop Receptor Knockout Genotype, Stress and Trauma on Cerebral Blood Flow Following Mild Traumatic Brain Injury in Rats: Acute Post-Injury Analysis (Abstract Id: 170164). Journal of Pharmacology and Experimental Therapeutics (2025)

Panini PatankarSoumyabrata MunshiOmar Al YacoubYong ZhangKelly Standifer

cerebral blood flowhead trauma rehabilitationpsychoneuroimmunologytraumaacute post-injury analysisnitrosative stressgenetic basisneuroscienceabstract idneurogeneticspharmacologystress biomarkersphysiologybrain injurystress (biology)psychological traumapost-traumatic stress disorder

Testing the Effect of the Non-Selective Opioid Ppl-138 in a Model of Alcohol Relapse in the Context of Ptsd. Neuropharmacology (2025)

psychiatryalcohol (drug)substance use disordersaddiction medicinealcohol relapsepsychopathologyaddiction treatmentaddictionaddictive behaviorspsychologysubstance useopioid use disordernon-selective opioid ppl-138psychological traumapost-traumatic stress disorder

The Opioid Partial Agonist Ppl‐138 Reduces Alcohol Self‐Administration in Rats Susceptible to Post‐Traumatic Stress Disorder. British Journal of Pharmacology (2025)

post‐traumatic stress disorderneuropharmacologyalcohol (drug)substance use disordersalcohol self‐administrationpharmacologyalcohol dependencepsychologyopioid use disorderbehavioural pharmacologystress (biology)neuropsychopharmacologypsychological traumapost-traumatic stress disorder

Traumatic Brain Injury Induces Nociceptin/Orphanin Fq and Nociceptin Opioid Peptide Receptor Expression Within 24 Hours. International Journal of Molecular Sciences (2024)

Omar N. Al YacoubYong ZhangPanini S. PatankarKelly M. Standifer

receptorsneurochemistryneuropharmacologyneuroprotectionneurosciencepharmacologyphysiology

Recovery From Traumatic Brain Injury is Nociceptin/Orphanin Fq Peptide Receptor Genotype-, Sex-, and Injury Severity-Dependent. Journal of Pharmacology and Experimental Therapeutics (2023)

Omar N. Al YacoubHibah O. AwwadKelly M. Standifer

receptorsneuropeptide receptorsconcussionneurosciencefunctional recoveryneuropeptidestherapeutic targetspeptide sciencepain researchneuropsychopharmacologypsychological traumahead trauma rehabilitationadverse eventsinjury severity-dependentrehabilitationpsychiatryinflammationneuropathic painclinical researchtraumatic brain injury

The Nociceptin/Orphanin Fq Peptide Receptor Antagonist, Sb-612111, Improves Cerebral Blood Flow in a Rat Model of Traumatic Brain Injury. Frontiers in Pharmacology (2023)

Omar N. Al YacoubStefano TarantiniYong ZhangAnna CsiszarKelly M. Standifer

cerebral blood flowreceptorsrat modelneuropharmacologyneurosciencepharmacologyneurologydrug discoverypharmacokineticspeptidestraumatic brain injury

Loss of Nociceptin/Orphanin Fq Peptide Receptor Protects Against Traumatic Brain Injury (Tbi)‐Induced Deficits in Male and Female Rats. The FASEB Journal (2021)

Omar Al YacoubMatthew BaierHibah AwwadKelly Standifer

receptorsneurochemistryneuropeptide receptorsneuropharmacologyneuroprotectionneurosciencepharmacologymammalian biologyneurologyfemale ratspeptidestraumatic brain injury

Modeling Traumatic Brain Injury Combined With Hemorrhagic Shock in Rats: Neurological Assessment and Pet Imaging With 18 F-Fluorodeoxyglucaric Acid. bioRxiv (Cold Spring Harbor Laboratory) (2021)

Hibah O. AwwadAndria HedrickAlex MdzinarishviliHailey HousonKelly M. StandiferVibhudutta Awasthi

neurological assessmentneurosciencehemorrhagic shockneurologytraumatic brain injury

Therapeutic Potential of Nociceptin/Orphanin Fq Peptide (Nop) Receptor Modulators for Treatment of Traumatic Brain Injury, Traumatic Stress, and Their Co-Morbidities. Pharmacology & Therapeutics (2021)

Omar N. Al YacoubHibah O. AwwadYong ZhangKelly M. Standifer

receptorsmedicinereceptor modulatorsneurosciencepharmacologytherapeutic targetspeptide sciencetreatment effectsneuromodulation (medicine)drug discoverypeptidestreatment optionsneuropharmacologypeptide therapeuticsmedicinal researchtraumatic stressinflammationpharmacological researchtherapeutic potentialclinical pharmacologypharmacotherapytraumatic brain injury

Tnf-Alpha as an Initiator of Allodynia and Anxiety-Like Behaviors in a Preclinical Model of Ptsd and Comorbid Pain. Frontiers in Psychiatry (2021)

Patrick DibYong ZhangMichael A. IhnatRandle M. GallucciKelly M. Standifer

psychiatrymental healthanxiety-like behaviorspreclinical modelneurosciencepsychopathologybehavioral sciencescomorbid painpost-traumatic stress disorder

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Kelly M. Standifer

Professor and Chair

University of Oklahoma

Affiliations

HEALTH SCIENCES CENTER CAMPUS COLLEGES

College of Pharmacy

Health Sciences Center Graduate College

Kelly M. Standifer is currently serving as a College Of Pharmacy Professor and Chair at University of Oklahoma.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Kelly M. Standifer

University of Oklahoma

Professor and Chair

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Panini PatankarSoumyabrata MunshiOmar Al YacoubYong ZhangKelly Standifer

Testing the Effect of the Non-Selective Opioid Ppl-138 in a Model of Alcohol Relapse in the Context of Ptsd. Neuropharmacology (2025)

The Opioid Partial Agonist Ppl‐138 Reduces Alcohol Self‐Administration in Rats Susceptible to Post‐Traumatic Stress Disorder. British Journal of Pharmacology (2025)

Traumatic Brain Injury Induces Nociceptin/Orphanin Fq and Nociceptin Opioid Peptide Receptor Expression Within 24 Hours. International Journal of Molecular Sciences (2024)

Omar N. Al YacoubYong ZhangPanini S. PatankarKelly M. Standifer

receptorsneurochemistryneuropharmacologyneuroprotectionneurosciencepharmacologyphysiology

Recovery From Traumatic Brain Injury is Nociceptin/Orphanin Fq Peptide Receptor Genotype-, Sex-, and Injury Severity-Dependent. Journal of Pharmacology and Experimental Therapeutics (2023)

Omar N. Al YacoubHibah O. AwwadKelly M. Standifer

The Nociceptin/Orphanin Fq Peptide Receptor Antagonist, Sb-612111, Improves Cerebral Blood Flow in a Rat Model of Traumatic Brain Injury. Frontiers in Pharmacology (2023)

Omar N. Al YacoubStefano TarantiniYong ZhangAnna CsiszarKelly M. Standifer

cerebral blood flowreceptorsrat modelneuropharmacologyneurosciencepharmacologyneurologydrug discoverypharmacokineticspeptidestraumatic brain injury

Loss of Nociceptin/Orphanin Fq Peptide Receptor Protects Against Traumatic Brain Injury (Tbi)‐Induced Deficits in Male and Female Rats. The FASEB Journal (2021)

Omar Al YacoubMatthew BaierHibah AwwadKelly Standifer

receptorsneurochemistryneuropeptide receptorsneuropharmacologyneuroprotectionneurosciencepharmacologymammalian biologyneurologyfemale ratspeptidestraumatic brain injury

Modeling Traumatic Brain Injury Combined With Hemorrhagic Shock in Rats: Neurological Assessment and Pet Imaging With 18 F-Fluorodeoxyglucaric Acid. bioRxiv (Cold Spring Harbor Laboratory) (2021)

Hibah O. AwwadAndria HedrickAlex MdzinarishviliHailey HousonKelly M. StandiferVibhudutta Awasthi

neurological assessmentneurosciencehemorrhagic shockneurologytraumatic brain injury

Omar N. Al YacoubHibah O. AwwadYong ZhangKelly M. Standifer

Tnf-Alpha as an Initiator of Allodynia and Anxiety-Like Behaviors in a Preclinical Model of Ptsd and Comorbid Pain. Frontiers in Psychiatry (2021)

Patrick DibYong ZhangMichael A. IhnatRandle M. GallucciKelly M. Standifer

psychiatrymental healthanxiety-like behaviorspreclinical modelneurosciencepsychopathologybehavioral sciencescomorbid painpost-traumatic stress disorder

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5
9
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