Faculty

Institution

Unit

Venue

Andrei Karginov, PhD

Associate Professor

University of Illinois Chicago

Affiliations

College of Medicine of Chicago

Pharmacology and Regenerative Medicine

Andrei Karginov, Phd is currently serving as a College Of Medicine Of Chicago Associate Professor at University of Illinois Chicago.

Honors

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Experiences

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Education

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Andrei Karginov, PhD

University of Illinois Chicago

Associate Professor

You can click a keyword to filter the displayed items

cell biology cell signaling molecular biology signal transduction membrane biology physiology vascular biology cellular physiology neuroscience molecular cell biology cellular biochemistry protein engineering protein science signaling pathways angiogenesis cell regulation molecular regulation gene expression enzymes protein function protein phosphorylation molecular and cellular biology enzyme inhibition cellular biology cell motility medicinal research molecular physiology cell physiology cell migration light regulation living cells cell engineering mammalian biology catalyst activation allosteric activation specific src-effector complexes molecular cancer intracellular trafficking protein expression protein transport cancer biology endothelial barrier function engineered allosteric activation src family isoforms light-regulated allosteric switch phosphorylation-mediated regulation genome biology molecular science plant physiology cell research clinical biochemistry peptides protein bioinformatics cell trafficking cellular neurobiology cell biophysics functional modification insulin signaling colorectal cancer receptor (biochemistry) cell adhesion cutaneous biology human sciences cell interactions transcription regulation gene characterization toxinology pharmaceutical chemistry temporal regulation rational design src-dependent phosphorylation enzyme activity subcellular control endothelial permeability response novel activator dynamic regulation matrix biology synthetic biology systems biology extracellular matrix

Notable Scholarly Works

Notable Federal Grants

Collaborators

Abstract 2415 Tuning a Light-Regulated Allosteric Switch for Enhanced Temporal Control of Enzymes. Journal of Biological Chemistry (2025)

enzyme inhibitionlight-regulated allosteric switchstructure-function enzyme kineticsenzyme specificityenhanced temporal controlchemical biologyenzymesmolecular metabolismabstract 2415molecular biologybiological chemistryenzyme catalysisenzymatic modificationsignal transductioncellular enzymologycellular biochemistrybiochemistry

Abstract 2841 Development of an Engineered Light-Regulated Biotin Ligase for Interrogation of Protein Interactions With High Temporal Resolution. Journal of Biological Chemistry (2025)

biomolecular interactionsbiophysicsabstract 2841biomolecular toolsbiomolecular engineeringhigh temporal resolutionmolecular biologystructural molecular biologyprotein designprotein scienceprotein engineeringprotein interactions

Local Optogenetic Control of Genome Editing and Tumorigenesis in Vivo Using Wireless Implantable Optoelectronics. bioRxiv (Cold Spring Harbor Laboratory) (2025)

optogeneticslocal optogenetic controlgene editingbiomedical engineeringgenome editingcell manipulationsystems biologynature methodwireless implantable optoelectronicsgenome surgerybiomedical analysis

Development and Application of Rapamycin-Regulated Tyrosine Phosphatases. Journal of Visualized Experiments (2024)

signaling pathwaysenzyme inhibitionprotein phosphorylationreceptor tyrosine kinasesmolecular metabolismbiological chemistrysignal transductioncellular biochemistryrapamycin-regulated tyrosine phosphatasesbiochemistrybiosynthesis

Spatiotemporal Control of Protein Activity Through Optogenetic Allosteric Regulation. Journal of Visualized Experiments (2024)

optogeneticsmolecular regulationmolecular cell biologyfunctional regulationmolecular biologyprotein activitysignal transductioncellular regulatory mechanismcellular biochemistry

Dissecting Protein Tyrosine Phosphatase Signaling by Engineered Chemogenetic Control of Its Activity. The Journal of Cell Biology (2022)

Jordan FauserVincent HuyotJacob MatscheBarbara N. SzynalYuri AlexeevPradeep KotaAndrei V. Karginov

biomedical engineeringprotein tyrosine phosphataseprotein engineeringbiological engineeringcell biology

Engineered Allosteric Regulation of Protein Function. Journal of Molecular Biology (2022)

Jordan FauserNicholas LeschinskyBarbara N. SzynalAndrei V. Karginov

allosteric regulationprotein functionbiomolecular engineeringmolecular biologyprotein scienceprotein engineeringbiological engineering

FöRster Resonance Energy Transfer Biosensors for Fluorescence and Time-Gated Luminescence Analysis of Rac1 Activity. Scientific Reports (2022)

Ha PhamMona Hoseini SoflaeeAndrei V. KarginovLawrence W. Miller

biosensorsbiophysicstime-gated luminescence analysisscientific datafluorescenceneurosciencecell biology

Parallel Activation of Src and Hif1α Increases Localized Glycolytic Atp Generation for Re-Assembly of Endothelial Adherens Junctions. bioRxiv (Cold Spring Harbor Laboratory) (2022)

Li WangPriyanka GajwaniPallavi ChaturvediZhigang HongZijing YeGregory J. SchwarzNicole M. Pohl-AvilaAnne-Marie RaySarah KrantzPeter T TothDeborah E. LeckbandAndrei KarginovJalees Rehman

vascular barrier integritycellular physiologymetabolic remodelingparallel activationcell signalingvascular biologyprotein phosphorylationmolecular metabolismendothelial dysfunctionregional hypoxiametabolic pathwayssignal transductionmolecular physiologycell metabolismcellular biochemistrybiochemistrycell biology

Fret and Lret Biosensors for Cell-Based Imaging and Screening of Rac1 Activation. bioRxiv (Cold Spring Harbor Laboratory) (2021)

Ha PhamMona Hoseini SoflaeeAndrei V KarginovLawrence W. Miller

biosensorscell-based imagingbiomedical imagingophthalmologymolecular diagnosticsmolecular biologybiological imagingcell biologymolecular imaging

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Andrei Karginov, PhD

Associate Professor

University of Illinois Chicago

Affiliations

College of Medicine of Chicago

Pharmacology and Regenerative Medicine

Andrei Karginov, Phd is currently serving as a College Of Medicine Of Chicago Associate Professor at University of Illinois Chicago.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Andrei Karginov, PhD

University of Illinois Chicago

Associate Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Abstract 2415 Tuning a Light-Regulated Allosteric Switch for Enhanced Temporal Control of Enzymes. Journal of Biological Chemistry (2025)

Abstract 2841 Development of an Engineered Light-Regulated Biotin Ligase for Interrogation of Protein Interactions With High Temporal Resolution. Journal of Biological Chemistry (2025)

Local Optogenetic Control of Genome Editing and Tumorigenesis in Vivo Using Wireless Implantable Optoelectronics. bioRxiv (Cold Spring Harbor Laboratory) (2025)

optogeneticslocal optogenetic controlgene editingbiomedical engineeringgenome editingcell manipulationsystems biologynature methodwireless implantable optoelectronicsgenome surgerybiomedical analysis

Development and Application of Rapamycin-Regulated Tyrosine Phosphatases. Journal of Visualized Experiments (2024)

Spatiotemporal Control of Protein Activity Through Optogenetic Allosteric Regulation. Journal of Visualized Experiments (2024)

optogeneticsmolecular regulationmolecular cell biologyfunctional regulationmolecular biologyprotein activitysignal transductioncellular regulatory mechanismcellular biochemistry

Dissecting Protein Tyrosine Phosphatase Signaling by Engineered Chemogenetic Control of Its Activity. The Journal of Cell Biology (2022)

Jordan FauserVincent HuyotJacob MatscheBarbara N. SzynalYuri AlexeevPradeep KotaAndrei V. Karginov

biomedical engineeringprotein tyrosine phosphataseprotein engineeringbiological engineeringcell biology

Engineered Allosteric Regulation of Protein Function. Journal of Molecular Biology (2022)

Jordan FauserNicholas LeschinskyBarbara N. SzynalAndrei V. Karginov

allosteric regulationprotein functionbiomolecular engineeringmolecular biologyprotein scienceprotein engineeringbiological engineering

FöRster Resonance Energy Transfer Biosensors for Fluorescence and Time-Gated Luminescence Analysis of Rac1 Activity. Scientific Reports (2022)

Ha PhamMona Hoseini SoflaeeAndrei V. KarginovLawrence W. Miller

biosensorsbiophysicstime-gated luminescence analysisscientific datafluorescenceneurosciencecell biology

Parallel Activation of Src and Hif1α Increases Localized Glycolytic Atp Generation for Re-Assembly of Endothelial Adherens Junctions. bioRxiv (Cold Spring Harbor Laboratory) (2022)

Li WangPriyanka GajwaniPallavi ChaturvediZhigang HongZijing YeGregory J. SchwarzNicole M. Pohl-AvilaAnne-Marie RaySarah KrantzPeter T TothDeborah E. LeckbandAndrei KarginovJalees Rehman

Fret and Lret Biosensors for Cell-Based Imaging and Screening of Rac1 Activation. bioRxiv (Cold Spring Harbor Laboratory) (2021)

Ha PhamMona Hoseini SoflaeeAndrei V KarginovLawrence W. Miller

biosensorscell-based imagingbiomedical imagingophthalmologymolecular diagnosticsmolecular biologybiological imagingcell biologymolecular imaging

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6
10 / page

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Dolly Mehta, PhD

Institution

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endothelial cell biology

endothelial dysfunction

Steven Dudek

Institution

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pulmonary diseases

chronic obstructive pulmonary disease

Steven GONIAS

Institution

University of California, San Diego

urokinase receptor

protein science

Avraham Raz

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Shahid Baba

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Jeffrey Esko

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University of California, San Diego

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electrophysiology

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Rafael Fridman

Institution

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proteases

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Jianjie Ma

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cell biology

cellular physiology

Nicola C. Partridge

Institution

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parathyroid gland

pharmacological research