Faculty

Institution

Unit

Venue

Jong Yun

Associate Professor

Pennsylvania State University

Affiliations

Penn State College of Medicine

Department of Pharmacology

Jong Yun is currently serving as a Pharmacology Associate Professor at Pennsylvania State University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Jong Yun

Pennsylvania State University

Associate Professor

You can click a keyword to filter the displayed items

pharmacology cell biology enzyme inhibition immunology tumor biology oncology molecular biology cancer research medicinal research cell signaling cell death cancer biology therapeutic targets membrane biology drug discovery inflammation vascular biology leukemia anti-cancer agents cancer treatment molecular cancer protein science cancer cells cellular therapy oncogenes pharmacotherapy experimental pharmacology hematological malignancies apoptosis tumor targeting pharmacological research cellular physiology receptor tyrosine kinases molecular physiology clinical chemistry cancer immunosurveillance cell regulation molecular regulation experimental dermatology protein function angiogenesis inhibitory activity cell migration drug targeting myeloid neoplasia sphingosine kinase inhibitors acute myeloid leukemia autophagy biomolecular interactions lymphoid neoplasia hypoxia (medicine) cytokines cell biomechanics neurochemistry protein expression pharmaceutical chemistry transcription regulation cellular immune responses adult t-cell leukemia-lymphoma signaling pathways cancer cell migration sphingosine kinase inhibition regulatory role sphingosine kinase immune checkpoint inhibitors network models human sphingosine kinase cancer vaccine development t-lgl leukemia organic molecules intracellular imaging antitumor activity protein kinase stress-activated protein kinase novel therapeutic target acid ceramidase pathology neurology sphingosine kinases molecular neurodegeneration neuroimmunology

Notable Scholarly Works

Notable Federal Grants

Collaborators

Cannabinoid-Induced Immunogenic Cell Death of Colorectal Cancer Cells Through De Novo Synthesis of Ceramide is Partially Mediated by Cb2 Receptor. Cancers (2024)

Jeremy A. HengstVictor J. Ruiz-VelascoWesley M. Raup-KonsavageKent E. VranaJong K. Yun

pathologycarcinogenesischemoprevention strategiescancer discoverypharmacologytherapeutic targetscancer immunotherapypeptoidsinflammatory bowel diseaseoncogenesinhibitory activitymedicinal researchcolorectal cancer cellscellular therapycannabis usecancer riskmolecular gastroenterologyurologyimmune responses

Characterization of Anticancer Effects of the Analogs of Dj4, a Novel Selective Inhibitor of Rock and Mrck Kinases. Pharmaceuticals (2023)

Vijay Pralhad KaleJeremy A. HengstArati K. SharmaUpendarrao GollaSinisa DovatShantu G. AminJong K. YunDhimant H. Desai

drug developmentpharmaceutical sciencesanti-cancer agentscancer treatmentpharmaceuticsmedicinepharmacologydrug discoverypharmacotherapyenzyme inhibitionnovel selective inhibitoroncologypharmaceutical researchanticancer effects

Fanning the Flames of Endoplasmic Reticulum (Er) Stress: Can Sphingolipid Metabolism Be Targeted to Enhance Er Stress–Associated Immunogenic Cell Death in Cancer?. Molecular Pharmacology (2023)

Jeremy A. HengstAsvelt J. NduwumwamiArati SharmaJong K. Yun

cell deathstress (biology)endoplasmic reticulummolecular biologymolecular pharmacologyoncology

Regulatory Role of Sphingosine-1-Phosphate and C16: 0 Ceramide, in Immunogenic Cell Death of Colon Cancer Cells Induced by Bak/Bax-Activation. Cancers (2022)

Jeremy A. HengstAsvelt J. NduwumwamiJong K. Yun

tumor biologyimmunogenic cell deathcancer immunotherapycell deathimmunologybiochemistrycancer researchimmune responsesmucosal immunologymolecular biologycellular immune responsescancer immunosurveillancecolon cancer cellscancer cellsregulatory roleoncologycancer biology

Inhibition of Sphingosine Kinase Activity Enhances Immunogenic Cell Surface Exposure of Calreticulin Induced by the Synthetic Cannabinoid 5-Epi-Cp-55,940. Cannabis and Cannabinoid Research (2021)

Jeremy A. HengstAsvelt J. NduwumwamiWesley M. Raup-KonsavageKent E. VranaJong K. Yun

synthetic cannabinoidsphingosine kinase activityimmunologycannabis usepharmacologydrug discovery

Sphingosine Kinase Inhibition Enhances Dimerization of Calreticulin at the Cell Surface in Mitoxantrone-Induced Immunogenic Cell Death. Journal of Pharmacology and Experimental Therapeutics (2021)

Asvelt J. NduwumwamiJeremy A. HengstJong K. Yun

inflammationcell deathcell signalingimmunologycell biologycell metabolismexperimental pharmacologycellular immune responsessphingosine kinase inhibitionpharmacologytherapeutic targetscell surfacesignal transductionenzyme inhibitiontherapeutic efficacy

Analysis of Selective Target Engagement by Small-Molecule Sphingosine Kinase Inhibitors Using the Cellular Thermal Shift Assay (Cetsa). Cancer Biology & Therapy (2020)

Jeremy A. HengstTaryn E. DickCharles D. SmithJong K. Yun

small moleculesselective target engagementmolecular biologycancer biology

Development of Ski-349, a Dual-Targeted Inhibitor of Sphingosine Kinase and Microtubule Polymerization. Bioorganic & Medicinal Chemistry Letters (2020)

Jeremy A. HengstShailaja HegdeRobert F. PaulsonJong K. Yun

drug deliverypharmaceutical chemistrytumor targetingdrug targetingmedicinal chemistrysphingosine kinasebioorganic chemistryclinical chemistrydual-targeted inhibitormedicinepharmacologytherapeutic targetsdrug discoveryenzyme inhibitionbiomolecular engineeringmicrotubule polymerization

Mrck. Springer eBooks (2017)

Laura GeffertJong Yun

Ski-178: A Multitargeted Inhibitor of Sphingosine Kinase and Microtubule Dynamics Demonstrating Therapeutic Efficacy in Acute Myeloid Leukemia Models. Cancer translational medicine (2017)

Jeremy A HengstTaryn E DickArati SharmaKenichiro DoiShailaja HegdeSu-Fern TanLaura M GeffertTodd E FoxArun K SharmaDhimant DesaiShantu AminMark KesterThomas P LoughranRobert F PaulsonDavid F ClaxtonHong-Gang WangJong K Yun

radiation oncologymyeloid neoplasiatumor biologymicrotubule dynamicsmicrotubule disruptioncell deathcell signalingcell biologyhematological malignanciesmolecular cell biologyacute myeloid leukemiatherapeutic targetscancer cellscell regulationleukemiacancer biology

1
2
3
4
5
6
7
10 / page

Jong Yun

Associate Professor

Pennsylvania State University

Affiliations

Penn State College of Medicine

Department of Pharmacology

Jong Yun is currently serving as a Pharmacology Associate Professor at Pennsylvania State University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Jong Yun

Pennsylvania State University

Associate Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Cannabinoid-Induced Immunogenic Cell Death of Colorectal Cancer Cells Through De Novo Synthesis of Ceramide is Partially Mediated by Cb2 Receptor. Cancers (2024)

Jeremy A. HengstVictor J. Ruiz-VelascoWesley M. Raup-KonsavageKent E. VranaJong K. Yun

Characterization of Anticancer Effects of the Analogs of Dj4, a Novel Selective Inhibitor of Rock and Mrck Kinases. Pharmaceuticals (2023)

Vijay Pralhad KaleJeremy A. HengstArati K. SharmaUpendarrao GollaSinisa DovatShantu G. AminJong K. YunDhimant H. Desai

Fanning the Flames of Endoplasmic Reticulum (Er) Stress: Can Sphingolipid Metabolism Be Targeted to Enhance Er Stress–Associated Immunogenic Cell Death in Cancer?. Molecular Pharmacology (2023)

Jeremy A. HengstAsvelt J. NduwumwamiArati SharmaJong K. Yun

cell deathstress (biology)endoplasmic reticulummolecular biologymolecular pharmacologyoncology

Regulatory Role of Sphingosine-1-Phosphate and C16: 0 Ceramide, in Immunogenic Cell Death of Colon Cancer Cells Induced by Bak/Bax-Activation. Cancers (2022)

Jeremy A. HengstAsvelt J. NduwumwamiJong K. Yun

Inhibition of Sphingosine Kinase Activity Enhances Immunogenic Cell Surface Exposure of Calreticulin Induced by the Synthetic Cannabinoid 5-Epi-Cp-55,940. Cannabis and Cannabinoid Research (2021)

Jeremy A. HengstAsvelt J. NduwumwamiWesley M. Raup-KonsavageKent E. VranaJong K. Yun

synthetic cannabinoidsphingosine kinase activityimmunologycannabis usepharmacologydrug discovery

Sphingosine Kinase Inhibition Enhances Dimerization of Calreticulin at the Cell Surface in Mitoxantrone-Induced Immunogenic Cell Death. Journal of Pharmacology and Experimental Therapeutics (2021)

Asvelt J. NduwumwamiJeremy A. HengstJong K. Yun

Analysis of Selective Target Engagement by Small-Molecule Sphingosine Kinase Inhibitors Using the Cellular Thermal Shift Assay (Cetsa). Cancer Biology & Therapy (2020)

Jeremy A. HengstTaryn E. DickCharles D. SmithJong K. Yun

small moleculesselective target engagementmolecular biologycancer biology

Development of Ski-349, a Dual-Targeted Inhibitor of Sphingosine Kinase and Microtubule Polymerization. Bioorganic & Medicinal Chemistry Letters (2020)

Jeremy A. HengstShailaja HegdeRobert F. PaulsonJong K. Yun

Mrck. Springer eBooks (2017)

Laura GeffertJong Yun

Ski-178: A Multitargeted Inhibitor of Sphingosine Kinase and Microtubule Dynamics Demonstrating Therapeutic Efficacy in Acute Myeloid Leukemia Models. Cancer translational medicine (2017)

1
2
3
4
5
6
7
10 / page

Similar Faculty Members

Lee Graves

Institution

University of North Carolina at Chapel Hill

molecular biology

pharmacology

Donna Zhang

Institution

University of Arizona

toxicology

reactive oxygen specie

Ann Richmond, Ph.D

Institution

Vanderbilt University

immunology

molecular cancer

Dafna Bar-Sagi

Institution

New York University

oncogene

oncogene function

Shantu Amin

Institution

Pennsylvania State University

cancer letter

polycyclic aromatic hydrocarbon

Chellappan, Srikumar

Institution

University of South Florida

cell biology

tumor biology

Jonathan D Licht

Institution

University of Florida

oncology

pathology

Gary Johnson

Institution

University of North Carolina at Chapel Hill

mapk kinase

apoptosis

Jie Wu

Institution

University of Oklahoma

chronic pain

pediatrics

Said M. Sebti

Institution

Virginia Commonwealth University

receptor tyrosine kinase

molecular cancer

Similar Faculty Members

Lee Graves

Institution

University of North Carolina at Chapel Hill

molecular biology

pharmacology

Donna Zhang

Institution

University of Arizona

toxicology

reactive oxygen specie

Ann Richmond, Ph.D

Institution

Vanderbilt University

immunology

molecular cancer

Dafna Bar-Sagi

Institution

New York University

oncogene

oncogene function

Shantu Amin

Institution

Pennsylvania State University

cancer letter

polycyclic aromatic hydrocarbon

Chellappan, Srikumar

Institution

University of South Florida

cell biology

tumor biology

Jonathan D Licht

Institution

University of Florida

oncology

pathology

Gary Johnson

Institution

University of North Carolina at Chapel Hill

mapk kinase

apoptosis

Jie Wu

Institution

University of Oklahoma

chronic pain

pediatrics

Said M. Sebti

Institution

Virginia Commonwealth University

receptor tyrosine kinase

molecular cancer