Faculty

Institution

Unit

Venue

John Cunningham

George M Eisenberg Professor of Pediatrics

University of Chicago

Affiliations

Pediatrics, Department of

John Cunningham is currently serving as a Pediatrics, Department Of George M Eisenberg Professor of Pediatrics at University of Chicago.

Honors

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Experiences

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Education

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John Cunningham

University of Chicago

George M Eisenberg Professor of Pediatrics

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genetics hematology molecular biology gene expression medicine regenerative medicine developmental biology mammalian biology stem cell transplantation transplantation medicine epigenetics genome biology gene regulation genomics cell transplantation transcription regulation molecular genetics human genetics molecular physiology bone marrow transplantation cell regulation molecular regulation molecular and cellular biology medicinal research protein science clinical transplantation molecular cell biology pediatric transplantation developmental genetics cellular physiology cancer genetics vascular biology stem cell research protein genetics gene function cancer genomics stem-cell therapy protein expression cellular biology signaling pathways sickle cell disease leukemia biological chemistry hematological malignancies pediatric hematology genomic medicine cancer biology medical genetics cancer management high-risk neuroblastoma molecular cancer gene transfer knockout mice cancer treatment acute myeloid leukemia viral genetics biochemical genetics genetic factors metabolic regulation cutaneous biology immunohaematology angiogenesis cell therapy cardiac hypertrophy developmental transcription factors disease relapse durable remissions rapid engraftment gene silencing dna methylation igf-akt signaling membrane localization epidermal integrity enforced expression low gvhd reduced-intensity conditioning

Notable Scholarly Works

Notable Federal Grants

Collaborators

An Approach to Compensation Plans for Physician Faculty in Academic Pediatric Departments. The Journal of Pediatrics (2023)

Satyan LakshminrusimhaAnn M. ReedTina L. ChengJohn M. CunninghamSherin U. Devaskar

health policypediatricsmedical educationcompensation plansphysician faculty

Etv2 Primes Hematoendothelial Gene Enhancers Prior to Hematoendothelial Fate Commitment. Cell Reports (2023)

Jeffrey D. SteimleChul KimMegan RowtonRangarajan D. NadadurZhezhen WangMatthew StockerAndrew D. HoffmannErika HansonJunghun KweonTanvi SinhaKyunghee ChoiBrian L. BlackJohn M. CunninghamIvan P. MoskowitzKohta Ikegami

regenerative medicineimmunologycell biologyhematoendothelial gene enhancershematologymolecular biology

Detecting Critical Transition Signals From Single-Cell Transcriptomes to Infer Lineage-Determining Transcription Factors. Nucleic Acids Research (2022)

Xinan H YangAndrew GoldsteinYuxi SunZhezhen WangMegan WeiIvan P MoskowitzJohn M Cunningham

single-cell analysisfunctional genomicsbioinformaticsgeneticsepigeneticsgenomicsmolecular sciencemolecular biologygene expressionnucleic acidssingle-cell transcriptomescritical transition signalssystems biologytranscriptomics technologyrna biologygenome biologylineage-determining transcription factorsgenome analysissequence analysis

The Addition of Autologous Stem Cell Transplantation to Neoadjuvant Chemotherapy, Radiation, and Hipec for Patients With Unresectable Desmoplastic Small Round Cell Tumor: A Single Center Case Series. International Journal of Surgery Oncology (2020)

Amir SiddiquiNavin PintoMark A. ApplebaumGrace Z. MakJohn M. CunninghamJames L. LaBelleMichele L. Nassin

stem cellssurgical oncologysurgerycancer immunotherapystem-cell therapyneoadjuvant chemotherapycancer researchcancer treatmentmedical mycologyradiation oncologynanomedicinecancer managementcancer careradiation therapycell transplantationmedicineclinical transplantationstem cell transplantationoncology

Outcomes Following Second Allogeneic Stem Cell Transplant for Disease Relapse After T Cell Depleted Transplant Correlate With Remission Status and Remission Duration After the First Transplant. Experimental Hematology and Oncology (2019)

Yun FanAndrew S. ArtzKoen van BesienWendy StockRichard A. LarsonOlatoyosi OdenikeLucy A. GodleyJustin KlineJohn M. CunninghamJames L. LaBelleMichael R. BishopHongtao Liu

disease relapseimmunologybone marrow transplantationtransplantation medicineorgan transplantationstem-cell therapyhematologyremission durationoutcomes researchremission statushealth sciencescell therapyfirst transplantliver transplantationregenerative medicinecell transplantationhematological malignanciesmedicineclinical transplantationexperimental medicinestem cell transplantationoncology

Tipping-Point Analysis Uncovers Critical Transition Signals From Gene Expression Profiles. bioRxiv (Cold Spring Harbor Laboratory) (2019)

Xinan H YangZhezhen WangAndrew GoldsteinYuxi SunMegan RowtonYanqiu WangDannie GriggsIvan MoskowitzJohn M Cunningham

gene expression profilesfunctional genomicsepigenomicsmolecular biologysystems biology

Abstract 411: Risk-Dependent Enhancer Transcription Defines Oncogenic Gene Regulatory Networks for High-Risk Neuroblastoma. Cancer Research (2018)

Zhezhen WangIvan P. MoskowitzJohn M. CunninghamXinan Holly Yang

cancer biologyhigh-risk neuroblastomagene regulationcancer researchrisk-dependent enhancer transcriptioncancer geneticscancer genomicsoncologygenetics

CISPI: A Transcriptomic Score for Disclosing Cis-Acting Disease-Associated Lincrnas. Bioinformatics (2018)

Zhezhen WangJohn M CunninghamXinan H Yang

informaticstranslational bioinformaticscomputational biologyhealth informaticsbiomedical informaticsgenome analysisrna biologysequence analysisgenomicsmolecular biologydata sciencetranscriptomic scorecis-acting disease-associated lincrnastranscriptomics technologyhealth sciencesbioinformaticsgenome biology

A C-Myc-Regulated Stem Cell-Like Signature in High-Risk Neuroblastoma: A Systematic Discovery (Target Neuroblastoma Esc-Like Signature). Scientific Reports (2017)

Xinan YangFangming TangJisu ShinJohn M. Cunningham

systematic discoveryhigh-risk neuroblastomastem cellsgenetics

Autologous Stem Cell Transplantation Added to Standard Chemotherapy, Hipec Surgery, and Whole Abdominal Radiation is Well Tolerated and May Increases Progression Free Survival in Patients With Desmoplastic Small Round Cell Tumors. Biology of Blood and Marrow Transplantation (2017)

Michele L. NassinHillary M. HecktmanCaitlin CohenGabrielle Lapping-CarrNavin R. PintoJohn M. CunninghamJames L. LaBelle

radiation therapyradiation oncologytumor biologycell transplantationhematologybone marrow transplantationprogression free survivalbiomedical engineeringcancer researchmedicinehipec surgerycancer managementcancer treatmentcancer careoncologywhole abdominal radiationtransplantation medicine

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John Cunningham

George M Eisenberg Professor of Pediatrics

University of Chicago

Affiliations

Pediatrics, Department of

John Cunningham is currently serving as a Pediatrics, Department Of George M Eisenberg Professor of Pediatrics at University of Chicago.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

John Cunningham

University of Chicago

George M Eisenberg Professor of Pediatrics

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

An Approach to Compensation Plans for Physician Faculty in Academic Pediatric Departments. The Journal of Pediatrics (2023)

Satyan LakshminrusimhaAnn M. ReedTina L. ChengJohn M. CunninghamSherin U. Devaskar

health policypediatricsmedical educationcompensation plansphysician faculty

Etv2 Primes Hematoendothelial Gene Enhancers Prior to Hematoendothelial Fate Commitment. Cell Reports (2023)

regenerative medicineimmunologycell biologyhematoendothelial gene enhancershematologymolecular biology

Detecting Critical Transition Signals From Single-Cell Transcriptomes to Infer Lineage-Determining Transcription Factors. Nucleic Acids Research (2022)

Xinan H YangAndrew GoldsteinYuxi SunZhezhen WangMegan WeiIvan P MoskowitzJohn M Cunningham

Amir SiddiquiNavin PintoMark A. ApplebaumGrace Z. MakJohn M. CunninghamJames L. LaBelleMichele L. Nassin

Yun FanAndrew S. ArtzKoen van BesienWendy StockRichard A. LarsonOlatoyosi OdenikeLucy A. GodleyJustin KlineJohn M. CunninghamJames L. LaBelleMichael R. BishopHongtao Liu

Tipping-Point Analysis Uncovers Critical Transition Signals From Gene Expression Profiles. bioRxiv (Cold Spring Harbor Laboratory) (2019)

Xinan H YangZhezhen WangAndrew GoldsteinYuxi SunMegan RowtonYanqiu WangDannie GriggsIvan MoskowitzJohn M Cunningham

gene expression profilesfunctional genomicsepigenomicsmolecular biologysystems biology

Abstract 411: Risk-Dependent Enhancer Transcription Defines Oncogenic Gene Regulatory Networks for High-Risk Neuroblastoma. Cancer Research (2018)

Zhezhen WangIvan P. MoskowitzJohn M. CunninghamXinan Holly Yang

cancer biologyhigh-risk neuroblastomagene regulationcancer researchrisk-dependent enhancer transcriptioncancer geneticscancer genomicsoncologygenetics

CISPI: A Transcriptomic Score for Disclosing Cis-Acting Disease-Associated Lincrnas. Bioinformatics (2018)

Zhezhen WangJohn M CunninghamXinan H Yang

A C-Myc-Regulated Stem Cell-Like Signature in High-Risk Neuroblastoma: A Systematic Discovery (Target Neuroblastoma Esc-Like Signature). Scientific Reports (2017)

Xinan YangFangming TangJisu ShinJohn M. Cunningham

systematic discoveryhigh-risk neuroblastomastem cellsgenetics

Michele L. NassinHillary M. HecktmanCaitlin CohenGabrielle Lapping-CarrNavin R. PintoJohn M. CunninghamJames L. LaBelle

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