Faculty

Institution

Unit

Venue

Amittha Wickrema

Professor of Medicine

University of Chicago

Affiliations

Pritzker School of Medicine

Medicine

Medicine, Department of

Amittha Wickrema is currently serving as a Medicine Professor of Medicine at University of Chicago.

Honors

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Experiences

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Education

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Amittha Wickrema

University of Chicago

Professor of Medicine

You can click a keyword to filter the displayed items

hematology medicine immunology genetics cell biology oncology gene expression regenerative medicine medicinal research transplantation medicine cell transplantation stem cell research cell signaling clinical transplantation membrane biology leukemia hematological malignancies tumor biology hepatology cellular therapy stem cell transplantation hemostasis bone marrow transplantation mammalian biology cancer biology cell regulation protein science biological chemistry oncogenes enzyme inhibition liver physiology cancer genetics lymphoid neoplasia blood cells cell therapy cellular physiology molecular physiology molecular cell biology myelopoiesis rna biology gene function myelodysplastic syndromes transcription regulation apoptosis signaling pathways cancer treatment cytokines stem-cell therapy host factors cancer genomics host specificity cytogenetics erythroblast enucleation multiple myeloma clinical medicine redox signaling adaptive immune system molecular regulation innate immune system gene regulation tumor targeting cancer growth stem cell factor erythroid progenitor cells myelodysplastic syndrome human erythroblasts advanced hematologic malignancies phase i-ii study functional modification reduced-intensity conditioning tgf-b signaling acute myeloid leukemia hematologic malignancies prospective study mature erythrocytes aml stem cells

Notable Scholarly Works

Notable Federal Grants

Collaborators

Chromatin Rewiring of β-Globin and Myc Enhancers by Tgf-β1 Drives Defective Erythropoiesis. Nature Communications (2026)

epigeneticsgeneticshaematopoiesischromatinchromatin remodelingcell biologymolecular cell biologytranscription factors

3043 – Suppression of Tet2 Activity Leads to Increased Expression of Fetal Hemoglobin in Adult Erythroblasts. Experimental Hematology (2025)

hematologycellular differentiationhaematopoiesiscell biologyheme homeostasiscell research

Enrichment of Cd4+ and Cd8+ T Lymphocytes With a Column-Free Flow-Based Device for Clinical Cell Manufacturing. Cytotherapy (2025)

Paulina LangaKriti SharmaDavid L SellersVeronica PlacenciaEric A. SmithDan FickJohn R. WilsonSilin SaNathaniel OrtegaLiping YuYuchen ZhouIgnacio NunezAmittha Wickrema

cellular therapycell therapycell biologycolumn-free flowclinical cell manufacturing

Splicing of Erythroid Transcription Factor is Associated With Therapeutic Response in Myelodysplastic Syndromes. Journal of Clinical Investigation (2025)

hematologygeneticshaematopoiesiscell biologyleukemiamolecular cell biologysplicing varianttranscription factorsgene expressionpathology

Supplementary Table S1 From Elevated Clonal Hematopoiesis in 9/11 First Responders Has Distinct Age-Related Patterns and Relies on Il1Rap for Clonal Expansion. (2025)

hematologyimmune responseshaematopoiesisleukemiaimmunologycell transplantationmyelopoiesispathology

3020 – Splicing of a Master Erythroid Transcription Factor Governs Therapeutic Targeting of Anemia in Mds. Experimental Hematology (2024)

Srinivas AluriTe LingEllen FraintSamarpana ChakrabortyKevin ZhangAarif AhsanGowri PoigaialwarRongbao ZhaoKith PradhanAnitria CottonKimo BachiashvilliAnjali BudhathokiBeamon AggarwalShanisha GordonMilagros CarbajalSrabani SahuJung-In YangJacqueline BoultwoodAndrea PellagatiUlrich SteidlAmittha WickremaSatish NandakumarRajasekhar SuraganiAditi ShastriTeresa BowmanJohn Crispinovodala sadanandAmit Verma

hematologyhematological malignanciesnovel therapiestherapeutic targetingsplicing varianttranscription factorsexperimental medicinehealth sciences

3056 – Sustained Expression of Cxcr4 in a Sub-Population of Cells Defines the Basis of Heterogeneous Erythropoietin Sensitivity in Developing Red Blood Cells. Experimental Hematology (2024)

Trinath DasMatthew HorchHui LiuJeong jongAndrew ArtzAmittha Wickrema

hematologyblood cellsimmunologyheterogeneous erythropoietin sensitivityred blood cells

Tgf-β1-Smad2 Axis Regulates Hematopoiesis and β-Globin Gene Expression via Super-Enhancer Associated Chromatin Reorganization. Blood (2024)

Srinivas AluriKimo BachiashviliAnjali BudhathokiJong J JeongShanisha Gordon MitchellMilagros CarbajalSamarpana ChakrabortySanjay PandeyMahinder Paul WadhwaSrabani SahuJung-In YangGaurav S ChoudharyTushar Damodar BhagatNandini RamachandraRongbao ZhaoBianca RiveraRitesh AggarwalKith PradhanShahina MaqboolSeong jin KimSunjin HwangUlrich SteidlAditi ShastriMarc RaaijmakersAndrea PellagattiJacqueline BoultwoodAmittha WickremaAmit Verma

hematologyb-globin gene expressiongene expressionblood cellshaematopoiesischromatinchromatin reorganizationmolecular biology

The Demise of Islet Allotransplantation in the United States: A Call for an Urgent Regulatory Update. UNC Libraries (2024)

translational researchmedicinepancreas transplantationtransplantation proceeding

Data From Pu.1-Dependent Enhancer Inhibition Separates I Tet2 /I -Deficient Hematopoiesis From Malignant Transformation. (2023)

Maria M. AivaliotiBoris A. BartholdyKith PradhanTushar D. BhagatAliona ZintiridouJong Jin JeongVictor J. ThiruthuvanathanMario PujatoAditi ParanjpeChi ZhangRoss L. LevineAaron D. VinyAmittha WickremaAmit VermaBritta Will

hepatologyhematologytumor biologygeneticsoncologyhaematopoiesismolecular cancerhematological malignanciescancer growthliver canceroncogenic agentpharmacologymalignant transformationmolecular biologycancer genetics

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Amittha Wickrema

Professor of Medicine

University of Chicago

Affiliations

Pritzker School of Medicine

Medicine

Medicine, Department of

Amittha Wickrema is currently serving as a Medicine Professor of Medicine at University of Chicago.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Amittha Wickrema

University of Chicago

Professor of Medicine

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Chromatin Rewiring of β-Globin and Myc Enhancers by Tgf-β1 Drives Defective Erythropoiesis. Nature Communications (2026)

epigeneticsgeneticshaematopoiesischromatinchromatin remodelingcell biologymolecular cell biologytranscription factors

3043 – Suppression of Tet2 Activity Leads to Increased Expression of Fetal Hemoglobin in Adult Erythroblasts. Experimental Hematology (2025)

hematologycellular differentiationhaematopoiesiscell biologyheme homeostasiscell research

Enrichment of Cd4+ and Cd8+ T Lymphocytes With a Column-Free Flow-Based Device for Clinical Cell Manufacturing. Cytotherapy (2025)

Paulina LangaKriti SharmaDavid L SellersVeronica PlacenciaEric A. SmithDan FickJohn R. WilsonSilin SaNathaniel OrtegaLiping YuYuchen ZhouIgnacio NunezAmittha Wickrema

cellular therapycell therapycell biologycolumn-free flowclinical cell manufacturing

Splicing of Erythroid Transcription Factor is Associated With Therapeutic Response in Myelodysplastic Syndromes. Journal of Clinical Investigation (2025)

hematologygeneticshaematopoiesiscell biologyleukemiamolecular cell biologysplicing varianttranscription factorsgene expressionpathology

Supplementary Table S1 From Elevated Clonal Hematopoiesis in 9/11 First Responders Has Distinct Age-Related Patterns and Relies on Il1Rap for Clonal Expansion. (2025)

hematologyimmune responseshaematopoiesisleukemiaimmunologycell transplantationmyelopoiesispathology

3020 – Splicing of a Master Erythroid Transcription Factor Governs Therapeutic Targeting of Anemia in Mds. Experimental Hematology (2024)

hematologyhematological malignanciesnovel therapiestherapeutic targetingsplicing varianttranscription factorsexperimental medicinehealth sciences

3056 – Sustained Expression of Cxcr4 in a Sub-Population of Cells Defines the Basis of Heterogeneous Erythropoietin Sensitivity in Developing Red Blood Cells. Experimental Hematology (2024)

Trinath DasMatthew HorchHui LiuJeong jongAndrew ArtzAmittha Wickrema

hematologyblood cellsimmunologyheterogeneous erythropoietin sensitivityred blood cells

Tgf-β1-Smad2 Axis Regulates Hematopoiesis and β-Globin Gene Expression via Super-Enhancer Associated Chromatin Reorganization. Blood (2024)

hematologyb-globin gene expressiongene expressionblood cellshaematopoiesischromatinchromatin reorganizationmolecular biology

The Demise of Islet Allotransplantation in the United States: A Call for an Urgent Regulatory Update. UNC Libraries (2024)

translational researchmedicinepancreas transplantationtransplantation proceeding

Data From Pu.1-Dependent Enhancer Inhibition Separates I Tet2 /I -Deficient Hematopoiesis From Malignant Transformation. (2023)

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5
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University of Pennsylvania

developmental biology

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Stephen D. Nimer

Institution

University of Miami

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Jonathan D Licht

Institution

University of Florida

oncology

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Mary Kay Washington, Ph.D., M.D

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molecular medicine