Faculty

Institution

Unit

Venue

Jianguo Tao

Professor of Pathology

University of Virginia

Affiliations

School of Medicine

Department of Pathology

Jianguo Tao is currently serving as a Pathology Professor of Pathology at University of Virginia.

Honors

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Experiences

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Education

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Jianguo Tao

University of Virginia

Professor of Pathology

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cancer cells cell biology immunology tumor biology lymphoid neoplasia oncogenes leukemia cancer research molecular cancer hematological malignancies therapeutic targets oncology radiation oncology cancer biology mantle cell lymphoma cell death immune responses tumor microenvironment cellular therapy cell signaling medicinal research immune checkpoint inhibitors microrna detection molecular medicine anti-cancer agents pharmacology molecular cell biology cancer discovery myeloid neoplasia malignant blood disorders molecular diagnostics cancer immunosurveillance apoptosis epigenetic changes cancer care receptor tyrosine kinases cell regulation adult t-cell leukemia-lymphoma aggressive b-cell lymphomas tumor suppressors bone marrow transplantation immunologic mechanisms signaling pathways cancer genetics cancer treatment lymphoma cells cellular immune responses cancer growth epigenomics novel therapies malignant disease bone marrow histopathology cell transplantation chemoprevention strategies multiple myeloma novel therapeutic strategy selective bromodomain inhibitor autophagy antiviral research myelopoiesis cell cycle cytokines immune dysregulation molecular immunology cell adhesion biological microenvironments mds patients mdsc expansion -refractory human leukemia cell cycle g mutant bcr-abl inhibitor laq824 apo-2l/trail-induced apoptosis b cell leukemia murine cll model

Notable Scholarly Works

Notable Federal Grants

Collaborators

Targeting Persister Cells: Proactively Overcoming Therapy Resistance in Aggressive B Cell Lymphomas. Trends in cancer (2026)

immunologyhematological malignanciesimmune checkpoint inhibitorslymphoid neoplasiacell researchtherapeutic targetstherapy resistanceimmune responsescancer cellspersister cellscellular therapyimmunotherapycell biology

Abstract 5364: Multi-Omic Analyses Reveal Epigenetic and Transcriptomic Reprogramming Behind Ibrutinib-Venetoclax Resistance Development in Mantle Cell Lymphoma. Cancer Research (2025)

Kevin QiuJing GaoQing YinAllen HuZhenjia WangLoryn BlackburnBijal ShahJeffrey W. CraigCraig PortellMichael E. WilliamsChongzhi ZangJianguo Tao

ibrutinib-venetoclax resistance developmenttranscriptomic reprogrammingmantle cell lymphomacancer researchmulti-omics studiesmulti-omic analysesepigenetics

Overcoming Therapy Resistance With Multi-Targeted Car-T Cells Secreting Bispecific Antibody (Bsab) for the Treatment of B-Cell Malignancies. Blood (2025)

immunologyimmune checkpoint inhibitorscancer immunotherapytherapy resistancebispecific antibodyantibody engineeringmulti-targeted car-t cellscancer cellsimmunomodulationcellular therapyimmunotherapycell biology

Synergistic Vulnerability of Aggressive B-Cell Lymphoma to Combined MCL-1 Inhibition and Car-T Cell Therapy. Blood (2025)

immunologyhematological malignanciesleukemiaaggressive b-cell lymphomaimmune checkpoint inhibitorslymphoid neoplasiasynergistic vulnerabilitymcl-1 inhibitioncancer immunotherapytherapeutic targetsoncogenescancer cellscellular therapyimmunotherapycell biology

Transcriptional Condensates: Epigenetic Reprogramming and Therapeutic Targets in Hematologic Malignancies. Cancers (2025)

hematological malignanciesleukemiaepigenomicsradiation oncologytranscription (biology)epigenetic changesoncogenescancer cellsepigeneticschromatin remodelingtranscriptional condensateschromatincell biology

Combinatorial Therapy of Cdk9 Inhibitor With Cd19 Car-T to Reciprocally Overcome Therapy Resistance and Enhance Treatment Efficacies Against Aggressive B-Cell Lymphomas. Blood (2024)

Qing YinMichelle WangAllen HuJing GaoDanielle C LlanezaLoryn L BlackburnJeffrey W CraigBijal D ShahCraig A. PortellMichael E WilliamsJianguo Tao

treatment developmentnovel therapiesanti-cancer agentsaggressive b-cell lymphomastreatment efficaciescancer researchlymphoid neoplasiatherapeutic targetscancer immunotherapycancer treatmenttumor biologyimmunologyenzyme inhibitionpharmacologybiomedical engineeringpharmacotherapycombinatorial therapyoncologyoncogenesmedicinal researchcellular therapy

Concurrent Involvement of the Bone Marrow by Braf V600E–Mutant Melanoma and Hairy Cell Leukemia. Journal of Hematopathology (2024)

Margaret MoorePranav PatelJianguo Tao

immunologyhematological malignanciesleukemiamelanomahematologycancer researchmalignant diseaseconcurrent involvementbone marrow transplantationmalignant blood disordersbone marrowcancer biologypathologyhairy cell leukemia

Dysregulation of Transcription Machinery Drives the Acquisition of Btk Inhibitor and Venetoclax Treatment Resistance in Mantle Cell Lymphoma. Blood (2024)

Jing GaoKevin QiuKallesh Danappa JayappaQing YinMichelle WangAllen HuDanielle C LlanezaLoryn L BlackburnJeffrey W CraigBijal D ShahCraig A. PortellMichael E WilliamsChongzhi ZangJianguo Tao

transcription machinerytranscription regulationmantle cell lymphomahematologybtk inhibitormolecular biologyvenetoclax treatment resistance

Data From Prdm1 is Required for Mantle Cell Lymphoma Response to Bortezomib. (2023)

Shruti DesaiMichelle MaurinMatthew A. SmithSophia C.E. BolickSophie DessureaultJianguo TaoEduardo SotomayorKenneth L. Wright

immunologydermatologyhematology

Exploiting the Fibroblast Growth Factor Receptor-1 Vulnerability to Therapeutically Restrict the Myc-Ezh2-Cdkn1C Axis-Driven Proliferation in Mantle Cell Lymphoma. Leukemia (2023)

Anuvrat SircarSatishkumar SinghZijun Y. Xu-MonetteKrysta Mila CoyleLaura K. HiltonEvangelia ChavdoulaParvathi RanganathanNeeraj JainWalter HanelPhilip TsichlisLapo AlinariBlake R. PetersonJianguo TaoNatarajan MuthusamyRobert BaiocchiNarendranath EpperlaKen H. YoungRyan MorinLalit Sehgal

hematological malignanciesmedicinecancer caremolecular cancercell proliferationfibroblast growth factorsleukemiacancer researchlymphoid neoplasiacancer immunotherapycancer growthtumor biologyimmunotherapyimmunologypharmacologymantle cell lymphomaoncologymedicinal researchcellular therapy

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Jianguo Tao

Professor of Pathology

University of Virginia

Affiliations

School of Medicine

Department of Pathology

Jianguo Tao is currently serving as a Pathology Professor of Pathology at University of Virginia.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Jianguo Tao

University of Virginia

Professor of Pathology

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Targeting Persister Cells: Proactively Overcoming Therapy Resistance in Aggressive B Cell Lymphomas. Trends in cancer (2026)

Abstract 5364: Multi-Omic Analyses Reveal Epigenetic and Transcriptomic Reprogramming Behind Ibrutinib-Venetoclax Resistance Development in Mantle Cell Lymphoma. Cancer Research (2025)

Kevin QiuJing GaoQing YinAllen HuZhenjia WangLoryn BlackburnBijal ShahJeffrey W. CraigCraig PortellMichael E. WilliamsChongzhi ZangJianguo Tao

ibrutinib-venetoclax resistance developmenttranscriptomic reprogrammingmantle cell lymphomacancer researchmulti-omics studiesmulti-omic analysesepigenetics

Overcoming Therapy Resistance With Multi-Targeted Car-T Cells Secreting Bispecific Antibody (Bsab) for the Treatment of B-Cell Malignancies. Blood (2025)

Synergistic Vulnerability of Aggressive B-Cell Lymphoma to Combined MCL-1 Inhibition and Car-T Cell Therapy. Blood (2025)

Transcriptional Condensates: Epigenetic Reprogramming and Therapeutic Targets in Hematologic Malignancies. Cancers (2025)

Combinatorial Therapy of Cdk9 Inhibitor With Cd19 Car-T to Reciprocally Overcome Therapy Resistance and Enhance Treatment Efficacies Against Aggressive B-Cell Lymphomas. Blood (2024)

Qing YinMichelle WangAllen HuJing GaoDanielle C LlanezaLoryn L BlackburnJeffrey W CraigBijal D ShahCraig A. PortellMichael E WilliamsJianguo Tao

Concurrent Involvement of the Bone Marrow by Braf V600E–Mutant Melanoma and Hairy Cell Leukemia. Journal of Hematopathology (2024)

Margaret MoorePranav PatelJianguo Tao

Dysregulation of Transcription Machinery Drives the Acquisition of Btk Inhibitor and Venetoclax Treatment Resistance in Mantle Cell Lymphoma. Blood (2024)

Jing GaoKevin QiuKallesh Danappa JayappaQing YinMichelle WangAllen HuDanielle C LlanezaLoryn L BlackburnJeffrey W CraigBijal D ShahCraig A. PortellMichael E WilliamsChongzhi ZangJianguo Tao

transcription machinerytranscription regulationmantle cell lymphomahematologybtk inhibitormolecular biologyvenetoclax treatment resistance

Data From Prdm1 is Required for Mantle Cell Lymphoma Response to Bortezomib. (2023)

Shruti DesaiMichelle MaurinMatthew A. SmithSophia C.E. BolickSophie DessureaultJianguo TaoEduardo SotomayorKenneth L. Wright

immunologydermatologyhematology

Exploiting the Fibroblast Growth Factor Receptor-1 Vulnerability to Therapeutically Restrict the Myc-Ezh2-Cdkn1C Axis-Driven Proliferation in Mantle Cell Lymphoma. Leukemia (2023)

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4
5
12
10 / page

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