Faculty

Institution

Unit

Venue

James Conway

Professor

University of Pittsburgh

Affiliations

Medicine

Structural Biology

James Conway is currently serving as a Medicine Professor at University of Pittsburgh.

Honors

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Experiences

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Education

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James Conway

University of Pittsburgh

Professor

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virology molecular biology structural biology biophysics microbiology bacteriophages virus research protein structure microscopy viral genetics general virology virus structure phage biology structural molecular biology genetics viral evolution bacteriology gene expression virus-host interactions viral structural protein protein science biomolecular structure nanotechnology electron microscopy cryo-electron microscopy membrane biology protein assembly nanobiotechnology nanomedicine avian biology molecular virology nanoparticle research medicinal research sequence assembly microbial genetics mitochondrial function molecular structure vascular biology antiviral therapy drug targeting arbovirus molecular microbiology biomineralization viral hepatitis cryogenics dna packaging transmission electron microscopy cryoelectron microscopy biological chemistry enzyme inhibition medical virology science advance molecular cell biology cancer biology radiation biology antiviral drug development viral diagnostics pharmaceutical nanotechnology tumor targeting x-ray crystallography protein chemistry antibody engineering protein function virus maturation cryoelectron micrographs viral capsid radiation damage herpes simplex virus herpesvirus capsids dodecahedral penton particle different antibodies viral capsids genome release environmental microbiology capsid protein virus structural transitions virus capsids

Video Presentations

Notable Scholarly Works

Notable Federal Grants

Collaborators

Myxococcus Xanthus Encapsulin Cargo Protein Encd is a Flavin-Binding Protein With Ferric Reductase Activity. Proceedings of the National Academy of Sciences (2024)

Elif ErenNorman R. WattsJames F. ConwayPaul T. Wingfield

gene expressionprotein functionprotein structureflavin-binding proteinmolecular biologyhost-guest chemistrystructural biologyprotein sciencemicrobiologyferric reductase activitycell biology

Inhibition of Irhom1 by Cd44-Targeting Nanocarrier for Improved Cancer Immunochemotherapy. Nature Communications (2024)

Zhangyi LuoYixian HuangNeelu BatraYuang ChenHaozhe HuangYifei WangZiqian ZhangShichen LiChien-Yu ChenZehua WangJingjing SunQiming Jane WangDa YangBinfeng LuJames F. ConwayLu-Yuan LiAi-Ming YuSong Li

immunologytumor targetingnanobiotechnologyenzyme inhibitionpharmacologynanomedicinenanoparticle researchcancer immunotherapyoncologydrug targetingmedicinal researchcancer biologynanotechnologyimmunotherapy

Pneumococcal Extracellular Vesicles Mediate Horizontal Gene Transfer via the Transformation Machinery. mSphere (2024)

Sarah Werner LassBailey E. SmithShaw CamphireRory A. EutseyJojo A. PrenticeSaigopalakrishna S. YerneniAshni ArunAndrew A. BridgesJason W. RoschJames F. ConwayPhil CampbellN. Luisa Hiller

transformation machineryepidemiologymolecular and cellular biologyhorizontal gene transferpneumococcal extracellular vesiclesmolecular biologymicrobiology

Structural Basis of Deoxynucleotide Addition by Hiv-1 Rt During Reverse Transcription. Nature Communications (2024)

Sandra VergaraXiaohong ZhouUlises SantiagoMounia Alaoui-El-AzherJames F. ConwayNicolas Sluis-CremerGuillermo Calero

gene therapygeneral virologyhivantiviral researchkey siteviral geneticsstructural biologyprotein sciencereverse transcriptionvirus structuretranscription (biology)human retrovirusviral structural proteinstructural basisdeoxynucleotide additionimmunologyvirus researchgene expressionsystems biologymolecular biologystructural molecular biology

Structure of Biofilm-Forming Functional Amyloid Psmα1 From Staphylococcus Aureus. Proceedings of the National Academy of Sciences (2024)

Kasper Holst HansenChang Hyeock ByeonQian LiuTaner DraceThomas BoesenJames F. ConwayMaria AndreasenÜmit Akbey

biofilmsmicrobiology

A Structural Dendrogram of the Actinobacteriophage Major Capsid Proteins Provides Important Structural Insights Into the Evolution of Capsid Stability. Structure (2023)

Jennifer M. PodgorskiKrista FreemanSophia GosselinAlexis HuetJames F. ConwayMary BirdJohn GreccoShreya PatelDeborah Jacobs-SeraGraham HatfullJohann Peter GogartenJanne RavanttiSimon J. White

capsid stabilityprotein structurestructural dendrogramstructural biologymicrobiologyevolutionary biology

A Symmetry Mismatch Unraveled: How Phage Hk97 Scaffold Flexibly Accommodates a 12-Fold Pore at a 5-Fold Viral Capsid Vertex. Science Advances (2023)

Alexis HuetBonnie OhJosh MaurerRobert L. DudaJames F. Conway

virus researchbiophysicssymmetry mismatchvirus-host interactionsavian biologyphage biologyviral geneticsbacteriophagesvirologyscience advancemolecular biologyviral evolutionstructural biologymicrobiology

Insights Into a Viral Motor: The Structure of the Hk97 Packaging Termination Assembly. Nucleic Acids Research (2023)

Dorothy E D P HawkinsOliver W BayfieldHerman K H FungDaniel N GrbaAlexis HuetJames F ConwayAlfred A Antson

viral motorvirologymolecular biologysequence assemblystructural biology

Ionic Liquid-Coated Lipid Nanoparticles Increase Sirna Uptake Into Cns Targets. Nanoscale Advances (2023)

Purva KhareSara X. EdgecombChristine M. HamadaniJames F. ConwayEden E. L. TannerDevika S Manickam

nanobiotechnologymaterials sciencenanomedicinenanoscale sciencenanoscale chemistrycns targetsnanoparticle researchbiomolecular engineeringmolecular biologynanomaterialsnanotechnology

Structures of Kinetic Intermediate States of Hiv-1 Reverse Transcriptase Dna Synthesis. bioRxiv (Cold Spring Harbor Laboratory) (2023)

Sandra VergaraXiahong ZhouUlises SantiagoJames F ConwayNicolas Sluis-CremerGuillermo Calero

general virologyhivmolecular virologyviral geneticsenzymesbiomolecular structurestructural biologyprotein sciencemicrobial pathogenesisvirus structurekinetic intermediate stateshuman retrovirusviral structural proteinimmunologyvirus researchpharmacologyvirologymolecular biologystructural molecular biology

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James Conway

Professor

University of Pittsburgh

Affiliations

Medicine

Structural Biology

James Conway is currently serving as a Medicine Professor at University of Pittsburgh.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

James Conway

University of Pittsburgh

Professor

You can click a keyword to filter the displayed items

Video Presentations

Notable Scholarly Works

Notable Federal Grants

Collaborators

Myxococcus Xanthus Encapsulin Cargo Protein Encd is a Flavin-Binding Protein With Ferric Reductase Activity. Proceedings of the National Academy of Sciences (2024)

Elif ErenNorman R. WattsJames F. ConwayPaul T. Wingfield

gene expressionprotein functionprotein structureflavin-binding proteinmolecular biologyhost-guest chemistrystructural biologyprotein sciencemicrobiologyferric reductase activitycell biology

Inhibition of Irhom1 by Cd44-Targeting Nanocarrier for Improved Cancer Immunochemotherapy. Nature Communications (2024)

Zhangyi LuoYixian HuangNeelu BatraYuang ChenHaozhe HuangYifei WangZiqian ZhangShichen LiChien-Yu ChenZehua WangJingjing SunQiming Jane WangDa YangBinfeng LuJames F. ConwayLu-Yuan LiAi-Ming YuSong Li

Pneumococcal Extracellular Vesicles Mediate Horizontal Gene Transfer via the Transformation Machinery. mSphere (2024)

Sarah Werner LassBailey E. SmithShaw CamphireRory A. EutseyJojo A. PrenticeSaigopalakrishna S. YerneniAshni ArunAndrew A. BridgesJason W. RoschJames F. ConwayPhil CampbellN. Luisa Hiller

transformation machineryepidemiologymolecular and cellular biologyhorizontal gene transferpneumococcal extracellular vesiclesmolecular biologymicrobiology

Structural Basis of Deoxynucleotide Addition by Hiv-1 Rt During Reverse Transcription. Nature Communications (2024)

Sandra VergaraXiaohong ZhouUlises SantiagoMounia Alaoui-El-AzherJames F. ConwayNicolas Sluis-CremerGuillermo Calero

Structure of Biofilm-Forming Functional Amyloid Psmα1 From Staphylococcus Aureus. Proceedings of the National Academy of Sciences (2024)

Kasper Holst HansenChang Hyeock ByeonQian LiuTaner DraceThomas BoesenJames F. ConwayMaria AndreasenÜmit Akbey

biofilmsmicrobiology

A Structural Dendrogram of the Actinobacteriophage Major Capsid Proteins Provides Important Structural Insights Into the Evolution of Capsid Stability. Structure (2023)

Jennifer M. PodgorskiKrista FreemanSophia GosselinAlexis HuetJames F. ConwayMary BirdJohn GreccoShreya PatelDeborah Jacobs-SeraGraham HatfullJohann Peter GogartenJanne RavanttiSimon J. White

capsid stabilityprotein structurestructural dendrogramstructural biologymicrobiologyevolutionary biology

A Symmetry Mismatch Unraveled: How Phage Hk97 Scaffold Flexibly Accommodates a 12-Fold Pore at a 5-Fold Viral Capsid Vertex. Science Advances (2023)

Alexis HuetBonnie OhJosh MaurerRobert L. DudaJames F. Conway

Insights Into a Viral Motor: The Structure of the Hk97 Packaging Termination Assembly. Nucleic Acids Research (2023)

Dorothy E D P HawkinsOliver W BayfieldHerman K H FungDaniel N GrbaAlexis HuetJames F ConwayAlfred A Antson

viral motorvirologymolecular biologysequence assemblystructural biology

Ionic Liquid-Coated Lipid Nanoparticles Increase Sirna Uptake Into Cns Targets. Nanoscale Advances (2023)

Purva KhareSara X. EdgecombChristine M. HamadaniJames F. ConwayEden E. L. TannerDevika S Manickam

nanobiotechnologymaterials sciencenanomedicinenanoscale sciencenanoscale chemistrycns targetsnanoparticle researchbiomolecular engineeringmolecular biologynanomaterialsnanotechnology

Structures of Kinetic Intermediate States of Hiv-1 Reverse Transcriptase Dna Synthesis. bioRxiv (Cold Spring Harbor Laboratory) (2023)

Sandra VergaraXiahong ZhouUlises SantiagoJames F ConwayNicolas Sluis-CremerGuillermo Calero

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