Faculty

Institution

Unit

Venue

Isaac Pessah

Associate Dean and Professor

University of California, Davis

Affiliations

School of Veterinary Medicine

Department of Molecular Biosciences

Isaac Pessah is currently serving as a Molecular Biosciences Associate Dean and Professor at University of California, Davis.

Honors

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Experiences

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Education

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Isaac Pessah

University of California, Davis

Associate Dean and Professor

You can click a keyword to filter the displayed items

neuroscience pharmacology molecular biology biochemistry membrane biology receptors signal transduction toxicology molecular physiology gene expression protein science autism cellular physiology skeletal muscle biological chemistry neurophysiology hyperthermia receptor (biochemistry) neuropharmacology mammalian biology medicinal research muscle function vascular biology neurochemistry ryanodine receptor receptor tyrosine kinases animal physiology redox biology liver physiology molecular neurobiology ryanodine receptors neurodevelopmental disorders neurotransmission cardiac muscle autism spectrum disorders biomolecular structure psychiatric genetics biomolecular interactions malignant hyperthermia peptides cardiovascular research brain-immune interaction inhibitory activity cellular neurobiology developmental exposure skeletal myotubes molecular metabolism toxins developmental genetics functional modification experimental toxicology cell physiology sarcoplasmic reticulum environmental exposures release mechanism neural science protein function toxicological mechanism redox signaling cardiovascular pharmacology ryanodine receptor complex structure-activity relationship neuropeptide receptors neurotransmitters muscle injury integrative biology biomedical research key site conformational studies conformational coupling excitation-coupled calcium entry phenotypic context aryl hydrocarbon receptor polychlorinated biphenyls case-control study ryanodine receptor-dependent mechanisms physiology in vitro toxicology developmental neurotoxicity environmental toxicology developmental biology neuroprotection toxicological aspect marine drug developmental toxicology

Notable Scholarly Works

Notable Federal Grants

Collaborators

Deleterious Coding Variation Associated With Autism is Consistent Across Populations, as Exemplified by Admixed Latin American Populations. (2025)

Marina Natividad AvilaSeulgi JungF. Kyle SatterstromJack M. FuTess LevyLaura G. SloofmanLambertus KleiThariana PichardoChristine R. StevensCaroline M. CusickJennifer L. AmesGabriele S. CamposHilda CerrosRoberto ChaskelClaudia I. S. CostaMichael L. CuccaroAndrea del Pilar LopezMagdalena FernandezEugenio FerroLiliana GaleanoAna Cristina D. E. S. GirardiAnthony J. GriswoldLuis C. HernandezNaila LourençoYunin LudenaDiana L. NuñezRosa OyamaKatherine P. PeñaIsaac PessahRebecca SchmidtHolly M. SweeneyLizbeth TolentinoJaqueline Y. T. WangLilia Albores-GalloLisa A. CroenCarlos S. Cruz-FuentesIrva Hertz-PicciottoAlexander KolevzonMaria C. LattigLiliana MayoMaria Rita Passos-BuenoMargaret A. Pericak-VancePaige M. SiperFlora TassoneM. Pilar TrellesMichael E. TalkowskiMark J. DalyBehrang MahjaniSilvia De RubeisEdwin H. CookKathryn RoederCatalina BetancurBernie DevlinJoseph D. Buxbaum

human variationautismpopulation geneticsneurodiversitybehavioral sciencesneurodevelopmental disorderspublic healthpsychologydevelopmental psychopathologygenetic variation

The Piezo Channel is a Mechano-Sensitive Complex Component in the Mammalian Inner Ear Hair Cell. Nature Communications (2024)

Jeong Han LeeMaria C. Perez-FloresSeojin ParkHyo Jeong KimYingying ChenMincheol KangJennifer KersigoJinsil ChoiPhung N. ThaiRyan L. WoltzDolores Columba Perez-FloresGuy PerkinsChoong-Ryoul SihnPauline TrinhXiao-Dong ZhangPadmini SirishYao DongWayne Wei FengIsaac N. PessahRose E. DixonBernd SokolowskiBernd FritzschNipavan ChiamvimonvatEbenezer N. Yamoah

biophysicscell biomechanicssystems neurosciencepiezo channelelectrophysiologyneurosciencemembrane biologyphysiologymammalian biologyneurophysiologyhearing researchmechano-sensitive complex component

The α4 Nicotinic Acetylcholine Receptor is Necessary for the Initiation of Organophosphate-Induced Neuronal Hyperexcitability. Toxics (2024)

Peter M. AndrewWei FengJonas J. CalsbeekShane P. AntrobusGennady A. CherednychenkoJeremy A. MacMahonPedro N. BernardinoXiuzhen LiuDanielle J. HarveyPamela J. LeinIsaac N. Pessah

receptorsneuropharmacologycell signalingneurosciencepharmacologyregulatory toxicologyneurologytoxicology

Ex Vivo Exposure to Polybrominated Diphenyl Ether (Pbde) Selectively Affects the Immune Response in Autistic Children. Brain Behavior & Immunity - Health (2023)

Marjannie Eloi AkintundeYan-ping LinPaula KrakowiakIsaac N. PessahIrva Hertz-PicciottoBirgit PuschnerPaul AshwoodJudy Van de Water

psychiatryimmune responsesautismex vivo exposureneurosciencebrain-immune interactionneuroimmunologyimmunologyautistic children

Investigations Into Hydrogen Sulfide-Induced Suppression of Neuronal Activity in Vivo and Calcium Dysregulation in Vitro. Toxicological Sciences (2023)

Dong-Suk KimIsaac N PessahCristina M SantanaBenton S PurnellRui LiGordon F BuchananWilson K Rumbeiha

in vitro toxicologyhydrogen sulfide-induced suppressionneurosciencepharmacologyneurologytoxicology

Putative Malignant Hyperthermia Mutation Cav1.1-R174W is Insufficient to Trigger a Fulminant Response to Halothane or Confer Heat Stress Intolerance. Journal of Biological Chemistry (2023)

Wei FengJose R. LopezShane AntrobusJing ZhengArkady UryashYao DongDonald BeqollariRoger A. BannisterPhilip M. HopkinsKurt G. BeamPaul D. AllenIsaac.N. Pessah

medicinebiological chemistrypharmacologyhyperthermiamolecular biologymolecular medicine

The Piezo Channel is Central to the Mechano-Sensitive Channel Complex in the Mammalian Inner Ear.. Research Square (Research Square) (2023)

Jeong-Han LeeCristina Perez-FloresSeojin ParkHyo J KimYingying ChenMincheol KangJennifer KersigoJinsil ChoiPhung ThaiRyan WoltzGuy PerkinsChoong-Ryoul SihnBernd FritzschPauline TrinhXiao-Dong ZhangNipavan ChiamvimonvatDolores Perez-FloresPadmini SirishYao DongIsaac PessahFeng WeiRose DixonBernd SokolowskiEbenezer Yamoah

biophysicssystems neurosciencepiezo channelmechano-sensitive channel complexelectrophysiologyneurosciencemammalian inner earphysiologymammalian biologyneurophysiology

Dehydropiandrosterone (Dhea) Reduces Core Body Temperature and Protects Against Heat Stress Intolerance in Ryr1-T4826Ihsi Malignant Hyperthermia Susceptible Mice. Biophysical Journal (2022)

Shane AntrobusWei FengIsaac N. Pessah

biophysicstumor biologyheat stress intoleranceresidual stresscore body temperaturebiophysical aspectmolecular physiologyoxidative stressbiophysical modelingbiophysical reviewphysiologyhyperthermiamolecular medicinemolecular biologyexperimental biophysicsstress (biology)biomarkers

Rare Coding Variation Provides Insight Into the Genetic Architecture and Phenotypic Context of Autism. Nature Genetics (2022)

Jack M. FuF. Kyle SatterstromMinshi PengHarrison BrandRyan L. CollinsShan DongBrie WamsleyLambertus KleiLily WangStephanie P. HaoChristine R. StevensCaroline CusickMehrtash BabadiEric BanksBrett CollinsSheila DodgeStacey B. GabrielLaura GauthierSamuel K. LeeLindsay LiangAlicia LjungdahlBehrang MahjaniLaura SloofmanAndrey N. SmirnovMafalda BarbosaCatalina BetancurAlfredo BruscoBrian H. Y. ChungEdwin H. CookMichael L. CuccaroEnrico DomeniciGiovanni Battista FerreroJ. Jay GargusGail E. HermanIrva Hertz-PicciottoPatricia MacielDara S. ManoachMaria Rita Passos-BuenoAntonio M. PersicoAlessandra RenieriJames S. SutcliffeFlora TassoneElisabetta TrabettiGabriele CamposSimona CardaropoliDiana CarliMarcus C. Y. ChanChiara FalleriniElisa GiorgioAna Cristina GirardiEmily Hansen-KissSo Lun LeeCarla LintasYunin LudenaRachel NguyenLisa PavinatoMargaret Pericak-VanceIsaac N. PessahRebecca J. SchmidtMoyra SmithClaudia I. S. CostaSlavica TrajkovaJaqueline Y. T. WangMullin H. C. YuBranko AleksicMykyta ArtomovElisa BenettiMonica Biscaldi-SchaferAnders D. BørglumAngel CarracedoAndreas G. ChiocchettiHilary CoonRyan N. DoanMontserrat Fernández-PrietoChristine M. FreitagSherif GergesStephen GuterDavid M. HougaardChristina M. HultmanSuma JacobMiia KaartinenAlexander KolevzonItaru KushimaTerho LehtimäkiCaterina Lo RizzoNell MaltmanMarianna ManaraGal MeiriIdan MenasheJudith MillerNancy MinshewMatthew MosconiNorio OzakiAarno PalotieMara ParelladaKaija PuuraAbraham ReichenbergSven SandinStephen W. SchererSabine Schlitt

geneticsautismpsychiatric geneticsgenetic architecturephenotypic contextgenomicshuman genetics

Ryanodine Receptor-Active Non-Dioxin-Like Polychlorinated Biphenyls Cause Neurobehavioral Deficits in Larval Zebrafish. Frontiers in Toxicology (2022)

Bianca YaghoobiGalen W. MillerErika B. HollandXueshu LiDanielle HarveyShuyang LiHans-Joachim LehmlerIsaac N. PessahPamela J. Lein

larval zebrafishanimal behaviorneurosciencefish biologypharmacologyneurologytoxicology

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Isaac Pessah

Associate Dean and Professor

University of California, Davis

Affiliations

School of Veterinary Medicine

Department of Molecular Biosciences

Isaac Pessah is currently serving as a Molecular Biosciences Associate Dean and Professor at University of California, Davis.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Isaac Pessah

University of California, Davis

Associate Dean and Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Deleterious Coding Variation Associated With Autism is Consistent Across Populations, as Exemplified by Admixed Latin American Populations. (2025)

human variationautismpopulation geneticsneurodiversitybehavioral sciencesneurodevelopmental disorderspublic healthpsychologydevelopmental psychopathologygenetic variation

The Piezo Channel is a Mechano-Sensitive Complex Component in the Mammalian Inner Ear Hair Cell. Nature Communications (2024)

biophysicscell biomechanicssystems neurosciencepiezo channelelectrophysiologyneurosciencemembrane biologyphysiologymammalian biologyneurophysiologyhearing researchmechano-sensitive complex component

The α4 Nicotinic Acetylcholine Receptor is Necessary for the Initiation of Organophosphate-Induced Neuronal Hyperexcitability. Toxics (2024)

Peter M. AndrewWei FengJonas J. CalsbeekShane P. AntrobusGennady A. CherednychenkoJeremy A. MacMahonPedro N. BernardinoXiuzhen LiuDanielle J. HarveyPamela J. LeinIsaac N. Pessah

receptorsneuropharmacologycell signalingneurosciencepharmacologyregulatory toxicologyneurologytoxicology

Ex Vivo Exposure to Polybrominated Diphenyl Ether (Pbde) Selectively Affects the Immune Response in Autistic Children. Brain Behavior & Immunity - Health (2023)

Marjannie Eloi AkintundeYan-ping LinPaula KrakowiakIsaac N. PessahIrva Hertz-PicciottoBirgit PuschnerPaul AshwoodJudy Van de Water

psychiatryimmune responsesautismex vivo exposureneurosciencebrain-immune interactionneuroimmunologyimmunologyautistic children

Investigations Into Hydrogen Sulfide-Induced Suppression of Neuronal Activity in Vivo and Calcium Dysregulation in Vitro. Toxicological Sciences (2023)

Dong-Suk KimIsaac N PessahCristina M SantanaBenton S PurnellRui LiGordon F BuchananWilson K Rumbeiha

in vitro toxicologyhydrogen sulfide-induced suppressionneurosciencepharmacologyneurologytoxicology

Putative Malignant Hyperthermia Mutation Cav1.1-R174W is Insufficient to Trigger a Fulminant Response to Halothane or Confer Heat Stress Intolerance. Journal of Biological Chemistry (2023)

Wei FengJose R. LopezShane AntrobusJing ZhengArkady UryashYao DongDonald BeqollariRoger A. BannisterPhilip M. HopkinsKurt G. BeamPaul D. AllenIsaac.N. Pessah

medicinebiological chemistrypharmacologyhyperthermiamolecular biologymolecular medicine

The Piezo Channel is Central to the Mechano-Sensitive Channel Complex in the Mammalian Inner Ear.. Research Square (Research Square) (2023)

biophysicssystems neurosciencepiezo channelmechano-sensitive channel complexelectrophysiologyneurosciencemammalian inner earphysiologymammalian biologyneurophysiology

Dehydropiandrosterone (Dhea) Reduces Core Body Temperature and Protects Against Heat Stress Intolerance in Ryr1-T4826Ihsi Malignant Hyperthermia Susceptible Mice. Biophysical Journal (2022)

Shane AntrobusWei FengIsaac N. Pessah

Rare Coding Variation Provides Insight Into the Genetic Architecture and Phenotypic Context of Autism. Nature Genetics (2022)

geneticsautismpsychiatric geneticsgenetic architecturephenotypic contextgenomicshuman genetics

Ryanodine Receptor-Active Non-Dioxin-Like Polychlorinated Biphenyls Cause Neurobehavioral Deficits in Larval Zebrafish. Frontiers in Toxicology (2022)

Bianca YaghoobiGalen W. MillerErika B. HollandXueshu LiDanielle HarveyShuyang LiHans-Joachim LehmlerIsaac N. PessahPamela J. Lein

larval zebrafishanimal behaviorneurosciencefish biologypharmacologyneurologytoxicology

1
2
3
4
5
31
10 / page

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membrane transport

electrophysiology

Heidi E. Hamm, Ph.D.

Institution

Vanderbilt University

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photoreceptor cell

Palmer Taylor

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chemistry

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cardiovascular translational research

Alfred George

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cellular physiology

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hypertension

Craig W. Lindsley, Ph.D

Institution

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neuroscience

medicine

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Institution

University of Louisville

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