Faculty

Institution

Unit

Venue

Charles Iden

Professor Emeritus

Stony Brook University

Affiliations

Renaissance School of Medicine

Pharmacological Sciences

Charles Iden is currently serving as a Pharmacological Sciences Professor Emeritus at Stony Brook University.

Honors

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Experiences

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Education

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Charles Iden

Stony Brook University

Professor Emeritus

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molecular biology chemistry biochemistry toxicology analytical chemistry genetics organic synthesis chemical synthesis mass spectrometry biological chemistry oligomeric dna structural biology organic chemistry chemical biology cancer biology clinical chemistry chemical sciences nucleic acids redox biology nucleic acid chemistry natural product synthesis dna analysis protein science genome biology molecular metabolism enzyme inhibition vascular biology protein chemistry environmental analytical chemistry dna nanotechnology sequence analysis biomolecular analysis cancer genetics functional modification aquatic environment total synthesis aristolochic acids aristolactam-dna adducts structural molecular biology biochemical sciences circulatory physiology sustainable chemistry mammalian biology bioenergetics environmental pollution pollution assessment chemical pollution estuaries environmental fate molecular catalysis biocatalysis enzyme catalysis glycosylation chemical analysis environmental analysis human biomonitoring cancer risk heterocyclic oligonucleotides leaching radioactive waste disposal nuclear engineering derivative (chemistry) experimental toxicology nutrient physiology deoxyribose cleavage bleomycin-induced strand-scission alkylphenol ethoxylate metabolites sewage influent steroid conjugates immunoaffinity extraction steroid estrogens nonylphenol ethoxylates environmental samples vascular endothelial cells site-specific mutagenesis studies toxicological mechanism dna repair

Notable Scholarly Works

Notable Federal Grants

Collaborators

Structural and Mechanistic Insights Into the Transport of Aristolochic Acids and Their Active Metabolites by Human Serum Albumin. Journal of Biological Chemistry (2024)

Sergei PomyalovConceição A MinettiDavid P RemetaRadha BonalaFrancis JohnsonIrina ZaitsevaCharles IdenUrszula GolebiewskaKenneth J BreslauerGil ShohamViktoriya S SidorenkoArthur P Grollman

active metabolitesdrug metabolismprotein structurefunctional selectivitymechanistic insightsbiological chemistrybiochemistryprotein transportchemical biologyenzymesprotein sciencemembrane biologysecondary metabolitesprotein chemistryenzyme inhibitionhuman serum albuminbiomolecular engineeringmolecular biologyaristolochic acids

Abstract 4660: Molecular Mechanisms by Which a Bioactivated Human Carcinogen is Transported to Target Tissues. Cancer Research (2019)

Sergei PomyalovRadha BonalaRobert RiegerIrina ZaitsevaCharles IdenJohn HaleyRobert TureskyFrancis JohnsonThomas RosenquistArthur P. GrollmanGil ShohamViktoriya S. Sidorenko

pharmacologyradiation oncologycancer researchurologyoncologymolecular mechanismscancer biologytumor biology

Abstract 5241: Using Affinity Probes to Explore the Nephrotoxicity of Aristolochic Acid. Cancer Research (2017)

Viktoriya S. SidorenkoKathleen G. DickmanThomas RosenquistRadha BonalaSivaprasad AttaluriIrina ZaitsevaCharles IdenFrancis JohnsonArthur P. Grollman

pharmacologyaristolochic acidcancer researchurologyoncologycancer treatmentcancer biologyhealth sciencesaffinity probes

Sulfotransferase-1A1-Dependent Bioactivation of Aristolochic Acid I and N -Hydroxyaristolactam I in Human Cells. Carcinogenesis (2016)

Keiji HashimotoIrina N. ZaitsevaRadha BonalaSivaprasad AttaluriKatherine OzgaCharles R. IdenFrancis JohnsonMasaaki MoriyaArthur P. GrollmanViktoriya S. Sidorenko

carcinogenesisenzyme inhibitionpharmacologycancer geneticscancer researchurologycancer growthenzymescancer biologytumor biologycell biology

Impact of Thymine Glycol Damage on Dna Duplex Energetics: Correlations With Lesion‐Induced Biochemical and Structural Consequences. Biopolymers (2015)

Conceição A. S. A. MinettiDavid P. RemetaCharles R. IdenFrancis JohnsonArthur P. GrollmanKenneth J. Breslauer

biophysicsstructural consequencesthymine glycol damagekey sitegeneticsmolecular biologydna repairstructural biologybioenergeticsbiopolymers

Bioactivation of the Human Carcinogen Aristolochic Acid. Carcinogenesis (2014)

Viktoriya S. SidorenkoSivaprasad AttaluriIrina ZaitsevaCharles R. IdenKathleen G. DickmanFrancis JohnsonArthur P. Grollman

carcinogenesiscancer researchmolecular biologycancer riskcancer biologypathologybiochemistry

Total Synthesis of the Aristolochic Acids, Their Major Metabolites, and Related Compounds. Chemical Research in Toxicology (2014)

Sivaprasad AttaluriCharles R. IdenRadha R. BonalaFrancis Johnson

total synthesisrelated compoundsaristolochic acidstoxicologychemistrymajor metabolites

Biomonitoring of Aristolactam-Dna Adducts in Human Tissues Using Ultra-Performance Liquid Chromatography/Ion-Trap Mass Spectrometry. Chemical Research in Toxicology (2012)

Byeong Hwa YunThomas A. RosenquistViktoriya SidorenkoCharles R. IdenChung-Hsin ChenYeong-Shiau PuRadha BonalaFrancis JohnsonKathleen G. DickmanArthur P. GrollmanRobert J. Turesky

pharmacologyhuman biomonitoringanalytical chemistryaristolactam-dna adductsmolecular biologytoxicologymass spectrometrybiochemistry

Metabolic Activation of Aristolochic Acid and Mechanism of Repair of Aristolactam-Dna Adducts in Human Cells. (2012)

Viktoriya SidorenkoSivaprasad AttaluriIrina N. ZaitsevaYoshimitsu OdaYoshiharu OkunoCharles IdenArthur P. GrollmanFrancis Johnson

neurologydermatologygene expressionmetabolic activationaristolochic acidvascular biologyaristolactam-dna adductsdna repairmetabolismfunctional modificationtumor biologymembrane biologycell biology

Aristolochic Acid I Metabolism in the Isolated Perfused Rat Kidney. Chemical Research in Toxicology (2011)

Horacio A. PriestapM. Cecilia TorresRobert A. RiegerKathleen G. DickmanTomoko FreshwaterDavid R. TaftManuel A. BarbieriCharles R. Iden

physiologyexperimental toxicologypharmacologynutrient physiologyregenerative medicinerenal functionnephrologyurologychemical biologytoxicologymetabolism

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Charles Iden

Professor Emeritus

Stony Brook University

Affiliations

Renaissance School of Medicine

Pharmacological Sciences

Charles Iden is currently serving as a Pharmacological Sciences Professor Emeritus at Stony Brook University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Charles Iden

Stony Brook University

Professor Emeritus

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Structural and Mechanistic Insights Into the Transport of Aristolochic Acids and Their Active Metabolites by Human Serum Albumin. Journal of Biological Chemistry (2024)

Sergei PomyalovConceição A MinettiDavid P RemetaRadha BonalaFrancis JohnsonIrina ZaitsevaCharles IdenUrszula GolebiewskaKenneth J BreslauerGil ShohamViktoriya S SidorenkoArthur P Grollman

Abstract 4660: Molecular Mechanisms by Which a Bioactivated Human Carcinogen is Transported to Target Tissues. Cancer Research (2019)

Sergei PomyalovRadha BonalaRobert RiegerIrina ZaitsevaCharles IdenJohn HaleyRobert TureskyFrancis JohnsonThomas RosenquistArthur P. GrollmanGil ShohamViktoriya S. Sidorenko

pharmacologyradiation oncologycancer researchurologyoncologymolecular mechanismscancer biologytumor biology

Abstract 5241: Using Affinity Probes to Explore the Nephrotoxicity of Aristolochic Acid. Cancer Research (2017)

Viktoriya S. SidorenkoKathleen G. DickmanThomas RosenquistRadha BonalaSivaprasad AttaluriIrina ZaitsevaCharles IdenFrancis JohnsonArthur P. Grollman

pharmacologyaristolochic acidcancer researchurologyoncologycancer treatmentcancer biologyhealth sciencesaffinity probes

Sulfotransferase-1A1-Dependent Bioactivation of Aristolochic Acid I and N -Hydroxyaristolactam I in Human Cells. Carcinogenesis (2016)

Keiji HashimotoIrina N. ZaitsevaRadha BonalaSivaprasad AttaluriKatherine OzgaCharles R. IdenFrancis JohnsonMasaaki MoriyaArthur P. GrollmanViktoriya S. Sidorenko

carcinogenesisenzyme inhibitionpharmacologycancer geneticscancer researchurologycancer growthenzymescancer biologytumor biologycell biology

Impact of Thymine Glycol Damage on Dna Duplex Energetics: Correlations With Lesion‐Induced Biochemical and Structural Consequences. Biopolymers (2015)

Conceição A. S. A. MinettiDavid P. RemetaCharles R. IdenFrancis JohnsonArthur P. GrollmanKenneth J. Breslauer

biophysicsstructural consequencesthymine glycol damagekey sitegeneticsmolecular biologydna repairstructural biologybioenergeticsbiopolymers

Bioactivation of the Human Carcinogen Aristolochic Acid. Carcinogenesis (2014)

Viktoriya S. SidorenkoSivaprasad AttaluriIrina ZaitsevaCharles R. IdenKathleen G. DickmanFrancis JohnsonArthur P. Grollman

carcinogenesiscancer researchmolecular biologycancer riskcancer biologypathologybiochemistry

Total Synthesis of the Aristolochic Acids, Their Major Metabolites, and Related Compounds. Chemical Research in Toxicology (2014)

Sivaprasad AttaluriCharles R. IdenRadha R. BonalaFrancis Johnson

total synthesisrelated compoundsaristolochic acidstoxicologychemistrymajor metabolites

Biomonitoring of Aristolactam-Dna Adducts in Human Tissues Using Ultra-Performance Liquid Chromatography/Ion-Trap Mass Spectrometry. Chemical Research in Toxicology (2012)

Byeong Hwa YunThomas A. RosenquistViktoriya SidorenkoCharles R. IdenChung-Hsin ChenYeong-Shiau PuRadha BonalaFrancis JohnsonKathleen G. DickmanArthur P. GrollmanRobert J. Turesky

pharmacologyhuman biomonitoringanalytical chemistryaristolactam-dna adductsmolecular biologytoxicologymass spectrometrybiochemistry

Metabolic Activation of Aristolochic Acid and Mechanism of Repair of Aristolactam-Dna Adducts in Human Cells. (2012)

Viktoriya SidorenkoSivaprasad AttaluriIrina N. ZaitsevaYoshimitsu OdaYoshiharu OkunoCharles IdenArthur P. GrollmanFrancis Johnson

neurologydermatologygene expressionmetabolic activationaristolochic acidvascular biologyaristolactam-dna adductsdna repairmetabolismfunctional modificationtumor biologymembrane biologycell biology

Aristolochic Acid I Metabolism in the Isolated Perfused Rat Kidney. Chemical Research in Toxicology (2011)

Horacio A. PriestapM. Cecilia TorresRobert A. RiegerKathleen G. DickmanTomoko FreshwaterDavid R. TaftManuel A. BarbieriCharles R. Iden

physiologyexperimental toxicologypharmacologynutrient physiologyregenerative medicinerenal functionnephrologyurologychemical biologytoxicologymetabolism

1
2
3
4
5
10 / page

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protein science

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