Faculty

Institution

Unit

Venue

Haizhen Zhong

Professor

University of Nebraska at Omaha

Affiliations

College of Arts and Sciences

Chemistry

Haizhen Zhong is currently serving as a Chemistry Professor at University of Nebraska At Omaha.

Honors

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Experiences

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Education

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Haizhen Zhong

University of Nebraska at Omaha

Professor

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pharmacology medicinal chemistry drug discovery medicine medicinal research enzyme inhibition rational drug design biochemistry molecular biology drug targeting pharmacotherapy protein science oncology pharmaceutical chemistry drug development anti-cancer agents cancer treatment drug targets biological evaluation cancer research pharmaceutical sciences molecular docking enzymes drug delivery computational chemistry organic synthesis clinical chemistry tumor targeting cancer care signaling pathways protein chemistry protein modeling pharmaceutical research cellular therapy pharmaceutics molecular cancer novel therapies selectivity studies virus research controlled release material chemistry vascular biology antiviral drug development cancer biology inhibitory activity cataracts pancreatic cancer x-ray crystallography angiogenesis small molecule inhibitors isoform-specific inhibition updated review free energy calculations matrix metalloproteinase inhibitors chemical sciences cellular biochemistry general virology oxysterol molecular virology virus structure viral structural protein gene regulation release mechanism polymer synthesis derivative (chemistry) experimental synthesis organic electronics ensemble-based receptor models inactive states protein tyrosine kinases computational studies peptidomimetic design antiangiogenesis drug design multiple pathways tumor vasculature mtor-selective inhibitors organic chemistry protein inhibitors drug metabolism nanoparticles

Notable Scholarly Works

Notable Federal Grants

Collaborators

Cannabidiol Promotes Intestinal Cholesterol Uptake Mediated by Pregnane X Receptor. Frontiers in Endocrinology (2024)

Conner BrownWangeci KariukiHaizhen A ZhongAudra KippesYipeng Sui

physiologyliver physiologypharmacologyintestinal cholesterol uptakehematologyendocrine researchsecondary metabolismendocrinologyhepatologycomparative endocrinologyhealth sciences

Selectivity Studies and Free Energy Calculations of Akt Inhibitors. Molecules (2024)

Haizhen A. ZhongDavid T. Goodwin

medicinal chemistryselectivity studiescomputational chemistrypharmacologyakt inhibitorsfree energy calculations

Targeting the Egfr/Ras/Raf Signaling Pathway in Anticancer Research: A Recent Update on Inhibitor Design and Clinical Trials (2020–2023). Expert Opinion on Therapeutic Patents (2024)

Rima HajjoDima A. SabbahSanaa K. BardaweelHaizhen A. Zhong

tumor targetingmedicineinhibitor designmolecular cancerpharmaceutical researchanticancer researchcancer researchdrug targetingcancer treatmentlung cancersignaling pathwaysreceptorsenzyme inhibitionpharmacologyradiation oncologypharmacotherapyoncologyclinical researchmedicinal researchcellular therapy

Binding and Selectivity Studies of Phosphatidylinositol 3-Kinase (Pi3K) Inhibitors. Journal of Molecular Graphics and Modelling (2023)

Mohammad Al HasanMatthew SabirianovGrace RedwineKaitlin GoettschStephen X. YangHaizhen A. Zhong

medicinal chemistryprotein chemistrypharmacologyselectivity studiesprotein modelingfunctional selectivitymolecular modellingmolecular pharmacologydrug discoverymolecular biologyprotein sciencebiochemistry

Curcumin Stereoisomer, Cis-Trans Curcumin, as a Novel Ligand to A1 and A3 Adenosine Receptors. Pharmaceuticals (2023)

Luke J. HamiltonMahesh PattabiramanHaizhen A. ZhongMichaela WalkerHilary VaughnSurabhi Chandra

medicinal chemistrymedicinereceptorspharmacologypharmaceutical chemistrycis-trans curcumincurcumin stereoisomerpharmaceutical researchadenosine receptorsdrug discoverynovel ligandpharmaceutical sciencesneuroscience

Docking and Selectivity Studies of Covalently Bound Janus Kinase 3 Inhibitors. International Journal of Molecular Sciences (2023)

Haizhen A. ZhongSuliman Almahmoud

immunologymedicinal chemistryreceptorsenzyme inhibitionpharmacologypharmaceutical chemistryprotein chemistryselectivity studiesmolecular sciencemolecular pharmacologyenzymesmolecular dockingdrug discoverymolecular biology

Targeting Brd4 and Pi3K Signaling Pathways for the Treatment of Medulloblastoma. Journal of Controlled Release (2023)

Bharti SethiVirender KumarThilina D JayasingheYuxiang DongDonald R RonningHaizhen A ZhongDonald W CoulterRam I Mahato

signaling pathwaysmedicinetumor targetingpharmacologycontrolled releasebiomedical engineeringcancer carecancer researchcell signalingcancer immunotherapycellular therapyanti-cancer agentsoncologymedicinal researchcancer treatmentcancer biologydrug delivery

A Novel Curcumin Isomer, Cis‐Trans Curcumin, Activates Adenosine Receptor Subtypes a 1 and a 3: Potential for Pain Therapy. The FASEB Journal (2022)

Luke J. HamiltonHilary VaughnMahesh PattabiramanHaizhen A. ZhongBrandon LuedtkeSurabhi Chandra

physiologymedicinal chemistryreceptorspain managementpharmacologyadenosine receptorpain therapycell signalingpain researchpharmacotherapysignal transductionneuroscience

Molecular Modeling of Allosteric Site of Isoform-Specific Inhibition of the Peroxisome Proliferator-Activated Receptor Pparγ. Biomolecules (2022)

Suliman AlmahmoudHaizhen A. Zhong

molecular modelingmolecular modellingallosteric sitebiomolecular engineeringmolecular biologystructural molecular biologyisoform-specific inhibitionstructural biologyprotein sciencemembrane biologymolecular physiologybiochemistry

An Updated Review on Betacoronavirus Viral Entry Inhibitors: Learning From Past Discoveries to Advance Covid-19 Drug Discovery. Current Topics in Medicinal Chemistry (2021)

Dima A. SabbahRima HajjoSanaa K. BardaweelHaizhen A. Zhong

medicinal chemistrymedicinepharmacologycovid-19pharmaceutical researchdrug discoveryupdated reviewpast discoveriesmedicinal researchpharmaceutical sciencesantiviral drug developmenttranslational medicine

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Haizhen Zhong

Professor

University of Nebraska at Omaha

Affiliations

College of Arts and Sciences

Chemistry

Haizhen Zhong is currently serving as a Chemistry Professor at University of Nebraska At Omaha.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Haizhen Zhong

University of Nebraska at Omaha

Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Cannabidiol Promotes Intestinal Cholesterol Uptake Mediated by Pregnane X Receptor. Frontiers in Endocrinology (2024)

Conner BrownWangeci KariukiHaizhen A ZhongAudra KippesYipeng Sui

physiologyliver physiologypharmacologyintestinal cholesterol uptakehematologyendocrine researchsecondary metabolismendocrinologyhepatologycomparative endocrinologyhealth sciences

Selectivity Studies and Free Energy Calculations of Akt Inhibitors. Molecules (2024)

Haizhen A. ZhongDavid T. Goodwin

medicinal chemistryselectivity studiescomputational chemistrypharmacologyakt inhibitorsfree energy calculations

Targeting the Egfr/Ras/Raf Signaling Pathway in Anticancer Research: A Recent Update on Inhibitor Design and Clinical Trials (2020–2023). Expert Opinion on Therapeutic Patents (2024)

Rima HajjoDima A. SabbahSanaa K. BardaweelHaizhen A. Zhong

Binding and Selectivity Studies of Phosphatidylinositol 3-Kinase (Pi3K) Inhibitors. Journal of Molecular Graphics and Modelling (2023)

Mohammad Al HasanMatthew SabirianovGrace RedwineKaitlin GoettschStephen X. YangHaizhen A. Zhong

Curcumin Stereoisomer, Cis-Trans Curcumin, as a Novel Ligand to A1 and A3 Adenosine Receptors. Pharmaceuticals (2023)

Luke J. HamiltonMahesh PattabiramanHaizhen A. ZhongMichaela WalkerHilary VaughnSurabhi Chandra

Docking and Selectivity Studies of Covalently Bound Janus Kinase 3 Inhibitors. International Journal of Molecular Sciences (2023)

Haizhen A. ZhongSuliman Almahmoud

Targeting Brd4 and Pi3K Signaling Pathways for the Treatment of Medulloblastoma. Journal of Controlled Release (2023)

Bharti SethiVirender KumarThilina D JayasingheYuxiang DongDonald R RonningHaizhen A ZhongDonald W CoulterRam I Mahato

A Novel Curcumin Isomer, Cis‐Trans Curcumin, Activates Adenosine Receptor Subtypes a 1 and a 3: Potential for Pain Therapy. The FASEB Journal (2022)

Luke J. HamiltonHilary VaughnMahesh PattabiramanHaizhen A. ZhongBrandon LuedtkeSurabhi Chandra

physiologymedicinal chemistryreceptorspain managementpharmacologyadenosine receptorpain therapycell signalingpain researchpharmacotherapysignal transductionneuroscience

Molecular Modeling of Allosteric Site of Isoform-Specific Inhibition of the Peroxisome Proliferator-Activated Receptor Pparγ. Biomolecules (2022)

Suliman AlmahmoudHaizhen A. Zhong

An Updated Review on Betacoronavirus Viral Entry Inhibitors: Learning From Past Discoveries to Advance Covid-19 Drug Discovery. Current Topics in Medicinal Chemistry (2021)

Dima A. SabbahRima HajjoSanaa K. BardaweelHaizhen A. Zhong

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degenerative disease

neurochemical biomarkers

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pathology

microbial infection

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future medicinal chemistry

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future medicinal chemistry

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protein-protein interactions

biomolecular engineering