Faculty

Institution

Unit

Venue

Frank Simmen

University of Arkansas for Medical Sciences

Affiliations

Department of Medicine and Physiology

NoneFrank Simmen is currently serving as a Medicine And Physiology faculty at University of Arkansas For Medical Sciences.

Honors

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Experiences

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Education

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Frank Simmen

University of Arkansas for Medical Sciences

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molecular biology endocrinology gene expression reproductive biology biology developmental biology genetics reproductive science reproductive physiology mammalian biology cancer research nutrition tumor biology reproductive endocrinology cancer biology animal reproduction female reproductive system membrane biology transcription factors reproductive health reproductive medicine human reproduction liver physiology cancer cells animal physiology endocrine research reproduction response biological chemistry oncogenes nutritional biochemistry embryonic development cancer prevention obstetrics and gynaecology protein science nutrient physiology soy protein isolate animal science molecular physiology molecular cell biology nutritional sciences transcription regulation protein expression human nutrition insulin signaling gene function endocrine-related cancers mammary gland insulin-like growth factor insulin-like growth factor-i endometrial epithelial cells developmental expression growth hormone alcohol abuse alcohol dependence medical nutrition integrative biology receptor (biochemistry) developmental endocrinology digestive tract comparative endocrinology appetite control plant reproduction preterm birth maternal complications metabolic regulation insulin-like growth factors igf binding proteins mouse model uterine endometrial cells dietary soy protein uterine endometrium early pregnancy epithelial phenotype neonatal growth autoimmune-prone mice human neuroblastoma

Notable Scholarly Works

Notable Federal Grants

Collaborators

KrüPpel-Like Factor-9 and KrüPpel-Like Factor-13: Highly Related, Multi-Functional, Transcriptional Repressors and Activators of Oncogenesis. Cancers (2023)

Frank A. SimmenIad AlhallakRosalia C. M. Simmen

molecular regulationoncogenic agentpathologystem cell researchmolecular cell biologycancer biologyreporter gene assaycancer researchtranscription (biology)tumor biologygene expressiontranscription regulationradiation oncologycancer discoverymolecular biologyoncologyoncogenescancer cellstranscriptional repressors

Malic Enzyme 1 (Me1) Promotes Adiposity and Hepatic Steatosis and Induces Circulating Insulin and Leptin in Obese Female Mice. International Journal of Molecular Sciences (2023)

Frank A. SimmenJohn Mark P. PabonaAhmed Al-DwairiIad AlhallakMaria Theresa E. MontalesRosalia C. M. Simmen

diabeteshepatic steatosismetabolismliver physiologybiochemistrymetabolic regulationendocrinologyvascular biologymolecular scienceobesityappetite controlinsulin signalingmetabolic syndromebiologymetabolic healthlipoprotein metabolismmolecular biologystructural molecular biologymetabolic pathwaysobese female mice

KrüPpel-Like Factor 9 (Klf9) Suppresses Hepatocellular Carcinoma (Hcc)-Promoting Oxidative Stress and Inflammation in Mice Fed High-Fat Diet. Cancers (2022)

Adam R. BrownIad AlhallakRosalia C. M. SimmenStepan B. MelnykMelissa E. Heard-LipsmeyerMaria Theresa E. MontalesDaniel HabenichtTrang T. VanFrank A. Simmen

disease progressionhigh-fat dietcancer researchcancer biologyhepatocellular carcinomaoxidative stressbiochemistryinflammation

Breast Adipose Regulation of Premenopausal Breast Epithelial Phenotype Involves Interleukin 10. Journal of Molecular Endocrinology (2021)

Iad AlhallakKeith G WolterAna Castro MunozFrank A SimmenRichard J WardStacy A PettyLin-Xi LiRosalia C M Simmen

breast adipose regulationendocrinologymolecular biologyepithelial phenotype

Lesion Genotype Modifies High-Fat Diet Effects on Endometriosis Development in Mice. Frontiers in Physiology (2021)

Melissa E. Heard-LipsmeyerIad AlhallakFrank A. SimmenStepan B. MelnykRosalia C. M. Simmen

physiologylesion genotypehigh-fat diet effectsendometriosis developmentmetabolism

Malic Enzyme 1 (Me1) in the Biology of Cancer: It is Not Just Intermediary Metabolism. Journal of Molecular Endocrinology (2020)

Frank A SimmenIad AlhallakRosalia C M Simmen

intermediary metabolismcancer researchbiologymolecular biologycancer biology

Metformin Promotes Anti-Tumor Biomarkers in Human Endometrial Cancer Cells. Reproductive Sciences (2020)

John Mark P PabonaAlexander F BurnettDustin M BrownCharles M QuickFrank A SimmenMaria Theresa E MontalesShi J LiuTyler RoseIad AlhallakEric R SiegelRosalia CM Simmen

metastasisbiomarker discoverygynecologic oncologygynecologyreproductive biologyanti-tumor biomarkersbiomarker (medicine)tumor microenvironmentcancer biologytumor suppressorsgynecologic cancerstumor biologybiomarker targetsystems biologyreproductive sciencemolecular biologyoncologyoncogenescancer cells

Sun-126 Distinct Molecular Phenotypes of Non-Diseased Breast Adipose Tissue of Pre-Menopausal Obese and Non-Obese Women May Underlie Differing Breast Cancer Risks. Journal of the Endocrine Society (2020)

Iad AlhallakKeith G WolterFrank A SimmenRichard Jon WardStacy A PettyRosalia C M Simmen

breast cancer risksendocrinologyobesitybreast cancermolecular biologynon-obese womencancer risk

Complex Epigenetic Patterns in Cerebellum Generated After Developmental Exposure to Trichloroethylene and/or High Fat Diet in Autoimmune-Prone Mice. Environmental Science Processes & Impacts (2019)

Sarah J. BlossomStepan B. MelnykFrank A. Simmen

immunologycomplex epigenetic patternsdevelopmental biologyenvironmental epigeneticsdevelopmental exposureenvironmental sciencemammalian biologyepigeneticsautoimmune-prone mice

Malic Enzyme 1 (Me1) is Pro-Oncogenic in Apcmin/+ Mice. Scientific Reports (2018)

Lorenzo M. FernandesAhmed Al-DwairiRosalia C. M. SimmenMeera MarjiDustin M. BrownSarah W. JewellFrank A. Simmen

carcinogenesisenzyme inhibitioncancer researchsystems biologycancer discoverymolecular biologyoncogenic agentoncogenescancer cellstumor biologycell biology

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Frank Simmen

University of Arkansas for Medical Sciences

Affiliations

Department of Medicine and Physiology

NoneFrank Simmen is currently serving as a Medicine And Physiology faculty at University of Arkansas For Medical Sciences.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Frank Simmen

University of Arkansas for Medical Sciences

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

KrüPpel-Like Factor-9 and KrüPpel-Like Factor-13: Highly Related, Multi-Functional, Transcriptional Repressors and Activators of Oncogenesis. Cancers (2023)

Frank A. SimmenIad AlhallakRosalia C. M. Simmen

Malic Enzyme 1 (Me1) Promotes Adiposity and Hepatic Steatosis and Induces Circulating Insulin and Leptin in Obese Female Mice. International Journal of Molecular Sciences (2023)

Frank A. SimmenJohn Mark P. PabonaAhmed Al-DwairiIad AlhallakMaria Theresa E. MontalesRosalia C. M. Simmen

KrüPpel-Like Factor 9 (Klf9) Suppresses Hepatocellular Carcinoma (Hcc)-Promoting Oxidative Stress and Inflammation in Mice Fed High-Fat Diet. Cancers (2022)

Adam R. BrownIad AlhallakRosalia C. M. SimmenStepan B. MelnykMelissa E. Heard-LipsmeyerMaria Theresa E. MontalesDaniel HabenichtTrang T. VanFrank A. Simmen

disease progressionhigh-fat dietcancer researchcancer biologyhepatocellular carcinomaoxidative stressbiochemistryinflammation

Breast Adipose Regulation of Premenopausal Breast Epithelial Phenotype Involves Interleukin 10. Journal of Molecular Endocrinology (2021)

Iad AlhallakKeith G WolterAna Castro MunozFrank A SimmenRichard J WardStacy A PettyLin-Xi LiRosalia C M Simmen

breast adipose regulationendocrinologymolecular biologyepithelial phenotype

Lesion Genotype Modifies High-Fat Diet Effects on Endometriosis Development in Mice. Frontiers in Physiology (2021)

Melissa E. Heard-LipsmeyerIad AlhallakFrank A. SimmenStepan B. MelnykRosalia C. M. Simmen

physiologylesion genotypehigh-fat diet effectsendometriosis developmentmetabolism

Malic Enzyme 1 (Me1) in the Biology of Cancer: It is Not Just Intermediary Metabolism. Journal of Molecular Endocrinology (2020)

Frank A SimmenIad AlhallakRosalia C M Simmen

intermediary metabolismcancer researchbiologymolecular biologycancer biology

Metformin Promotes Anti-Tumor Biomarkers in Human Endometrial Cancer Cells. Reproductive Sciences (2020)

John Mark P PabonaAlexander F BurnettDustin M BrownCharles M QuickFrank A SimmenMaria Theresa E MontalesShi J LiuTyler RoseIad AlhallakEric R SiegelRosalia CM Simmen

Iad AlhallakKeith G WolterFrank A SimmenRichard Jon WardStacy A PettyRosalia C M Simmen

breast cancer risksendocrinologyobesitybreast cancermolecular biologynon-obese womencancer risk

Complex Epigenetic Patterns in Cerebellum Generated After Developmental Exposure to Trichloroethylene and/or High Fat Diet in Autoimmune-Prone Mice. Environmental Science Processes & Impacts (2019)

Sarah J. BlossomStepan B. MelnykFrank A. Simmen

immunologycomplex epigenetic patternsdevelopmental biologyenvironmental epigeneticsdevelopmental exposureenvironmental sciencemammalian biologyepigeneticsautoimmune-prone mice

Malic Enzyme 1 (Me1) is Pro-Oncogenic in Apcmin/+ Mice. Scientific Reports (2018)

Lorenzo M. FernandesAhmed Al-DwairiRosalia C. M. SimmenMeera MarjiDustin M. BrownSarah W. JewellFrank A. Simmen

carcinogenesisenzyme inhibitioncancer researchsystems biologycancer discoverymolecular biologyoncogenic agentoncogenescancer cellstumor biologycell biology

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