Faculty

Institution

Unit

Venue

Erkang Fan

Research Associate Professor of Biochemistry

University of Washington

Affiliations

School of Medicine

Biochemistry

Erkang Fan is currently serving as a Biochemistry Research Associate Professor of Biochemistry at University of Washington.

Honors

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Experiences

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Education

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Erkang Fan

University of Washington

Research Associate Professor of Biochemistry

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pharmacology medicinal chemistry drug discovery medicine infectious diseases structural biology molecular biology enzyme inhibition enzymes organic chemistry clinical microbiology protein science structural molecular biology protein structure medicinal research parasitology crystallography pharmaceutical chemistry drug targeting biological chemistry clinical chemistry biomolecular structure antimicrobial agents antimicrobial chemotherapy pharmacotherapy applied microbiology rational drug design drug development crystal structures structural chemistry molecular structure molecular science cholera toxin receptor (biochemistry) rna biology antiparasitic agent x-ray crystallography selective inhibitors medical mycology protein x-ray crystallography protein chemistry emerging infectious diseases pharmaceutical sciences functional modification bumped kinase inhibitors genome biology clinical pharmacology antimicrobial susceptibility methionyl-trna synthetase heat-labile enterotoxin methionyl-trna synthetase inhibitors cryptosporidium parvum signal recognition biological inorganic chemistry toxinology drug targets infectious disease modelling antiviral drug development pharmacokinetics applied chemistry antiviral therapy molecular research protein synthesis protein biosynthesis biomolecular interactions molecular substrates structural genomics inhibitor design selective inhibition kinase inhibitors urea-based inhibitors solid-phase synthesis tryptophanyl-trna synthetase general mechanism wwe domains ation-dependent ubiquitination future medicinal chemistry pharmacognosy biochemistry neglected tropical diseases structure-based drug discovery pharmacological research mechanisms of action

Notable Scholarly Works

Notable Federal Grants

Collaborators

Structure Guided Modification of 2-Chloro-5-(Ethyl-Phenyl-Sulfamoyl)-N-[2-(2-Oxo-Pyrrolidin-1-Yl)-Phenyl]-Benzamide to Afford Selective Inhibitors of Cryptosporidium Parvum N-Myristoyltransferase. Bioorganic & Medicinal Chemistry Letters (2025)

Dilep K SigalapalliSophia GroustraMichael K FenwickRachael ZigweidMatthew A HulversonEric OwsleyMonique KhimSayaka ShibataWesley C Van VoorhisBart L StakerErkang Fan

therapeutic targetspharmaceutical chemistrychemical biologymolecular biologydrug discoveryinhibitory activitymedicinal researchmedicinal chemistrybiochemistrydrug resistancefunctional modificationfuture medicinal chemistryantimicrobial agentsremedial actionpeptide scienceselective inhibitorsspecific resistanceenzyme inhibitionbiomolecular engineering

A Novel Methionyl-Trna Synthetase Inhibitor Targeting Gram-Positive Bacterial Pathogens. Antimicrobial Agents and Chemotherapy (2024)

Nora M. R. MolaskyZhongsheng ZhangJ. Robert GillespieJohn DomagalaDawn ReynaElke LipkaErkang FanFrederick S. Buckner

antimicrobial agentsantimicrobial chemotherapyantimicrobial resistancemicrobiologygram-positive bacterial pathogens

Comparison of Physicochemical Parameters, Microbial Community Composition and Flavor Substances During Mechanical and Traditional Brewing Process of Jiang-Flavor Baijiu. Food Science and Biotechnology/Food science and biotechnology (2024)

Cheng WuJianfeng HuDan XieEndi FanJunlin YangXiaolong YouPingyan ChengWei HuangFeng HuDiqiang Wang

food technologyjiang-flavor baijiuphysicochemical parametersfood sciencefood processingflavor substancesmicrobiologytraditional brewing processfood microbiologymicrobial community compositionfood safetyfood biotechnology

Efficacy of the Bumped Kinase Inhibitor Bki-1708 Against the Cyst-Forming Apicomplexan Parasites Toxoplasma Gondii and Neospora Caninum in Vitro and in Experimentally Infected Mice. International Journal for Parasitology Drugs and Drug Resistance (2024)

Maria Cristina Ferreira de SousaDennis ImhofKai Pascal Alexander HänggeliRyan ChoiMatthew A. HulversonSamuel L.M. ArnoldWesley C. Van VoorhisErkang FanSánchez-Sánchez RobertoLuis M. Ortega-MoraAndrew Hemphill

neospora caninumparasitologyantiparasitic agentparasite controldrug resistancemedicinepharmacologymammalian biologycyst-forming apicomplexan parasites

Microbial Succession Law of the Daqu‐Making Environment in Jiang‐Flavor Daqu. Journal of food processing and preservation (2024)

Endi FanShangjie YaoXiaolong YouCheng WuJunlin YangYanshun YinJian ZhangPingyan ChengFeng HuJianfeng Hu

daqu-making environmentfood processingmicrobiologyfood microbiologyjiang-flavor daqumicrobial succession law

Molecular Targets of the 5-Amido-Carboxamide Bumped Kinase Inhibitor Bki-1748 in Cryptosporidium Parvum and Hct-8 Host Cells. International Journal of Molecular Sciences (2024)

Jubilee AjiboyeAnne-Christine UldryManfred HellerArunasalam NaguleswaranErkang FanWesley C. Van VoorhisAndrew HemphillJoachim Müller

drug targetingcell signalingimmunologymolecular medicinemolecular sciencemedicinal chemistrypharmacologymolecular biologymolecular pharmacologydrug discoveryenzyme inhibitioncryptosporidium parvummolecular targets

Comparison of Toxicities Among Different Bumped Kinase Inhibitor Analogs for Treatment of Cryptosporidiosis. Antimicrobial Agents and Chemotherapy (2023)

Matthew A. HulversonRyan ChoiDeborah A. SchaeferDana P. BetzerMolly C. McCloskeyGrant R. WhitmanWenlin HuangSangun LeeAndy PranataMalcolm D. McLeodKennan C. MarshDale J. KempfBruce E. LeRoyMark T. ZafiratosAimee L. BielinskiRobert C. HackmanKayode K. OjoSamuel L. M. ArnoldLynn K. BarrettSaul TziporiMichael W. RiggsErkang FanWesley C. Van Voorhis

clinical microbiologyepidemiologyantimicrobial agentsinfectious diseasesantimicrobial chemotherapyantimicrobial resistancepharmacologyinhibitor analogsveterinary medicineapplied microbiology

Identification of and Structural Insights Into Hit Compounds Targeting N -Myristoyltransferase for Cryptosporidium Drug Development. ACS Infectious Diseases (2023)

Michael K. FenwickAlexandra R. ReersYi LiuRachael ZigweidBanumathi SankaranJanis ShinMatthew A. HulversonBradley HammersonElena Fernández ÁlvaroPeter J. MylerAlexis KaushanskyWesley C. Van VoorhisErkang FanBart L. Staker

epidemiologydrug developmentinfectious diseasesstructural insightsdrug targetinglead identificationemerging infectious diseaseshit compoundspharmacologyhit identificationdrug discoveryenzyme inhibition

Repurposing the Kinase Inhibitor Mavelertinib for Giardiasis Therapy. Antimicrobial Agents and Chemotherapy (2022)

Samantha A. MichaelsMatthew A. HulversonGrant R. WhitmanLinh T. TranRyan ChoiErkang FanCase W. McNamaraMelissa S. LoveKayode K. Ojo

giardiasis therapyepidemiologykinase inhibitor mavelertinibantimicrobial chemotherapymedicinepharmacologyclinical researchpharmacotherapymedical mycology

Spontaneous Selection of Cryptosporidium Drug Resistance in a Calf Model of Infection. Antimicrobial Agents and Chemotherapy (2021)

Muhammad M. HasanErin E. StebbinsRobert K. M. ChoyJ. Robert GillespieEugenio L. de HostosPeter MillerAisha MushtaqRanae M. RanadeJosé E. TeixeiraChristophe L. M. J. VerlindeAdam SaterialeZhongsheng ZhangDamon M. OsbournDavid W. GriggsErkang FanFrederick S. BucknerChristopher D. Huston

spontaneous selectionclinical microbiologyepidemiologyanimal virusinfectious diseasesvirologyparasitologyantimicrobial resistancedrug resistanceveterinary microbiologyemerging infectious diseasescalf modelpharmacologyveterinary medicineinfectious disease modelling

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Erkang Fan

Research Associate Professor of Biochemistry

University of Washington

Affiliations

School of Medicine

Biochemistry

Erkang Fan is currently serving as a Biochemistry Research Associate Professor of Biochemistry at University of Washington.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Erkang Fan

University of Washington

Research Associate Professor of Biochemistry

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Dilep K SigalapalliSophia GroustraMichael K FenwickRachael ZigweidMatthew A HulversonEric OwsleyMonique KhimSayaka ShibataWesley C Van VoorhisBart L StakerErkang Fan

A Novel Methionyl-Trna Synthetase Inhibitor Targeting Gram-Positive Bacterial Pathogens. Antimicrobial Agents and Chemotherapy (2024)

Nora M. R. MolaskyZhongsheng ZhangJ. Robert GillespieJohn DomagalaDawn ReynaElke LipkaErkang FanFrederick S. Buckner

antimicrobial agentsantimicrobial chemotherapyantimicrobial resistancemicrobiologygram-positive bacterial pathogens

Cheng WuJianfeng HuDan XieEndi FanJunlin YangXiaolong YouPingyan ChengWei HuangFeng HuDiqiang Wang

neospora caninumparasitologyantiparasitic agentparasite controldrug resistancemedicinepharmacologymammalian biologycyst-forming apicomplexan parasites

Microbial Succession Law of the Daqu‐Making Environment in Jiang‐Flavor Daqu. Journal of food processing and preservation (2024)

Endi FanShangjie YaoXiaolong YouCheng WuJunlin YangYanshun YinJian ZhangPingyan ChengFeng HuJianfeng Hu

daqu-making environmentfood processingmicrobiologyfood microbiologyjiang-flavor daqumicrobial succession law

Molecular Targets of the 5-Amido-Carboxamide Bumped Kinase Inhibitor Bki-1748 in Cryptosporidium Parvum and Hct-8 Host Cells. International Journal of Molecular Sciences (2024)

Jubilee AjiboyeAnne-Christine UldryManfred HellerArunasalam NaguleswaranErkang FanWesley C. Van VoorhisAndrew HemphillJoachim Müller

Comparison of Toxicities Among Different Bumped Kinase Inhibitor Analogs for Treatment of Cryptosporidiosis. Antimicrobial Agents and Chemotherapy (2023)

clinical microbiologyepidemiologyantimicrobial agentsinfectious diseasesantimicrobial chemotherapyantimicrobial resistancepharmacologyinhibitor analogsveterinary medicineapplied microbiology

Identification of and Structural Insights Into Hit Compounds Targeting N -Myristoyltransferase for Cryptosporidium Drug Development. ACS Infectious Diseases (2023)

Repurposing the Kinase Inhibitor Mavelertinib for Giardiasis Therapy. Antimicrobial Agents and Chemotherapy (2022)

Samantha A. MichaelsMatthew A. HulversonGrant R. WhitmanLinh T. TranRyan ChoiErkang FanCase W. McNamaraMelissa S. LoveKayode K. Ojo

giardiasis therapyepidemiologykinase inhibitor mavelertinibantimicrobial chemotherapymedicinepharmacologyclinical researchpharmacotherapymedical mycology

Spontaneous Selection of Cryptosporidium Drug Resistance in a Calf Model of Infection. Antimicrobial Agents and Chemotherapy (2021)

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