Faculty

Institution

Unit

Venue

Nels C. Elde

Professor of Human Genetics and Adjunct Professor Biological Sciences

University of Utah

Affiliations

College of Science

School of Biological Sciences

Spencer Fox Eccles School of Medicine

Human Genetics

Nels C. Elde is currently serving as a College Of Science Professor of Human Genetics and Adjunct Professor Biological Sciences at University of Utah.

Honors

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Experiences

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Education

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Nels C. Elde

University of Utah

Professor of Human Genetics and Adjunct Professor Biological Sciences

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evolutionary biology virology immunology molecular biology genetics viral evolution genomics molecular evolution rapid evolution genome biology host-microbe interactions structural biology general virology avian biology viral genetics evolutionary microbiology virus-host interactions gene expression human genetics virus research mammalian biology fish biology evolutionary genetics gene evolution immune responses conservation biology adaptation clinical microbiology genome studies cellular biology virus transmission rna biology viral pathogenesis structural homology screens glycan recognition receptors regulatory toxicology heredity molecular ecology nucleic acids evolutionary applications sociobiology evolutionary anthropology poultry science industrial applicability regulatory consideration genetically modified organisms human retrovirus genome structure genome analysis comparative genomics genetic foundation sociogenomics virus epidemiology microbial toxins toxinology specie specificity long-read sequencing non-coding rna gene function long non-coding rna emergent virus synthetic virology covid-19 pandemic regulatory activities regulatory elements regulatory evolution immune genes macronuclear genome sequence ciliate tetrahymena thermophila host antiviral defenses genomic accordions viral mimicry evolutionary model cgas-mediated stabilization pathogen mimicry evolutionary conundrum virus evolution biological data genome sequencing

Notable Scholarly Works

Notable Federal Grants

Collaborators

Distinct Routes to Thermotolerance in the Fungal Pathogen Cryptococcus Neoformans. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Mara J. W. SchwiesowNels C. EldeZoë A. Hilbert

public healthimmunologymedical mycologyepidemiologyclinical microbiologyapplied microbiologymicrobial ecologyfungal pathogens

Evolution of Stat2 Resistance to Flavivirus Ns5 Occurred Multiple Times Despite Genetic Constraints. Nature Communications (2024)

Ethan C. VeitMadihah S. SalimMariel J. JungR. Blake RichardsonIan N. BoysMeghan QuinlanErika A. BarrallEva BednarskiRachael E. HamiltonCaroline KikawaNels C. EldeAdolfo García-SastreMatthew J. Evans

occurred multiple timesgeneral virologygeneticsviral geneticsevolutionary geneticsgenetic constraintsvirologyviral evolutionmolecular biologymolecular evolutiongene evolutionevolutionary biology

Hidden Evolutionary Constraints Dictate the Retention of Coronavirus Accessory Genes. Current Biology (2024)

Stephen A GoldsteinTeagan M FeeleyKristina M BablerZoë A HilbertDiane M DownhourNiema MoshiriNels C Elde

hidden evolutionary constraintscoronavirus accessory genesgeneticsvirologyviral evolutionmolecular biologymolecular evolutiongene evolutionevolutionary biology

Microbe Transmission From Pet Shop to Lab-Reared Zebrafish Reveals a Pathogenic Birnavirus. PLoS Biology (2024)

Marlen C. RiceAndrew J. JanikNels C. EldeJames A. GagnonKeir M. Balla

immunologyfish biologypathogenic birnavirusplo biologymicrobe transmissionvirologyinfectious diseasespet shopveterinary microbiologymicrobiology

Recurrent Viral Capture of Cellular Phosphodiesterases That Antagonize Oas-Rnase L. Proceedings of the National Academy of Sciences (2024)

Stephen A. GoldsteinNels C. Elde

immunologyvirologycellular phosphodiesterasesrecurrent viral capture

Distinct Pathways of Adaptive Evolution in Cryptococcus Neoformans Reveal a Mutation in Adenylyl Cyclase With Trade-Offs for Pathogenicity. Current Biology (2023)

Zoë A. HilbertJoseph M. BednarekMara J.W. SchwiesowKrystal Y. ChungChristian T. MoreauJessica C.S. BrownNels C. Elde

microbial pathogenesisadaptationadenylyl cyclaseevolutionary microbiologymolecular biologyadaptive evolutioncryptococcus neoformansmicrobiologyevolutionary biology

Rapid Evolution of Glycan Recognition Receptors Reveals an Axis of Host–Microbe Arms Races Beyond Canonical Protein–Protein Interfaces. Genome Biology and Evolution (2023)

Zoë A HilbertPaige E HaffenerHannah J YoungMara J W SchwiesowEllen M LefflerNels C Elde

immunologygenomicsgenome biologyrapid evolutioncanonical protein-protein interfacesglycan recognition receptorsevolutionary microbiologymolecular biologymolecular evolutionhost-microbe armstheoretical biologyevolutionary biologyhost-microbe interactions

Structural Homology Screens Reveal Host-Derived Poxvirus Protein Families Impacting Inflammasome Activity. Cell Reports (2023)

Ian N. BoysAlex G. JohnsonMeghan R. QuinlanPhilip J. KranzuschNels C. Elde

immunologyinflammasome activityvirologystructural biologystructural homology screenscell biology

Structural Homology Screens Reveal Poxvirus-Encoded Proteins Impacting Inflammasome-Mediated Defenses. bioRxiv (Cold Spring Harbor Laboratory) (2023)

Ian N. BoysAlex G. JohnsonMeghan QuinlanPhilip J. KranzuschNels C. Elde

immunologyvirus-host interactionspoxvirus-encoded proteinsinflammasome-mediated defensesmolecular biologystructural biologystructural homology screens

Virology Under the Microscope—a Call for Rational Discourse. Journal of Virology (2023)

Felicia GoodrumAnice C. LowenSeema LakdawalaJames AlwineArturo CasadevallMichael J. ImperialeWalter AtwoodDaphne AvgoustiJoel BainesBruce BanfieldLawrence BanksSumita Bhaduri-McIntoshDeepta BhattacharyaDaniel Blanco-MeloDavid BloomAdrianus BoonSteeve BoulantCurtis BrandtAndrew BroadbentChristopher BrookeCraig CameronSamuel CamposPatrizia CaposioGary ChanAnna CliffeJohn CoffinKathleen CollinsBlossom DamaniaMatthew DaughertyKari DebbinkJames DeCaprioTerence DermodyJimmy DikeakosDaniel DiMaioRhoel DinglasanW. Paul DuprexRebecca DutchNels EldeMichael EmermanLynn EnquistBentley FaneAna Fernandez-SesmaMichelle FlennikenLori FrappierMatthew FriemanKlaus FruehMichaela GackMarta GagliaTom GallagherDenise GallowayAdolfo García-SastreAdam GeballeBritt GlaunsingerStephen GoffAlexander GreningerMeaghan HancockEva HarrisNicholas HeatonMark HeiseEkaterina HeldweinBrenda HogueStacy HornerEdward HutchinsonJoseph HyserWilliam JacksonRobert KalejtaJeremy KamilStephanie KarstFrank KirchhoffDavid KnipeTimothy KowalikMichael LagunoffLaimonis LaiminsRyan LangloisAdam LauringBenhur LeeDavid LeibShan-Lu LiuRichard LongneckerCarolina LopezMicah LuftigJennifer LundBalaji ManicassamyGrant McFaddenMichael McIntoshAndrew MehleW. Allen MillerIan MohrCary MoodyNathaniel MoormanAnne MosconaBryan MounceJoshua MungerKarl MüngerEain MurphyMojgan NaghaviJay NelsonChristopher NeufeldtJanko NikolichChristine O'Connor

immunologycommunicable diseasesvirus researchsars-cov-2emergent viruscovid-19medical virologysynthetic virologygeneral virologyhuman pathogenscovid-19 pandemicviral pathogenesisvirologypublic concerninfectious diseasesrational discourse

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Nels C. Elde

Professor of Human Genetics and Adjunct Professor Biological Sciences

University of Utah

Affiliations

College of Science

School of Biological Sciences

Spencer Fox Eccles School of Medicine

Human Genetics

Nels C. Elde is currently serving as a College Of Science Professor of Human Genetics and Adjunct Professor Biological Sciences at University of Utah.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Nels C. Elde

University of Utah

Professor of Human Genetics and Adjunct Professor Biological Sciences

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Distinct Routes to Thermotolerance in the Fungal Pathogen Cryptococcus Neoformans. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Mara J. W. SchwiesowNels C. EldeZoë A. Hilbert

public healthimmunologymedical mycologyepidemiologyclinical microbiologyapplied microbiologymicrobial ecologyfungal pathogens

Evolution of Stat2 Resistance to Flavivirus Ns5 Occurred Multiple Times Despite Genetic Constraints. Nature Communications (2024)

Ethan C. VeitMadihah S. SalimMariel J. JungR. Blake RichardsonIan N. BoysMeghan QuinlanErika A. BarrallEva BednarskiRachael E. HamiltonCaroline KikawaNels C. EldeAdolfo García-SastreMatthew J. Evans

occurred multiple timesgeneral virologygeneticsviral geneticsevolutionary geneticsgenetic constraintsvirologyviral evolutionmolecular biologymolecular evolutiongene evolutionevolutionary biology

Hidden Evolutionary Constraints Dictate the Retention of Coronavirus Accessory Genes. Current Biology (2024)

Stephen A GoldsteinTeagan M FeeleyKristina M BablerZoë A HilbertDiane M DownhourNiema MoshiriNels C Elde

hidden evolutionary constraintscoronavirus accessory genesgeneticsvirologyviral evolutionmolecular biologymolecular evolutiongene evolutionevolutionary biology

Microbe Transmission From Pet Shop to Lab-Reared Zebrafish Reveals a Pathogenic Birnavirus. PLoS Biology (2024)

Marlen C. RiceAndrew J. JanikNels C. EldeJames A. GagnonKeir M. Balla

immunologyfish biologypathogenic birnavirusplo biologymicrobe transmissionvirologyinfectious diseasespet shopveterinary microbiologymicrobiology

Recurrent Viral Capture of Cellular Phosphodiesterases That Antagonize Oas-Rnase L. Proceedings of the National Academy of Sciences (2024)

Stephen A. GoldsteinNels C. Elde

immunologyvirologycellular phosphodiesterasesrecurrent viral capture

Distinct Pathways of Adaptive Evolution in Cryptococcus Neoformans Reveal a Mutation in Adenylyl Cyclase With Trade-Offs for Pathogenicity. Current Biology (2023)

Zoë A. HilbertJoseph M. BednarekMara J.W. SchwiesowKrystal Y. ChungChristian T. MoreauJessica C.S. BrownNels C. Elde

microbial pathogenesisadaptationadenylyl cyclaseevolutionary microbiologymolecular biologyadaptive evolutioncryptococcus neoformansmicrobiologyevolutionary biology

Rapid Evolution of Glycan Recognition Receptors Reveals an Axis of Host–Microbe Arms Races Beyond Canonical Protein–Protein Interfaces. Genome Biology and Evolution (2023)

Zoë A HilbertPaige E HaffenerHannah J YoungMara J W SchwiesowEllen M LefflerNels C Elde

Structural Homology Screens Reveal Host-Derived Poxvirus Protein Families Impacting Inflammasome Activity. Cell Reports (2023)

Ian N. BoysAlex G. JohnsonMeghan R. QuinlanPhilip J. KranzuschNels C. Elde

immunologyinflammasome activityvirologystructural biologystructural homology screenscell biology

Structural Homology Screens Reveal Poxvirus-Encoded Proteins Impacting Inflammasome-Mediated Defenses. bioRxiv (Cold Spring Harbor Laboratory) (2023)

Ian N. BoysAlex G. JohnsonMeghan QuinlanPhilip J. KranzuschNels C. Elde

immunologyvirus-host interactionspoxvirus-encoded proteinsinflammasome-mediated defensesmolecular biologystructural biologystructural homology screens

Virology Under the Microscope—a Call for Rational Discourse. Journal of Virology (2023)

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University of Colorado Boulder

virology

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