Faculty

Institution

Unit

Venue

Douglas Pittman

Associate Professor

University of South Carolina

Affiliations

College of Pharmacy

Department of Drug Discovery and Biomedical Sciences (ddbs)

Douglas Pittman is currently serving as a College Of Pharmacy Associate Professor at University of South Carolina.

Honors

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Experiences

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Education

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Douglas Pittman

University of South Carolina

Associate Professor

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genetics molecular biology dna repair cell biology pharmacology cancer research oncology molecular genetics tumor biology mammalian biology cancer biology molecular cancer medicinal research cancer genetics mutagenesis (molecular biology technique) chromosomal rearrangements cancer genomics cancer treatment genetic recombination medicinal chemistry molecular cell biology genome biology protein science cytogenetics recombination dynamic reproductive biology molecular neurodegeneration nucleic acids pharmacotherapy enzyme inhibition cancer care germ cell fate genome instability chromosome biology mutagenesis functional characterization genetic variant developmental cell phytotherapy research cellular therapy cancer cells knockout mice genetic mechanisms disease gene identification genetic disorders yeast animal genetics biomolecular interactions protein genetics rna biology microbial genetics herbal medicine pharmaceutical chemistry catalyst activation rational drug design anti-cancer agents functional modification epigenetic changes hyperthermia splicing variant cancer risk medical genetics meiotic prophase arrest mice deficient germline-specific reca homolog dna repair responses strand breaks telomere maintenance mutant embryos midgestation lethality affected embryos humanrad51/reca-related gene new mouse genetic mapping ofrad51d meiotic recombination pathways homology-directed repair forensic genetics chromosome instability plo biology mouse genetics developmental biology

Notable Scholarly Works

Notable Federal Grants

Collaborators

Panaxynol, a Bioactive Component of American Ginseng, Targets Macrophages and Suppresses Colitis in Mice. Oncotarget (2020)

Anusha ChaparalaDeepak PoudyalHossam TashkandiErin E. WitalisonAlexander A. ChumanevichJenna L. HofsethIvy NguyenOlivia HardyDouglas L. PittmanMichael D. WyattAnthony WindustElizabeth A. MurphyMitzi NagarkattiPrakash NagarkattiLorne J. Hofseth

pharmacologymedicinal chemistrymedicinedrug discoveryinflammationinflammatory bowel diseasephytotherapy researchbioactive compoundsimmunologymedicinal researchamerican ginsengherbal medicinebioactive component

A Mammalian Genetic Complementation Assay for Assessing Cellular Resistance to Genotoxic Compounds. Methods in molecular biology (2019)

Nicole M. ReillyDouglas L. Pittman

geneticsgenomicsmolecular biologyimmunologymammalian biologycellular resistance

Homologous Recombination-Mediated Dna Repair and Implications for Clinical Treatment of Repair Defective Cancers. Methods in molecular biology (2019)

Nicole M. ReillyBrian D. YardDouglas L. Pittman

geneticsrepair defective cancerscancer treatmentmedicinedna repaircancer researchoncologymolecular biologyclinical treatment

Potential Unintended Consequences of Getting Rigorous With Scientific Rigor. Carcinogenesis (2017)

Michael D WyattDouglas L Pittman

research ethicscancer biologyhealth sciencescancer researchcarcinogenesisscientific rigor

Thiopurine‐Induced Mitotic Catastrophe in Rad51D ‐Deficient Mammalian Cells. Environmental and Molecular Mutagenesis (2017)

Michael D. WyattNicole M. ReillyShikha PatelPreeti RajeshGary P. SchoolsPhillip G. SmiraldoDouglas L. Pittman

geneticsmutagenesisthiopurine-induced mitotic catastrophedna repaircell deathimmunologycell biologymammalian biologymutagenesis (molecular biology technique)

Homologous Recombination Preferentially Repairs Heat-Induced Dna Double-Strand Breaks in Mammalian Cells. International Journal of Hyperthermia (2016)

Akihisa TakahashiEiichiro MoriYosuke NakagawaAtsuhisa KajiharaTadaaki KiritaDouglas L. PittmanMasatoshi HasegawaTakeo Ohnishi

geneticsgenetic engineeringmembrane biologydna repairhyperthermiamammalian cellsmolecular biologycell biologyepigenetic changesmammalian biologyhomologous recombination

Rnf138 Interacts With Rad51D and is Required for Dna Interstrand Crosslink Repair and Maintaining Chromosome Integrity. DNA repair (2016)

Brian D. YardNicole M. ReillyMichael K. BedenbaughDouglas L. Pittman

geneticsdna repairradiation oncologymolecular biologychromosome integritycytogenetics

Iterative Conversion of Cyclin Binding Groove Peptides Into Druglike Cdk Inhibitors With Antitumor Activity. Journal of Medicinal Chemistry (2014)

Padmavathy Nandha PremnathSandra N. CraigShu LiuErin L. AndersonAsterios I. GrigoroudisGeorge KontopidisTracy L. PerkinsMichael D. WyattDouglas L. PittmanCampbell McInnes

iterative conversionanti-cancer agentscell biologymolecular cancerfunctional modificationtumor biologycatalyst activationpharmacologymedicinal chemistryoncologydrug deliverypharmacotherapycellular therapydrug discoveryantitumor activitydruglike cdk inhibitorspharmaceutical chemistryenzyme inhibitionmolecular biologymedicinal researchrational drug design

Video Time Lapse Imaging of Mitotic Catastrophe Events in Response to Thiopurines. The FASEB Journal (2013)

Shikha PatelDouglas Pittman

pathologymicroscopymolecular biologycell biologymitotic catastrophe events

The Homologous Recombination Protein Rad51D Mediates the Processing of 6-Thioguanine Lesions Downstream of Mismatch Repair. Molecular Cancer Research (2011)

Preeti RajeshAlexandra V. LitvinchukDouglas L. PittmanMichael D. Wyatt

geneticscancer biologymismatch repairmolecular cancercancer researchoncologyradiation oncologycancer geneticstumor biologyradiology

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Douglas Pittman

Associate Professor

University of South Carolina

Affiliations

College of Pharmacy

Department of Drug Discovery and Biomedical Sciences (ddbs)

Douglas Pittman is currently serving as a College Of Pharmacy Associate Professor at University of South Carolina.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Douglas Pittman

University of South Carolina

Associate Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Panaxynol, a Bioactive Component of American Ginseng, Targets Macrophages and Suppresses Colitis in Mice. Oncotarget (2020)

A Mammalian Genetic Complementation Assay for Assessing Cellular Resistance to Genotoxic Compounds. Methods in molecular biology (2019)

Nicole M. ReillyDouglas L. Pittman

geneticsgenomicsmolecular biologyimmunologymammalian biologycellular resistance

Homologous Recombination-Mediated Dna Repair and Implications for Clinical Treatment of Repair Defective Cancers. Methods in molecular biology (2019)

Nicole M. ReillyBrian D. YardDouglas L. Pittman

geneticsrepair defective cancerscancer treatmentmedicinedna repaircancer researchoncologymolecular biologyclinical treatment

Potential Unintended Consequences of Getting Rigorous With Scientific Rigor. Carcinogenesis (2017)

Michael D WyattDouglas L Pittman

research ethicscancer biologyhealth sciencescancer researchcarcinogenesisscientific rigor

Thiopurine‐Induced Mitotic Catastrophe in Rad51D ‐Deficient Mammalian Cells. Environmental and Molecular Mutagenesis (2017)

Michael D. WyattNicole M. ReillyShikha PatelPreeti RajeshGary P. SchoolsPhillip G. SmiraldoDouglas L. Pittman

geneticsmutagenesisthiopurine-induced mitotic catastrophedna repaircell deathimmunologycell biologymammalian biologymutagenesis (molecular biology technique)

Homologous Recombination Preferentially Repairs Heat-Induced Dna Double-Strand Breaks in Mammalian Cells. International Journal of Hyperthermia (2016)

Akihisa TakahashiEiichiro MoriYosuke NakagawaAtsuhisa KajiharaTadaaki KiritaDouglas L. PittmanMasatoshi HasegawaTakeo Ohnishi

geneticsgenetic engineeringmembrane biologydna repairhyperthermiamammalian cellsmolecular biologycell biologyepigenetic changesmammalian biologyhomologous recombination

Rnf138 Interacts With Rad51D and is Required for Dna Interstrand Crosslink Repair and Maintaining Chromosome Integrity. DNA repair (2016)

Brian D. YardNicole M. ReillyMichael K. BedenbaughDouglas L. Pittman

geneticsdna repairradiation oncologymolecular biologychromosome integritycytogenetics

Iterative Conversion of Cyclin Binding Groove Peptides Into Druglike Cdk Inhibitors With Antitumor Activity. Journal of Medicinal Chemistry (2014)

Padmavathy Nandha PremnathSandra N. CraigShu LiuErin L. AndersonAsterios I. GrigoroudisGeorge KontopidisTracy L. PerkinsMichael D. WyattDouglas L. PittmanCampbell McInnes

Video Time Lapse Imaging of Mitotic Catastrophe Events in Response to Thiopurines. The FASEB Journal (2013)

Shikha PatelDouglas Pittman

pathologymicroscopymolecular biologycell biologymitotic catastrophe events

The Homologous Recombination Protein Rad51D Mediates the Processing of 6-Thioguanine Lesions Downstream of Mismatch Repair. Molecular Cancer Research (2011)

Preeti RajeshAlexandra V. LitvinchukDouglas L. PittmanMichael D. Wyatt

geneticscancer biologymismatch repairmolecular cancercancer researchoncologyradiation oncologycancer geneticstumor biologyradiology

1
2
3
10 / page

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Similar Faculty Members

Cristina Montagna

Institution

Albert Einstein College of Medicine

carcinogenesis

developmental biology

Karen Vasquez

Institution

University of Texas at Austin

genome instability

gene targeting

Jane Skok

Institution

New York University

genome biology

genome editing

Susan M. Pinney

Institution

University of Cincinnati

environmental health

genetic epidemiology

Mario Medvedovic

Institution

University of Cincinnati

omics datasets

epigenetics

F. Huebner

Institution

Ohio State University

cancer letter

cancer risk

David Cortez

Institution

Vanderbilt University

genome maintenance

molecular cancer

Nathan Ellis

Institution

University of Arizona

cancer genetics

genetic epidemiology

Susan M. Rosenberg

Institution

Baylor College of Medicine

molecular biology

mutagenesis (molecular biology technique)

Carol L. Prives

Institution

Columbia University

molecular biology

genetics