Faculty

Institution

Unit

Venue

Dean Edwards

Professor Associate Director for Research Infrastructure

Baylor College of Medicine

Affiliations

Baylor College of Medicine Research

Dean Edwards is currently serving as a Baylor College Of Medicine Research Professor Associate Director for Research Infrastructure at Baylor College of Medicine.

Honors

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Experiences

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Education

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Dean Edwards

Baylor College of Medicine

Professor Associate Director for Research Infrastructure

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molecular biology endocrinology biochemistry receptors breast cancer hormonal receptor cell biology cell signaling pharmacology receptor (biochemistry) tumor biology oncology medicinal research cancer biology signal transduction protein science progesterone receptor molecular physiology molecular and cellular biology steroid metabolism cancer cells oncogenes breast oncology structural molecular biology molecular cell biology molecular regulation biological chemistry molecular cancer enzyme inhibition g protein-coupled receptor mammalian biology endocrine oncology cancer treatment human progesterone receptor vascular biology endocrine mechanisms endocrine-related cancers cell regulation reproductive biology psychoneuroendocrinology transcription regulation cancer genetics mammary gland reproductive immunology tumor targeting receptor tyrosine kinases cancer genomics monoclonal antibodies endocrine research signaling pathways cellular physiology antibody screening cellular biology mechanisms of action human breast cancer progesterone receptors transcriptional activity steroid hormone receptors late binding biomolecular interactions gene function rna biology immunochemistry estrogen-regulated protein mammary epithelial cells functional regulation tumor suppressors female reproductive system ovarian hormones dna binding progesterone antagonists human progesterone receptors site-specific phosphorylation estrogen receptors oncogenic mtor receptor mechanisms

Notable Scholarly Works

Notable Federal Grants

Collaborators

Structural Proteomics Defines a Sequential Priming Mechanism for the Progesterone Receptor. Nature Communications (2025)

Matthew D MannMin WangJosephine C FerreonPhoebe S TsoiMichael P SuessAntrix JainAnna MalovannayaRoberto Vera AlvarezBruce D PascalRaj KumarDean P EdwardsPatrick R Griffin

proteomicsprogesterone receptorproteome researchsequential priming mechanismstructural proteomicsmolecular biologystructural biologybiochemistry

Acetylation of Rorβ by Lysine Acetyltransferase P300 and Deacetylation by Sirt1 Modulates Receptor Stability, Turnover and Transcriptional Activity.. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Timothy O’LearyDenis ShutinDean P. EdwardsPatrick R. GriffinMi Ra Chang

gene regulationgene expressionenzyme inhibitiontranscription regulationtranscription (biology)systems biologyprotein phosphorylationchemical biologyenzymesprotein biosynthesismolecular biologyprotein expressionsignal transductionprotein sciencebiochemistrytranscriptional activity

3C. 3-Ketosteroid Receptors in Gtopdb V.2023.1. IUPHAR/BPS Guide to Pharmacology CITE (2023)

Derek CainJohn CidlowskiDean P. EdwardsPeter FullerSandra L. GrimmSean HartigCarol A. LangeRobert H. OakleyJennifer K. RicherCarol A. SartoriusMarc TetelNancy WeigelMorag J. Young

receptorspharmacologypharmacological studiesexperimental pharmacologypharmacological research

Contributors. Elsevier eBooks (2023)

International Union of Basic and Clinical Pharmacology CXIII: Nuclear Receptor Superfamily—Update 2023. Pharmacological Reviews (2023)

Thomas P. BurrisIan Mitchelle S. de VeraIsabelle CoteColin A. FlavenyUdayanga S. WanninayakeArindam ChatterjeeJohn K. WalkerNickolas SteinauerJinsong ZhangLaurel A. CoonsKenneth S. KorachDerek W. CainAnthony N. HollenbergPaul WebbDouglas ForrestAnton M. JettenDean P. EdwardsSandra L. GrimmSean HartigCarol A. LangeJennifer K. RicherCarol A. SartoriusMarc TetelCyrielle BillonBahaa ElgendyLamees HegazyKristine GriffettNahuel PeinettiKerry L. BurnsteinTravis S. HughesSadichha SitaulaKeitch R. StayrookAlexander CulverMeghan H. MurrayBrian N. FinckJohn A. Cidlowski

pharmacologyinternational union

Molecular Mechanisms of Twist1‐Regulated Transcription in Emt and Cancer Metastasis. EMBO Reports (2023)

Xiaobin YuTao HeZhangwei TongLan LiaoShixia HuangWalid D FakhouriDean P EdwardsJianming Xu

gene expressionmetastasistranscription regulationtranscription factorsmolecular biologycancer metastasismolecular mechanismscancer biologytumor biology

Profiling Histone Posttranslational Modifications and Chromatin-Modifying Proteins by High-Throughput Reverse Phase Protein Array. Elsevier eBooks (2023)

Xuan WangZhongcheng ShiNicolas L. YoungDean P. EdwardsShixia Huang

high-throughput screeningsystems biologychromatin-modifying proteinsmolecular biologyhistone posttranslational modificationschromatin remodelingchromatinstructural biologyprotein sciencebiochemistry

Supplementary Table S1-S3 From Nemo, a Transcriptional Target of Estrogen and Progesterone, is Linked to Tumor Suppressor Pml in Breast Cancer. (2023)

Hanan S. ElsarrajKelli E. ValdezYan HongSandra L. GrimmLawrence R. RicciFang FanOssama TawfikLisa MayTherese CusickMarc InciardiMark RedickJason GatewoodOnalisa WinbladSusan HilsenbeckDean P. EdwardsChristy R. HaganAndrew K. GodwinCarol FabianFariba Behbod

gene expressionpharmacologytranscription regulationendocrine oncologytranscriptional targetendocrinologygeneticstranscription factorscancer genomicsmolecular biologyoncologybreast cancermedicinal researchoncogenescancer biologycell regulation

Contributors. Elsevier eBooks (2022)

Ron AltermanJeffrey E. ArleKerry BradleySergio CanaveroSteven M. FalowskiChad W. FarleyYakov GologorskyJianwen Wendy GuH. Louis JournéeJohn KastOlga KhazenJoachim K. KraussVignessh KumarMark LentRobert M. LevyAndres M. LozanoCharles MackelGeorge T. MandyburBryan L. McLaughlinDaniel R. MerrillAlon Y. MogilnerGabi MolnarGuillermo A. MonsalveRichard B. NorthYunseo Linda ParkJohn ParkerShrey PatelJulie G. PilitsisFrancisco A. PonceJason E. PopeAdolfo Ramirez-ZamoraLouis J. RasoJoshua M. RosenowJay L. ShilsPeter SingleKonstantin V. SlavinMichael D. StaudtMark M. SteckerHuy Q. Truong

High-Throughput Profiling of Histone Post-Translational Modifications and Chromatin Modifying Proteins by Reverse Phase Protein Array. Journal of Proteomics (2022)

Xuan WangZhongcheng ShiHsin-Yi LuJean J KimWen BuJose A VillalobosDimuthu N PereraSung Yun JungTao WangSandra L GrimmBethany C TaylorKimal RajapaksheHyekyung ParkJulia WulfkuhleNicolas L YoungYi LiCristian CoarfaDean P EdwardsShixia Huang

proteomicstranslational bioinformaticssystems biologyproteome researchtranslational proteomicsprotein bioinformaticsbiomolecular engineeringhigh-throughput profilingmolecular biologystructural molecular biologyhistone post-translational modificationschromatin remodelingchromatinstructural biologychromatin modifying proteinsprotein sciencebioinformatics

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Dean Edwards

Professor Associate Director for Research Infrastructure

Baylor College of Medicine

Affiliations

Baylor College of Medicine Research

Dean Edwards is currently serving as a Baylor College Of Medicine Research Professor Associate Director for Research Infrastructure at Baylor College of Medicine.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Dean Edwards

Baylor College of Medicine

Professor Associate Director for Research Infrastructure

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Structural Proteomics Defines a Sequential Priming Mechanism for the Progesterone Receptor. Nature Communications (2025)

Matthew D MannMin WangJosephine C FerreonPhoebe S TsoiMichael P SuessAntrix JainAnna MalovannayaRoberto Vera AlvarezBruce D PascalRaj KumarDean P EdwardsPatrick R Griffin

proteomicsprogesterone receptorproteome researchsequential priming mechanismstructural proteomicsmolecular biologystructural biologybiochemistry

Acetylation of Rorβ by Lysine Acetyltransferase P300 and Deacetylation by Sirt1 Modulates Receptor Stability, Turnover and Transcriptional Activity.. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Timothy O’LearyDenis ShutinDean P. EdwardsPatrick R. GriffinMi Ra Chang

3C. 3-Ketosteroid Receptors in Gtopdb V.2023.1. IUPHAR/BPS Guide to Pharmacology CITE (2023)

Derek CainJohn CidlowskiDean P. EdwardsPeter FullerSandra L. GrimmSean HartigCarol A. LangeRobert H. OakleyJennifer K. RicherCarol A. SartoriusMarc TetelNancy WeigelMorag J. Young

receptorspharmacologypharmacological studiesexperimental pharmacologypharmacological research

Contributors. Elsevier eBooks (2023)

International Union of Basic and Clinical Pharmacology CXIII: Nuclear Receptor Superfamily—Update 2023. Pharmacological Reviews (2023)

pharmacologyinternational union

Molecular Mechanisms of Twist1‐Regulated Transcription in Emt and Cancer Metastasis. EMBO Reports (2023)

Xiaobin YuTao HeZhangwei TongLan LiaoShixia HuangWalid D FakhouriDean P EdwardsJianming Xu

gene expressionmetastasistranscription regulationtranscription factorsmolecular biologycancer metastasismolecular mechanismscancer biologytumor biology

Profiling Histone Posttranslational Modifications and Chromatin-Modifying Proteins by High-Throughput Reverse Phase Protein Array. Elsevier eBooks (2023)

Xuan WangZhongcheng ShiNicolas L. YoungDean P. EdwardsShixia Huang

high-throughput screeningsystems biologychromatin-modifying proteinsmolecular biologyhistone posttranslational modificationschromatin remodelingchromatinstructural biologyprotein sciencebiochemistry

Supplementary Table S1-S3 From Nemo, a Transcriptional Target of Estrogen and Progesterone, is Linked to Tumor Suppressor Pml in Breast Cancer. (2023)

Contributors. Elsevier eBooks (2022)

High-Throughput Profiling of Histone Post-Translational Modifications and Chromatin Modifying Proteins by Reverse Phase Protein Array. Journal of Proteomics (2022)

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