Faculty

Institution

Unit

Venue

David F. Wiemer

F Wendell Miller Professor

University of Iowa

Affiliations

College of Liberal Arts and Sciences

Chemistry Department

David F. Wiemer is currently serving as a Chemistry F Wendell Miller Professor at University of Iowa.

Honors

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Experiences

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Education

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David F. Wiemer

University of Iowa

F Wendell Miller Professor

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chemistry organic synthesis pharmacology organic chemistry chemical synthesis medicinal chemistry drug discovery biochemistry bioorganic chemistry medicine enzyme inhibition botany pharmaceutical chemistry clinical chemistry phytochemistry natural products plant science phytochemicals synthetic chemistry natural product research transition metal chemistry total synthesis pharmacotherapy medicinal research coordination chemistry stereoselective synthesis natural product synthesis derivative (chemistry) b-keto phosphonates geranylgeranyl diphosphate synthase avian biology pharmaceutical sciences insect science phytochemical analysis drug development functional modification clinical lipidology plant-insect interactions lipid chemistry pharmaceutical research potential inhibitors vinyl phosphates horner-wadsworth-emmons condensations pest science drug analysis agricultural chemistry lipid science clinical pharmacology enantioselective synthesis protein synthesis cancer biology catalytic process cytosine arabinoside biological chemistry pharmaceutics organic material chemistry active ingredient anti-inflammatory natural product biosynthesis lipoprotein metabolism biocatalysis catalyst activation biological activity isoprenoid metabolism butyrophilin ligand attine ants vinyl silane phosphates ras farnesylation piper capense leafcutter ants plasma stability lymphocyte development lymphatic system adaptive immune system t-regulatory cell cellular immune responses

Notable Scholarly Works

Notable Federal Grants

Collaborators

Benzoic Acid Derivatives Improve Plasma Stability of Diester Butyrophilin Ligand Prodrugs. Journal of Medicinal Chemistry (2026)

pharmaceutical chemistrydrug analysismedicinal chemistrybioactive compoundspharmacologypharmacological researchpharmaceutical research

Incorporation of an Alpha-Hydroxy Substituent Modulates Activity of Triazole Bisphosphonate-Based Geranylgeranyl Diphosphate Synthase Inhibitors. Bioorganic & Medicinal Chemistry (2026)

natural product researchpharmaceutical chemistryinhibitory activitymedicinal chemistrybiochemistrybioorganic chemistrypharmacologyorganic chemistryenzyme inhibitionmechanisms of action

Author Response for"Schweinfurthins and Their Analogues Are Highly Selective Cellular Probes for Oxysterol-Binding Protein". (2025)

chemical biologybiochemical sciencesaldehyde dehydrogenasebiochemistry

Synthesis and Evaluation of Triazole-Containing Aryl/Acyloxy Prodrugs of a Btn3A1 Ligand. European Journal of Medicinal Chemistry (2025)

future medicinal chemistrypharmaceutical chemistrymedicinal chemistrychemical synthesispharmacologydrug discovery

Enhanced Plasma Stability and Potency of Aryl/Acyloxy Prodrugs of a Btn3A1 Ligand. ACS Medicinal Chemistry Letters (2024)

Umed SinghGirija PawgeSarita RaniChia-Hung Christine HsiaoDavid F. WiemerAndrew J. Wiemer

plasma stabilitypharmaceutical chemistrypharmacologymedicinal chemistry

Α-Amino Bisphosphonate Triazoles Serve as Ggdps Inhibitors. Bioorganic & Medicinal Chemistry Letters (2024)

Nathaniel R. GehrkeDan FengMd. Ayub AliMona A. MaaloufSarah A. HolsteinDavid F. Wiemer

ggdps inhibitorsa-amino bisphosphonate triazolesmedicinal chemistrybioorganic chemistrypharmacology

Cationic Cascade Cyclizations Terminated by Mom Ether Derivatives of β-Keto Esters. Tetrahedron Letters (2023)

Natalie C. UlrichJose S. YuDavid F. Wiemer

cationic cascade cyclizationschemistryb-keto estersmom ether derivativesorganic synthesis

Ccdc 2157502: Experimental Crystal Structure Determination. The Cambridge Structural Database (2023)

Rao, YuPalumbo, Chad T.Venkatesh, AmritKeener, MeganStevanato, GabrieleChauvin, Anne-SophieMenzildjian, GeorgesKuzin, SergeiYulikov, MaximJeschke, GunnarLesage, AnneMazzanti, MarinellaEmsley, Lyndon

biophysicscrystal structurescrystal researchdeposited datasetstructural chemistryccdc 2157502crystal engineeringcrystallographystructure determinationstructure elucidationchemistrychemical structurecrystal diffraction study

Diester Prodrugs of a Phosphonate Butyrophilin Ligand Display Improved Cell Potency, Plasma Stability, and Payload Internalization. Journal of Medicinal Chemistry (2023)

Umed SinghGirija PawgeSarita RaniChia-Hung Christine HsiaoAndrew J. WiemerDavid F. Wiemer

diester prodrugsimmunologymedicinal chemistrypayload internalizationplasma stabilitymedicinepharmacologycell potency

Conjugate Reduction of Vinyl Bisphosphonates. Tetrahedron Letters (2022)

Nyema M. HarmonNathaniel R. GehrkeDavid F. Wiemer

conjugate reductionchemistryvinyl bisphosphonates

1
2
3
4
5
27
10 / page

David F. Wiemer

F Wendell Miller Professor

University of Iowa

Affiliations

College of Liberal Arts and Sciences

Chemistry Department

David F. Wiemer is currently serving as a Chemistry F Wendell Miller Professor at University of Iowa.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

David F. Wiemer

University of Iowa

F Wendell Miller Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Benzoic Acid Derivatives Improve Plasma Stability of Diester Butyrophilin Ligand Prodrugs. Journal of Medicinal Chemistry (2026)

pharmaceutical chemistrydrug analysismedicinal chemistrybioactive compoundspharmacologypharmacological researchpharmaceutical research

Incorporation of an Alpha-Hydroxy Substituent Modulates Activity of Triazole Bisphosphonate-Based Geranylgeranyl Diphosphate Synthase Inhibitors. Bioorganic & Medicinal Chemistry (2026)

natural product researchpharmaceutical chemistryinhibitory activitymedicinal chemistrybiochemistrybioorganic chemistrypharmacologyorganic chemistryenzyme inhibitionmechanisms of action

Author Response for"Schweinfurthins and Their Analogues Are Highly Selective Cellular Probes for Oxysterol-Binding Protein". (2025)

chemical biologybiochemical sciencesaldehyde dehydrogenasebiochemistry

Synthesis and Evaluation of Triazole-Containing Aryl/Acyloxy Prodrugs of a Btn3A1 Ligand. European Journal of Medicinal Chemistry (2025)

future medicinal chemistrypharmaceutical chemistrymedicinal chemistrychemical synthesispharmacologydrug discovery

Enhanced Plasma Stability and Potency of Aryl/Acyloxy Prodrugs of a Btn3A1 Ligand. ACS Medicinal Chemistry Letters (2024)

Umed SinghGirija PawgeSarita RaniChia-Hung Christine HsiaoDavid F. WiemerAndrew J. Wiemer

plasma stabilitypharmaceutical chemistrypharmacologymedicinal chemistry

Α-Amino Bisphosphonate Triazoles Serve as Ggdps Inhibitors. Bioorganic & Medicinal Chemistry Letters (2024)

Nathaniel R. GehrkeDan FengMd. Ayub AliMona A. MaaloufSarah A. HolsteinDavid F. Wiemer

ggdps inhibitorsa-amino bisphosphonate triazolesmedicinal chemistrybioorganic chemistrypharmacology

Cationic Cascade Cyclizations Terminated by Mom Ether Derivatives of β-Keto Esters. Tetrahedron Letters (2023)

Natalie C. UlrichJose S. YuDavid F. Wiemer

cationic cascade cyclizationschemistryb-keto estersmom ether derivativesorganic synthesis

Ccdc 2157502: Experimental Crystal Structure Determination. The Cambridge Structural Database (2023)

Rao, YuPalumbo, Chad T.Venkatesh, AmritKeener, MeganStevanato, GabrieleChauvin, Anne-SophieMenzildjian, GeorgesKuzin, SergeiYulikov, MaximJeschke, GunnarLesage, AnneMazzanti, MarinellaEmsley, Lyndon

Diester Prodrugs of a Phosphonate Butyrophilin Ligand Display Improved Cell Potency, Plasma Stability, and Payload Internalization. Journal of Medicinal Chemistry (2023)

Umed SinghGirija PawgeSarita RaniChia-Hung Christine HsiaoAndrew J. WiemerDavid F. Wiemer

diester prodrugsimmunologymedicinal chemistrypayload internalizationplasma stabilitymedicinepharmacologycell potency

Conjugate Reduction of Vinyl Bisphosphonates. Tetrahedron Letters (2022)

Nyema M. HarmonNathaniel R. GehrkeDavid F. Wiemer

conjugate reductionchemistryvinyl bisphosphonates

1
2
3
4
5
27
10 / page

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Similar Faculty Members

Daniel Romo

Institution

Baylor University

organic synthesis

chemistry

Paul R. Carlier

Institution

University of Illinois Chicago

infectious diseases (medical specialty)

malaria

Mitchell A. Avery

Institution

University of Mississippi

pharmacology

medicinal chemistry

Gordon Wayne Gribble

Institution

Dartmouth College

synthetic chemistry

natural product

Richard B. Silverman

Institution

Northwestern University

pharmacology

medicinal chemistry

Charles E. McKenna

Institution

University of Southern California

future medicinal chemistry

medicinal chemistry

Eugene A. Mash

Institution

University of Arizona

environmental chemistry

general chemistry

Hendrik Luesch

Institution

University of Florida

marine cyanobacteria

natural product biosynthesis

Iwao Ojima

Institution

Stony Brook University

organic chemistry

medicinal chemistry

Dean J Tantillo

Institution

University of California, Davis

organic chemistry

polycyclization reactions