Faculty

Institution

Unit

Venue

Joseph Collins

Research Assistant Professor

University of Florida

Affiliations

College of Pharmacy

Pharmacotherapy and Translational Research

Joseph Collins is currently serving as a College Of Pharmacy Research Assistant Professor at University of Florida.

Honors

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Experiences

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Education

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Joseph Collins

University of Florida

Research Assistant Professor

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pharmacology molecular biology gene expression medicine drug metabolism liver physiology genetics protein science pharmacological research hepatology pharmacokinetics genomics membrane biology molecular regulation human liver enzymes medicinal research transcription regulation medicinal chemistry human genetics genome biology clinical biochemistry molecular science epigenomics transcriptomics technology agricultural biotechnology plant physiology orthopaedic research oral biology bone research musculoskeletal disorders cartilage molecular cell biology mammalian biology phytochemistry plant biochemistry in-situ conversion phytochemicals bone repair bone metabolism bone homeostasis bone disease bone health cytogenetics gene regulation cell regulation gene expression profiling human tissues host specificity clinical physiology medical genetics rna biology cancer genetics metabolic regulation pharmacogenomics short-term variability biomedical research pharmaceutical sciences splicing variant allelic variant biomedical data analysis molecular analyses methionine salvage cycle glutamine transaminase medication-related osteonecrosis racial differences estrogen receptor alpha regulatory role cis-acting regulatory elements liver tissue human hepatocytes regulatory variants genome-wide microrna profiles potential underlying mechanism protein quantification total protein normalization functional genomics liver gene expression pathway analysis systems biology

Notable Scholarly Works

Notable Federal Grants

Collaborators

Dna Methylation in the Cyp3A Distal Regulatory Region (Drr) is Associated With the Expression of Cyp3A5 and Cyp3A7 in Human Liver Samples. Molecules (2024)

Joseph M. CollinsDanxin Wang

human liver samplesmolecular sciencebiochemistrymolecular biologygene expressiondna methylation

Isoform-Level Expression of the Constitutive Androstane Receptor (Car or Nr1I3) Transcription Factor Better Predicts the Mrna Expression of the Cytochrome P450S in Human Liver Samples. Drug Metabolism and Disposition (2024)

Joseph M CollinsDanxin Wang

human liver samplesisoform-level expressionmrna expressiontranscription factorspharmacologydrug metabolismconstitutive androstane receptorgene expression

A Comprehensive Evaluation of the Effects of Rna-Editing Proteins Adar and Adarb1 on the Expression of the Drug-Metabolizing Enzymes in Heparg Cells. Drug Metabolism and Disposition (2023)

Joseph M. CollinsDanxin Wang

drug developmentliver physiologydrug targetingpharmacologyclinical biochemistryrna-editing proteins adarcell biologypharmaceutical biotechnologydrug metabolismdrug discoverygene expressionheparg cellsmedicinal researchdrug-metabolizing enzymesmedicinal chemistrypharmaceutical researchcomprehensive evaluationprotein sciencepharmacokineticsmembrane biologymedicinepharmacological research

A Frequent Cyp2D6 Variant Promotes Skipping of Exon 3 and Reduces Cyp2D6 Protein Expression in Human Liver Samples. Frontiers in Pharmacology (2023)

Joseph M. CollinsHannah LesterSamia ShabnazDanxin Wang

drug metabolismprotein expressionhuman liver samplesliver physiologymolecular pharmacologypharmacokineticsmedicinemolecular biologypharmacologydrug discoverytranslational pharmacologypharmacological researchenzyme inhibitionclinical pharmacology

Quantitative Analysis of the Udp‐Glucuronosyltransferase Transcriptome in Human Tissues. Pharmacology Research & Perspectives (2023)

Lucas ZhouAbelardo D. MontalvoJoseph M. CollinsDanxin Wang

biostatisticsbiomedical data analysisproteomicsdrug analysisudp-glucuronosyltransferase transcriptometranslational medicinequantitative analysisgenomicshuman biologybiochemistrypharmacologytranscriptomics technologypharmacological researchtranscriptome

Genome-Wide Microrna Profiles Identify Mir-107 as a Top Mirna Associating With Expression of the Cyp3As and Other Drug Metabolizing Cytochrome P450 Enzymes in the Liver. Frontiers in Pharmacology (2022)

Marwa TantawyJoseph M. CollinsDanxin Wang

liver physiologypharmacologytumor biologygenomicsepigenomicsmolecular biologydrug metabolismgene expressionmedicinal researchmedical geneticsrna biologygenome biologyprotein sciencehepatologypharmacokineticsmedicinegenome-wide microrna profilespharmacological researchcancer genetics

Regulatory Variants in a Novel Distal Enhancer Regulate the Expression of Cyp3A4 and Cyp3a5. Clinical and Translational Science (2022)

Joseph M. CollinsAdaeze C. NworuSomayya J. MohammadLiang LiChengcheng LiChuanjiang LiEthan SchwendemanMattew CefaluMahmoud Abdel‐RasoulJessie W. SunSakima A. SmithDanxin Wang

regulatory variantsclinical biochemistrytranslational medicinemembrane biologyclinical physiologytranscription regulationmedicinemolecular biologypharmacologyclinical researchgene expressionmolecular regulation

Co-Expression of Drug Metabolizing Cytochrome P450 Enzymes and Estrogen Receptor Alpha (Esr1) in Human Liver: Racial Differences and the Regulatory Role of Esr1. Drug Metabolism and Personalized Therapy (2021)

Joseph M. CollinsDanxin Wang

liver physiologyracial differenceshepatologymedicinal chemistrypharmacokineticsestrogen receptor alphamedicinepharmacologydrug metabolismendocrinologyregulatory rolehuman liver

Cytochrome P450 3A4 (Cyp3A4) Protein Quantification Using Capillary Western Blot Technology and Total Protein Normalization. Journal of Pharmacological and Toxicological Methods (2021)

Joseph M. CollinsDanxin Wang

toxicologyproteomicsimmunologypharmacologypharmacological researchprotein quantificationtotal protein normalization

Esr1 Chip-Seq Identifies Distinct Ligand-Free Esr1 Genomic Binding Sites in Human Hepatocytes and Liver Tissue. International Journal of Molecular Sciences (2021)

Joseph M. CollinsZhiguang HuoDanxin Wang

functional genomicsgene expression profilingbioinformaticsgeneticscell biologygenomicsmolecular sciencehuman tissuesepigenomicsmolecular biologyliver tissuegene expressiontranscriptomics technologyhost specificitygenome biologyprotein sciencehuman hepatocyteshepatologymolecular cell biology

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Joseph Collins

Research Assistant Professor

University of Florida

Affiliations

College of Pharmacy

Pharmacotherapy and Translational Research

Joseph Collins is currently serving as a College Of Pharmacy Research Assistant Professor at University of Florida.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Joseph Collins

University of Florida

Research Assistant Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Dna Methylation in the Cyp3A Distal Regulatory Region (Drr) is Associated With the Expression of Cyp3A5 and Cyp3A7 in Human Liver Samples. Molecules (2024)

Joseph M. CollinsDanxin Wang

human liver samplesmolecular sciencebiochemistrymolecular biologygene expressiondna methylation

Joseph M CollinsDanxin Wang

human liver samplesisoform-level expressionmrna expressiontranscription factorspharmacologydrug metabolismconstitutive androstane receptorgene expression

A Comprehensive Evaluation of the Effects of Rna-Editing Proteins Adar and Adarb1 on the Expression of the Drug-Metabolizing Enzymes in Heparg Cells. Drug Metabolism and Disposition (2023)

Joseph M. CollinsDanxin Wang

A Frequent Cyp2D6 Variant Promotes Skipping of Exon 3 and Reduces Cyp2D6 Protein Expression in Human Liver Samples. Frontiers in Pharmacology (2023)

Joseph M. CollinsHannah LesterSamia ShabnazDanxin Wang

Quantitative Analysis of the Udp‐Glucuronosyltransferase Transcriptome in Human Tissues. Pharmacology Research & Perspectives (2023)

Lucas ZhouAbelardo D. MontalvoJoseph M. CollinsDanxin Wang

Marwa TantawyJoseph M. CollinsDanxin Wang

Regulatory Variants in a Novel Distal Enhancer Regulate the Expression of Cyp3A4 and Cyp3a5. Clinical and Translational Science (2022)

Joseph M. CollinsAdaeze C. NworuSomayya J. MohammadLiang LiChengcheng LiChuanjiang LiEthan SchwendemanMattew CefaluMahmoud Abdel‐RasoulJessie W. SunSakima A. SmithDanxin Wang

Joseph M. CollinsDanxin Wang

liver physiologyracial differenceshepatologymedicinal chemistrypharmacokineticsestrogen receptor alphamedicinepharmacologydrug metabolismendocrinologyregulatory rolehuman liver

Cytochrome P450 3A4 (Cyp3A4) Protein Quantification Using Capillary Western Blot Technology and Total Protein Normalization. Journal of Pharmacological and Toxicological Methods (2021)

Joseph M. CollinsDanxin Wang

toxicologyproteomicsimmunologypharmacologypharmacological researchprotein quantificationtotal protein normalization

Esr1 Chip-Seq Identifies Distinct Ligand-Free Esr1 Genomic Binding Sites in Human Hepatocytes and Liver Tissue. International Journal of Molecular Sciences (2021)

Joseph M. CollinsZhiguang HuoDanxin Wang

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Similar Faculty Members

Danxin Wang

Institution

University of Florida

molecular metabolism

pharmacology

Thomas Kocarek

Institution

Wayne State University

lipid-metabolizing enzyme

biochemistry

Philip Lazarus

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Washington State University

cancer prevention

smoking related lung disease

Robert Tukey

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University of California, San Diego

behavioral sciences

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University of Chicago

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University of Louisville

biomedical informatics

biostatistics

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David Moore

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proteomics

chemical cleavage mechanisms