Faculty

Institution

Unit

Venue

Celia W. Goulding

Chair & Professor Molecular Biology and Biochemistry Professor

University of California, Irvine

Affiliations

School of Biological Sciences

Department of Molecular Biology and Biochemistry

School of Pharmacy and Pharmaceutical Sciences

Department of Pharmaceutical Sciences

Celia W. Goulding is currently serving as a Molecular Biology And Biochemistry Chair & Professor Molecular Biology and Biochemistry Professor at University of California, Irvine.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Celia W. Goulding

University of California, Irvine

Chair & Professor Molecular Biology and Biochemistry Professor

You can click a keyword to filter the displayed items

microbiology structural biology molecular biology infectious diseases tuberculosis biochemistry protein structure microbial pathogenesis protein science clinical microbiology structural molecular biology bacteria membrane biology biomolecular structure enzymes mycobacterium tuberculosis applied microbiology biological chemistry redox biology biological inorganic chemistry veterinary medicine heme trafficking heme degradation bacteriology microbial physiology crystal structures molecular structure heme signaling heme transport pathogen transmission host-microbe interactions protein x-ray crystallography molecular microbiology x-ray crystallography respiratory medicine molecular science molecular physiology heme homeostasis protein transport protein function structural bioinformatics rna biology clinical immunology contact-dependent growth inhibition infection control biochemical sciences chemical sciences mammalian biology laboratory medicine microbial proteomics molecular research protein expression protein genetics structural genomics biomolecular interactions drug targets virus structure target highlights heme uptake inhalation toxicology host-guest chemistry respiratory infections pulmonary diseases medical microbiology bacillus calmette-guerin primary mechanism lung interstitial tissue lytic function inflamed gut bacterial pathogens structural basis potential cargo proteins iron acquisition unusual diheme conformation heme-degrading protein carbon monoxide proteomics

Notable Scholarly Works

Notable Federal Grants

Collaborators

The Structure of Mycobacterium Thermoresistibile Mmps5 Reveals a Conserved Disulfide Bond Across Mycobacteria. Metallomics (2024)

Bonnie J CuthbertJessica MendozaRodger de MirandaKadamba PapavinasasundaramChristopher M SassettiCelia W Goulding

protein structuremolecular biologymicrobiology

Abstract 1545: Elucidating Iron Transport in the Periplasm of Mycobacterium Tuberculosis. Journal of Biological Chemistry (2023)

Rodger de MirandaAlex ChaoThaís KlevornPaul SieminskiSumer Abdul-HafizSabine EhrtCelia Goulding

tuberculosisiron transportmicrobial physiologyhematologybiologybiological inorganic chemistrymycobacterium tuberculosisbiological chemistrymicrobiologybiochemistry

Differentiating the Roles of Mycobacterium Tuberculosis Substrate Binding Proteins, Fecb and Fecb2, in Iron Uptake. PLoS Pathogens (2023)

Rodger de MirandaBonnie J. CuthbertThaís KlevornAlex ChaoJessica MendozaMark ArbingPaul J. SieminskiKadamba PapavinasasundaramSumer Abdul-HafizSum ChanChristopher M. SassettiSabine EhrtCelia W. Goulding

tuberculosismicrobial pathogenesisprotein functionmicrobial physiologyinfectious diseasespathologymicrobiologyiron uptake

Author Correction: Proteolytic Processing Induces a Conformational Switch Required for Antibacterial Toxin Delivery. Nature Communications (2022)

Nicholas L. BartelliVictor J. PassanisiKarolina MichalskaKiho SongDinh Q. NhanHongjun ZhouBonnie J. CuthbertLucy M. StolsWilliam H. EschenfeldtNicholas G. WilsonJesse S. BasraRicardo CortesZainab NoorsherYoussef GabraielIsaac Poonen-HonigElizabeth C. SeacordCelia W. GouldingDavid A. LowAndrzej JoachimiakFrederick W. DahlquistChristopher S. Hayes

pharmacologybiomedical engineeringconformational switchantibacterial toxin deliveryproteolytic processingtranslational medicineauthor correction

Characterization of Periplasmic Iron Transport in Mycobacterium Tuberculosis. The FASEB Journal (2022)

Rodger de MirandaAlex ChaoPaul SieminskiSumer Abdul‐HafizCelia Goulding

public healthtuberculosispathogen transmissionmicrobial pathogenesisperiplasmic iron transporthematologyclinical microbiologyenvironmental microbiologyvirologyinfectious diseasesstructural biologymicrobiology

Functional and Structural Diversity of Bacterial Contact-Dependent Growth Inhibition Effectors. Frontiers in Molecular Biosciences (2022)

Bonnie J. CuthbertChristopher S. HayesCelia W. Goulding

immunologypathogensstructural diversitymicrobial pathogenesismicrobial physiologymolecular microbiologystructure-function enzyme kineticsclinical microbiologymolecular biologymolecular diversitystructural biologymicrobiologyhost-microbe interactions

Label-Free Affinity Screening, Design and Synthesis of Inhibitors Targeting the Mycobacterium Tuberculosis L-Alanine Dehydrogenase. PLoS ONE (2022)

Heung-Bok KimJohn-Paul BacikRuilian WuRamesh K. JhaMichaeline HebronCatherine TriandafillouJoseph E. McCownNam-In BaekJeong Han KimYoung Jae KimCelia W. GouldingCharlie E. M. StraussJurgen G. SchmidtGauri S. ShetyeSungweon RyooEun-Kyeong JoYoung Ho JeonLi-Wei HungThomas C. TerwilligerChang-Yub Kim

immunologymedicinal chemistryenzyme inhibitionpharmacologyrational drug designmolecular pharmacologymolecular pharmingbiomolecular engineeringenzymesdrug discoveryprotein synthesismedicinal researchprotein designlabel-free affinity screening

Metabolic Fluxes for Nutritional Flexibility of Mycobacterium Tuberculosis. Molecular Systems Biology (2021)

Khushboo BorahTom A MendumNathaniel D HawkinsJane L WardMichael H BealeGerald Larrouy‐MaumusApoorva BhattMartine MoulinMichael HaertleinGernot StrohmeierHarald PichlerV Trevor ForsythStephan NoackCelia W GouldingJohnjoe McFaddenDany J V Beste

tuberculosismicrobial physiologysystems biologymetabolic fluxesnutritional flexibilityinfectious diseasesmetabolismmicrobiology

Metabolic Flux Partitioning Between the Tca Cycle and Glyoxylate Shunt Combined With a Reversible Methyl Citrate Cycle Provide Nutritional Flexibility for Mycobacterium Tuberculosis. bioRxiv (Cold Spring Harbor Laboratory) (2021)

Khushboo BorahTom A. MendumNathaniel D. HawkinsJane L. WardMichael H. BealeGerald Larrouy-MaumusApoorva BhattMartine MoulinMichael HaertleinGernot StrohmeierHarald PichlerV. Trevor ForsythStephen NoackCelia W. GouldingJohnjoe McFaddenDany J.V. Beste

public healthtuberculosisglyoxylate shuntmolecular microbiologytca cycleclinical microbiologynutritional flexibilityinfectious diseasesmetabolic fluxmicrobiology

An Optimized Chemical-Genetic Method for Cell-Specific Metabolic Labeling of Rna. Nature Methods (2020)

Sarah NainarBonnie J. CuthbertNathan M. LimWhitney E. EnglandKe KeKanika SophalRobert QuecholDavid L. MobleyCelia W. GouldingRobert C. Spitale

genomicstranscriptomics technologygeneticsoptimized chemical-genetic methodmolecular biologycell-specific metabolic labelingrna biologybiological engineeringbioinformatics

1
2
3
4
5
8
10 / page

Celia W. Goulding

Chair & Professor Molecular Biology and Biochemistry Professor

University of California, Irvine

Affiliations

School of Biological Sciences

Department of Molecular Biology and Biochemistry

School of Pharmacy and Pharmaceutical Sciences

Department of Pharmaceutical Sciences

Celia W. Goulding is currently serving as a Molecular Biology And Biochemistry Chair & Professor Molecular Biology and Biochemistry Professor at University of California, Irvine.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Celia W. Goulding

University of California, Irvine

Chair & Professor Molecular Biology and Biochemistry Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

The Structure of Mycobacterium Thermoresistibile Mmps5 Reveals a Conserved Disulfide Bond Across Mycobacteria. Metallomics (2024)

Bonnie J CuthbertJessica MendozaRodger de MirandaKadamba PapavinasasundaramChristopher M SassettiCelia W Goulding

protein structuremolecular biologymicrobiology

Abstract 1545: Elucidating Iron Transport in the Periplasm of Mycobacterium Tuberculosis. Journal of Biological Chemistry (2023)

Rodger de MirandaAlex ChaoThaís KlevornPaul SieminskiSumer Abdul-HafizSabine EhrtCelia Goulding

tuberculosisiron transportmicrobial physiologyhematologybiologybiological inorganic chemistrymycobacterium tuberculosisbiological chemistrymicrobiologybiochemistry

Differentiating the Roles of Mycobacterium Tuberculosis Substrate Binding Proteins, Fecb and Fecb2, in Iron Uptake. PLoS Pathogens (2023)

tuberculosismicrobial pathogenesisprotein functionmicrobial physiologyinfectious diseasespathologymicrobiologyiron uptake

Author Correction: Proteolytic Processing Induces a Conformational Switch Required for Antibacterial Toxin Delivery. Nature Communications (2022)

pharmacologybiomedical engineeringconformational switchantibacterial toxin deliveryproteolytic processingtranslational medicineauthor correction

Characterization of Periplasmic Iron Transport in Mycobacterium Tuberculosis. The FASEB Journal (2022)

Rodger de MirandaAlex ChaoPaul SieminskiSumer Abdul‐HafizCelia Goulding

Functional and Structural Diversity of Bacterial Contact-Dependent Growth Inhibition Effectors. Frontiers in Molecular Biosciences (2022)

Bonnie J. CuthbertChristopher S. HayesCelia W. Goulding

Label-Free Affinity Screening, Design and Synthesis of Inhibitors Targeting the Mycobacterium Tuberculosis L-Alanine Dehydrogenase. PLoS ONE (2022)

Metabolic Fluxes for Nutritional Flexibility of Mycobacterium Tuberculosis. Molecular Systems Biology (2021)

tuberculosismicrobial physiologysystems biologymetabolic fluxesnutritional flexibilityinfectious diseasesmetabolismmicrobiology

public healthtuberculosisglyoxylate shuntmolecular microbiologytca cycleclinical microbiologynutritional flexibilityinfectious diseasesmetabolic fluxmicrobiology

An Optimized Chemical-Genetic Method for Cell-Specific Metabolic Labeling of Rna. Nature Methods (2020)

Sarah NainarBonnie J. CuthbertNathan M. LimWhitney E. EnglandKe KeKanika SophalRobert QuecholDavid L. MobleyCelia W. GouldingRobert C. Spitale

genomicstranscriptomics technologygeneticsoptimized chemical-genetic methodmolecular biologycell-specific metabolic labelingrna biologybiological engineeringbioinformatics

1
2
3
4
5
8
10 / page

Similar Faculty Members

Malcolm Winkler

Institution

Indiana University Bloomington

molecular biology

microbiology

Tina Iverson

Institution

Vanderbilt University

structural biology

covid

Benfang Lei

Institution

Montana State University

microbiology

immunology

David P. Giedroc

Institution

Indiana University Bloomington

emerging infectious disease

pathogen

Robert Clubb

Institution

University of California, Los Angeles

virulence factors

microbial pathogenesis

Michael A. Marletta

Institution

University of California, Berkeley

biochemistry

enzymes

Matthew Redinbo

Institution

University of North Carolina at Chapel Hill

gut microbial pathogens

microbiology

Deborah Tan Hung

Institution

Harvard University

clinical microbiology

microbial pathogenesis

Parastoo Azadi

Institution

University of Georgia

polysaccharide

glycosylation

Walter Chazin

Institution

Vanderbilt University

molecular biology

proteomics

Similar Faculty Members

Malcolm Winkler

Institution

Indiana University Bloomington

molecular biology

microbiology

Tina Iverson

Institution

Vanderbilt University

structural biology

covid

Benfang Lei

Institution

Montana State University

microbiology

immunology

David P. Giedroc

Institution

Indiana University Bloomington

emerging infectious disease

pathogen

Robert Clubb

Institution

University of California, Los Angeles

virulence factors

microbial pathogenesis

Michael A. Marletta

Institution

University of California, Berkeley

biochemistry

enzymes

Matthew Redinbo

Institution

University of North Carolina at Chapel Hill

gut microbial pathogens

microbiology

Deborah Tan Hung

Institution

Harvard University

clinical microbiology

microbial pathogenesis

Parastoo Azadi

Institution

University of Georgia

polysaccharide

glycosylation

Walter Chazin

Institution

Vanderbilt University

molecular biology

proteomics