Faculty

Institution

Unit

Venue

Bassel E. Sawaya

Professor

Temple University

Affiliations

Lewis Katz School of Medicine

Basic Science Departments

Clinical Departments

Basic Science Departments

Cancer and Cellular Biology

Clinical Departments

Neurology

Bassel E. Sawaya is currently serving as a Basic Science S Professor at Temple University.

Honors

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Experiences

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Education

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Bassel E. Sawaya

Temple University

Professor

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hiv immunology virology genetics neuroscience gene expression general virology viral genetics virus research cell biology transcription regulation molecular virology neurovirology virus-host interactions medical virology viral pathogenesis cell signaling gene regulation human retrovirus immune responses transcription factors signal transduction protein science medicinal research cell regulation oncogenes molecular regulation brain science cell cycle cellular biology cellular physiology mammalian biology cellular biochemistry antiviral research protein expression molecular immunology redox biology biological chemistry molecular cell biology cytokines cell physiology viral replication viral evolution clinical neuroscience molecular physiology liver physiology protein function viral structural protein neuroprotection cellular neurobiology cancer genetics cancer biology andrology gene regulatory networks host factors gene function viral oncology human astrocytes glial cells human transferrin gene genome biology neuroinflammation protein phosphorylation cooperative interaction metabolic reprogramming cell cycle progression novel protein human brain cells astrocytic cells hiv-associated neurocognitive disorders oxidative stress pathway viral genome p21waf1 gene promoter tnf alpha production cooperative actions viral gene transcription

Notable Scholarly Works

Notable Federal Grants

Collaborators

From Envelope to Encephalopathy: How Hiv-1 Gp120 Drives Neurocognitive Decline. Viruses (2026)

cognitive neurosciencehivneurologyneuropsychologyneurovirologyneuroimmunologybrain healthhuman retroviruscognitive impairmentmolecular neurodegenerationneuroscience of agingbrain functioncognitive scienceneuroscienceneurodegenerative diseases

Hiv-1 Gp120 Exposure Associates With Mitochondrial and Pkm Remodeling in Cardiomyocytes. AIDS (2026)

physiologyhivimmunologyhiv-1 gp120 exposureinflammationcell signalingcardiovascular researchmitochondrial functionhuman retroviruscell metabolismcell biology

Hiv-1 Tat-Induced Vapb Disruption Initiates a Cascade of Organellar Failures Culminating in Neuronal Lipid Accumulation. Journal of Lipid Research (2026)

immunologyhivmedical virologycell signalinggeneral virologyorganellar failuresneuronal lipid accumulationhuman retrovirusantiviral responsesimmune responsesinfectious diseasescell biology

Hiv Vpr Induces Demethylation of the Snca Antisense Promoter, Leading to Neurocognitive Impairment. Scientific Reports (2026)

neurologyhivhiv vprmedical virologyneurocognitive impairmentmolecular neurosciencehuman retrovirusantiviral responsesmolecular neurodegenerationsnca antisense promoterneuroscienceneurodegenerative diseases

Lipid Dysregulation as a Convergent Pathway Linking Environmental Exposures to Stroke. Frontiers in Aging Neuroscience (2026)

physiologyneurologydyslipidemiaclinical lipidologyischemic syndromelipid dysregulationlipoprotein metabolismthrombosislipidsvascular biologyenvironmental exposuresconvergent pathwaycerebral blood flowstrokelipid disordersinflammation

Memory Disorders Across Neuropsychiatric Conditions: A Unified Mechanistic Framework for Precision Intervention. (2026)

cognitive neurosciencememory lossprecision interventionunified mechanistic frameworkneuropsychological rehabilitationmemory studiesmemory disorderspsychiatrytranslational psychiatrycognitive scienceneuropsychiatrymemoryneurosciencecognition

Memory Impairments: Type, Causes, and Molecular Players—Memory Dysfunction Across Neurologic Insults. Cells (2026)

neurologymemory lossmemory impairmentsmemory assessmentcognitive impairmentmolecular neurodegenerationneuroscience of agingcognitive sciencememoryneuroscienceneurodegenerative diseases

Microbiota as a Regulator of Brain Vulnerability Across Lifespan and Disease Contexts. Journal of Neuroinflammation (2026)

microbiomeneurologygut microbesageingexperimental gerontologygut-organ axisaging-associated diseasesbrain vulnerabilitydisease contextsbrain healthneuroscienceneuroscience of agingdysbiosismicrobiologyneurodegenerative diseases

Ck1δ-Dependent Snapin Dysregulation Drives Lysosomal Failure in Hiv-1 Vpr-Exposed Neurons: A Targetable Mechanism in Hand. iScience (2025)

hivtargetable mechanismcell signalingmolecular neurosciencemolecular and cellular biologymolecular cell biologyhuman retrovirusmolecular biologymolecular neurodegenerationimmune responsesantiviral responseshiv-1 vpr-exposed neuronscell biology

Mitochondria‐Associated Membranes ( Mams ): Molecular Organization, Cellular Functions, and Their Role in Health and Disease. FEBS Open Bio (2025)

cellular functionsmitochondrial dynamicscellular physiologymembranesfree radical biologyredox biologymolecular and cellular biologymitochondrial functionmolecular biologymembrane proteinscell and molecular biologymembrane sciencemitochondrial biogenesismitophagyorganelle dynamicsmolecular organizationmembrane biologycell biology

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Bassel E. Sawaya

Professor

Temple University

Affiliations

Lewis Katz School of Medicine

Basic Science Departments

Clinical Departments

Basic Science Departments

Cancer and Cellular Biology

Clinical Departments

Neurology

Bassel E. Sawaya is currently serving as a Basic Science S Professor at Temple University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Bassel E. Sawaya

Temple University

Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

From Envelope to Encephalopathy: How Hiv-1 Gp120 Drives Neurocognitive Decline. Viruses (2026)

Hiv-1 Gp120 Exposure Associates With Mitochondrial and Pkm Remodeling in Cardiomyocytes. AIDS (2026)

physiologyhivimmunologyhiv-1 gp120 exposureinflammationcell signalingcardiovascular researchmitochondrial functionhuman retroviruscell metabolismcell biology

Hiv-1 Tat-Induced Vapb Disruption Initiates a Cascade of Organellar Failures Culminating in Neuronal Lipid Accumulation. Journal of Lipid Research (2026)

immunologyhivmedical virologycell signalinggeneral virologyorganellar failuresneuronal lipid accumulationhuman retrovirusantiviral responsesimmune responsesinfectious diseasescell biology

Hiv Vpr Induces Demethylation of the Snca Antisense Promoter, Leading to Neurocognitive Impairment. Scientific Reports (2026)

Lipid Dysregulation as a Convergent Pathway Linking Environmental Exposures to Stroke. Frontiers in Aging Neuroscience (2026)

Memory Disorders Across Neuropsychiatric Conditions: A Unified Mechanistic Framework for Precision Intervention. (2026)

Memory Impairments: Type, Causes, and Molecular Players—Memory Dysfunction Across Neurologic Insults. Cells (2026)

neurologymemory lossmemory impairmentsmemory assessmentcognitive impairmentmolecular neurodegenerationneuroscience of agingcognitive sciencememoryneuroscienceneurodegenerative diseases

Microbiota as a Regulator of Brain Vulnerability Across Lifespan and Disease Contexts. Journal of Neuroinflammation (2026)

Ck1δ-Dependent Snapin Dysregulation Drives Lysosomal Failure in Hiv-1 Vpr-Exposed Neurons: A Targetable Mechanism in Hand. iScience (2025)

Mitochondria‐Associated Membranes ( Mams ): Molecular Organization, Cellular Functions, and Their Role in Health and Disease. FEBS Open Bio (2025)

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virus research

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general virology

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viral infections

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