Faculty

Institution

Unit

Venue

Barbara Slack

Associate Professor Pathology & Laboratory Medicine

Boston University

Affiliations

Chobanian & Avedisian School of Medicine

Basic Science Departments

Graduate Medical Sciences

Basic Science Departments

Pathology & Laboratory Medicine

Barbara Slack is currently serving as a Basic Science S Associate Professor Pathology & Laboratory Medicine at Boston University.

Honors

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Experiences

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Education

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Barbara Slack

Boston University

Associate Professor Pathology & Laboratory Medicine

You can click a keyword to filter the displayed items

neuroscience pharmacology neurology alzheimer's disease biochemistry protein science neurochemistry neuropharmacology cell signaling membrane biology signal transduction neurodegenerative diseases receptors neurophysiology molecular physiology redox biology biochemical sciences medicinal research molecular neurobiology cellular neurobiology brain science biological chemistry mammalian biology receptor (biochemistry) molecular neurodegeneration cellular biochemistry cell metabolism human sciences brain function protein phosphorylation clinical neuroscience molecular science brain imaging brain pathology receptor tyrosine kinases mitochondrial function host factors cancer biology cell regulation lipid preparation lipid synthesis brain circuitry membrane defect phosphatidylcholine synthesis cholinergic neurons differential regulation human neuroblastoma cells biomedical imaging pharmacological research cell death cellular physiology enzyme inhibition brain structure neuroprotection animal genetics biogerontology mechanisms of action pharmacokinetics protein secretion functional regulation neuroinflammation pathway analysis degenerative disease secretory pathway enzyme specificity muscarinic acetylcholine receptors alzheimer disease brain dietary choline neuroprotective actions constitutive shedding phorbol esters genetic model behavioral gerontology receptor isoform displays tyrosine phosphorylation-dependent stimulation neuronal cells signal transduction pathways protein function cell biology g protein-coupled receptor proteome research

Notable Scholarly Works

Notable Federal Grants

Collaborators

Accelerated Breakdown of Phosphatidylcholine and Phosphatidylethanolamine is a Predominant Brain Metabolic Defect in Alzheimer’s Disease. Journal of Alzheimer s Disease (2023)

Jan Krzysztof BlusztajnBarbara E. Slack

alzheimer's diseaseneurochemistryneuropharmacologyphysiologycognitive neuroscienceneurosciencebrain scienceneurophysiologyclinical neurosciencemolecular neurosciencehealth sciencesbrain circuitrybrain function

Neuroprotective Actions of Dietary Choline. Nutrients (2017)

Jan Krzysztof BlusztajnBarbara E SlackTiffany J Mellott

neuroprotectiondietary cholineneuroscienceneuroprotective actionscentral nervous system

Bmp9 Ameliorates Amyloidosis and the Cholinergic Defect in a Mouse Model of Alzheimer’s Disease. Proceedings of the National Academy of Sciences (2013)

Rebecca M. BurkeTimothy A. NormanTarik F. HaydarBarbara E. SlackSusan E. LeemanJan Krzysztof BlusztajnTiffany J. Mellott

neuropharmacologymolecular neurobiologyneurosciencegeneticsalzheimer's diseaseneurogeneticshuman sciencesmolecular scienceneurodegenerative diseasesmolecular neuroscienceneurochemistrymolecular neurodegenerationmouse modelmedicinal researchpathway analysisdegenerative diseaseneurologyprotein sciencecholinergic defectmammalian biology

The Extracellular Regulated Kinase-1 (Erk1) Controls Regulated α-Secretase-Mediated Processing, Promoter Transactivation, and Mrna Levels of the Cellular Prion Protein.. Journal of Biological Chemistry (2013)

Moustapha CisséEric DuplanMarie-Victoire Guillot-SestierJoaquim RumignyCharlotte BauerGilles PagèsHans-Dieter OrzechowskiBarbara E. SlackFrédéric CheclerBruno Vincent

cellular prion proteincell signalingcell biologybiochemistrymolecular biologypromoter transactivationmrna levels

F-Spondin/Spon1B Expression Patterns in Developing and Adult Zebrafish. PLoS ONE (2012)

Veronica AkleEmmanuel GuelinLili YuHelena Brassard-GiordanoBarbara E. SlackIrina V. Zhdanova

adult zebrafishfish biologydevelopmental biologymolecular biologygene expressiongenetics

Surface Expression and Limited Proteolysis of Adam10 Are Increased by a Dominant Negative Inhibitor of Dynamin. BMC Cell Biology (2011)

Robyn M CareyJan K BlusztajnBarbara E Slack

limited proteolysisprotein sciencecell biologyneurosciencemembrane biologydominant negative inhibitorpharmacologysurface expression

Zebrafish as a Genetic Model in Biological and Behavioral Gerontology: Where Development Meets Aging in Vertebrates – a Mini-Review. Gerontology (2009)

Shuji KishiBarbara E. SlackJunzo UchiyamaIrina V. Zhdanova

animal geneticsbiogerontologygenetic modelbiologyevolutionary biologypopulation geneticsgeneticsbehavioral gerontology

Differential Regulation of Mtor‐Dependent S6 Phosphorylation by Muscarinic Acetylcholine Receptor Subtypes. Journal of Cellular Biochemistry (2008)

Barbara E. SlackJan K. Blusztajn

differential regulationendocrinologyprotein phosphorylationprotein sciencecell signalingredox biologybiochemistryreceptor (biochemistry)molecular physiologymolecular regulationmolecular biologypharmacologysignal transductiongene expressionreceptorscellular biochemistryhost specificity

Isoform-Specific Contribution of Protein Kinase C to Prion Processing. Molecular and Cellular Neuroscience (2008)

Moustapha Alfa CisséKrystel LouisUschi BraunBernard MariMichael LeitgesBarbara E. SlackAbraham FisherPatrick AubergerFrédéric CheclerBruno Vincent

biophysicsneurochemistrycellular neurobiologyprion processingisoform-specific contributionmolecular neurobiologyneurosciencebrain sciencemolecular basismolecular biologymolecular neuroscience

O4‐06–01: App and Prpc Physiological Metabolisms Are Both Controlled by Muscarinic Receptors via Adam17 Phosphorylation. Alzheimer s & Dementia (2008)

Bruno VincentMoustapha Alfa CisséClaire SunyachBarbara E. SlackAbraham FisherFrédéric Checler

neurologyalzheimer's diseaseprpc physiological metabolismsneurosciencepharmacologydementiamuscarinic receptors

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Barbara Slack

Associate Professor Pathology & Laboratory Medicine

Boston University

Affiliations

Chobanian & Avedisian School of Medicine

Basic Science Departments

Graduate Medical Sciences

Basic Science Departments

Pathology & Laboratory Medicine

Barbara Slack is currently serving as a Basic Science S Associate Professor Pathology & Laboratory Medicine at Boston University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Barbara Slack

Boston University

Associate Professor Pathology & Laboratory Medicine

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Accelerated Breakdown of Phosphatidylcholine and Phosphatidylethanolamine is a Predominant Brain Metabolic Defect in Alzheimer’s Disease. Journal of Alzheimer s Disease (2023)

Jan Krzysztof BlusztajnBarbara E. Slack

Neuroprotective Actions of Dietary Choline. Nutrients (2017)

Jan Krzysztof BlusztajnBarbara E SlackTiffany J Mellott

neuroprotectiondietary cholineneuroscienceneuroprotective actionscentral nervous system

Bmp9 Ameliorates Amyloidosis and the Cholinergic Defect in a Mouse Model of Alzheimer’s Disease. Proceedings of the National Academy of Sciences (2013)

Rebecca M. BurkeTimothy A. NormanTarik F. HaydarBarbara E. SlackSusan E. LeemanJan Krzysztof BlusztajnTiffany J. Mellott

Moustapha CisséEric DuplanMarie-Victoire Guillot-SestierJoaquim RumignyCharlotte BauerGilles PagèsHans-Dieter OrzechowskiBarbara E. SlackFrédéric CheclerBruno Vincent

cellular prion proteincell signalingcell biologybiochemistrymolecular biologypromoter transactivationmrna levels

F-Spondin/Spon1B Expression Patterns in Developing and Adult Zebrafish. PLoS ONE (2012)

Veronica AkleEmmanuel GuelinLili YuHelena Brassard-GiordanoBarbara E. SlackIrina V. Zhdanova

adult zebrafishfish biologydevelopmental biologymolecular biologygene expressiongenetics

Surface Expression and Limited Proteolysis of Adam10 Are Increased by a Dominant Negative Inhibitor of Dynamin. BMC Cell Biology (2011)

Robyn M CareyJan K BlusztajnBarbara E Slack

limited proteolysisprotein sciencecell biologyneurosciencemembrane biologydominant negative inhibitorpharmacologysurface expression

Zebrafish as a Genetic Model in Biological and Behavioral Gerontology: Where Development Meets Aging in Vertebrates – a Mini-Review. Gerontology (2009)

Shuji KishiBarbara E. SlackJunzo UchiyamaIrina V. Zhdanova

animal geneticsbiogerontologygenetic modelbiologyevolutionary biologypopulation geneticsgeneticsbehavioral gerontology

Differential Regulation of Mtor‐Dependent S6 Phosphorylation by Muscarinic Acetylcholine Receptor Subtypes. Journal of Cellular Biochemistry (2008)

Barbara E. SlackJan K. Blusztajn

Isoform-Specific Contribution of Protein Kinase C to Prion Processing. Molecular and Cellular Neuroscience (2008)

Moustapha Alfa CisséKrystel LouisUschi BraunBernard MariMichael LeitgesBarbara E. SlackAbraham FisherPatrick AubergerFrédéric CheclerBruno Vincent

biophysicsneurochemistrycellular neurobiologyprion processingisoform-specific contributionmolecular neurobiologyneurosciencebrain sciencemolecular basismolecular biologymolecular neuroscience

O4‐06–01: App and Prpc Physiological Metabolisms Are Both Controlled by Muscarinic Receptors via Adam17 Phosphorylation. Alzheimer s & Dementia (2008)

Bruno VincentMoustapha Alfa CisséClaire SunyachBarbara E. SlackAbraham FisherFrédéric Checler

neurologyalzheimer's diseaseprpc physiological metabolismsneurosciencepharmacologydementiamuscarinic receptors

1
2
3
4
5
10 / page

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stem cell

endothelial function

Stephen Moss

Institution

Tufts University

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molecular biology

molecular cell biology

Eugenia V. Gurevich

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biomedical informatics

translational data science

Eric Klann

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health science

cardiovascular translational research

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clinical proteomics

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