Faculty

Institution

Unit

Venue

Alan Brash

Professor

Vanderbilt University

Affiliations

Graduate School

Chemical and Physical Biology

School of Medicine

Department of Pharmacology

Alan Brash is currently serving as a Chemical And Physical Biology Professor at Vanderbilt University.

Honors

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Experiences

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Education

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Alan Brash

Vanderbilt University

Professor

You can click a keyword to filter the displayed items

Video Presentations

Notable Scholarly Works

Notable Federal Grants

Collaborators

Analysis of the Thiol Adduction of Linoleate 9,10-Dihydroxy-11 E -13-Ketones of the Mammalian Skin Barrier and Their Cyclization to Hemiketals. ACS Omega (2025)

drug metabolismskin developmentoxidative stresscosmetic dermatologyskin pharmacologydermatologydermal structuremammalian skin barrierbioactive compoundsin vitro toxicologybiochemistrytheir cyclizationcutaneous biologythiol adduction

The Effects of Naturally Occurring Mutations on Functionality of Oxylipin Metabolizing Dehydrogenase Reductase Nine. Journal of Biological Chemistry (2025)

redox biologyaldehyde dehydrogenasealcohol dehydrogenasesenzymesbiochemical geneticsbiochemistrymolecular biologycell metabolismmolecular metabolismbiological chemistryenzyme inhibitionmutagenesis (molecular biology technique)metabolismgeneticsbiochemical sciencesdehydrogenase reductase 9

The Origin of Hydroxy-Cyclohexenone Fatty Acids From Skin Barrier Protein and Relevance to Covalent Binding of Ceramides. Journal of Lipid Research (2025)

lipidshydroxy-cyclohexenone fatty acidslipid chemistrymembrane proteinsmembrane biologyskin pharmacologydermatologybiological macromoleculesskin barrier proteinbiochemistrybiomoleculescutaneous biology

CORRECTION: Two C18 Hydroxy-Cyclohexenone Fatty Acids From Mammalian Epidermis: Potential Relation to 12R-Lipoxygenase and Covalent Binding of Ceramides. Journal of Biological Chemistry (2024)

Alan R. BrashSaori NoguchiWilliam E. BoeglinM. Wade CalcuttDonald F. StecClaus SchneiderJason M. Meyer

mammalian biologybiologychemical biologymammalian epidermishydroxy-cyclohexenone fatty acidsmolecular biologybiological chemistrycovalent bindingavian biologybiochemistry

Fatty Acids of Helicobacter Pylori Lipoproteins Cagt and Lpp20. Microbiology Spectrum (2024)

Mark S. McClainWilliam E. BoeglinHolly M. Scott AlgoodAlan R. Brash

bacteriologymicrobiologyfatty acidsclinical microbiologymedical microbiologybacteriainfectious diseases

Heme-Catalyzed Degradation of Linoleate 9-Hydroperoxide (9-Hpode) Forms Two Allylic Epoxy-Ketones via a Proposed Pseudo-Symmetrical Diepoxy Radical Intermediate. Free Radical Research (2024)

Saori NoguchiWilliam E. BoeglinNed A. PorterAlan R. Brash

chemistryheme-catalyzed degradationallylic epoxy-ketones

The Michael Addition of Thiols to 13-Oxo-Octadecadienoate (13-Oxo-Ode) With Implications for Lc-Ms Analysis of Glutathione Conjugation. Journal of Biological Chemistry (2024)

William E. BoeglinDonald F. StecSaori NoguchiM. Wade CalcuttAlan R. Brash

chemical biologylc-ms analysisglutathione conjugationmolecular biologybiological chemistrybiochemistrymichael addition

The Octadecanoids: Synthesis and Bioactivity of 18-Carbon Oxygenated Fatty Acids in Mammals, Bacteria, and Fungi. Chemical Reviews (2024)

Johanna Revol-CavalierAlessandro QuarantaJohn W. NewmanAlan R. BrashMats HambergCraig E. Wheelock

redox biologyecotoxicologyexperimental toxicologyfine chemicalsenvironmental engineeringlipid nutritionenzymesmembrane biologychemical safetygene expressionmicrobiologynanoparticle researchclinical lipidologyenzyme inhibitionbiosensorsphotocatalysisbiological engineeringlipid resource

718 Identification of Lipid-Peptide Adducts of the 12R-Lipoxygenase Pathway in Human and Murine Corneocyte Lipid Envelopes. Journal of Investigative Dermatology (2023)

lipidspeptidescellular biochemistrylipid analysis12r-lipoxygenase pathwaylipid-peptide adductsbiochemistrylipoprotein metabolismbiomolecular engineeringmetabolismcell metabolism

773 Purified Recombinant Pnpla1 Catalyzes the Synthesis of Acylceramides and Acylacids of the Mammalian Skin Barrier. Journal of Investigative Dermatology (2023)

chemical biologydermatological treatmentpurified recombinant pnpla1skin pharmacologymammalian skin barrierdermatologybioorganic chemistrybiomolecular engineeringmedicinal chemistrybiomoleculescutaneous biology

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Alan Brash

Professor

Vanderbilt University

Affiliations

Graduate School

Chemical and Physical Biology

School of Medicine

Department of Pharmacology

Alan Brash is currently serving as a Chemical And Physical Biology Professor at Vanderbilt University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Alan Brash

Vanderbilt University

Professor

You can click a keyword to filter the displayed items

Video Presentations

Notable Scholarly Works

Notable Federal Grants

Collaborators

Analysis of the Thiol Adduction of Linoleate 9,10-Dihydroxy-11 E -13-Ketones of the Mammalian Skin Barrier and Their Cyclization to Hemiketals. ACS Omega (2025)

The Effects of Naturally Occurring Mutations on Functionality of Oxylipin Metabolizing Dehydrogenase Reductase Nine. Journal of Biological Chemistry (2025)

The Origin of Hydroxy-Cyclohexenone Fatty Acids From Skin Barrier Protein and Relevance to Covalent Binding of Ceramides. Journal of Lipid Research (2025)

CORRECTION: Two C18 Hydroxy-Cyclohexenone Fatty Acids From Mammalian Epidermis: Potential Relation to 12R-Lipoxygenase and Covalent Binding of Ceramides. Journal of Biological Chemistry (2024)

Alan R. BrashSaori NoguchiWilliam E. BoeglinM. Wade CalcuttDonald F. StecClaus SchneiderJason M. Meyer

mammalian biologybiologychemical biologymammalian epidermishydroxy-cyclohexenone fatty acidsmolecular biologybiological chemistrycovalent bindingavian biologybiochemistry

Fatty Acids of Helicobacter Pylori Lipoproteins Cagt and Lpp20. Microbiology Spectrum (2024)

Mark S. McClainWilliam E. BoeglinHolly M. Scott AlgoodAlan R. Brash

bacteriologymicrobiologyfatty acidsclinical microbiologymedical microbiologybacteriainfectious diseases

Heme-Catalyzed Degradation of Linoleate 9-Hydroperoxide (9-Hpode) Forms Two Allylic Epoxy-Ketones via a Proposed Pseudo-Symmetrical Diepoxy Radical Intermediate. Free Radical Research (2024)

Saori NoguchiWilliam E. BoeglinNed A. PorterAlan R. Brash

chemistryheme-catalyzed degradationallylic epoxy-ketones

The Michael Addition of Thiols to 13-Oxo-Octadecadienoate (13-Oxo-Ode) With Implications for Lc-Ms Analysis of Glutathione Conjugation. Journal of Biological Chemistry (2024)

William E. BoeglinDonald F. StecSaori NoguchiM. Wade CalcuttAlan R. Brash

chemical biologylc-ms analysisglutathione conjugationmolecular biologybiological chemistrybiochemistrymichael addition

The Octadecanoids: Synthesis and Bioactivity of 18-Carbon Oxygenated Fatty Acids in Mammals, Bacteria, and Fungi. Chemical Reviews (2024)

Johanna Revol-CavalierAlessandro QuarantaJohn W. NewmanAlan R. BrashMats HambergCraig E. Wheelock

718 Identification of Lipid-Peptide Adducts of the 12R-Lipoxygenase Pathway in Human and Murine Corneocyte Lipid Envelopes. Journal of Investigative Dermatology (2023)

lipidspeptidescellular biochemistrylipid analysis12r-lipoxygenase pathwaylipid-peptide adductsbiochemistrylipoprotein metabolismbiomolecular engineeringmetabolismcell metabolism

773 Purified Recombinant Pnpla1 Catalyzes the Synthesis of Acylceramides and Acylacids of the Mammalian Skin Barrier. Journal of Investigative Dermatology (2023)

1
2
3
4
5
40
10 / page

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Stephen Barnes

Institution

University of Alabama at Birmingham

pharmacology

health sciences

Lawrence J. Marnett

Institution

Vanderbilt University

anti-inflammatory agent

biochemistry

Claus Schneider

Institution

Vanderbilt University

lipids

phytochemistry

Daniel Liebler

Institution

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proteomic biomarkers

translational proteomics

Sanjay Srivastava

Institution

University of Louisville

volatile organic compounds

free radical biology

Salvatore Vincent Pizzo

Institution

Duke University

pharmacology

biochemistry

Anthony E. Pegg

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cancer letter

toxicological mechanism

Shantu Amin

Institution

Pennsylvania State University

cancer letter

polycyclic aromatic hydrocarbon

Tadashi Inagami

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cardiovascular disease

hypertension

Neil Kaplowitz, MD

Institution

University of Southern California

hepatotoxicity

toxicological aspect