Zachary Working

Oregon Health & Science University

Affiliations

Oregon Health & Science University

Zachary Working is a Senior Professor at Oregon Health & Science University specializing in orthopaedic surgery and traumatology. His research focuses on fracture healing, trauma surgery, and rehabilitation, with particular emphasis on severe open tibia fractures, geriatric distal femur fractures, and composite musculoskeletal injuries. His recent work includes a randomized controlled trial comparing antibiotic cement bead pouch versus negative pressure wound therapy for severe open tibia fractures, engineered muscle-driven bone repair, and the efficacy of biomarkers in endochondral fracture repair. He has also investigated the impact of home call on sleep among orthopaedic surgeons. His publications appear in leading journals including BMJ Open, Biomaterials, the Journal of Bone and Joint Surgery, and the Journal of the American Academy of Orthopaedic Surgeons.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Zachary Working

Oregon Health & Science University

You can click a keyword to filter the displayed items

orthopaedic surgery orthopedic surgery trauma bone fracture orthopaedic research trauma surgery surgery skeletal trauma traumatology rehabilitation fracture healing musculoskeletal disorders epidemiology arthroplasty knee surgery bone research bone repair pelvic trauma biomechanics regenerative medicine osteoarthritis outcomes research upper extremity spinal fracture orthopedic biomechanics surgical stabilization distal femur fractures risk factors biomarkers joint replacement musculoskeletal imaging musculoskeletal research magnetic resonance imaging soft tissue injuries computed tomography periprosthetic femur fracture radiographic investigation distal extension articular surface tibial plateau fractures multicenter study respiratory medicine fracture mechanics transgender health arthritis cartilage forensic toxicology addiction medicine applied pharmacology addiction biology pharmacological research diabetes care cementation radiographic imaging non-operative management sport injuries shoulder girdle gender transitions ankle trauma lower limb trauma tendon injuries bone remodeling polytrauma bone imaging club drugs psychoactive drugs bone disease non-operative treatment total hip arthroplasty femoral fixation fiberglass casts biomechanical comparison quantitative serum biomarker biologic progression current status multicenter experience

Notable Scholarly Works

Notable Federal Grants

Collaborators

Engineered Muscle Drives Bone Repair and Functional Healing After Composite Musculoskeletal Injury. Biomaterials (2026)

tissue engineeringregeneration (biology)composite musculoskeletal injurybone researchorthopaedic surgeryfracture healingregenerative medicinebiomedical engineeringbone repairfunctional tissue engineeringsynthetic bone substituteengineered muscle drivesmusculoskeletal disorderssoft tissue injuriesfunctional healing

ERRATUM: Home Call and Sleep in Orthopaedic Surgeons. a Prospective, Longitudinal Study of the Effect of Home Call on Sleep in Orthopaedic Attending Surgeons and Residents. Journal of Bone and Joint Surgery (2026)

Postoperative Weight-Bearing Status is Not Associated With Patient Mortality After Geriatric Distal Femur Fracture. Journal of the American Academy of Orthopaedic Surgeons (2026)

Randomised Controlled Trial Comparing Antibiotic Cement Bead Pouch Versus Negative Pressure Wound Therapy for the Management of Severe Open Tibia Fracture Wounds: Beads Versus Vac (Bvv) Protocol. BMJ Open (2026)

orthopaedic researchintensive caretraumamedicinewound healingknee surgerysurgeryorthopedic surgeryarthroplastyorthopaedic surgeryhospital infectionsreconstructive microsurgerybone fractureantibioticspatient safetymicrosurgerycritical care clinic

The Key and the Door: Universal Concepts of Reduction in Fracture Surgery. Journal of the American Academy of Orthopaedic Surgeons (2026)

Anterior and Posterior Fixation Versus Posterior Fixation Only of Minimally Displaced Lateral Compression Type 1 Pelvic Ring Injuries: A Multicenter Propensity-Matched Analysis. Injury (2025)

pelvic traumatraumaknee surgerysurgeryorthopedic surgerysurgical stabilization

Efficacy of Biomarkers in the Endochondral Phase of Fracture Repair and Healing in Long Bones: A Clinical Observational Studys. PLoS Medicine (2025)

orthopaedic researchfracture repairmedicinebone researchclinical observational studysorthopedic surgeryorthopaedic surgeryfracture healingbone fractureregenerative medicinemusculoskeletal researchbone diseasebone repairlong bonesbiomarkers

Fracture Nonunions. OTA International The Open Access Journal of Orthopaedic Trauma (2025)

Home Call and Sleep in Orthopaedic Surgeons. Journal of Bone and Joint Surgery (2025)

Increased Associated Risk of Postoperative Periprosthetic Femur Fracture With Cementless Versus Cemented Hemiarthroplasty: A Nationwide Database Study of 24,419 Femoral Neck Fractures. OTA International The Open Access Journal of Orthopaedic Trauma (2025)