Faculty

Institution

Unit

Venue

Yukai He

Professor

Augusta University

Affiliations

Medical College of Georgia

Department of Medicine

Yukai He is currently serving as a Medicine Professor at Augusta University.

Honors

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Experiences

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Education

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Yukai He

Augusta University

Professor

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immunology oncology cancer immunotherapy medicinal research cancer research medicine tumor biology immune responses clinical immunology pharmacology immunotherapy cellular therapy cancer biology hepatocellular carcinoma dermatology adaptive immune system cancer care cancer treatment liver cancer molecular cancer gene expression tumor targeting t-regulatory cell gene therapy experimental medicine leukemia tumor suppressors viral oncology cancer genetics cellular immune responses cancer cells lentivector immunization medical mycology cell regulation tumor heterogeneity cancer genomics anti-cancer agents cancer immunosurveillance antitumor effect mammalian biology pharmacotherapy enzyme inhibition vaccine research recombinant lentivector oncogenes thoracic oncology vascular biology molecular diagnostics catalyst activation gene delivery therapeutic efficacy cancer growth viral genetics vaccine development tgfb signalling simultaneous overactivation dendritic cells naked dna antitumor efficacy antitumor immunity systemic administration molecular cell biology redox signaling hemostasis innate immune system knockout mice signaling pathways disease progression gene editing histocompatibility tumor-draining lymph nodes oncolytic viruses therapeutic cancer vaccines cancer vaccines skin-derived dendritic cells naive mice cell therapy pathology cell transplantation immunomodulation

Notable Scholarly Works

Notable Federal Grants

Collaborators

Rac1-Amplified and Rac1-A159V Hotspot-Mutated Head and Neck Cancer Sensitive to the Rac Inhibitor Ehop-016 in Vivo: A Proof-Of-Concept Study. Cancers (2025)

Helen Hoi Yin ChanHoi-Lam NganYuen-Keng NgChun-Ho LawPeony Hiu Yan PoonRay Wai Wa ChanKwok-Fai LauWenying PiaoHui LiLan WangJason Ying Kuen ChanYu-Xiong SuThomas Chun Kit YeungEileen WongAngela Wing Tung LiKrista Roberta VerhoeftYuchen LiuYukai HeStephen Kwok-Wing TsuiGordon B. MillsVivian Wai Yan Lui

neck cancer sensitivecancer researchcancer discoverymolecular biologycancer geneticsproof-of-concept studyoncologycancer biology

A Novel Engineered Il-21 Receptor Arms T-Cell Receptor-Engineered T Cells (Tcr-T Cells) Against Hepatocellular Carcinoma. Signal Transduction and Targeted Therapy (2024)

Wei ZhuZhiming ZhangJinzhang ChenXiaolan ChenLei HuangXiaoyong ZhangXuan HuangNa MaWeikang XuXuan YiXinyu LuXin FuSiwei LiGuoheng MoYiyue WangGuosheng YuanMengya ZangQi LiXiaotao JiangYajing HeSha WuYukai HeYongyin LiJinlin Hou

drug targetingimmunologypharmacologyadaptive immune systemcancer immunotherapynovel therapiesimmunotherapycancer researchpharmacotherapyhepatocellular carcinomamedicinal researchcellular therapytcr-t cellstumor targetingbiomedical engineeringexperimental medicinesignal transductionpharmacological researchoncology

Tcr-T Cells for Cancer Immunotherapy. Elsevier eBooks (2024)

Mohamed Shawky HusseinRui MaoYukai He

cancer immunotherapyimmunologytcr-t cellsimmunotherapy

A Personal Tribute to Dr. Harald Zur Hausen: A Distinguished Scientist and Caring Mentor. Journal of Medical Virology (2023)

Yukai He

diagnostic virologyvirologyharald zur hausendistinguished scientistcaring mentormentorshipmedicinemedical virologygeneral virologyvirus research

Combination of Afp Vaccine and Immune Checkpoint Inhibitors Slows Hepatocellular Carcinoma Progression in Preclinical Models. Journal of Clinical Investigation (2023)

Xinjun LuShanshan DengJiejie XuBenjamin L. GreenHonghua ZhangGuofei CuiYi ZhouYi ZhangHongwei XuFapeng ZhangRui MaoSheng ZhongThorsten CramerMatthias EvertDiego F. CalvisiYukai HeChao LiuXin Chen

hepatocellular carcinoma progressiondermatologycarcinogenesispharmacologyvaccinationvaccine trialsclinical chemistryafp vaccinecancer treatmenthealth sciencesclinical evaluationtranslational medicinemedicinal researchclinical investigationcancer careclinical trialspreclinical modelsmetastasisliver cancerliver diseaseexperimental medicine

Data From the Antitumor Effects of Vaccine-Activated Cd8 Sup + /Sup T Cells Associate With Weak Tcr Signaling and Induction of Stem-Like Memory T Cells. (2023)

Sha WuWei ZhuYibing PengLan WangYuan HongLei HuangDayong DongJunping XieTodd MerchenEdward KruseZong Sheng GuoDavid BartlettNing FuYukai He

vaccinest-regulatory cellcancer immunotherapycell signalingvaccinationimmunologymedicinal researchcellular therapyvaccine researchimmune responsescellular immune responsesmedicinepharmacologyadaptive immune systemantitumor effectscytokines

Tcr T Cells Overexpressing C-Jun Have Better Functionality With Improved Tumor Infiltration and Persistence in Hepatocellular Carcinoma. Frontiers in Immunology (2023)

Mohamed S. HusseinQi LiRui MaoYibing PengYukai He

pathologyliver cancercancer immunotherapyimmunopathologyimmunologymedicinal researchdermatologycellular therapycarcinogenesiscancer researchimmune responsestumor suppressorscancer cellshepatocellular carcinomacancer careoncologycancer biology

206 Novel Intermediate-Avidity Glypican-3 Specific Carts Resist Exhaustion and Mediate Durable Antitumor Effects Against Human Hepatocellular Carcinoma. Regular and Young Investigator Award Abstracts (2022)

Leidy Caraballo-GalvaXiaotao JiangMohamed HusseinHuajun ZhangRui MaoPierce BrodyYibing PengAIwu HeMercy Kehinde-IgeRamses SadekXiangguo QiuHuidong ShiYukai He

anti-cancer agentsimmunologydermatologypharmacologytherapeutic targetscancer immunotherapyenzyme inhibitioncancer researchcancer treatmenthepatocellular carcinomamedicinal researchclinical investigationcellular therapydrug resistancetumor targetingoncologyexperimental medicineanticoagulantshuman hepatocellular carcinoma

Chimeric Antigen Receptor Engineered T Cells and Their Application in the Immunotherapy of Solid Tumours. Expert Reviews in Molecular Medicine (2022)

Rui MaoMohamed S. HusseinYukai He

solid tumourscancer immunotherapyimmunologymolecular medicinemedicinal researchimmunotherapychimeric antigen receptorbiomedical engineeringmedicineexperimental medicineclinical researchclinical immunologycancer biology

Contributors. Elsevier eBooks (2022)

Ron AltermanJeffrey E. ArleKerry BradleySergio CanaveroSteven M. FalowskiChad W. FarleyYakov GologorskyJianwen Wendy GuH. Louis JournéeJohn KastOlga KhazenJoachim K. KraussVignessh KumarMark LentRobert M. LevyAndres M. LozanoCharles MackelGeorge T. MandyburBryan L. McLaughlinDaniel R. MerrillAlon Y. MogilnerGabi MolnarGuillermo A. MonsalveRichard B. NorthYunseo Linda ParkJohn ParkerShrey PatelJulie G. PilitsisFrancisco A. PonceJason E. PopeAdolfo Ramirez-ZamoraLouis J. RasoJoshua M. RosenowJay L. ShilsPeter SingleKonstantin V. SlavinMichael D. StaudtMark M. SteckerHuy Q. Truong

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Yukai He

Professor

Augusta University

Affiliations

Medical College of Georgia

Department of Medicine

Yukai He is currently serving as a Medicine Professor at Augusta University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Yukai He

Augusta University

Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Rac1-Amplified and Rac1-A159V Hotspot-Mutated Head and Neck Cancer Sensitive to the Rac Inhibitor Ehop-016 in Vivo: A Proof-Of-Concept Study. Cancers (2025)

neck cancer sensitivecancer researchcancer discoverymolecular biologycancer geneticsproof-of-concept studyoncologycancer biology

A Novel Engineered Il-21 Receptor Arms T-Cell Receptor-Engineered T Cells (Tcr-T Cells) Against Hepatocellular Carcinoma. Signal Transduction and Targeted Therapy (2024)

Tcr-T Cells for Cancer Immunotherapy. Elsevier eBooks (2024)

Mohamed Shawky HusseinRui MaoYukai He

cancer immunotherapyimmunologytcr-t cellsimmunotherapy

A Personal Tribute to Dr. Harald Zur Hausen: A Distinguished Scientist and Caring Mentor. Journal of Medical Virology (2023)

Yukai He

diagnostic virologyvirologyharald zur hausendistinguished scientistcaring mentormentorshipmedicinemedical virologygeneral virologyvirus research

Combination of Afp Vaccine and Immune Checkpoint Inhibitors Slows Hepatocellular Carcinoma Progression in Preclinical Models. Journal of Clinical Investigation (2023)

Xinjun LuShanshan DengJiejie XuBenjamin L. GreenHonghua ZhangGuofei CuiYi ZhouYi ZhangHongwei XuFapeng ZhangRui MaoSheng ZhongThorsten CramerMatthias EvertDiego F. CalvisiYukai HeChao LiuXin Chen

Data From the Antitumor Effects of Vaccine-Activated Cd8 Sup + /Sup T Cells Associate With Weak Tcr Signaling and Induction of Stem-Like Memory T Cells. (2023)

Sha WuWei ZhuYibing PengLan WangYuan HongLei HuangDayong DongJunping XieTodd MerchenEdward KruseZong Sheng GuoDavid BartlettNing FuYukai He

Tcr T Cells Overexpressing C-Jun Have Better Functionality With Improved Tumor Infiltration and Persistence in Hepatocellular Carcinoma. Frontiers in Immunology (2023)

Mohamed S. HusseinQi LiRui MaoYibing PengYukai He

Leidy Caraballo-GalvaXiaotao JiangMohamed HusseinHuajun ZhangRui MaoPierce BrodyYibing PengAIwu HeMercy Kehinde-IgeRamses SadekXiangguo QiuHuidong ShiYukai He

Chimeric Antigen Receptor Engineered T Cells and Their Application in the Immunotherapy of Solid Tumours. Expert Reviews in Molecular Medicine (2022)

Rui MaoMohamed S. HusseinYukai He

Contributors. Elsevier eBooks (2022)

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medicine

Sherven Sharma

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University of California, Los Angeles

oncology

cancer research

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Ohio State University

biomedical informatics

systems biology

Steven M. Dubinett

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immune response

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pathology

cancer cell

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gene therapy

cell therapy

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oncology

brain tumor research