Faculty

Institution

Unit

Venue

Yuan Lu

Case Western Reserve University

Affiliations

Medicine

Cardiovascular Medicine

School of Medicine

Medicine

NoneYuan Lu is currently serving as a Cardiovascular Medicine faculty at Case Western Reserve University.

Honors

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Experiences

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Education

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Yuan Lu

Case Western Reserve University

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physiology cardiology hematology membrane biology vascular biology cell biology genetics health sciences gene expression cellular physiology liver physiology endocrinology clinical research regenerative medicine clinical investigation molecular physiology cardiovascular research nephrology mammalian biology angiology experimental medicine thrombosis animal physiology chronobiology functional regulation cell metabolism respiratory medicine clinical lipidology medicinal research hemostasis clinical physiology molecular regulation arterial disease cardiovascular physiology cell physiology mammalian physiology tissue physiology cerebrovascular disease bile acid synthesis circadian control vascular inflammation kruppel-like factors arterial thrombosis cellular biochemistry laboratory medicine clinical medicine cell regulation transcription regulation mitochondrial function gene regulation translational physiology cardiovascular translational research molecular basis blood pressure cardiovascular function cardiac muscle microvascular dysfunction neurovascular diseases genetic factors biogerontology vascular aging lifespan extension nematology glucocorticoids mitophagy vascular integrity circadian nitrogen homeostasis cardiac mitochondrial homeostasis transcriptional control aortic aneurysm formation molecular link pressure-induced cardiac hypertrophy cardiac fibroblasts kruppel-like factor podocyte differentiation markers cold challenge

Notable Scholarly Works

Notable Federal Grants

Collaborators

Klf15 Controls Brown Adipose Tissue Transcriptional Flexibility and Metabolism in Response to Various Energetic Demands. iScience (2022)

Liyan FanAlexander F. LesserDavid R. SweetKomal S. KeerthyYuan LuErnest R. ChanVinesh VinayachandranOlga IlkayevaTapatee DasChristopher B. NewgardMukesh K. Jain

physiologyliver physiologyenergy homeostasisgene expressionenergy metabolismcellular physiologymetabolic regulationsystems biologyendocrinologytranscription (biology)molecular metabolismphysiological regulationmolecular biologymetabolismmolecular physiologymembrane biology

Tissue-Specific Expression of Myosin Phosphatase Subunits and Isoforms in Smooth Muscle of Mice and Humans. AJP Regulatory Integrative and Comparative Physiology (2022)

Kimberly OslinJohn J. RehoYuan LuSunita KhanalDoreswamy KenchegowdaSteven J. PriorSteven A. Fisher

mammalian physiologycomparative physiologyhuman biologycell biologyprotein sciencemembrane biologycellular physiologyanimal physiologymammalian biologytissue physiologymolecular physiologyphysiologytissue-specific expressionsmooth musclehuman physiologymolecular biologymyosin phosphatase subunitsprotein expressionneurophysiology

CORRECTION: The Thromboprotective Effect of Traditional Chinese Medicine Tongji 2 Granules is Dependent on Anti-Inflammatory Activity by Suppression of Nf-κB Pathways. PLoS ONE (2021)

Lin ZhouStephanie LappingXudong LiaoYuan LuGuangjin ZhouKeiichiro MatobaNeelakantan T VasudevanLemin WangNone Lalitha Nayak

immunologynf-kb pathwaysthromboprotective effecttraditional chinese medicineanti-inflammatory activityinflammation

Muscle KrüPpel-Like Factor 15 Regulates Lipid Flux and Systemic Metabolic Homeostasis. Journal of Clinical Investigation (2021)

Liyan FanDavid R. SweetDomenick A. ProsdocimoVinesh VinayachandranErnest R. ChanRongli ZhangOlga IlkayevaYuan LuKomal S. KeerthyChloe E. BoothChristopher B. NewgardMukesh K. Jain

physiologyliver physiologysystemic metabolic homeostasisclinical lipidologycellular physiologyhematologynephrologyendocrinologygeneticsclinical researchclinical physiologyclinical investigationmolecular physiologyhealth sciences

Myeloid KrüPpel-Like Factor 2 is a Critical Regulator of Metabolic Inflammation. Nature Communications (2020)

David R. SweetNeelakantan T. VasudevanLiyan FanChloe E. BoothKomal S. KeerthyXudong LiaoVinesh VinayachandranYoichi TakamiDerin TugalNikunj SharmaE. Ricky ChanLilei ZhangYulan QingStanton L. GersonChen FuAnthony Wynshaw-BorisPanjamaporn SangwungLalitha NayakPaul HolvoetKeiichiro MatobaYuan LuGuangjin ZhouMukesh K. Jain

physiologyhematologygeneticsmetabolic inflammationcritical regulator

Mitophagy is Required for Brown Adipose Tissue Mitochondrial Homeostasis During Cold Challenge. Scientific Reports (2018)

Yuan LuHisashi FujiokaDinesh JoshiQiaoyuan LiPanjamaporn SangwungPaishiun HsiehJiyun ZhuJose TorioDavid SweetLan WangShing Yan ChiuColleen CronigerXudong LiaoMukesh K. Jain

physiologymolecular biologymitophagyhealth sciencescold challenge

A Conserved Klf-Autophagy Pathway Modulates Nematode Lifespan and Mammalian Age-Associated Vascular Dysfunction. Nature Communications (2017)

Paishiun N. HsiehGuangjin ZhouYiyuan YuanRongli ZhangDomenick A. ProsdocimoPanjamaporn SangwungAnna H. BortonEvgenii BoriushkinAnne HamikHisashi FujiokaCiaran E. FealyJohn P. KirwanMaureen PetersYuan LuXudong LiaoDiana Ramírez-BergeronZhaoyang FengMukesh K. Jain

ageinglongevityavian biologybiogerontologyanimal physiologysystems biologyvascular biologymammalian physiologymammalian biologyvascular aginglifespan extensionnematologyhuman biologygeriatricsecologyautophagymembrane biologyevolutionary biology

Adipose Klf15 Controls Lipid Handling to Adapt to Nutrient Availability. Cell Reports (2017)

Keiichiro MatobaYuan LuRongli ZhangEric R. ChenPanjamaporn SangwungBenlian WangDomenick A. ProsdocimoMukesh K. Jain

nutrient availabilitymolecular and cellular biologygeneticsabiotic stressbiochemistrycell biology

Klf2 and Klf4 Control Endothelial Identity and Vascular Integrity. JCI Insight (2017)

Panjamaporn SangwungGuangjin ZhouLalitha NayakE. Ricky ChanSandeep KumarDong-Won KangRongli ZhangXudong LiaoYuan LuKeiki SugiHisashi FujiokaHong ShiStephanie D. LappingChandra C. GhoshSarah J. HigginsSamir M. ParikhHanjoong JoMukesh K. Jain

physiologycardiologyhematologyvascular biologyangiologyvascular integrity

Regulation of Endothelial Hemoglobin Alpha Expression by Kruppel-Like Factors. Vascular Medicine (2017)

Panjamaporn SangwungGuangjin ZhouYuan LuXudong LiaoBenlian WangStephanie M MutchlerMegan MillerMark R ChanceAdam C StraubMukesh K Jain

physiologydermatologygene expressionhematologyvascular biologygeneticsmolecular regulationkruppel-like factorsmembrane biology

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Yuan Lu

Case Western Reserve University

Affiliations

Medicine

Cardiovascular Medicine

School of Medicine

Medicine

NoneYuan Lu is currently serving as a Cardiovascular Medicine faculty at Case Western Reserve University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Yuan Lu

Case Western Reserve University

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Klf15 Controls Brown Adipose Tissue Transcriptional Flexibility and Metabolism in Response to Various Energetic Demands. iScience (2022)

Liyan FanAlexander F. LesserDavid R. SweetKomal S. KeerthyYuan LuErnest R. ChanVinesh VinayachandranOlga IlkayevaTapatee DasChristopher B. NewgardMukesh K. Jain

Tissue-Specific Expression of Myosin Phosphatase Subunits and Isoforms in Smooth Muscle of Mice and Humans. AJP Regulatory Integrative and Comparative Physiology (2022)

Kimberly OslinJohn J. RehoYuan LuSunita KhanalDoreswamy KenchegowdaSteven J. PriorSteven A. Fisher

CORRECTION: The Thromboprotective Effect of Traditional Chinese Medicine Tongji 2 Granules is Dependent on Anti-Inflammatory Activity by Suppression of Nf-κB Pathways. PLoS ONE (2021)

Lin ZhouStephanie LappingXudong LiaoYuan LuGuangjin ZhouKeiichiro MatobaNeelakantan T VasudevanLemin WangNone Lalitha Nayak

immunologynf-kb pathwaysthromboprotective effecttraditional chinese medicineanti-inflammatory activityinflammation

Muscle KrüPpel-Like Factor 15 Regulates Lipid Flux and Systemic Metabolic Homeostasis. Journal of Clinical Investigation (2021)

Liyan FanDavid R. SweetDomenick A. ProsdocimoVinesh VinayachandranErnest R. ChanRongli ZhangOlga IlkayevaYuan LuKomal S. KeerthyChloe E. BoothChristopher B. NewgardMukesh K. Jain

Myeloid KrüPpel-Like Factor 2 is a Critical Regulator of Metabolic Inflammation. Nature Communications (2020)

physiologyhematologygeneticsmetabolic inflammationcritical regulator

Mitophagy is Required for Brown Adipose Tissue Mitochondrial Homeostasis During Cold Challenge. Scientific Reports (2018)

Yuan LuHisashi FujiokaDinesh JoshiQiaoyuan LiPanjamaporn SangwungPaishiun HsiehJiyun ZhuJose TorioDavid SweetLan WangShing Yan ChiuColleen CronigerXudong LiaoMukesh K. Jain

physiologymolecular biologymitophagyhealth sciencescold challenge

A Conserved Klf-Autophagy Pathway Modulates Nematode Lifespan and Mammalian Age-Associated Vascular Dysfunction. Nature Communications (2017)

Adipose Klf15 Controls Lipid Handling to Adapt to Nutrient Availability. Cell Reports (2017)

Keiichiro MatobaYuan LuRongli ZhangEric R. ChenPanjamaporn SangwungBenlian WangDomenick A. ProsdocimoMukesh K. Jain

nutrient availabilitymolecular and cellular biologygeneticsabiotic stressbiochemistrycell biology

Klf2 and Klf4 Control Endothelial Identity and Vascular Integrity. JCI Insight (2017)

physiologycardiologyhematologyvascular biologyangiologyvascular integrity

Regulation of Endothelial Hemoglobin Alpha Expression by Kruppel-Like Factors. Vascular Medicine (2017)

Panjamaporn SangwungGuangjin ZhouYuan LuXudong LiaoBenlian WangStephanie M MutchlerMegan MillerMark R ChanceAdam C StraubMukesh K Jain

physiologydermatologygene expressionhematologyvascular biologygeneticsmolecular regulationkruppel-like factorsmembrane biology

1
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cardiovascular biology

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