Faculty

Institution

Unit

Venue

Young-In Chi, PhD

Assistant Professor Department of Surgery; Research Scientist Linda T and John A Mellowes Center for Genomic Sciences and Precision Medicine

Medical College of Wisconsin

Affiliations

Department of Surgery

Young-in Chi, Phd is currently serving as a Surgery Assistant Professor Department of Surgery; Research Scientist Linda T and John A Mellowes Center for Genomic Sciences and Precision Medicine at Medical College of Wisconsin.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Young-In Chi, PhD

Medical College of Wisconsin

Assistant Professor Department of Surgery; Research Scientist Linda T and John A Mellowes Center for Genomic Sciences and Precision Medicine

You can click a keyword to filter the displayed items

molecular biology structural biology structural molecular biology protein structure biochemistry biomolecular structure genetics cell biology molecular cell biology gene expression transcription factors molecular and cellular biology protein science enzymes biological macromolecules molecular structure protein x-ray crystallography cancer biology disease gene identification biological chemistry medicinal research mutagenesis (molecular biology technique) liver physiology molecular physiology nucleic acids genetic disorders crystal structures signal transduction molecular recognition rna biology transcription regulation cancer genomics biochemical sciences clinical microbiology molecular regulation gene regulation cell regulation rna structure prediction signaling pathways gene function enzyme inhibition cell metabolism structural chemistry metabolic regulation nuclear organization cancer growth molecular basis x-ray crystallography disease mechanisms genomic mechanisms structural basis structural bioinformatics apoptosis tumor targeting anti-cancer agents toxinology molecular complexes structure elucidation cellular structure insulin secretion adipose triglyceride lipase truncated form histocompatibility cancer prevention three-dimensional structure molecular hook snag domain nuclear lamin wild type disulphide bond hammerhead ribozyme structures disease-causing mutations hnf-4α activation phenylalanine zipper zinc-mediated dimerization multiple binding modes x-ray diffraction protein modeling

Notable Scholarly Works

Notable Federal Grants

Collaborators

Abstract 2504 Phosphorylation of Prmt5-Mep50 Methylosome Regulates Cytoplasmic Stress Granule Formation in Pancreatic Cancer. Journal of Biological Chemistry (2025)

abstract 2504molecular and cellular biologytumor biologycell signalingcell biologymolecular cell biologyautophagypancreatic cancersystems biologycancer cellscell regulationcellular biochemistrycancer biology

Abstract 2539 Defining the Molecular Heterogeneity and Functional Impact of Pancreatic Cancer-Associated Kras Mutations. Journal of Biological Chemistry (2025)

oncogenessomatic variantpathologytumor biologymolecular heterogeneitycell biologymolecular cancercarcinogenesisabstract 2539cancer researchmolecular diagnosticspancreatic cancerfunctional impactcancer cellscancer geneticscancer genomics

Computational Structural Genomics and Clinical Evidence Suggest Bckdk Gain-Of-Function May Cause a Potentially Asymptomatic Maple Syrup Urine Disease Phenotype.. Epigenomics (2025)

proteome researchgenomicsdisease gene identificationcomputational structural genomicsmolecular diagnosticsclinical proteomicssystems biologyhuman geneticsmedical geneticsbioinformaticsgenetics

Genomic Features of the Methylosome Protein Mep50 and Its Implication in Hormone Signaling and Cancer. Endocrine Connections (2025)

oncogeneschromatin remodelingmethylosome protein mep50hormone signalingcell biologyepigeneticsgenomic featurescarcinogenesismolecular cell biologyepigenomicscancer cellsgene expressioncancer geneticscancer genomicsgenetics

Mutational Landscapes of Hnf Mody Gene Products Display a Wide Distribution With Functional Implications. Endocrine Connections (2025)

protein geneticsmutagenesis (molecular biology technique)wide distributionfunctional implicationsgenomic mechanismsfunctional genomicsgenomicsgenome biologymolecular geneticsgene characterizationmolecular biologyhereditymutational landscapesgenetic mechanismsgenetics

Computational Structural Genomics and Clinical Evidence Suggest Bckdk Gain‐of‐Function May Cause a Potentially Asymptomatic Maple Syrup Urine Disease Phenotype. JIMD Reports (2024)

Emily SinghYoung‐In ChiJessica KopeskyMichael ZimmermanRaul UrrutiaDonald BaselJessica Scott Schwoerer

computational biologygenomicsstructural genomicscomputational structural genomicscomputational genomicsbioinformaticsgenetics

Emergent Properties of the Lysine Methylome Reveal Regulatory Roles via Protein Interactions and Histone Mimicry. Epigenomics (2024)

Gareth PollinYoung-In ChiAngela J. MathisonMichael T. ZimmermannGwen LomberkRaul Urrutia

protein interactionshistone mimicryepigenomicsmolecular biology

A Multi-Layered Computational Structural Genomics Approach Enhances Domain-Specific Interpretation of Kleefstra Syndrome Variants in Ehmt1. Computational and Structural Biotechnology Journal (2023)

computational biologybiomedical informaticsgenetic disorderskleefstra syndrome variantsdomain-specific interpretationcomplex diseasesgenome biologyvariant interpretationmolecular informaticsmolecular geneticsdisease gene identificationsystems biologyhuman geneticsmedical geneticsbioinformaticsgenetics

A Multi-Layered Computational Structural Genomics Approach Enhances Domain-Specific Interpretation of Kleefstra Syndrome Variants in Ehmt1. bioRxiv (Cold Spring Harbor Laboratory) (2023)

Young-In ChiSalomão D. JorgeDavin R. JensenBrian C. SmithBrian F. VolkmanAngela J. MathisonGwen LomberkMichael T. ZimmermannRaul Urrutia

kleefstra syndrome variantsdomain-specific interpretationgenomicsstructural genomicsmolecular biologycomputational genomics

Deep Computational Phenotyping of Genomic Variants Impacting the Set Domain of Kmt2C Reveal Molecular Mechanisms for Their Dysfunction. Frontiers in Genetics (2023)

Salomão Dória JorgeYoung-In ChiJose Lizarraga MazabaNeshatul HaqueJessica WagenknechtBrian C. SmithBrian F. VolkmanAngela J. MathisonGwen LomberkMichael T. ZimmermannRaul Urrutia

deep computational phenotypinggenomic mechanismsset domaingenomicsgenomic variantsgenetics

1
2
3
4
5
9
10 / page

Young-In Chi, PhD

Assistant Professor Department of Surgery; Research Scientist Linda T and John A Mellowes Center for Genomic Sciences and Precision Medicine

Medical College of Wisconsin

Affiliations

Department of Surgery

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Young-In Chi, PhD

Medical College of Wisconsin

Assistant Professor Department of Surgery; Research Scientist Linda T and John A Mellowes Center for Genomic Sciences and Precision Medicine

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Abstract 2504 Phosphorylation of Prmt5-Mep50 Methylosome Regulates Cytoplasmic Stress Granule Formation in Pancreatic Cancer. Journal of Biological Chemistry (2025)

Abstract 2539 Defining the Molecular Heterogeneity and Functional Impact of Pancreatic Cancer-Associated Kras Mutations. Journal of Biological Chemistry (2025)

Computational Structural Genomics and Clinical Evidence Suggest Bckdk Gain-Of-Function May Cause a Potentially Asymptomatic Maple Syrup Urine Disease Phenotype.. Epigenomics (2025)

proteome researchgenomicsdisease gene identificationcomputational structural genomicsmolecular diagnosticsclinical proteomicssystems biologyhuman geneticsmedical geneticsbioinformaticsgenetics

Genomic Features of the Methylosome Protein Mep50 and Its Implication in Hormone Signaling and Cancer. Endocrine Connections (2025)

Mutational Landscapes of Hnf Mody Gene Products Display a Wide Distribution With Functional Implications. Endocrine Connections (2025)

Computational Structural Genomics and Clinical Evidence Suggest Bckdk Gain‐of‐Function May Cause a Potentially Asymptomatic Maple Syrup Urine Disease Phenotype. JIMD Reports (2024)

Emily SinghYoung‐In ChiJessica KopeskyMichael ZimmermanRaul UrrutiaDonald BaselJessica Scott Schwoerer

computational biologygenomicsstructural genomicscomputational structural genomicscomputational genomicsbioinformaticsgenetics

Emergent Properties of the Lysine Methylome Reveal Regulatory Roles via Protein Interactions and Histone Mimicry. Epigenomics (2024)

Gareth PollinYoung-In ChiAngela J. MathisonMichael T. ZimmermannGwen LomberkRaul Urrutia

protein interactionshistone mimicryepigenomicsmolecular biology

A Multi-Layered Computational Structural Genomics Approach Enhances Domain-Specific Interpretation of Kleefstra Syndrome Variants in Ehmt1. Computational and Structural Biotechnology Journal (2023)

A Multi-Layered Computational Structural Genomics Approach Enhances Domain-Specific Interpretation of Kleefstra Syndrome Variants in Ehmt1. bioRxiv (Cold Spring Harbor Laboratory) (2023)

Young-In ChiSalomão D. JorgeDavin R. JensenBrian C. SmithBrian F. VolkmanAngela J. MathisonGwen LomberkMichael T. ZimmermannRaul Urrutia

kleefstra syndrome variantsdomain-specific interpretationgenomicsstructural genomicsmolecular biologycomputational genomics

Deep Computational Phenotyping of Genomic Variants Impacting the Set Domain of Kmt2C Reveal Molecular Mechanisms for Their Dysfunction. Frontiers in Genetics (2023)

Salomão Dória JorgeYoung-In ChiJose Lizarraga MazabaNeshatul HaqueJessica WagenknechtBrian C. SmithBrian F. VolkmanAngela J. MathisonGwen LomberkMichael T. ZimmermannRaul Urrutia

deep computational phenotypinggenomic mechanismsset domaingenomicsgenomic variantsgenetics

1
2
3
4
5
9
10 / page

Similar Faculty Members

Simone Sidoli

Institution

Albert Einstein College of Medicine

protein mass spectrometry

proteome research

Gwen Lomberk

Institution

Medical College of Wisconsin

epigenetics

cancer genomics

Stephen K. Burley

Institution

Rutgers University–New Brunswick

protein structure

clinical proteomics

Janknecht, Ralf

Institution

University of Oklahoma

molecular biology

cell biology

Liang Tong

Institution

Columbia University

molecular biology

structural biology

Raul A. Urrutia, MD

Institution

Medical College of Wisconsin

epigenetics

histone deacetylase

Frank Mccormick

Institution

University of California, San Francisco

signaling pathway

cancer cell

Pradeep K. Dudeja

Institution

University of Illinois Chicago

gastroenterology

cell biology

Stephen K. Burley

Institution

Rutgers University–Newark

protein structure

clinical proteomics

Surinder Batra

Institution

University of Nebraska Medical Center

cancer letter

antibody engineering

Similar Faculty Members

Simone Sidoli

Institution

Albert Einstein College of Medicine

protein mass spectrometry

proteome research

Gwen Lomberk

Institution

Medical College of Wisconsin

epigenetics

cancer genomics

Stephen K. Burley

Institution

Rutgers University–New Brunswick

protein structure

clinical proteomics

Janknecht, Ralf

Institution

University of Oklahoma

molecular biology

cell biology

Liang Tong

Institution

Columbia University

molecular biology

structural biology

Raul A. Urrutia, MD

Institution

Medical College of Wisconsin

epigenetics

histone deacetylase

Frank Mccormick

Institution

University of California, San Francisco

signaling pathway

cancer cell

Pradeep K. Dudeja

Institution

University of Illinois Chicago

gastroenterology

cell biology

Stephen K. Burley

Institution

Rutgers University–Newark

protein structure

clinical proteomics

Surinder Batra

Institution

University of Nebraska Medical Center

cancer letter

antibody engineering