Faculty

Institution

Unit

Venue

Yoon-Kwang Lee

Northeast Ohio Medical University

Affiliations

Department Of Biomedical Sciences

Department Of Cardiovascular Medicine

Northeast Ohio Medical University

School Of Medicine

NoneYoon-kwang Lee is currently serving as a Biomedical Sciences faculty at Northeast Ohio Medical University.

Honors

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Experiences

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Education

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Yoon-Kwang Lee

Northeast Ohio Medical University

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pharmacology membrane biology liver physiology hepatology endocrinology molecular biology physiology biochemistry gene expression vascular biology mammalian biology metabolism medicinal research protein science biological chemistry liver disease enzymes receptors lipoprotein metabolism clinical lipidology digestive diseases renal function lipid science medicinal chemistry molecular physiology redox biology receptor (biochemistry) transcription regulation knockout mice structural molecular biology cardiovascular research metabolic syndrome clinical biochemistry enzyme inhibition cell metabolism gene regulation metabolic regulation fatty liver disease molecular regulation secondary metabolism lipid disorders receptor tyrosine kinases functional modification pharmaceutical sciences lipid chemistry small heterodimer partner tissue development embryonic development cell regulation cellular biology human sciences micro-level evidence science studies medical genetics host genetics biological inorganic chemistry antibiotic resistance host response host specificity hepatotoxicity gene structure negative feedback regulation bile acid production redundant pathways differential transactivation nuclear-receptor-dependent phosphatidylcholine pathway antidiabetic effects hepatic lipid homeostasis mild obesity japanese subjects cholesterol absorption cholesterol transport bile acid composition differential regulation gene promoter dual mechanisms

Notable Scholarly Works

Notable Federal Grants

Collaborators

The Cyp4/20-Hete/Gpr75 Axis in the Progression of Metabolic Dysfunction-Associated Steatosis Liver Disease (Masld) to Chronic Liver Disease. Frontiers in Physiology (2025)

Effect of Aerobic Exercise and Particulate Matter Exposure Duration on the Diversity of Gut Microbiota. Animal Cells and Systems (2024)

Saba ImdadJin-Hee KimByunghun SoJunho JangJinhan ParkWonchung LimYoon-Kwang LeeWoo Shik ShinTrae HillyerChounghun Kang

animal scienceaerobiologyaerobic exerciseenvironmental scienceavian biologygut microbiotamicrobial diversitymammalian biologymicrobiome

The Fatty Acid Omega Hydroxylase Genes (Cyp4 Family) in the Progression of Metabolic Dysfunction-Associated Steatotic Liver Disease (Masld): An Rna Sequence Database Analysis and Review. Biochemical Pharmacology (2024)

Charles LeahyNicholas OsborneLeticia ShirotaPaula RoteYoon-Kwang LeeByoung-Joon SongLiya YinYanqiao ZhangVictor GarciaJames P Hardwick

fatty liver diseaseepidemiologymetabolismenzymesclinical biochemistrymolecular metabolismliver physiologyclinical lipidologyliver diseasebioinformatics databaselipoprotein metabolismhepatologybiochemistrycell metabolismpharmacologytranscriptomics technologygene expressionbioinformatics

Deletion of Hepatic Small Heterodimer Partner Ameliorates Development of Nonalcoholic Steatohepatitis in Mice. Journal of Lipid Research (2023)

Yoon-Kwang LeeJung Eun ParkMikang LeeRyan MifflinYang XuRobert NovakYanqiao ZhangJames P. Hardwick

lipidsepidemiologylipid chemistryliver physiologydermatologygeneticsvascular biologyclinical lipidologyhematologylipid sciencedigestive diseasesnonalcoholic steatohepatitisendocrinologylipid disordersliver diseaseprotein sciencelipoprotein metabolismhepatologymembrane biology

Identification of Bile Acid-Coa: Amino Acid N-Acyltransferase as the Hepatic N-Acyl Taurine Synthase for Polyunsaturated Fatty Acids. Journal of Lipid Research (2023)

Samuel A.J. TrammellLuke F. GamonKamil GotfrydKatja Thorøe MichlerBandar D. AlrehailiIben RixFilip K. KnopPontus GourdonYoon-Kwang LeeMichael J. DaviesMatthew P. GillumTrisha J. Grevengoed

lipidslipid chemistryliver physiologylipid analysispharmacologypolyunsaturated fatty acidsclinical lipidologyenzymeslipid scienceprotein synthesisbiochemistrymedicinal chemistrycardiovascular researchprotein sciencelipoprotein metabolismnutritional biochemistryhepatologybiomedical engineeringmembrane biology

Microbial Products Linked to Steatohepatitis Are Reduced by Deletion of Nuclear Hormone Receptor Shp in Mice. Journal of Lipid Research (2023)

Ryan MifflinJung Eun ParkMikang LeePrasant Kumar JenaYu-Jui Yvonne WanHazel A. BartonMirjavid AghayevTakhar KasumovLi LinXinwen WangRobert NovakFeng LiHe HuangLeah P. ShriverYoon-Kwang Lee

clinical microbiologyimmunologymicrobiologyveterinary medicinemicrobial products

Bile Acid Conjugation Deficiency Causes Hypercholanemia, Hyperphagia, Islet Dysfunction, and Gut Dysbiosis in Mice. Hepatology Communications (2022)

Bandar D. AlrehailiMikang LeeShogo TakahashiRobert NovakBipin RimalShannon BoehmeSamuel A. J. TrammellTrisha J. GrevengoedDevendra KumarYazen AlnoutiKatya ChitiXinwen WangAndrew D. PattersonJohn Y. L. ChiangFrank J. GonzalezYoon‐Kwang Lee

vascular biologyrenal functionnephrologyliver physiologyislet dysfunctiongastroenterologyimmunologyhepatologyhematologydigestive diseasespharmacologyrenal pathophysiologyendocrinologygut dysbiosishealth scienceshost-microbe interactions

Cyp4V2 Fatty Acid Omega Hydroxylase, a Druggable Target for the Treatment of Metabolic Associated Fatty Liver Disease (Mafld). Biochemical Pharmacology (2021)

Nicholas OsborneCharles LeahyYoon-Kwang LeePaula RoteByoung-Joon SongJames P. Hardwick

fatty liver diseasemetabolismenzymesliver diseasedrug targetingdrug targetsbiological targetsbiochemistrymedicinepharmacologydrug metabolismdrug discoverytherapeutic targetsdruggable target

The Mitochondrial Mitoneet Ligand Nl-1 is Protective in a Murine Model of Transient Cerebral Ischemic Stroke. Pharmaceutical Research (2021)

Pushkar SaralkarAlexander MdzinarishviliTasneem A ArsiwalaYoon-Kwang LeePatrick G. SullivanMark V. PintiJohn M. HollanderEric E. KelleyXuefang RenHeng HuJames SimpkinsCandice BrownLori E. HazlehurstJason D. HuberWerner J. Geldenhuys

neuropharmacologyneuroscienceneuroradiologypharmacologyneuroprotectionmurine modeldrug discoverypharmaceutical sciencesmedicinal researchstrokepharmaceutical researchneurologymolecular medicinepharmaceuticsexperimental medicinemitochondrial functionclinical researchpharmacological researchpharmaceutical practice

Mice With Bile Acid‐Coa: Amino Acid N‐Acyltransferase Deletion Are Protected From Obesity. The FASEB Journal (2020)

Bandar D. AlrehailiMikang LeeShogo TakahashiFrank J. GonzalezYoon-Kwang Lee

knockout micepharmacologymolecular biologymammalian biologyobesitygenetics

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Yoon-Kwang Lee

Northeast Ohio Medical University

Affiliations

Department Of Biomedical Sciences

Department Of Cardiovascular Medicine

Northeast Ohio Medical University

School Of Medicine

NoneYoon-kwang Lee is currently serving as a Biomedical Sciences faculty at Northeast Ohio Medical University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Yoon-Kwang Lee

Northeast Ohio Medical University

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

The Cyp4/20-Hete/Gpr75 Axis in the Progression of Metabolic Dysfunction-Associated Steatosis Liver Disease (Masld) to Chronic Liver Disease. Frontiers in Physiology (2025)

Effect of Aerobic Exercise and Particulate Matter Exposure Duration on the Diversity of Gut Microbiota. Animal Cells and Systems (2024)

Saba ImdadJin-Hee KimByunghun SoJunho JangJinhan ParkWonchung LimYoon-Kwang LeeWoo Shik ShinTrae HillyerChounghun Kang

animal scienceaerobiologyaerobic exerciseenvironmental scienceavian biologygut microbiotamicrobial diversitymammalian biologymicrobiome

Charles LeahyNicholas OsborneLeticia ShirotaPaula RoteYoon-Kwang LeeByoung-Joon SongLiya YinYanqiao ZhangVictor GarciaJames P Hardwick

Deletion of Hepatic Small Heterodimer Partner Ameliorates Development of Nonalcoholic Steatohepatitis in Mice. Journal of Lipid Research (2023)

Yoon-Kwang LeeJung Eun ParkMikang LeeRyan MifflinYang XuRobert NovakYanqiao ZhangJames P. Hardwick

Identification of Bile Acid-Coa: Amino Acid N-Acyltransferase as the Hepatic N-Acyl Taurine Synthase for Polyunsaturated Fatty Acids. Journal of Lipid Research (2023)

Samuel A.J. TrammellLuke F. GamonKamil GotfrydKatja Thorøe MichlerBandar D. AlrehailiIben RixFilip K. KnopPontus GourdonYoon-Kwang LeeMichael J. DaviesMatthew P. GillumTrisha J. Grevengoed

Microbial Products Linked to Steatohepatitis Are Reduced by Deletion of Nuclear Hormone Receptor Shp in Mice. Journal of Lipid Research (2023)

Ryan MifflinJung Eun ParkMikang LeePrasant Kumar JenaYu-Jui Yvonne WanHazel A. BartonMirjavid AghayevTakhar KasumovLi LinXinwen WangRobert NovakFeng LiHe HuangLeah P. ShriverYoon-Kwang Lee

clinical microbiologyimmunologymicrobiologyveterinary medicinemicrobial products

Bile Acid Conjugation Deficiency Causes Hypercholanemia, Hyperphagia, Islet Dysfunction, and Gut Dysbiosis in Mice. Hepatology Communications (2022)

Cyp4V2 Fatty Acid Omega Hydroxylase, a Druggable Target for the Treatment of Metabolic Associated Fatty Liver Disease (Mafld). Biochemical Pharmacology (2021)

Nicholas OsborneCharles LeahyYoon-Kwang LeePaula RoteByoung-Joon SongJames P. Hardwick

fatty liver diseasemetabolismenzymesliver diseasedrug targetingdrug targetsbiological targetsbiochemistrymedicinepharmacologydrug metabolismdrug discoverytherapeutic targetsdruggable target

The Mitochondrial Mitoneet Ligand Nl-1 is Protective in a Murine Model of Transient Cerebral Ischemic Stroke. Pharmaceutical Research (2021)

Mice With Bile Acid‐Coa: Amino Acid N‐Acyltransferase Deletion Are Protected From Obesity. The FASEB Journal (2020)

Bandar D. AlrehailiMikang LeeShogo TakahashiFrank J. GonzalezYoon-Kwang Lee

knockout micepharmacologymolecular biologymammalian biologyobesitygenetics

1
2
3
4
5
10 / page