Yi-Qian Nancy You, MD, MHSc, FACS

Yi-Qian Nancy You, MD, MHSc, FACS, is a Professor in the Department of Surgical Oncology at The University of Texas MD Anderson Cancer Center. A board-certified surgical oncologist, she specializes in the surgical management of colorectal cancer and gastrointestinal malignancies. Her research focuses on the molecular and mutational landscape of early-onset colorectal cancer, the clinical utility of circulating tumor DNA (ctDNA) in immunotherapy response, and the adoption of robotic minimally invasive surgery. Her recent work includes landmark publications on the co-mutational landscape of early-onset disease and long-term efficacy of pembrolizumab in dMMR/MSI-H tumors. She also leads national initiatives to establish dedicated early-onset colorectal cancer programs and standardize care for hereditary polyposis syndromes.