Faculty

Institution

Unit

Venue

Yang, Liuqing

The University of Texas MD Anderson Cancer Center

Affiliations

Center For Rna Interference And Non-Coding Rna

Department Of Epigenetics And Molecular Carcinogenesis

Liuqing Yang is a Senior Professor at The University of Texas MD Anderson Cancer Center. Her research integrates cell, molecular, and tumor biology to investigate oncogenic signaling, gene expression regulation, and anti-tumor immunity. Recent breakthroughs include demonstrating that sickle cell disease induces chromatin introversion and ferroptosis in CD8+ T cells to suppress anti-tumor immunity (Immunity, 2025), and elucidating FGFR3-induced Y158 PARP1 phosphorylation that promotes PARP inhibitor resistance via BRG1/MRE11-mediated DNA repair in breast cancer models (Journal of Clinical Investigation, 2025). Her work also spans snoRNA pharmacogenomics across human cancers, PVT1-mediated immune exclusion in pancreatic cancer, and lncRNA-IL-15 crosstalk in NK cell rejuvenation. She has secured major funding, including a $1.2 million award for cotargeting lncRNA-PIP3 interactions and AKT/PI3K signaling in triple-negative breast cancer.

Honors

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Experiences

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Yang, Liuqing

The University of Texas MD Anderson Cancer Center

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molecular biology cell biology tumor biology gene expression cancer research cancer biology genetics long non-coding rna oncogenes cancer cells medicinal research rna biology non-coding rna molecular cell biology pharmacology oncology molecular cancer breast cancer cancer genetics genome biology cell signaling nucleic acids cell research tumor suppressors cancer immunotherapy membrane biology molecular physiology leukemia molecular regulation cancer genomics protein science cellular physiology cellular biology gene regulation cellular immune responses cancer care clinical investigation enzyme inhibition cancer discovery cell regulation signaling pathways pancreatic cancer protein phosphorylation transcription regulation cancer growth gene function cancer risk anti-cancer agents chromosome biology drug targeting clinical medicine breast oncology tumoral pathology tumor targeting cancer immunosurveillance triple-negative breast cancer in vivo systems molecular immunology oncogenic agent innate immune system cytokines lncrna-dependent mechanisms link-a lncrna chemokine signals intrinsic tumor suppression oncogenic lncrna bone metastasis hippo-yap pathway tumoral ferroptosis innate immunity hypoxia-targeted therapy hypoxia-associated molecular features pan-cancer analysis human cancer small nucleolar rnas clinical relevance

Notable Scholarly Works

Notable Federal Grants

Collaborators

Expression of Concern for Jak2-Binding Long Noncoding Rna Promotes Breast Cancer Brain Metastasis. Journal of Clinical Investigation (2025)

metastasiscancer biologycell biologycancer cellsmolecular cell biologyoncogenesbrain tumor researchnon-coding rnamolecular biologycarcinogenesisbreast cancerlong non-coding rna

Fgfr3-Induced Y158 Parp1 Phosphorylation Promotes Parp Inhibitor Resistance via Brg1/Mre11-Mediated Dna Repair in Breast Cancer Models. Journal of Clinical Investigation (2025)

brg1/mre11-mediated dna repaircancer biologytumor suppressorscell biologycancer cellsbreast cancer modelscancer geneticsparp inhibitor resistancetherapeutic targetsdna repairmolecular biologycancer discoverybreast cancercell death

Sickle Cell Disease Induces Chromatin Introversion and Ferroptosis in Cd8+ T Cells to Suppress Anti-Tumor Immunity. Immunity (2025)

immune responsescellular therapycd8+ t cellscell biologyleukemiaadaptive immune systemimmunologyimmunity (medicine)sickle cell diseasechromatin introversioncell deathcellular immune responses

Abstract 3853: T Cell Ferroptosis Attenuates Antitumor Immune Responses in Sickle Cell Disease. Cancer Research (2024)

immune responsest-regulatory cellcell biologyabstract 3853immunotherapyimmunologysickle cell diseasecell researcht cell ferroptosiscell deathcellular immune responses

The Pharmacogenomic and Immune Landscape of Snornas in Human Cancers. Cancer Letters (2024)

Runhao WangChengxuan ChenYuan LiuMei LuoJingwen YangYamei ChenLifei MaLiuqing YangChunru LinLixia DiaoLeng Han

cancer lettercancer genomicscancer immunotherapytumor biologycancer researchoncologycancer biologyimmune landscapecancer cellstumoral pathologycancer immunosurveillanceimmunologyhuman cancerstumor microenvironmenttumor heterogeneity

Molecular Mechanisms of Snorna-Il-15 Crosstalk in Adipocyte Lipolysis and Nk Cell Rejuvenation. Cell Metabolism (2023)

Yaohua ZhangZilong ZhaoLisa A. HuangYuan LiuJun YaoChengcao SunYajuan LiZhao ZhangYouqiong YeFei YuanTina K. NguyenNikhil Reddy GarlapatiAndrew WuSergey D. EgranovAbigail S. CaudleAysegul A. SahinBora LimLaura BerettaGeorge A. CalinDihua YuMien-Chie HungMichael A. CurranKatayoun RezvaniBoyi GanZhi TanLeng HanChunru LinLiuqing Yang

gene expressionsocial science researchmolecular mechanismsadipocyte lipolysisregenerative medicinepharmacologymembrane biologysocial sciencesmolecular biologynk cell rejuvenationmolecular physiology

Plumbing Mysterious Rnas in “Dark Genome” for the Conquest of Human Diseases. Molecular Therapy (2023)

geneticsmysterious rnasnon-coding rnanucleic acidshuman diseasesgenomicstranscriptomerna biologygenome biologymolecular biologyvirus research

Tumor-Associated Nonmyelinating Schwann Cell–Expressed Pvt1 Promotes Pancreatic Cancer Kynurenine Pathway and Tumor Immune Exclusion. Science Advances (2023)

Chengcao SunYouqiong YeZhi TanYuan LiuYajuan LiWei HuKe LiangSergey D. EgranovLisa Angela HuangZhao ZhangYaohua ZhangJun YaoTina K. NguyenZilong ZhaoAndrew WuJeffrey R. MarksAbigail S. CaudleAysegul A. SahinJianjun GaoSeth T. GammonDavid Piwnica-WormsJian HuPaul J. ChiaoDihua YuMien-Chie HungMichael A. CurranGeorge A. CalinHaoqiang YingLeng HanChunru LinLiuqing Yang

tumor biologycancer immunotherapycancer biologytumor suppressorsdermatologycell biologypancreatic cancertumor immune exclusioncell-matrix interactionsimmunologygene expressionscience advancemedicinal research

Abstract 1792: Fgfr3 Mediated Parp1 Tyrosine 158 Phosphorylation Promotes Parp Inhibitor Resistance. Cancer Research (2022)

MeiKuang ChenYuan GaoWeiya XiaYu-Han WangJennifer K. LittonYu-Yi ChuFunda Meric-BernstamHelen Piwnica-WormsBanu ArunJordi Rodon AhnertYongkun WeiWei-Chao ChangHung-Ling WangCoya TapiaConstance T. AlbarracinShao-Chun WangYing-Nai WangGabriel N. HortobagyiChunru LinLiuqing YangDihua YuMien-Chie Hung

parpi resistancetumor biologycancer growthradiation oncologycancer biologyparp1 tyrosine 158cell biologycancer cellsoncogenestyrosine 158cancer geneticstherapeutic targetsbreast cancermedicinal research

Ephrin Receptor A10 Monoclonal Antibodies and the Derived Chimeric Antigen Receptor T Cells Exert an Antitumor Response in Mouse Models of Triple-Negative Breast Cancer. Journal of Biological Chemistry (2022)

Jong-Ho ChaLi-Chuan ChanYing-Nai WangYu-Yi ChuChie-Hong WangHeng-Huan LeeWeiya XiaWoei-Cherng ShyuShih-Ping LiuJun YaoChiung-Wen ChangFan-Ru ChengJielin LiuSeung-Oe LimJennifer L. HsuWen-Hao YangGabriel N. HortobagyiChunru LinLiuqing YangDihua YuLong-Bin JengMien-Chie Hung

receptorscancer immunotherapyephrin receptorcell biologyleukemiabreast oncologycancer immunosurveillancepharmacologytumor biologycellular therapyantitumor responseimmunotherapybiological chemistryclinical immunologyclinical biochemistryanti-cancer agentsmonoclonal antibodiesmouse modelsimmunologytumor targetingbreast cancermedicinal researchtriple-negative breast cancer

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Yang, Liuqing

The University of Texas MD Anderson Cancer Center

Affiliations

Center For Rna Interference And Non-Coding Rna

Department Of Epigenetics And Molecular Carcinogenesis

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Yang, Liuqing

The University of Texas MD Anderson Cancer Center

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Expression of Concern for Jak2-Binding Long Noncoding Rna Promotes Breast Cancer Brain Metastasis. Journal of Clinical Investigation (2025)

metastasiscancer biologycell biologycancer cellsmolecular cell biologyoncogenesbrain tumor researchnon-coding rnamolecular biologycarcinogenesisbreast cancerlong non-coding rna

Fgfr3-Induced Y158 Parp1 Phosphorylation Promotes Parp Inhibitor Resistance via Brg1/Mre11-Mediated Dna Repair in Breast Cancer Models. Journal of Clinical Investigation (2025)

Sickle Cell Disease Induces Chromatin Introversion and Ferroptosis in Cd8+ T Cells to Suppress Anti-Tumor Immunity. Immunity (2025)

immune responsescellular therapycd8+ t cellscell biologyleukemiaadaptive immune systemimmunologyimmunity (medicine)sickle cell diseasechromatin introversioncell deathcellular immune responses

Abstract 3853: T Cell Ferroptosis Attenuates Antitumor Immune Responses in Sickle Cell Disease. Cancer Research (2024)

immune responsest-regulatory cellcell biologyabstract 3853immunotherapyimmunologysickle cell diseasecell researcht cell ferroptosiscell deathcellular immune responses

The Pharmacogenomic and Immune Landscape of Snornas in Human Cancers. Cancer Letters (2024)

Runhao WangChengxuan ChenYuan LiuMei LuoJingwen YangYamei ChenLifei MaLiuqing YangChunru LinLixia DiaoLeng Han

Molecular Mechanisms of Snorna-Il-15 Crosstalk in Adipocyte Lipolysis and Nk Cell Rejuvenation. Cell Metabolism (2023)

gene expressionsocial science researchmolecular mechanismsadipocyte lipolysisregenerative medicinepharmacologymembrane biologysocial sciencesmolecular biologynk cell rejuvenationmolecular physiology

Plumbing Mysterious Rnas in “Dark Genome” for the Conquest of Human Diseases. Molecular Therapy (2023)

geneticsmysterious rnasnon-coding rnanucleic acidshuman diseasesgenomicstranscriptomerna biologygenome biologymolecular biologyvirus research

Tumor-Associated Nonmyelinating Schwann Cell–Expressed Pvt1 Promotes Pancreatic Cancer Kynurenine Pathway and Tumor Immune Exclusion. Science Advances (2023)

Abstract 1792: Fgfr3 Mediated Parp1 Tyrosine 158 Phosphorylation Promotes Parp Inhibitor Resistance. Cancer Research (2022)

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