Faculty

Institution

Unit

Venue

Xue-Jun Li

Professor

University of Illinois Chicago

Affiliations

College of Engineering

Biomedical Engineering

Xue-jun Li is currently serving as a Biomedical Engineering Professor at University of Illinois Chicago.

Honors

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Experiences

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Education

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Xue-Jun Li

University of Illinois Chicago

Professor

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neuroscience cell biology stem cell research neurology stem cells developmental neurobiology molecular neurodegeneration spinal cord neural stem cells genetics neurodegenerative diseases neurophysiology embryonic stem cells neurogenetics cellular neurobiology neuropathology cerebral blood flow induced pluripotent stem cells melatonin neuroprotection molecular neurobiology cerebral organoids hereditary spastic paraplegia neuroanatomy neuropharmacology free radical biology mitochondrial function neurochemistry hereditary spastic paraplegias neural science antioxidants stroke rehabilitation nanotoxicology neuroinflammation cerebral vascular regulation spinal muscular atrophy neuroradiology protein science vascular biology neuroscience of aging brain science clinical neuroscience spinal disorders human embryonic development dopamine neurological disorders experimental medicine avian biology histopathology developmental science genome biology metal toxicity disease mechanisms disease pathophysiology disease physiology renal function embryonic development medical genetics lipid disorders genetic basis neurotransmission cerebrovascular disease neurovascular diseases region-specific neurons forebrain glutamatergic neurons metal debris local toxicity hip prostheses novel modality abnormal mitochondrial transport human models early pathological changes side population properties cerebral ischemia-reperfusion host brain brain repair motor neurons neuroregeneration spinal cord injury

Notable Scholarly Works

Notable Federal Grants

Collaborators

Cocrmo Nanoparticle Induces Neurotoxicity Mediated via Mitochondrial Dysfunction: A Study Model for Implant Derived Nanoparticle Effects. Nanotoxicology (2024)

Priyadarshini VijayakumarYongchao MouXuejun LiJahnavi AnilNeeraja ReviKai-yuan ChengMathew T. MathewDivya Bijukumar

nanoparticlesmitochondrial dysfunctionstudy modelneurosciencenanotoxicologynanoparticle researchnanoparticle effects

Targeting Cholesterol Trafficking to Mitigate Axonal Degeneration in Hereditary Spastic Paraplegia. Neural Regeneration Research (2024)

Zhenyu ChenXue-Jun Li

inflammationneurodegenerative diseaseshereditary spastic paraplegiaheme traffickingneuroprotectionaxonal degenerationneuroscienceregenerative medicinecholesterol traffickingneurologypathology

Chenodeoxycholic Acid Rescues Axonal Degeneration in Induced Pluripotent Stem Cell-Derived Neurons From Spastic Paraplegia Type 5 and Cerebrotendinous Xanthomatosis Patients. Orphanet Journal of Rare Diseases (2023)

Yongchao MouGhata NandiSukhada MukteEric ChaiZhenyu ChenJorgen E. NielsenTroels T. NielsenChiara CriscuoloCraig BlackstoneMatthew J. FraidakisXue-Jun Li

geneticsneurodegenerative diseasesneuroscienceregenerative medicineneurogeneticsneurodevelopmental disordersneurology

Liver-X-Receptor Agonists Rescue Axonal Degeneration in Spg11-Deficient Neurons via Regulating Cholesterol Trafficking. Neurobiology of Disease (2023)

Eric ChaiZhenyu ChenYongchao MouGitika ThakurWeihai ZhanXue-Jun Li

cellular neurobiologyclinical neuroscienceaxonal degenerationneurosciencemolecular neurobiologyneuroradiologyliver physiologycholesterol traffickingmolecular neurodegenerationneurologyliver-x-receptor agonistsneurophysiologyneural sciencegeneticsneuropharmacologymolecular neurosciencecentral nervous systemneuroanatomyfunctional regulation

Inhibiting Mitochondrial Fission Rescues Degeneration in Hereditary Spastic Paraplegia Neurons. Brain (2021)

Zhenyu ChenEric ChaiYongchao MouRicardo H RodaCraig BlackstoneXue-Jun Li

geneticsbrain scienceneuroscienceneurogeneticsneurology

Mfn2 Deficiency Impairs Mitochondrial Transport and Downregulates Motor Protein Expression in Human Spinal Motor Neurons. Frontiers in Molecular Neuroscience (2021)

Yongchao MouJoshua DeinZhenyu ChenMrunali JagdaleXue-Jun Li

systems neurosciencegeneticsneuropathologymitochondrial functionneurochemistrycellular neurobiologymolecular neuroscienceneurosciencemolecular neurobiologyneurotransmissionsignal transductionneurologymotor control

Modeling Hereditary Spastic Paraplegias Using Induced Pluripotent Stem Cells. Elsevier eBooks (2021)

Yongchao MouZhenyu ChenXue-Jun Li

geneticsneuroscienceregenerative medicineneurologyhereditary spastic paraplegiasbiomedical modeling

Monitoring Axonal Degeneration in Human Pluripotent Stem Cell Models of Hereditary Spastic Paraplegias. Methods in molecular biology (2021)

developmental biologystem cell researchstem-cell therapystem cellsspinal cord injurycell biologyaxonal degenerationspinal corddegenerative diseaseneural stem cellshereditary spastic paraplegias

Non-Cell Autonomous Role of Astrocytes in Axonal Degeneration of Cortical Projection Neurons in Hereditary Spastic Paraplegias. Neural Regeneration Research (2021)

Xue-Jun Li

cortical projection neuronsneuroregenerationaxonal degenerationneurosciencehereditary spastic paraplegias

Stem Cell Models and Gene Targeting for Human Motor Neuron Diseases. Pharmaceuticals (2021)

Yashashree KarpeZhenyu ChenXue-Jun Li

pharmaceutical sciencesmedicinestem cell modelsneurosciencepharmacologygene therapy

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Xue-Jun Li

Professor

University of Illinois Chicago

Affiliations

College of Engineering

Biomedical Engineering

Xue-jun Li is currently serving as a Biomedical Engineering Professor at University of Illinois Chicago.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Xue-Jun Li

University of Illinois Chicago

Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Cocrmo Nanoparticle Induces Neurotoxicity Mediated via Mitochondrial Dysfunction: A Study Model for Implant Derived Nanoparticle Effects. Nanotoxicology (2024)

Priyadarshini VijayakumarYongchao MouXuejun LiJahnavi AnilNeeraja ReviKai-yuan ChengMathew T. MathewDivya Bijukumar

nanoparticlesmitochondrial dysfunctionstudy modelneurosciencenanotoxicologynanoparticle researchnanoparticle effects

Targeting Cholesterol Trafficking to Mitigate Axonal Degeneration in Hereditary Spastic Paraplegia. Neural Regeneration Research (2024)

Zhenyu ChenXue-Jun Li

inflammationneurodegenerative diseaseshereditary spastic paraplegiaheme traffickingneuroprotectionaxonal degenerationneuroscienceregenerative medicinecholesterol traffickingneurologypathology

Yongchao MouGhata NandiSukhada MukteEric ChaiZhenyu ChenJorgen E. NielsenTroels T. NielsenChiara CriscuoloCraig BlackstoneMatthew J. FraidakisXue-Jun Li

geneticsneurodegenerative diseasesneuroscienceregenerative medicineneurogeneticsneurodevelopmental disordersneurology

Liver-X-Receptor Agonists Rescue Axonal Degeneration in Spg11-Deficient Neurons via Regulating Cholesterol Trafficking. Neurobiology of Disease (2023)

Eric ChaiZhenyu ChenYongchao MouGitika ThakurWeihai ZhanXue-Jun Li

Inhibiting Mitochondrial Fission Rescues Degeneration in Hereditary Spastic Paraplegia Neurons. Brain (2021)

Zhenyu ChenEric ChaiYongchao MouRicardo H RodaCraig BlackstoneXue-Jun Li

geneticsbrain scienceneuroscienceneurogeneticsneurology

Mfn2 Deficiency Impairs Mitochondrial Transport and Downregulates Motor Protein Expression in Human Spinal Motor Neurons. Frontiers in Molecular Neuroscience (2021)

Yongchao MouJoshua DeinZhenyu ChenMrunali JagdaleXue-Jun Li

Modeling Hereditary Spastic Paraplegias Using Induced Pluripotent Stem Cells. Elsevier eBooks (2021)

Yongchao MouZhenyu ChenXue-Jun Li

geneticsneuroscienceregenerative medicineneurologyhereditary spastic paraplegiasbiomedical modeling

Monitoring Axonal Degeneration in Human Pluripotent Stem Cell Models of Hereditary Spastic Paraplegias. Methods in molecular biology (2021)

developmental biologystem cell researchstem-cell therapystem cellsspinal cord injurycell biologyaxonal degenerationspinal corddegenerative diseaseneural stem cellshereditary spastic paraplegias

Non-Cell Autonomous Role of Astrocytes in Axonal Degeneration of Cortical Projection Neurons in Hereditary Spastic Paraplegias. Neural Regeneration Research (2021)

Xue-Jun Li

cortical projection neuronsneuroregenerationaxonal degenerationneurosciencehereditary spastic paraplegias

Stem Cell Models and Gene Targeting for Human Motor Neuron Diseases. Pharmaceuticals (2021)

Yashashree KarpeZhenyu ChenXue-Jun Li

pharmaceutical sciencesmedicinestem cell modelsneurosciencepharmacologygene therapy

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Similar Faculty Members

Kiminobu Sugaya

Institution

University of Central Florida

stem cell

stem-cell therapy

Itzhak Fischer

Institution

Drexel University

cellular differentiation

stem cell

Chia-Yi Kuan

Institution

University of Virginia

neuroscience

neurology

Lorraine Iacovitti

Institution

Thomas Jefferson University

stem cell

abnormal development

Marius Wernig

Institution

Stanford University

neuroscience

cell biology

Joseph S. Beckman

Institution

Oregon State University

neurodegenerative disease

neurology

Scott T Brady

Institution

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neuroscience

huntington's disease

Martin Marsala

Institution

University of California, San Diego

stem cell

muscle spasticity

Jeffery Kocsis

Institution

Yale University

neural engineering

spinal cord

Paul R. Sanberg

Institution

University of South Florida

neuroscience

cell transplantation