Faculty

Institution

Unit

Venue

Xin Jie Chen

Upstate Medical University

Affiliations

Norton College of Medicine

Department Of Anesthesiology

Department Of Neuroscience And Physiology

Department Of Anesthesiology

Norton College Of Medicine

Upstate Medical University

NoneXin Jie Chen is currently serving as a Anesthesiology faculty at Upstate Medical University.

Honors

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Experiences

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Education

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Xin Jie Chen

Upstate Medical University

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molecular biology mitochondrial function biochemistry cell metabolism molecular and cellular biology molecular cell biology cell biology mitochondrial dynamics molecular metabolism molecular genetics yeast dna repair oxidative stress genetics cell and molecular biology nucleic acids redox biology dna replication molecular neurodegeneration metabolic pathways genome biology fungal genetics mitochondrial biogenesis enzymes protein science free radical biology biological chemistry cell death cellular enzymology mitochondrial protein import structural molecular biology biomolecular structure bioenergetics apoptosis molecular research fungal cell biology mitochondrial dna aging cell genome instability recombination dynamic degenerative disease genomic mechanisms gene structure phylogenomics chromosome biology reductive stress metabolic regulation molecular regulation protein misfolding retina ocular disease microbial genetics transcription regulation gene function gene regulation molecular pathways protein assembly nucleic acid chemistry structural bioinformatics biogerontology aging process reverse genetics mitochondrial genome cytosolic network mitochondrial dna maintenance mitochondrial nucleoids mitochondrial degeneration aging-related deletions homologous recombination mitochondrial stress yeast aconitase binds mitochondria-cytosol-nucleus crosstalk essential cellular function calcium-dependent carrier protein novel mitochondrial trigger proteostatic adaptations

Notable Scholarly Works

Notable Federal Grants

Collaborators

Mitochondrial Precursor Overaccumulation Stress. Annual Review of Biochemistry (2026)

mitochondrial functionmetabolismoxidative stressredox biologybiochemistryfree radical biologymitochondrial dynamicscell metabolismstress (biology)

Mitochondrial Protein Import Stress Causes Lysosomal Damage and Progressive Tissue Atrophy. EMBO Reports (2026)

lysosomal damagemitochondrial functionneurodegenerative diseasesmuscular dystrophiescell biologymolecular cell biologyprogressive tissue atrophyautophagymitochondrial dynamicsmolecular neurodegenerationmolecular biologycell metabolism

Mitochondrial Protein Import Stress Causes Lysosomal Damage and Progressive Tissue Atrophy. (2026)

mitochondrial functionneurodegenerative diseasesmuscular dystrophiescell biologymolecular cell biologyprogressive tissue atrophyautophagymitochondrial dynamicsmolecular neurodegenerationmolecular biologycell metabolism

Cellular Proteostasis During Mitochondrial Protein Import Clogging Requires the Mitochondrial F-Box Protein 1 and Dj-1 Homolog Hsp31 in Saccharomyces Cerevisiae. Genetics (2025)

mitochondrial functioncellular proteostasisdj-1 homolog hsp31molecular and cellular biologyyeastcell biologymolecular cell biologymitophagyautophagyproteomicscell and molecular biologymitochondrial protein importmolecular biologycell metabolismcellular biochemistry

Mitochondrial Protein Import Stress Augments α-Synuclein Aggregation and Neural Damage Independent of Bioenergetics. Research Square (2025)

mitochondrial functiondegenerative pathologyneurodegenerative diseasesmolecular neurosciencecell biologyparkinson's diseaseredox biologybiochemistrymolecular neurodegenerationmolecular biologycell metabolismneural damagecellular biochemistry

The Mitochondrial F-Box Protein 1 and Dj-1 Homolog Hsp31 Support Cellular Proteostasis During Mitochondrial Protein Import Clogging. bioRxiv (Cold Spring Harbor Laboratory) (2025)

mitochondrial functionmolecular and cellular biologycell biologymolecular cell biologymitochondrial dynamicsproteomicsmitochondrial protein importmolecular biologycellular biochemistry

Adenine Nucleotide Carrier Protein Dysfunction in Human Disease. IUBMB Life (2023)

molecular pathwayscarrier protein dysfunctionmolecular neurodegenerationdna repairmolecular biologydegenerative disease

Author Response: Mitochondrial Protein Import Clogging as a Mechanism of Disease. (2023)

mitochondrial functionmolecular and cellular biologymolecular cell biologyauthor responsedisease mechanismsautophagypathogenesismembrane proteinsbiochemistrymitochondrial protein importmolecular biologycell metabolism

Mitochondrial Protein Import Clogging as a Mechanism of Disease. eLife (2023)

Liam P CoyneXiaowen WangJiyao SongEbbing de JongKarin SchneiderPaul T MassaFrank A MiddletonThomas BeckerXin Jie Chen

molecular biologymitochondrial protein import

Abstract 11029: Bioenergetic Independent Stress Signaling in the Heart Due to Mitochondrial Protein Import Stress. Circulation (2022)

mitochondrial functionoxidative stressabstract 11029cell biologycell signalingredox biologyheart duephysiologysignal transductioncardiovascular researchmolecular biologycell metabolismmitochondrial biogenesis

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Xin Jie Chen

Upstate Medical University

Affiliations

Norton College of Medicine

Department Of Anesthesiology

Department Of Neuroscience And Physiology

Department Of Anesthesiology

Norton College Of Medicine

Upstate Medical University

NoneXin Jie Chen is currently serving as a Anesthesiology faculty at Upstate Medical University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Xin Jie Chen

Upstate Medical University

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Mitochondrial Precursor Overaccumulation Stress. Annual Review of Biochemistry (2026)

mitochondrial functionmetabolismoxidative stressredox biologybiochemistryfree radical biologymitochondrial dynamicscell metabolismstress (biology)

Mitochondrial Protein Import Stress Causes Lysosomal Damage and Progressive Tissue Atrophy. EMBO Reports (2026)

Mitochondrial Protein Import Stress Causes Lysosomal Damage and Progressive Tissue Atrophy. (2026)

Cellular Proteostasis During Mitochondrial Protein Import Clogging Requires the Mitochondrial F-Box Protein 1 and Dj-1 Homolog Hsp31 in Saccharomyces Cerevisiae. Genetics (2025)

Mitochondrial Protein Import Stress Augments α-Synuclein Aggregation and Neural Damage Independent of Bioenergetics. Research Square (2025)

The Mitochondrial F-Box Protein 1 and Dj-1 Homolog Hsp31 Support Cellular Proteostasis During Mitochondrial Protein Import Clogging. bioRxiv (Cold Spring Harbor Laboratory) (2025)

mitochondrial functionmolecular and cellular biologycell biologymolecular cell biologymitochondrial dynamicsproteomicsmitochondrial protein importmolecular biologycellular biochemistry

Adenine Nucleotide Carrier Protein Dysfunction in Human Disease. IUBMB Life (2023)

molecular pathwayscarrier protein dysfunctionmolecular neurodegenerationdna repairmolecular biologydegenerative disease

Author Response: Mitochondrial Protein Import Clogging as a Mechanism of Disease. (2023)

Mitochondrial Protein Import Clogging as a Mechanism of Disease. eLife (2023)

Liam P CoyneXiaowen WangJiyao SongEbbing de JongKarin SchneiderPaul T MassaFrank A MiddletonThomas BeckerXin Jie Chen

molecular biologymitochondrial protein import

Abstract 11029: Bioenergetic Independent Stress Signaling in the Heart Due to Mitochondrial Protein Import Stress. Circulation (2022)

1
2
3
4
5
6
10 / page