Faculty

Institution

Unit

Venue

Xiaoping Du, MD, PhD

Professor

University of Illinois Chicago

Affiliations

College of Medicine of Chicago

Pharmacology and Regenerative Medicine

Xiaoping Du, Md, Phd is currently serving as a College Of Medicine Of Chicago Professor at University of Illinois Chicago.

Honors

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Experiences

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Education

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Xiaoping Du, MD, PhD

University of Illinois Chicago

Professor

You can click a keyword to filter the displayed items

cell biology hematology blood platelet vascular biology thrombosis cell signaling hemostasis immunology signal transduction platelet antagonist receptors cellular physiology molecular biology inflammation molecular cell biology molecular physiology cardiology cell-matrix interactions membrane biology cardiovascular research biochemistry medicinal research cellular biochemistry platelet activation biological chemistry hepatology protein science liver physiology experimental medicine angiology blood cells circulatory physiology protein secretion intracellular trafficking cell adhesion g protein-coupled receptor outside-in signaling protein function signaling pathways receptor tyrosine kinases molecular regulation coagulopathy cell migration platelet secretion cgmp-dependent protein kinase cellular biology protein phosphorylation blood flow cell trafficking angiogenesis endothelial dysfunction cytoplasmic domain cell research cell death applied physiology cytokines cerebrovascular disease biomolecular interactions vascular disease cardiovascular physiology critical role receptor (biochemistry) inhibitory activity integrative biology protein expression pharmaceutical nanotechnology platelet adhesion conformational changes long range propagation calpain cleavage platelet glycoprotein ibα platelet glycoprotein glycoprotein ib-ix lim kinase-1 platelet aggregation integrin-mediated cell adhesion

Notable Scholarly Works

Notable Federal Grants

Collaborators

Platelet Factor 4 (Pf4) Regulates Hematopoietic Stem Cell Aging. Blood (2025)

aging cellhematologystem cell researchplatelet factor 4haematopoiesisstem cellscell biologythrombopoiesisstem cell mobilizationblood platelet

Tapping Into the Natural Pz-Independent Anticoagulant Function of Zpi to Inhibit Thrombosis With Minimal Effect on Hemostasis. Arteriosclerosis Thrombosis and Vascular Biology (2025)

hematologyanticoagulantsmedicinehemostasisthrombosisimmunologypharmacologyvascular biologyinhibit thrombosisminimal effectclinical researchpharmacotherapy

Abstract 2098: A Novel Mechanism of Focal Adhesion Kinase Activation by Integrins and Its Role in Outside-in Signaling in Platelets. Arteriosclerosis Thrombosis and Vascular Biology (2024)

receptorsplatelet antagonistnovel mechanismoutside-in signalingcell biologycell signalingcell-matrix interactionsimmunologyextracellular matrixvascular biologymatrix biologysignal transductionabstract 2098cell adhesionthrombosiscellular physiologyblood platelet

Integrated Stress Response Potentiates Ponatinib-Induced Cardiotoxicity. Circulation Research (2024)

Gege YanZhenbo HanYoujeong KwonJordan JousmaSarath Babu NukalaBenjamin L. ProsserXiaoping DuSandra PinhoSang-Bing OngWon Hee LeeSang-Ging Ong

medicineintegrated stress responsecardiologycardiovascular toxicityponatinib-induced cardiotoxicitypharmacologyhealth sciencesmedicinal research

Matrimeres Are Systemic Nanoscale Mediators of Tissue Integrity and Function. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Koushik DebnathIrfan QayoomSteven O’DonnellJulia EkiertCan WangMark A. SanbornChang LiuAmbar RiveraIk Sung ChoSaiumamaheswari SaichellappaPeter T. TothDolly MehtaJalees RehmanXiaoping DuYu GaoJae-Won Shin

dermatologyneurosciencetissue integrityregenerative medicinecell-matrix interactionspharmacologynanomedicinesystemic nanoscale mediatorsnanobiotechnologynanotechnology

Thromboinflammation and the Role of Platelets. Arteriosclerosis Thrombosis and Vascular Biology (2024)

Andrew MackTerry Vanden HoekXiaoping Du

hematologyangiologycardiologyvascular biologyrespiratory medicinethrombosishealth sciences

A Critical Role for Ero1α in Arterial Thrombosis and Ischemic Stroke. Circulation Research (2023)

Vishwanath JhaBei XiongTripti KumariGavriel BrownJinzhi WangKyungho KimJingu LeeNathan AsquithJohn GallagherLillian AshermanTaylor LambertYanyan BaiXiaoping DuJeong-Ki MinRajan SahAli JavaheriBabak RazaniJin-Moo LeeJoseph E. ItalianoJaehyung Cho

hepatologyhematologycerebrovascular diseasecirculatory physiologyhemostasisstrokecardiologyarterial thrombosisischemic strokecritical roleblood flowpharmacologyvascular biologyvascular diseasecardiovascular researchneurologyhealth sciencescardiovascular disease

Integrin β3 Directly Inhibits the Gα13-P115Rhogef Interaction to Regulate G Protein Signaling and Platelet Exocytosis. Nature Communications (2023)

receptorsplatelet antagonistintegrin β3cytoskeletoncell biologycell signalingg proteincell-matrix interactionsimmunologyvascular biologyplatelet exocytosissignal transductionmolecular physiologyblood platelet

Abstract 10885: Integrin β 3 Directly Inhibits Galpha 13 -P115Rhogef Interaction and Its Role in Regulating Platelet Exocytosis. Circulation (2022)

hematologyplatelet antagonistcytoskeletonhemostasisblood cellsabstract 10885regulating platelet exocytosiscell biologycell signalingautophagycell and molecular biologysignal transductionthrombosismolecular medicinepathologyblood platelet

Platelet Ero1α is Crucial for Ca2+ Mobilization and Platelet Activation in Atherothrombosis. Blood (2022)

Vishwanath JhaTripti KumariBei XiongKyungho KimJingzhi WangGavriel BrownNathan AsquithJohn GallagherLillian AshermanYanyan BaiXiaoping DuJeong-Ki MinBabak RazaniJoseph E. ItalianoJin-Moo LeeJaehyung Cho

hepatologyhematologymedicineliver physiologycardiologyplatelet activationdermatologyvascular biologyrespiratory medicinephysiologycardiovascular researchblood platelet

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Xiaoping Du, MD, PhD

Professor

University of Illinois Chicago

Affiliations

College of Medicine of Chicago

Pharmacology and Regenerative Medicine

Xiaoping Du, Md, Phd is currently serving as a College Of Medicine Of Chicago Professor at University of Illinois Chicago.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Xiaoping Du, MD, PhD

University of Illinois Chicago

Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Platelet Factor 4 (Pf4) Regulates Hematopoietic Stem Cell Aging. Blood (2025)

aging cellhematologystem cell researchplatelet factor 4haematopoiesisstem cellscell biologythrombopoiesisstem cell mobilizationblood platelet

Tapping Into the Natural Pz-Independent Anticoagulant Function of Zpi to Inhibit Thrombosis With Minimal Effect on Hemostasis. Arteriosclerosis Thrombosis and Vascular Biology (2025)

hematologyanticoagulantsmedicinehemostasisthrombosisimmunologypharmacologyvascular biologyinhibit thrombosisminimal effectclinical researchpharmacotherapy

Abstract 2098: A Novel Mechanism of Focal Adhesion Kinase Activation by Integrins and Its Role in Outside-in Signaling in Platelets. Arteriosclerosis Thrombosis and Vascular Biology (2024)

Integrated Stress Response Potentiates Ponatinib-Induced Cardiotoxicity. Circulation Research (2024)

Gege YanZhenbo HanYoujeong KwonJordan JousmaSarath Babu NukalaBenjamin L. ProsserXiaoping DuSandra PinhoSang-Bing OngWon Hee LeeSang-Ging Ong

medicineintegrated stress responsecardiologycardiovascular toxicityponatinib-induced cardiotoxicitypharmacologyhealth sciencesmedicinal research

Matrimeres Are Systemic Nanoscale Mediators of Tissue Integrity and Function. bioRxiv (Cold Spring Harbor Laboratory) (2024)

dermatologyneurosciencetissue integrityregenerative medicinecell-matrix interactionspharmacologynanomedicinesystemic nanoscale mediatorsnanobiotechnologynanotechnology

Thromboinflammation and the Role of Platelets. Arteriosclerosis Thrombosis and Vascular Biology (2024)

Andrew MackTerry Vanden HoekXiaoping Du

hematologyangiologycardiologyvascular biologyrespiratory medicinethrombosishealth sciences

A Critical Role for Ero1α in Arterial Thrombosis and Ischemic Stroke. Circulation Research (2023)

Integrin β3 Directly Inhibits the Gα13-P115Rhogef Interaction to Regulate G Protein Signaling and Platelet Exocytosis. Nature Communications (2023)

Abstract 10885: Integrin β 3 Directly Inhibits Galpha 13 -P115Rhogef Interaction and Its Role in Regulating Platelet Exocytosis. Circulation (2022)

Platelet Ero1α is Crucial for Ca2+ Mobilization and Platelet Activation in Atherothrombosis. Blood (2022)

hepatologyhematologymedicineliver physiologycardiologyplatelet activationdermatologyvascular biologyrespiratory medicinephysiologycardiovascular researchblood platelet

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