Faculty

Institution

Unit

Venue

Xiao-Xin Sun

Assistant Professor of Molecular and Medical Genetics

Oregon Health & Science University

Affiliations

Division Of Genetics

Oregon Health & Science University

Oregon National Primate Research Center

Xiao-xin Sun is currently serving as a Division Of Genetics Assistant Professor of Molecular and Medical Genetics at Oregon Health & Science University.

Honors

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Experiences

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Education

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Xiao-Xin Sun

Oregon Health & Science University

Assistant Professor of Molecular and Medical Genetics

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molecular biology cell biology molecular and cellular biology biochemistry gene expression molecular cell biology tumor biology oncogenes genetics biological chemistry nucleic acids cancer biology rna biology protein function tumor suppressors enzymes protein science cell regulation protein synthesis cancer research cell signaling cancer genetics molecular regulation oncology structural biology enzyme inhibition structural molecular biology molecular cancer cellular biochemistry molecular metabolism clinical investigation proteome research cellular enzymology inhibitory activity microrna detection apoptosis chromatin remodeling nuclear organization viral genetics ribosomal protein c-myc expression vascular biology redox biology cell metabolism cancer discovery cancer genomics structure-function enzyme kinetics homeostatic mechanisms enzyme specificity late binding functional modification functional regulation tumor targeting protein biosynthesis disease progression protein phosphorylation biomedical modeling breast oncology tumor heterogeneity nucleic acid chemistry virus structure viral structural protein positive regulation aberrant expression post-ubiquitination mechanism ribosomal proteins parkin ubiquitinates tumor progression serine synthesis novel regulator mdm2-p53 loop ribosomal protein l4 proteasomal turnover myc ubiquitination suppress ubch5 enzyme stabilize p53 protein cell death dna repair metabolism pathology autophagy liver physiology transcription factors chemical biology tumor microenvironment metabolic engineering biochemical sciences biosynthesis transcription (biology) hepatology developmental biology cancer letter molecular physiology carcinogenesis pharmacology free radical biology systems biology molecular gastroenterology biomolecular engineering cancer cells metabolomics metabolic pathways signal transduction oxidative stress molecular medicine

Notable Scholarly Works

Notable Federal Grants

Collaborators

Myc Serine 62 Phosphorylation Promotes Its Binding to Dna Double Strand Breaks to Facilitate Repair and Cell Survival Under Genotoxic Stress. bioRxiv (Cold Spring Harbor Laboratory) (2025)

oncogenescell cyclechromatin remodelinggenome instabilitycell deathcell biologybiochemistrymyc serine 62dna replicationmolecular cell biologymolecular biologygenotoxic stresscell regulationdna repaircell survival

Supplementary Figure S5 From Usp36 Sumoylates Las1L and Promotes Its Function in Pre–Ribosomal Rna Its2 Processing. (2025)

molecular and cellular biologyusp36 sumoylates las1lrna processingnucleic acidscell biologysupplementary figure s5molecular cell biologynuclear organizationtranscription (biology)molecular biologybiological chemistryprotein synthesisgene expressionrna biology

Data From Usp36 Sumoylates Las1L and Promotes Its Function in Pre–Ribosomal Rna Its2 Processing. (2024)

molecular and cellular biologyusp36 sumoylates las1lrna processingbiomolecular structurenucleic acidscell biologybiochemistrymolecular cell biologytranscription (biology)molecular biologybiological chemistryprotein synthesisgene expressionstructural molecular biologyrna biology

Artificial Cells Delivering Itaconic Acid Induce Anti-Inflammatory Memory-Like Macrophages to Reverse Acute Liver Failure and Prevent Reinjury. Cell Reports Medicine (2023)

Supplementary Figure S3 From the Ubiquitin-Specific Protease Usp36 Associates With the Microprocessor Complex and Regulates Mirna Biogenesis by Sumoylating Dgcr8. (2023)

Yanping LiTimothy S. CareyCatherine H. FengHong-Ming ZhuXiao-Xin SunMu-Shui Dai

microprocessor complexepigeneticsdevelopmental biologymolecular biologymirna biogenesisviral geneticsrna biologygenetics

Detection of Post-Translational Modifications on Myc. Methods in molecular biology (2021)

computer-assisted translationcomputer sciencesoftware analysismolecular informaticspost-translational modificationsverificationbioinformaticsprogram analysis

The Deubiquitinase Usp36 Promotes Snornp Group Sumoylation and is Essential for Ribosome Biogenesis. EMBO Reports (2021)

Hyunju RyuXiao‐Xin SunYingxiao ChenYanping LiXiaoyan WangRoselyn S DaiHong‐Ming ZhuJohn KlimekLarry DavidLev M FedorovYoshiaki AzumaRosalie C SearsMu‐Shui Dai

enzymesprotein scienceprotein functionbiochemistrymembrane biologymolecular biologyribosome biogenesisgene expressionrna biologygenetics

Parkin Ubiquitinates Phosphoglycerate Dehydrogenase to Suppress Serine Synthesis and Tumor Progression. Journal of Clinical Investigation (2020)

Juan LiuCen ZhangHao WuXiao-Xin SunYanchen LiShan HuangXuetian YueShou-En LuZhiyuan ShenXiaoyang SuEileen WhiteBruce G. HafftyWenwei HuZhaohui Feng

parkin ubiquitinatesprotein phosphorylationdisease progressioncancer discoverytumor biologyenzymescell signalingtumor suppressorsmolecular biologygene expressionprotein biosynthesisinhibitory activityclinical investigationbiochemistryglycobiologycell metabolismmolecular metabolismtumor progressionserine synthesisenzyme inhibitionbiomolecular engineering

The Sumo‐Specific Protease Senp1 Desumoylates P53 and Regulates Its Activity. Journal of Cellular Biochemistry (2020)

Krishna M. ChauhanYingxiao ChenYiyi ChenAndrew T. LiuXiao‐Xin SunMu‐Shui Dai

molecular and cellular biologyoncogenesenzymesprotein sciencecell signalingcell biologyprotein functioncellular regulatory mechanismbiochemistrymolecular cell biologycellular biologymolecular biologycellular enzymologysignal transductioncellular biochemistrystructural biologyproteome research

Deregulating Myc in a Model of Her2+ Breast Cancer Mimics Human Intertumoral Heterogeneity. Journal of Clinical Investigation (2019)

Tyler RisomXiaoyan WangJuan LiangXiaoli ZhangCarl PelzLydia G. CampbellJenny EngKoei ChinCaroline FarringtonGoutham NarlaEllen M. LangerXiao-Xin SunYulong SuColin J. DanielMu-Shui DaiChristiane V. LöhrRosalie C. Sears

breast oncologyoncogenesbreast cancercancer biologymolecular modellingcell biologyclinical investigationmedicinal researchcancer imagingcancer researchmolecular biologyexperimental medicinebiomedical modelingclinical researchcancer geneticsoncologygeneticstumor heterogeneity

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Xiao-Xin Sun

Assistant Professor of Molecular and Medical Genetics

Oregon Health & Science University

Affiliations

Division Of Genetics

Oregon Health & Science University

Oregon National Primate Research Center

Xiao-xin Sun is currently serving as a Division Of Genetics Assistant Professor of Molecular and Medical Genetics at Oregon Health & Science University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Xiao-Xin Sun

Oregon Health & Science University

Assistant Professor of Molecular and Medical Genetics

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Myc Serine 62 Phosphorylation Promotes Its Binding to Dna Double Strand Breaks to Facilitate Repair and Cell Survival Under Genotoxic Stress. bioRxiv (Cold Spring Harbor Laboratory) (2025)

Supplementary Figure S5 From Usp36 Sumoylates Las1L and Promotes Its Function in Pre–Ribosomal Rna Its2 Processing. (2025)

Data From Usp36 Sumoylates Las1L and Promotes Its Function in Pre–Ribosomal Rna Its2 Processing. (2024)

Artificial Cells Delivering Itaconic Acid Induce Anti-Inflammatory Memory-Like Macrophages to Reverse Acute Liver Failure and Prevent Reinjury. Cell Reports Medicine (2023)

Supplementary Figure S3 From the Ubiquitin-Specific Protease Usp36 Associates With the Microprocessor Complex and Regulates Mirna Biogenesis by Sumoylating Dgcr8. (2023)

Yanping LiTimothy S. CareyCatherine H. FengHong-Ming ZhuXiao-Xin SunMu-Shui Dai

microprocessor complexepigeneticsdevelopmental biologymolecular biologymirna biogenesisviral geneticsrna biologygenetics

Detection of Post-Translational Modifications on Myc. Methods in molecular biology (2021)

computer-assisted translationcomputer sciencesoftware analysismolecular informaticspost-translational modificationsverificationbioinformaticsprogram analysis

The Deubiquitinase Usp36 Promotes Snornp Group Sumoylation and is Essential for Ribosome Biogenesis. EMBO Reports (2021)

Hyunju RyuXiao‐Xin SunYingxiao ChenYanping LiXiaoyan WangRoselyn S DaiHong‐Ming ZhuJohn KlimekLarry DavidLev M FedorovYoshiaki AzumaRosalie C SearsMu‐Shui Dai

enzymesprotein scienceprotein functionbiochemistrymembrane biologymolecular biologyribosome biogenesisgene expressionrna biologygenetics

Parkin Ubiquitinates Phosphoglycerate Dehydrogenase to Suppress Serine Synthesis and Tumor Progression. Journal of Clinical Investigation (2020)

Juan LiuCen ZhangHao WuXiao-Xin SunYanchen LiShan HuangXuetian YueShou-En LuZhiyuan ShenXiaoyang SuEileen WhiteBruce G. HafftyWenwei HuZhaohui Feng

The Sumo‐Specific Protease Senp1 Desumoylates P53 and Regulates Its Activity. Journal of Cellular Biochemistry (2020)

Krishna M. ChauhanYingxiao ChenYiyi ChenAndrew T. LiuXiao‐Xin SunMu‐Shui Dai

Deregulating Myc in a Model of Her2+ Breast Cancer Mimics Human Intertumoral Heterogeneity. Journal of Clinical Investigation (2019)

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5
10 / page