Faculty

Institution

Unit

Venue

William Holmes

Assistant Professor

Rhode Island College

Affiliations

Biology

Faculty of Arts and Sciences

Department of Biology

William Holmes is currently serving as a Biology Assistant Professor at Rhode Island College.

Honors

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Experiences

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Education

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William Holmes

Rhode Island College

Assistant Professor

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molecular biology biochemistry protein science protein folding biological chemistry cell biology protein structure enzymes molecular neurodegeneration cellular biochemistry protein function structural biology biochemical sciences proteome research molecular metabolism molecular cell biology protein expression yeast n‐terminal acetylation pharmacology membrane biology molecular neuroscience tumor biology crystallography redox biology medicinal research structural molecular biology fungal genetics molecular evidence molecular substrates functional modification molecular basis enzymatic modification protein x-ray crystallography protein chemistry purification method protein purification biochemical interaction biochemical genetics chemical pathology protein transport protein biosynthesis cellular enzymology molecular regulation amino-terminal acetylation prion phenotype substrate specificity fine tuning protein tau hsp70 chaperone ssa1 critical reviews microtubule‐associated protein tau ssa1 chaperone saccharomyces cerevisiae biology life science neurodegenerative diseases

Notable Scholarly Works

Notable Federal Grants

Collaborators

Expression and Purification of N‐Terminally Acetylated Ssa1 Chaperone From Saccharomyces Cerevisiae. The FASEB Journal (2020)

enzymessaccharomyces cerevisiaebiochemistrybiotechnologyssa1 chaperoneyeastfungal geneticsmolecular biologybiological chemistrycellular enzymologybiosynthesisprotein biosynthesis

The Effects of N‐Terminal Acetylation on the Protein Tau. The FASEB Journal (2020)

protein expressionprotein structuremolecular neurodegenerationprotein scienceprotein tauprotein functionbiochemistrymolecular biologybiological chemistryprotein folding

Expression of Microtubule Associated Protein Tau (Mapt) in Saccharomyces Cerevisiae to Determine the Effects of N‐Terminal Acetylation. The FASEB Journal (2019)

molecular and cellular biologyprotein expressionmolecular neurodegenerationn‐terminal acetylationmolecular metabolismcell biologymolecular cell biologyyeastmolecular regulationmolecular biologybiological chemistrygene expressioncellular biochemistryproteome research

Fine Tuning: Effects of Post-Translational Modification on Hsp70 Chaperones. International Journal of Molecular Sciences (2019)

protein chemistryprotein scienceprotein functionmolecular biologyprotein foldingfine tuning

A Highly Efficient, One-Step Purification of the Hsp70 Chaperone Ssa1. Protein Expression and Purification (2018)

protein structurehsp70 chaperone ssa1enzymespurification methodprotein purificationbiochemistrychemical biologymolecular biologyprotein folding

Determining the Effects of N‐Terminal Acetylation on the Microtubule‐Associated Protein Tau. The FASEB Journal (2018)

molecular and cellular biologymolecular neurodegenerationn‐terminal acetylationprotein sciencecell biologyprotein functioncytoskeletonmolecular cell biologyprotein transportmolecular biologyprotein foldingcellular biochemistrymicrotubule‐associated protein tau

Critical Reviews in Biochemistry and Molecular Biology 49 (2014): 294-303.. (2014)

molecular and cellular biologymolecular metabolismprotein sciencecritical reviewsbiochemistrychemical biologybiochemical sciencesmolecular biologybiological chemistrybiochemical interactionchemical pathologybiochemical geneticscellular biochemistryproteome researchcell and molecular biology

Loss of Amino-Terminal Acetylation Suppresses a Prion Phenotype by Modulating Global Protein Folding. Nature Communications (2014)

William M. HolmesBrian K. MannakeeRyan N. GutenkunstTricia R. Serio

amino-terminal acetylationtumor biologycell biologymolecular biologymolecular neuroscienceprotein foldingmedicinal researchbiochemistrymolecular basisfunctional modificationstructural biologyenzymatic modificationprion phenotypeprotein sciencemembrane biologybiochemical sciencesmolecular substratesredox biologymolecular evidence

Crystal Structure of Inositol Phosphate Multikinase 2 and Implications for Substrate Specificity. Journal of Biological Chemistry (2006)

William HolmesGerwald Jogl

protein x-ray crystallographyenzymesprotein sciencecrystallographybiochemistrypharmacologymolecular biologyprotein structurestructural molecular biologystructural biologysubstrate specificity

1
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William Holmes

Assistant Professor

Rhode Island College

Affiliations

Biology

Faculty of Arts and Sciences

Department of Biology

William Holmes is currently serving as a Biology Assistant Professor at Rhode Island College.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

William Holmes

Rhode Island College

Assistant Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Expression and Purification of N‐Terminally Acetylated Ssa1 Chaperone From Saccharomyces Cerevisiae. The FASEB Journal (2020)

enzymessaccharomyces cerevisiaebiochemistrybiotechnologyssa1 chaperoneyeastfungal geneticsmolecular biologybiological chemistrycellular enzymologybiosynthesisprotein biosynthesis

The Effects of N‐Terminal Acetylation on the Protein Tau. The FASEB Journal (2020)

protein expressionprotein structuremolecular neurodegenerationprotein scienceprotein tauprotein functionbiochemistrymolecular biologybiological chemistryprotein folding

Expression of Microtubule Associated Protein Tau (Mapt) in Saccharomyces Cerevisiae to Determine the Effects of N‐Terminal Acetylation. The FASEB Journal (2019)

Fine Tuning: Effects of Post-Translational Modification on Hsp70 Chaperones. International Journal of Molecular Sciences (2019)

protein chemistryprotein scienceprotein functionmolecular biologyprotein foldingfine tuning

A Highly Efficient, One-Step Purification of the Hsp70 Chaperone Ssa1. Protein Expression and Purification (2018)

protein structurehsp70 chaperone ssa1enzymespurification methodprotein purificationbiochemistrychemical biologymolecular biologyprotein folding

Determining the Effects of N‐Terminal Acetylation on the Microtubule‐Associated Protein Tau. The FASEB Journal (2018)

Critical Reviews in Biochemistry and Molecular Biology 49 (2014): 294-303.. (2014)

Loss of Amino-Terminal Acetylation Suppresses a Prion Phenotype by Modulating Global Protein Folding. Nature Communications (2014)

William M. HolmesBrian K. MannakeeRyan N. GutenkunstTricia R. Serio

Crystal Structure of Inositol Phosphate Multikinase 2 and Implications for Substrate Specificity. Journal of Biological Chemistry (2006)

William HolmesGerwald Jogl

protein x-ray crystallographyenzymesprotein sciencecrystallographybiochemistrypharmacologymolecular biologyprotein structurestructural molecular biologystructural biologysubstrate specificity

1
10 / page