Faculty

Institution

Unit

Venue

William F.C. Rigby, MD

Emeritus Professor of Medicine Emeritus Professor of Microbiology and Immunology

Dartmouth College

Affiliations

Geisel School of Medicine

Microbiology and Immunology

William F.c. Rigby, Md is currently serving as a Geisel School Of Medicine Emeritus Professor of Medicine Emeritus Professor of Microbiology and Immunology at Dartmouth College.

Honors

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Experiences

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Education

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William F.C. Rigby, MD

Dartmouth College

Emeritus Professor of Medicine Emeritus Professor of Microbiology and Immunology

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rheumatology immunology rheumatoid arthritis arthritis clinical rheumatology medicine inflammatory rheumatic disease rheumatoid disorder rheumatism autoimmune diseases pharmacology clinical trials immune responses pharmacotherapy clinical research cell biology autoimmunity inflammation molecular cell biology medicinal research psoriatic arthritis anti-inflammatory protein science systemic treatment nucleic acids biological chemistry inadequate response clinical microbiology autoinflammatory disease clinical immunology immunopathology structural molecular biology infection control molecular immunology immunologic mechanisms rna biology active rheumatoid arthritis cellular biochemistry virus research applied pharmacology signaling pathways cytokines inflammatory diseases cellular immune responses clinical dermatology cell regulation hla typing clinical therapeutics early rheumatoid arthritis mammalian biology aldehyde dehydrogenase protein synthesis molecular regulation adaptive immune system protein expression lymphocyte development protein function host genetics innate immune system drug safety clinical infection chronic inflammation mucosal immunology rituximab plus methotrexate mrna turnover human t lymphocytes hnrnp a2 subcutaneous tocilizumab cd40 ligand extracellular loop are-mrna decay tnf inhibitors double-blind phase 3 rossmann fold nad+-binding region mtx inadequate responders autoantibody production pathology mrna regulation

Notable Scholarly Works

Notable Federal Grants

Collaborators

Upadacitinib as Monotherapy in Patients With Rheumatoid Arthritis and Prior Inadequate Response to Methotrexate: Results at 260 Weeks From the Select-Monotherapy Randomised Study. RMD Open (2025)

rheumatoid arthritismedicineoncologyarthritisinflammatory rheumatic diseaseprior inadequate responsesystemic treatmentrheumatoid disorderpharmacologypsoriatic arthritisclinical rheumatologyrheumatismrheumatologypharmacotherapyclinical trials

Regulation of Neutrophil Myeloperoxidase Inhibitor Spin by the Small Rna Teg49 in Staphylococcus Aureus. Molecular Microbiology (2022)

Liviu CengherAdhar C. MannaJunho ChoJomkuan TheprungsirikulKatherine SessionsWilliam RigbyAmbrose L. Cheung

microbiologygene expressioninflammationmolecular microbiologymicrobial pathogenesisdrug resistancetranscription (biology)clinical microbiologyredox biologyimmunologyvascular biologyfree radical biologyinnate immune systemmedical microbiologybacteriologymolecular biologyenzyme inhibitionsmall rna

Regulation of Neutrophil Myeloperoxidase Inhibitor Spin by the Small Rna Teg49 in Staphylococcus Aureus.. Mol Microbiol (2022)

small rna teg49microbiologypathogenic bacteriaantimicrobial agentsmolecular microbiologymicrobial pathogenesisstaphylococcus aureusclinical microbiologybiological chemistrybiochemistryrna biologybacteriologyvirulence factorsantimicrobial resistancemolecular biologymedical microbiology

The Thematic Role of Extracellular Loop of Vrag in Activation of the Membrane Sensor Gras in a Cystic Fibrosis Mrsa Strain Differs in Nuance From the Ca-Mrsa Strain Je2. PLoS ONE (2022)

Junho ChoWilliam F. C. RigbyAmbrose L. Cheung

microbiologymembrane sensor grasmembrane transportextracellular loopdrug resistanceprotein sciencecystic fibrosismembrane proteinssystems biologyclinical microbiologymembrane biologymembranesvascular biologykey sitepathogen detectionmolecular biologythematic rolevirus research

Bactericidal/Permeability-Increasing Protein Preeminently Mediates Clearance of Pseudomonas Aeruginosa in Vivo via Cd18-Dependent Phagocytosis. Frontiers in Immunology (2021)

Jomkuan TheprungsirikulSladjana Skopelja-GardnerAshley S. BurnsRachel M. WierzbickiWilliam F. C. Rigby

antimicrobial resistancemicrobiologypathogenic bacteriaimmune responsesimmunologic mechanismsinfection controlinfectious diseasesmicrobial pathogenesismolecular immunologyclinical microbiologyimmunologyvascular biologymucosal immunologypathogensimmunopathologyphagocytes

Benefit–Risk Analysis of Upadacitinib Compared With Adalimumab in the Treatment of Patients With Moderate-To-Severe Rheumatoid Arthritis. Rheumatology and Therapy (2021)

rheumatoid arthritismoderate-to-severe rheumatoid arthritismedicinebenefit–risk analysisinflammatory rheumatic diseasearthritisupadacitinib comparedclinical rheumatologysystemic treatmentclinical therapeuticsrheumatoid disorderpsoriatic arthritisrheumatologyclinical researchhealth sciencespharmacotherapy

Differential Enhancement of Neutrophil Phagocytosis by Anti–Bactericidal/Permeability-Increasing Protein Antibodies. The Journal of Immunology (2021)

Jomkuan TheprungsirikulSladjana Skopelja-GardnerRachel M. WierzbickiKatherine J. SessionsWilliam F. C. Rigby

immune responsesimmunologic mechanismsantibody engineeringneutrophil phagocytosisclinical immunologyimmunologyimmunopathologyphagocytes

Filgotinib in Combination With Methotrexate or as Monotherapy Versus Methotrexate Monotherapy in Patients With Active Rheumatoid Arthritis and Limited or No Prior Exposure to Methotrexate: The Phase 3, Randomised Controlled Finch 3 Trial. Annals of the Rheumatic Diseases (2021)

René WesthovensWilliam F C RigbyDésirée van der HeijdeDaniel W T ChingWilliam StohlJonathan KayArvind ChopraBeatrix BartokFranziska MatzkiesZhaoyu YinYing GuoChantal TassetJohn S SundyAngelika JahreisNeelufar MozaffarianOsvaldo Daniel MessinaRobert BM LandewéTatsuya AtsumiGerd R Burmester

rheumatoid arthritismedicineautoimmune diseasesinflammatory rheumatic diseasearthritisactive rheumatoid arthritisclinical rheumatologyrheumatoid disorderrheumatologyprior exposureclinical researchclinical trials

Hla-Drb1 Risk Alleles for Ra Are Associated With Differential Clinical Responsiveness to Abatacept and Adalimumab: Data From a Head-To-Head, Randomized, Single-Blind Study in Autoantibody-Positive Early Ra. Arthritis Research & Therapy (2021)

William RigbyJane H. BucknerS. Louis BridgesMarleen NysSheng GaoMartin PolinskyNeelanjana RayVivian Bykerk

clinical evidencemedicinebiostatisticshla typingrheumatologyrheumatoid arthritissingle-blind studycohort studiesquantitative science studiesclinical immunologygeneticsdifferential clinical responsivenessarthritisclinical epidemiologyhost geneticssurvival analysismedicinal researchautoantibody-positive early raclinical rheumatologyexperimental medicineclinical research

Journal Club: Efficacy of Tocilizumab in Early Systemic Sclerosis–Related Interstitial Lung Disease. ACR Open Rheumatology (2021)

chronic obstructive pulmonary diseaseautoimmune diseasessystemic sclerodermaadvanced lung diseasesclerodermainterstitial lung diseaseimmunologyautoimmunityrespiratory medicinejournal clubpulmonary diseasesallergy

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William F.C. Rigby, MD

Emeritus Professor of Medicine Emeritus Professor of Microbiology and Immunology

Dartmouth College

Affiliations

Geisel School of Medicine

Microbiology and Immunology

William F.c. Rigby, Md is currently serving as a Geisel School Of Medicine Emeritus Professor of Medicine Emeritus Professor of Microbiology and Immunology at Dartmouth College.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

William F.C. Rigby, MD

Dartmouth College

Emeritus Professor of Medicine Emeritus Professor of Microbiology and Immunology

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Upadacitinib as Monotherapy in Patients With Rheumatoid Arthritis and Prior Inadequate Response to Methotrexate: Results at 260 Weeks From the Select-Monotherapy Randomised Study. RMD Open (2025)

Regulation of Neutrophil Myeloperoxidase Inhibitor Spin by the Small Rna Teg49 in Staphylococcus Aureus. Molecular Microbiology (2022)

Liviu CengherAdhar C. MannaJunho ChoJomkuan TheprungsirikulKatherine SessionsWilliam RigbyAmbrose L. Cheung

Regulation of Neutrophil Myeloperoxidase Inhibitor Spin by the Small Rna Teg49 in Staphylococcus Aureus.. Mol Microbiol (2022)

The Thematic Role of Extracellular Loop of Vrag in Activation of the Membrane Sensor Gras in a Cystic Fibrosis Mrsa Strain Differs in Nuance From the Ca-Mrsa Strain Je2. PLoS ONE (2022)

Junho ChoWilliam F. C. RigbyAmbrose L. Cheung

Bactericidal/Permeability-Increasing Protein Preeminently Mediates Clearance of Pseudomonas Aeruginosa in Vivo via Cd18-Dependent Phagocytosis. Frontiers in Immunology (2021)

Jomkuan TheprungsirikulSladjana Skopelja-GardnerAshley S. BurnsRachel M. WierzbickiWilliam F. C. Rigby

Benefit–Risk Analysis of Upadacitinib Compared With Adalimumab in the Treatment of Patients With Moderate-To-Severe Rheumatoid Arthritis. Rheumatology and Therapy (2021)

Differential Enhancement of Neutrophil Phagocytosis by Anti–Bactericidal/Permeability-Increasing Protein Antibodies. The Journal of Immunology (2021)

Jomkuan TheprungsirikulSladjana Skopelja-GardnerRachel M. WierzbickiKatherine J. SessionsWilliam F. C. Rigby

immune responsesimmunologic mechanismsantibody engineeringneutrophil phagocytosisclinical immunologyimmunologyimmunopathologyphagocytes

William RigbyJane H. BucknerS. Louis BridgesMarleen NysSheng GaoMartin PolinskyNeelanjana RayVivian Bykerk

Journal Club: Efficacy of Tocilizumab in Early Systemic Sclerosis–Related Interstitial Lung Disease. ACR Open Rheumatology (2021)

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igg fc receptors

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Stanford University

immunology

autoantibody production

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cellular therapy

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