Faculty

Institution

Unit

Venue

William R. Drobyski, MD

Professor of Medicine Pediatrics and Microbiology & Immunology

Medical College of Wisconsin

Affiliations

Bone Marrow Transplant Program

William R. Drobyski, Md is currently serving as a Bone Marrow Transplant Program Professor of Medicine Pediatrics and Microbiology & Immunology at Medical College of Wisconsin.

Honors

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Experiences

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Education

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William R. Drobyski, MD

Medical College of Wisconsin

Professor of Medicine Pediatrics and Microbiology & Immunology

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immunology hematology bone marrow transplantation cell transplantation clinical transplantation transplantation medicine immune responses medicine graft rejection oncology organ transplantation regenerative medicine graft survival stem cell transplantation pharmacology dermatology immunity (medicine) leukemia immunotherapy transplant infectious diseases cellular therapy t-regulatory cell medicinal research cellular immune responses clinical immunology adaptive immune system autoimmunity hematological malignancies cytokines cell therapy graft-versus-host disease multiple myeloma donor leukocyte infusions stem cell research digestive diseases mucosal immunology liver transplantation immunopathology lymphoid neoplasia chronic graft-versus-host disease cancer care vascular biology therapeutic efficacy cancer treatment novel therapies immune dysregulation medical virology clinical microbiology transplant surgery lymphocyte development innate immune system chronic myelogenous leukemia allogeneic transplantation engraftment syndrome infection control cancer biology blood cells immunomodulation t-cell depletion hematopoietic cell transplantation xenotransplantation clinical mycology clinical infectious disease stem-cell therapy immunologic mechanisms molecular immunology host response polymerase chain reaction tissue transplantation emerging infectious diseases salvage immunotherapy marrow transplantation minimal residual disease unrelated marrow transplantation hematologic malignancies unrelated marrow grafts translational studies translational research inflammatory pathways inflammation

Notable Scholarly Works

Notable Federal Grants

Collaborators

Intestinal Epithelium–Derived Il-34 Reprograms Macrophages to Mitigate Gastrointestinal Tract Graft-Versus-Host Disease. Science Translational Medicine (2025)

Aditya RayasamAlison MoeMatthew KudekRavi K. ShahCheng-Yin YuanJames M. MillerMary RauMollie PattonKarolyn WanatMarco ColonnaAnthony E. ZamoraWilliam R. Drobyski

immunologygut microbesmedicineclinical immunologytranslational researchmucosal immunologyimmune responsesimmunity (medicine)microbiologytranslational medicineinflammation

Tocilizumab Prophylaxis in Double Cord Blood Transplantation. Blood Advances (2025)

medicineorgan transplantationhematologytocilizumab prophylaxistransplant infectious diseasestransplantation medicineclinical trialsclinical researchcord bloodclinical transplantation

An Interleukin 27 Dependent Lysosomal Thiol Reductase Regulates Regulatory T Cell Survival and Mitochondrial Fitness During Graft Versus Host Disease. Blood (2024)

Jonathan FlorentinAlison MoeRavi K ShahJacek ZielonkaMark CastleberryAlex MyersMarlenny Vargas-CortesJessica L SchmelingAnthony E ZamoraWilliam R Drobyski

immunologygraft rejectioncellular immune responsesimmune dysregulationmolecular biologymitochondrial fitnessimmune responsest-regulatory cellgraft survival

Bhlhe40 Promotes Cd4+ T Helper 1 Cell and Suppresses T Follicular Helper Cell Differentiation During Viral Infection. The Journal of Immunology (2024)

Christine NguyenMatthew KudekRyan ZanderHongshen NiuJian ShenAshley BauerDonia AlsonAchia KhatunYao ChenJie SunWilliam DrobyskiBrian T. EdelsonWeiguo Cui

immunologyrespiratory infectionscellular immune responsesinnate immune systemadaptive immune systemvirologyviral infectionimmune responsescell biology

Early Safety and Feasibility Results From a Phase II Trial of De-Escalated Ptcy and Ruxolitinib for Gvhd Prophylaxis in Older Patients Undergoing Reduced Intensity Conditioning Allogeneic Hct. Blood (2024)

Sameem AbedinFateeha FurqanLyndsey RunaasWalter LongoNirav N. ShahTimothy S. FenskeMarcelo C. PasquiniWilliam R DrobyskiXue-Zhong YuMehdi Hamadani

medicinepatient safetyearly safetyphase ii trialde-escalated ptcygvhd prophylaxisolder patients

Severity and Organ Distribution of Chronic Graft-Versus-Host Disease With Posttransplant Cyclophosphamide-Based Versus Methotrexate/Calcineurin Inhibitor-Based Allogeneic Hematopoietic Cell Transplantation. Bone Marrow Transplantation (2024)

Saurabh ChhabraJames H. JerkinsKathleen MonahanAniko SzaboNirav N. ShahSameem AbedinLyndsey RunaasTimothy S. FenskeMarcelo C. PasquiniBronwen E. ShawWilliam R. DrobyskiWael SaberAnita D’SouzaBinod DhakalMeera MohanWalter LongoMehdi Hamadani

chronic graft-versus-host diseasemedicinepharmacologyorgan transplantationhematologyregenerative medicineorgan distributiontransplant surgerytransplantation medicinebone marrow transplantationcell transplantationorthopaedic surgery

Type 2 Cannabinoid Receptor Expression on Microglial Cells Regulates Neuroinflammation During Graft-Versus-Host Disease. Journal of Clinical Investigation (2024)

Alison MoeAditya RayasamGarrett SauberRavi K. ShahAshley DohertyCheng-Yin YuanAniko SzaboBob M. MooreMarco ColonnaWeiguo CuiJulian RomeroAnthony E. ZamoraCecilia J. HillardWilliam R. Drobyski

peptidesneurological functiontherapeutic efficacycannabinoid receptor expressioncell biologyneurologyvascular biologyfunctional regulationcentral nervous systembiomarkersmicroglial cellsregenerative medicinepeptide sciencegraft-versus-host diseaseaddiction biologysomatic variantlate bindingoncologyclinical researchmedicinal researchneuroscience

Interleukin-9 Production by Type 2 Innate Lymphoid Cells Induces Paneth Cell Metaplasia and Small Intestinal Remodeling. Nature Communications (2023)

Chengyin YuanAditya RayasamAlison MoeMichael HaywardClive WellsAniko SzaboAndrew MackenzieNita SalzmanWilliam R. Drobyski

immunologycell metaplasiacytokineslymphoid neoplasiainnate immune systemmucosal immunologyinnate lymphoid cellsimmune responsesimmunity (medicine)small intestinal remodelinglymphocyte developmentinflammation

Intestinal Epithelial-Derived Il-34 Regulates Macrophage Polarization in an Apolipoprotein E Dependent Manner and Mitigates the Severity of Graft Versus Host Disease. Blood (2023)

Aditiya RayasamAlison MoeRavi ShahCheng-Yin YuanMarco ColonnaJames MillerAnthony ZamoraWilliam Drobyski

immunologyimmune dysregulationimmune responsesinflammation

Microglial Cell Expression of the Type 2 Cannabinoid Receptor Regulates Immune-Mediated Neuroinflammation. bioRxiv (Cold Spring Harbor Laboratory) (2023)

Alison MoeAditya RayasamGarrett SauberRavi K. ShahCheng-Yin YuanAniko SzaboBob M. MooreMarco ColonnaWeiguo CuiJulian RomeroAnthony E. ZamoraCecilia J. HillardWilliam R. Drobyski

immunologyneurologyreceptorsneuroinflammationmicroglial cell expressioncannabinoid receptorneuropharmacologyimmune-mediated neuroinflammationneuroscience

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William R. Drobyski, MD

Professor of Medicine Pediatrics and Microbiology & Immunology

Medical College of Wisconsin

Affiliations

Bone Marrow Transplant Program

William R. Drobyski, Md is currently serving as a Bone Marrow Transplant Program Professor of Medicine Pediatrics and Microbiology & Immunology at Medical College of Wisconsin.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

William R. Drobyski, MD

Medical College of Wisconsin

Professor of Medicine Pediatrics and Microbiology & Immunology

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Intestinal Epithelium–Derived Il-34 Reprograms Macrophages to Mitigate Gastrointestinal Tract Graft-Versus-Host Disease. Science Translational Medicine (2025)

Aditya RayasamAlison MoeMatthew KudekRavi K. ShahCheng-Yin YuanJames M. MillerMary RauMollie PattonKarolyn WanatMarco ColonnaAnthony E. ZamoraWilliam R. Drobyski

immunologygut microbesmedicineclinical immunologytranslational researchmucosal immunologyimmune responsesimmunity (medicine)microbiologytranslational medicineinflammation

Tocilizumab Prophylaxis in Double Cord Blood Transplantation. Blood Advances (2025)

medicineorgan transplantationhematologytocilizumab prophylaxistransplant infectious diseasestransplantation medicineclinical trialsclinical researchcord bloodclinical transplantation

An Interleukin 27 Dependent Lysosomal Thiol Reductase Regulates Regulatory T Cell Survival and Mitochondrial Fitness During Graft Versus Host Disease. Blood (2024)

Jonathan FlorentinAlison MoeRavi K ShahJacek ZielonkaMark CastleberryAlex MyersMarlenny Vargas-CortesJessica L SchmelingAnthony E ZamoraWilliam R Drobyski

immunologygraft rejectioncellular immune responsesimmune dysregulationmolecular biologymitochondrial fitnessimmune responsest-regulatory cellgraft survival

Bhlhe40 Promotes Cd4+ T Helper 1 Cell and Suppresses T Follicular Helper Cell Differentiation During Viral Infection. The Journal of Immunology (2024)

Christine NguyenMatthew KudekRyan ZanderHongshen NiuJian ShenAshley BauerDonia AlsonAchia KhatunYao ChenJie SunWilliam DrobyskiBrian T. EdelsonWeiguo Cui

immunologyrespiratory infectionscellular immune responsesinnate immune systemadaptive immune systemvirologyviral infectionimmune responsescell biology

Sameem AbedinFateeha FurqanLyndsey RunaasWalter LongoNirav N. ShahTimothy S. FenskeMarcelo C. PasquiniWilliam R DrobyskiXue-Zhong YuMehdi Hamadani

medicinepatient safetyearly safetyphase ii trialde-escalated ptcygvhd prophylaxisolder patients

Type 2 Cannabinoid Receptor Expression on Microglial Cells Regulates Neuroinflammation During Graft-Versus-Host Disease. Journal of Clinical Investigation (2024)

Alison MoeAditya RayasamGarrett SauberRavi K. ShahAshley DohertyCheng-Yin YuanAniko SzaboBob M. MooreMarco ColonnaWeiguo CuiJulian RomeroAnthony E. ZamoraCecilia J. HillardWilliam R. Drobyski

Interleukin-9 Production by Type 2 Innate Lymphoid Cells Induces Paneth Cell Metaplasia and Small Intestinal Remodeling. Nature Communications (2023)

Chengyin YuanAditya RayasamAlison MoeMichael HaywardClive WellsAniko SzaboAndrew MackenzieNita SalzmanWilliam R. Drobyski

Intestinal Epithelial-Derived Il-34 Regulates Macrophage Polarization in an Apolipoprotein E Dependent Manner and Mitigates the Severity of Graft Versus Host Disease. Blood (2023)

Aditiya RayasamAlison MoeRavi ShahCheng-Yin YuanMarco ColonnaJames MillerAnthony ZamoraWilliam Drobyski

immunologyimmune dysregulationimmune responsesinflammation

Microglial Cell Expression of the Type 2 Cannabinoid Receptor Regulates Immune-Mediated Neuroinflammation. bioRxiv (Cold Spring Harbor Laboratory) (2023)

Alison MoeAditya RayasamGarrett SauberRavi K. ShahCheng-Yin YuanAniko SzaboBob M. MooreMarco ColonnaWeiguo CuiJulian RomeroAnthony E. ZamoraCecilia J. HillardWilliam R. Drobyski

immunologyneurologyreceptorsneuroinflammationmicroglial cell expressioncannabinoid receptorneuropharmacologyimmune-mediated neuroinflammationneuroscience

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