Faculty

Institution

Unit

Venue

William Chilian

Kent State University

Affiliations

School of Biomedical Sciences

Cellular & Molecular Biology

Pharmacology

Physiology

College of Arts and Sciences

School of Biomedical Sciences

NoneWilliam Chilian is currently serving as a Cellular & Molecular Biology faculty at Kent State University.

Honors

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Experiences

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Education

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William Chilian

Kent State University

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cardiology physiology vascular biology cardiovascular research health sciences cardiovascular physiology circulatory physiology respiratory medicine pharmacology electrophysiology cardiovascular disease angiology hematology cellular physiology regenerative medicine membrane biology angiogenesis neuroscience human physiology liver physiology redox biology cardiovascular function coronary collateral growth molecular physiology mammalian biology applied physiology animal physiology mitochondrial function endothelial dysfunction atherosclerosis thrombosis neurophysiology metabolic syndrome coronary microcirculation stem cell research cardiomyopathy myocardial infarction coronary artery disease vascular disease mammalian physiology redox signaling arterial disease veterinary physiology mechanotransduction hemostasis vascular adaptation blood flow reperfusion injury cerebrovascular disease in vivo systems tissue physiology coronary arterioles coronary microvascular dysfunction avian biology ischemic syndrome rna biology tissue development nuclear cardiology cardiovascular pharmacology gene function microvascular dysfunction coronary circulation nitric oxide myocardial ischemia endothelium-dependent vasodilation cellular biology coronary microvascular resistance cardiac myocytes acute myocardial infarction protein expression flow-induced dilation cardiac fibroblast differentiation coronary microvascular responses collateral circulation canine coronary microcirculation ischemic heart disease molecular neurodegeneration neuroinflammation brain-immune interaction metabolomics molecular psychiatry alzheimer's disease cell metabolism neurology

Notable Scholarly Works

Notable Federal Grants

Collaborators

Does Coronary Microvascular Dysfunction Play a Role in Heart Failure With Reduced Ejection Fraction?. Journal of Molecular and Cellular Cardiology (2025)

Parisa ShabaniFeng DongJune YunSong Yi ShinAmber DinchmanDipan KunduAdam GoodwillJames GaddThomas PucciChristopher KolzLindsay ShocklingLiya YinWilliam ChilianVahagn Ohanyan

molecular and cellular biologycardiovascular researchheart failurecardiologymicrovascular dysfunctioncardiovascular diseasereduced ejection fractionmolecular biologycoronary microvascular dysfunction

Bone Marrow Cells Contribute to Seven Different Endothelial Cell Populations in the Heart. Basic Research in Cardiology (2024)

Parisa ShabaniVahagn OhanyanAmmar AlghadeerDaniel GavazziFeng DongLiya YinChristopher KolzLindsay ShocklingMolly EnrickPing ZhangXin ShiWilliam Chilian

hematologybone marrow cellscardiologyhealth sciencesdermatologycardiovascular researchvascular biology

Exosomal Mirnas and Isomirs: Potential Biomarkers for Type 2 Diabetes Mellitus. Precision Clinical Medicine (2024)

Yong Ling SouWilliam M ChilianWickneswari RatnamShamsul Mohd ZainSharifah Zamiah Syed Abdul KadirYan PanYuh-Fen Pung

medicinebiomarkerspotential biomarkersdiabetes mellitusexosomal mirnas

Exosome Derived From Nampt-Overexpressed Mesenchymal Stem Cell Improves Aortic Valve Stenosis Outcome via Downregulation of Mir-146A-3P Expression. Journal of Pharmacology and Experimental Therapeutics (2024)

Dipan Kumar KunduSong Yi ShinJames GaddThomas FanningVahagn OhanyanLiya YinWilliam ChilianFeng Dong

microrna detectionfunctional genomicsstem cell researchgene expression profilingregenerative medicinevalve diseasestem cellstranscription (biology)cell biologygene expressionpharmacologyenzyme inhibitionmesenchymal stem cellsprotein sciencemedicinal researchangiogenesismolecular biologyvascular biology

Increasing Hccs Function in Vivo Mediates Restoring Heme Integrity, Limiting Superoxide Overproduction, and Conferring Reconditioning Mitochondrial Function in the Acute Postischemic Heart. Physiology (2024)

Chwen-Lih ChenThomas PucciVahagn OhanyanWilliam ChilianYeong-Renn Chen

superoxide overproductionredox biologyneurophysiologyhuman biologycardiovascular researchhuman physiologyelectrophysiologymitochondrial functionheme homeostasismolecular physiologymembrane biologyapplied physiologyheme integrityhccs functionhemostasisacute postischemic heartregenerative medicinecellular physiologyphysiologygeneticsphysiological researchhealth sciences

The Potential of Mesenchymal Stem Cell-Derived Exosomes in Cardiac Repair. International Journal of Molecular Sciences (2024)

Dipan KunduSong Yi ShinWilliam M. ChilianFeng Dong

stem cell researchcell biologycell replacement therapiesstem-cell therapycardiac musclecell therapymolecular sciencebiomedical engineeringcellular therapymolecular biologytissue engineeringcell transplantationextracellular matrixregenerative medicineregeneration (biology)stem cellscardiac repairmesenchymal stem cellsvascular biology

Abstract 14877: Spike Protein of Sars-Cov-2 Virus Induces Mitochondrial Dysfunction in Swine Heart via Redox Impairment of Heme Proteins and Increasing Superoxide Generation. Circulation (2023)

Yeong-Renn ChenChwen-lih ChenChris KolzPatrick T KangWilliam LynchAngelo L DeLuciaWilliam M Chilian

viral replicationviral geneticsmammalian biologyredox biologyheme proteinsredox impairmentvirus researchmitochondrial functionmolecular biologygeneral virologysuperoxide generationcirculatory physiologyswine heartcardiologyvirologyspike proteinviral evolutionoxidative stressphysiologysars-cov-2veterinary medicineepidemiologyswine virus

Abstract 692: The Mechanism of Impaired Coronary Collateral Growth in Metabolic Syndromes. Arteriosclerosis Thrombosis and Vascular Biology (2023)

Yang WangAnurag JamaiyarCody JuguilonMolly EnrickJames GaddChris KolzSarah DongVahagn A OhanyanWilliam M ChilianZhenyu JiaLiya Yin

hematologycardiovascular functionrespiratory medicineangiologyhepatologycirculatory physiologyemergency medicineepidemiologycardiologythrombosishealth sciencesclinical lipidologynephrologyarterial diseasehumanity and medicineatherosclerosisvascular biology

Abstract P1032: Substrate Optimization for Patients With Melas and Leigh Syndrome Using Induced Pluripotent Stem Cells-Derived Cardiomyocytes. Circulation Research (2023)

Taylor H YamamotoConstance C HuangAva K CutrightKenan C DinchmanBruce H CohenWilliam M ChilianPatrick T Kang

stem cell researchgenetic engineeringcatalytic applicationscell engineeringoptimal experimental designclinical transplantationmedicinal researchbiomedical engineeringangiogenesistissue engineeringleigh syndromecardiologypharmacologycell transplantationdermatologysubstrate optimizationregenerative medicineapplied geneticsstem cell transplantationvascular biology

Changes in Mitochondrial Epigenome in Type 2 Diabetes Mellitus. British Journal of Biomedical Science (2023)

Hui Ching LowWilliam M. ChilianWickneswari RatnamTilakavati KarupaiahMohd Fairulnizal Md NohFazliana MansorZhi Xiang NgYuh Fen Pung

epigeneticsbiologybiomedical researchhuman geneticsepigenomicsepidemiologybiomedical analysisbiomedical data sciencegenetic epidemiologyhealth sciencesdiabetes mellitusepigenetic changesdiabetesmitochondrial epigenome

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William Chilian

Kent State University

Affiliations

School of Biomedical Sciences

Cellular & Molecular Biology

Pharmacology

Physiology

College of Arts and Sciences

School of Biomedical Sciences

NoneWilliam Chilian is currently serving as a Cellular & Molecular Biology faculty at Kent State University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

William Chilian

Kent State University

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Does Coronary Microvascular Dysfunction Play a Role in Heart Failure With Reduced Ejection Fraction?. Journal of Molecular and Cellular Cardiology (2025)

Parisa ShabaniFeng DongJune YunSong Yi ShinAmber DinchmanDipan KunduAdam GoodwillJames GaddThomas PucciChristopher KolzLindsay ShocklingLiya YinWilliam ChilianVahagn Ohanyan

molecular and cellular biologycardiovascular researchheart failurecardiologymicrovascular dysfunctioncardiovascular diseasereduced ejection fractionmolecular biologycoronary microvascular dysfunction

Bone Marrow Cells Contribute to Seven Different Endothelial Cell Populations in the Heart. Basic Research in Cardiology (2024)

Parisa ShabaniVahagn OhanyanAmmar AlghadeerDaniel GavazziFeng DongLiya YinChristopher KolzLindsay ShocklingMolly EnrickPing ZhangXin ShiWilliam Chilian

hematologybone marrow cellscardiologyhealth sciencesdermatologycardiovascular researchvascular biology

Exosomal Mirnas and Isomirs: Potential Biomarkers for Type 2 Diabetes Mellitus. Precision Clinical Medicine (2024)

Yong Ling SouWilliam M ChilianWickneswari RatnamShamsul Mohd ZainSharifah Zamiah Syed Abdul KadirYan PanYuh-Fen Pung

medicinebiomarkerspotential biomarkersdiabetes mellitusexosomal mirnas

Dipan Kumar KunduSong Yi ShinJames GaddThomas FanningVahagn OhanyanLiya YinWilliam ChilianFeng Dong

Chwen-Lih ChenThomas PucciVahagn OhanyanWilliam ChilianYeong-Renn Chen

The Potential of Mesenchymal Stem Cell-Derived Exosomes in Cardiac Repair. International Journal of Molecular Sciences (2024)

Dipan KunduSong Yi ShinWilliam M. ChilianFeng Dong

Abstract 14877: Spike Protein of Sars-Cov-2 Virus Induces Mitochondrial Dysfunction in Swine Heart via Redox Impairment of Heme Proteins and Increasing Superoxide Generation. Circulation (2023)

Yeong-Renn ChenChwen-lih ChenChris KolzPatrick T KangWilliam LynchAngelo L DeLuciaWilliam M Chilian

Abstract 692: The Mechanism of Impaired Coronary Collateral Growth in Metabolic Syndromes. Arteriosclerosis Thrombosis and Vascular Biology (2023)

Yang WangAnurag JamaiyarCody JuguilonMolly EnrickJames GaddChris KolzSarah DongVahagn A OhanyanWilliam M ChilianZhenyu JiaLiya Yin

Abstract P1032: Substrate Optimization for Patients With Melas and Leigh Syndrome Using Induced Pluripotent Stem Cells-Derived Cardiomyocytes. Circulation Research (2023)

Taylor H YamamotoConstance C HuangAva K CutrightKenan C DinchmanBruce H CohenWilliam M ChilianPatrick T Kang

Changes in Mitochondrial Epigenome in Type 2 Diabetes Mellitus. British Journal of Biomedical Science (2023)

Hui Ching LowWilliam M. ChilianWickneswari RatnamTilakavati KarupaiahMohd Fairulnizal Md NohFazliana MansorZhi Xiang NgYuh Fen Pung

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