Faculty

Institution

Unit

Venue

William Brunken

Upstate Medical University

Affiliations

Center For Vision Research

Department Of Ophthalmology And Visual Science

Center For Vision Research

College of Graduate Studies

Department Of Ophthalmology And Visual Science

Norton College of Medicine

Department Of Anesthesiology

Department Of Neuroscience And Physiology

Department Of Psychiatry And Behavioural Neuroscience

Institute Of Crouse Neuroscience

Department Of Anesthesiology

Norton College Of Medicine

Upstate Medical University

NoneWilliam Brunken is currently serving as a Center For Vision Research faculty at Upstate Medical University.

Honors

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Experiences

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Education

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William Brunken

Upstate Medical University

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ophthalmology retina ophthalmology retina cell biology neuroscience cellular physiology neurons visual science photoreceptor cells vascular biology developmental biology neuro-ophthalmology developmental neurobiology matrix biology membrane biology developmental cell ganglion cell molecular cell biology gene expression cell signaling angiogenesis neuropsychopharmacology cellular biochemistry nervous system molecular physiology cellular neurobiology ocular disease vision research neurophysiology ocular surface protein science cellular structure rabbit retina ocular tissues cell-matrix interactions developmental system stem cell research neurotransmission neuroinflammation optic nerve experimental ophthalmology cell adhesion biological macromolecules visual pathways neurotransmitters molecular neurobiology mouse retina membrane science ocular pathology cell migration intracellular trafficking rat retina cns synapses mammalian retina membrane systems connective tissue disease human tissues cancer genetics plant genetics developmental genetics animal genetics cerebrovascular disease cancer biology cell physiology cellular biology laminin expression non-basement membrane-associated laminin chain laminin γ3 chain collagen xxii rod pathways epithelial behavior novel member netrin family β chain s-laminin expression gene therapy translational research cell research regeneration (biology) molecular psychiatry extracellular matrix optogenetics nature method stem cells cellular differentiation nucleic acids functional genomics regenerative medicine neurogenetics xenotransplantation molecular and cellular biology mammalian biology molecular neuroscience molecular neurodegeneration cancer letter biotechnology advance tissue (biology) synthetic biology cell engineering biomedical informatics biomedical engineering genome editing experimental medicine systems biology genetics morphogenesis biomolecular engineering molecular biology oncogenes epigenetics molecular medicine

Notable Scholarly Works

Notable Federal Grants

Collaborators

Glutamatergic Neuronal Activity Regulates Angiogenesis and Blood-Retinal Barrier Maturation via Norrin/β-Catenin Signaling. Neuron (2024)

Saptarshi BiswasSanjid ShahriarGalina BachayPanos ArvanitisDanny JamoulWilliam J BrunkenDritan Agalliu

neurologyangiogenesisglutamatergic neuronal activityneuroscienceneurophysiologyblood-retinal barrier maturationophthalmology

Loss of Tbx3 in Mouse Eye Causes Retinal Angiogenesis Defects Reminiscent of Human Disease. Investigative Ophthalmology & Visual Science (2023)

Mark L. DerbyshireSruti AkulaAustin WongKarisa RawlinsEvelyn B. VouraWilliam J. BrunkenMichael E. ZuberSabine FuhrmannAnne M. MoonAndrea S. Viczian

gene expressionangiogenesismouse eyevision researchdermatologyocular diseasehuman diseaseophthalmologymammalian biologyvisual sciencegenetics

Laminin β2 Chain Regulates Cell Cycle Dynamics in the Developing Retina. Frontiers in Cell and Developmental Biology (2022)

cell cycledevelopmental cellretinadevelopmental neurobiologycell biologycellular physiologycell divisiondevelopmental biologydeveloping retinamolecular cell biologyophthalmology retinaophthalmology

Mural Norrin/β-Catenin Signaling Regulates Lama2 Expression to Promote Neurovascular Unit Assembly. bioRxiv (Cold Spring Harbor Laboratory) (2022)

Saptarshi BiswasSanjid ShahriarNicholas P. GiangrecoPanos ArvanitisMarkus WinklerNicholas P. TatonettiWilliam J. BrunkenTyler CutforthDritan Agalliu

vascular biologyangiogenesisneurosciencemembrane biologyneurovascular unit assemblymolecular biologypharmacologygene expressionmolecular regulation

Mural Wnt/β-Catenin Signaling Regulates Lama2 Expression to Promote Neurovascular Unit Maturation. Development (2022)

Saptarshi BiswasSanjid ShahriarNicholas P. GiangrecoPanos ArvanitisMarkus WinklerNicholas P. TatonettiWilliam J. BrunkenTyler CutforthDritan Agalliu

vascular biologyangiogenesisneurosciencedevelopmental biologydevelopmental scienceneurovascular unit maturationdevelopmental neurobiologygene expressiongenetics

Absence of Gpr81 is Associated With Retinal Vascular Leakage in a Knockout Mouse Model. Investigative Ophthalmology & Visual Science (2020)

knockout mouse modelvascular biologyphysiologyretinablood vesselscell biologyneuro-ophthalmologycellular physiologyexperimental ophthalmologyocular diseaseretinal vascular leakageophthalmology retinamolecular neuroscienceophthalmologyreceptors

Physiological and Anatomical Role of Neural Derived Lamb2 in the Retina.. Investigative Ophthalmology & Visual Science (2020)

anatomical roleneural derived lamb2neuroanatomyphotoreceptor cellsretinaneuro-ophthalmologydevelopmental neurobiologyneuronsneurosciencevisual systemophthalmology retinaophthalmologyvisual science

The Role of Laminin β2 in Retinal Vascular Basement Membrane Organization. Investigative Ophthalmology & Visual Science (2020)

vascular biologymatrix biologyretinaganglion cellcell biologycellular physiologymembrane biologylaminin β2ophthalmology retinaextracellular matrixophthalmology

Β2- and γ3-Containing Laminins Regulate the Structure of Optic Chiasm and Retinal Ganglion Cell Axon Sorting. Investigative Ophthalmology & Visual Science (2020)

retinal ganglion celldevelopmental cellretinaneuronsdevelopmental neurobiologycellular physiologyneuroscienceganglion celldevelopmental biologycellular neurobiologyoptic chiasmoptic nerveophthalmology retinamolecular neuroscienceophthalmologyγ3-containing laminins

Conditional Deletion of Lamb2Produces a Novel Progressive Retinal Degeneration. Investigative Ophthalmology & Visual Science (2019)

retinaneuro-ophthalmologyocular diseasevisual systemophthalmology retinaveterinary medicineophthalmologyconditional deletionvisual science

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